Basic Information

Gene Symbol
-
Assembly
GCA_029963845.1
Location
JANEYF010004465.1:84359-85333[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.13 27 7.5 2.2 1 23 19 41 19 41 0.97
2 10 0.0022 0.45 13.1 2.8 1 23 50 72 50 72 0.99
3 10 0.64 1.3e+02 5.3 1.1 1 23 81 103 81 103 0.93
4 10 0.012 2.4 10.8 5.8 1 23 112 134 112 134 0.99
5 10 6.2e-05 0.013 18.0 0.4 1 23 143 165 143 165 0.97
6 10 0.0095 2 11.1 0.1 1 23 174 196 174 196 0