Basic Information

Insect: Rhamphomyia laevipes
Gene Symbol: ZNF48
Assembly: GCA_963920725.1
Location: OY987259.1:17292491-17297896[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 6.3 7.4e+02 2.0 4.5 1 11 248 258 248 270 0.75

2 14 0.00018 0.021 16.3 0.6 2 23 324 345 323 345 0.97

3 14 4 4.6e+02 2.6 0.5 1 12 430 441 430 444 0.88

4 14 0.008 0.93 11.1 0.1 1 23 503 526 503 526 0.93

5 14 0.0034 0.4 12.3 0.4 2 23 557 578 556 578 0.97

6 14 1.7e-05 0.002 19.5 0.6 2 23 588 609 587 609 0.97

7 14 0.014 1.6 10.4 2.0 1 23 635 656 635 656 0.81

8 14 0.011 1.3 10.6 2.8 1 23 665 687 665 687 0.97

9 14 0.0005 0.058 14.9 0.8 1 23 709 731 709 731 0.97

10 14 1.8e-06 0.00021 22.6 3.4 1 23 737 759 737 759 0.99

11 14 0.00038 0.044 15.3 3.6 1 23 765 787 765 787 0.98

12 14 1e-05 0.0012 20.3 1.2 1 23 793 815 793 815 0.97

13 14 4.5e-05 0.0052 18.2 0.2 1 23 819 841 819 841 0.98

14 14 0.00046 0.053 15.0 0.1 2 23 851 873 850 873 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	6.3	7.4e+02	2.0	4.5	1	11	248	258	248	270	0.75
2	14	0.00018	0.021	16.3	0.6	2	23	324	345	323	345	0.97
3	14	4	4.6e+02	2.6	0.5	1	12	430	441	430	444	0.88
4	14	0.008	0.93	11.1	0.1	1	23	503	526	503	526	0.93
5	14	0.0034	0.4	12.3	0.4	2	23	557	578	556	578	0.97
6	14	1.7e-05	0.002	19.5	0.6	2	23	588	609	587	609	0.97
7	14	0.014	1.6	10.4	2.0	1	23	635	656	635	656	0.81
8	14	0.011	1.3	10.6	2.8	1	23	665	687	665	687	0.97
9	14	0.0005	0.058	14.9	0.8	1	23	709	731	709	731	0.97
10	14	1.8e-06	0.00021	22.6	3.4	1	23	737	759	737	759	0.99
11	14	0.00038	0.044	15.3	3.6	1	23	765	787	765	787	0.98
12	14	1e-05	0.0012	20.3	1.2	1	23	793	815	793	815	0.97
13	14	4.5e-05	0.0052	18.2	0.2	1	23	819	841	819	841	0.98
14	14	0.00046	0.053	15.0	0.1	2	23	851	873	850	873	0.96

Sequence Information

Coding Sequence: atgaGCAAAAGTTGTGCCGTTGTTGGGTGTCccacaaaattatcaaaaaattattctttgcGTTTGTTCGCCTTTCCAAAAAATCCGGAAATCCGAAGGAAGTGGATTGATGCATGTGGCGATCCACTATTGAATCCAAAtagttcaaaaatttgtaatttacattttgaaGATGAAGATTATCGATTACAAGATCGTCtattaaatattccaaaaatgaaACGTAAATTATTACATACTGCAGTGCCCAAAATATCTGATCCTGATTCCTTAAATGAAGATCTATTCCTCACAAGTAAAagtactgattatttagattttcataCTGATCAAATAATTCTACAAAACTTTGAATCAGAATTTAAACCTGAAAATACAGAATTGAAAACTGTTGCAGTAGAATTTATAGATATCTCTTCATACGAgaacattgaaaataattctaatcaatatacaaaattatataaagattcAGAAGTGCAGTGCAAtttatttgaagaattattGATCGAAAGATCTCTAACTGATAGTAGTGATTGTAATTGTTATGGCTGgttttttgaaataatgaaattgtcaAAAGAAACAGATATAAATGAAGTCCAAATATGTGATTCTGTTgagattgaattaaattataatgaaatcgaaaaaaattgcacaaaaactaaaacaaaaaatattgaaaataaaaagcgAATTCGCcaagataattataataaaagttctaATGACGATGGTTATCAATGTAAGAAATGTGAtaagaaatgtttaaatttagcTGCATATTATGCACATTGTGATAGTCATTTAGAAAAAAGTTCAATTTGTTCAAAATGTGGATTAAATTTAACAAGTCGAAAAATTGCAGCAAATCATGAAAgatattgtattaataaatcaaaaaattctataggaaatgaaaaagaaaatattactatatctaaacgtaaaaataatattaataaaacttgtgGAATTTGTGATCGTACATTTGAAAAATCGGTGACATATATGGATCATATGAATATGCATAATAATTATGAAAATAATAGCTTTCAATATGAATACGAAGTTCATAATATAGAAgatgatgaaaatgaaattgacgatagtaatattgaatatattgaatataataatgaacCCAGTGACATTATTTATGATGGGGATGGAATTTGTATTGAAGATGACATTAACCAAACAGTGGtggataatgaaaatattccaacagaagaaaatattaatttaaatgattcagaTGACGATGTTGATGATGGAGAAATGTATTTTTGTAGtacatgtaatttaaattttaaaaatgttgatgaacatatacaaaattatcattcaAATCAATCAGTAATGATTGAAACTATGCCGGattatgaagaagaaaatagtTTCTTAGAATCAATTAAAGGATCTTTAGAGAATAGTTCTGAATTAactgatgaaaattatattgatattactaataatataaatgagaCTGATGCCAAAGAATTTTTATGCCAAGAATGCGATTTAGTATTTAATGAAGAAATACTTTTGAAATCTCATATTAATGCAAAACATATTAACAAGGAAAGTGCCAATAATGAGGAAACTGAAATGTTAATGGAATCATTAGGAGttagtttacataaaataaaagatgaaaacaCAAAATGTTTAGTTTGTAATACTATTTTCCCTTCAGTCAAAAGCTTAaaattacatGCTCGTATgcataaaacaacaaatttacaTGAAAATACACAGTGTTCAATTTGTAATACAGTTTTTTCATCAGCTAGAAGTTTAaaATTACATGCACGTATGCACAAACcaattgaattgaaaaactATAAAGAAGCACTTGGTCaggaatataaaaatcattttaaaaatattcaatatttccaatgtgaaatttgtggaaaaagatttgATAGTAAACTAAAAgaagaacataaaaaatttcatcaaaatgataaaaaattaaatgaatttgtatgcacaaaatgtaataagaaatttttaaatgaaactagTTTTACAatgcatttaaaattacatgaaaatcaaacatataaaccaaaaaaaccaacaaaagcTGAAGCAGCTGGTATATCATTGCCATATGCATGTCAATATTGTGGGAGAGAATTTGGTCGACCACACGAGAAAGTAAAGCATGAAAGAATTCATACTGgtgaaaaaccatttaaatgtgAAGTTTGTGGTAAATGTTTTCGAGTAACATATTCATTAACATTACATCTAAGGACACATACATCAGCTAGGCCTTATGTTTGTTCTGTTtgcaataaaagatttaaatcatATTCTGTCTATTCACATCATTTACTAACACATTCCGATAAACGTCCATATGCGTGTCCAGATTGCCCGAAAACTTTCAAAACATCTGTACAGTTACATGGTCATAAAAATAGTCATACGAAACCATTTAATTGTCCGGAATGTAATCGTCCATTTGCAACAATGTATGCAGTTAAAACTCATATGGAAActcataaaaaagaaaatactaatttaaaacaACGTTGTTTAATATGTGGTGCAACATATTCTCGTATATTTGCATTAAAAGATCATATGCGTGAAGTACATAatagtaattttgttatatcaGATGAAAAAGATGTAAAAGAAGATGCTGGTGGTGGtgatgatgatattgatgatgTAAAAGATAATATTACAGAAGAAGAAACTGTTTTAATTGAAGAAGAAGAACAAACAGAAATATATGATGACGAAATTGCAGAAGAAGTAGTTACTGATTggttgaaatga
Protein Sequence: MSKSCAVVGCPTKLSKNYSLRLFAFPKNPEIRRKWIDACGDPLLNPNSSKICNLHFEDEDYRLQDRLLNIPKMKRKLLHTAVPKISDPDSLNEDLFLTSKSTDYLDFHTDQIILQNFESEFKPENTELKTVAVEFIDISSYENIENNSNQYTKLYKDSEVQCNLFEELLIERSLTDSSDCNCYGWFFEIMKLSKETDINEVQICDSVEIELNYNEIEKNCTKTKTKNIENKKRIRQDNYNKSSNDDGYQCKKCDKKCLNLAAYYAHCDSHLEKSSICSKCGLNLTSRKIAANHERYCINKSKNSIGNEKENITISKRKNNINKTCGICDRTFEKSVTYMDHMNMHNNYENNSFQYEYEVHNIEDDENEIDDSNIEYIEYNNEPSDIIYDGDGICIEDDINQTVVDNENIPTEENINLNDSDDDVDDGEMYFCSTCNLNFKNVDEHIQNYHSNQSVMIETMPDYEEENSFLESIKGSLENSSELTDENYIDITNNINETDAKEFLCQECDLVFNEEILLKSHINAKHINKESANNEETEMLMESLGVSLHKIKDENTKCLVCNTIFPSVKSLKLHARMHKTTNLHENTQCSICNTVFSSARSLKLHARMHKPIELKNYKEALGQEYKNHFKNIQYFQCEICGKRFDSKLKEEHKKFHQNDKKLNEFVCTKCNKKFLNETSFTMHLKLHENQTYKPKKPTKAEAAGISLPYACQYCGREFGRPHEKVKHERIHTGEKPFKCEVCGKCFRVTYSLTLHLRTHTSARPYVCSVCNKRFKSYSVYSHHLLTHSDKRPYACPDCPKTFKTSVQLHGHKNSHTKPFNCPECNRPFATMYAVKTHMETHKKENTNLKQRCLICGATYSRIFALKDHMREVHNSNFVISDEKDVKEDAGGGDDDIDDVKDNITEEETVLIEEEEQTEIYDDEIAEEVVTDWLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01297478;
90% Identity: iTF_01297478;
80% Identity: iTF_01297478;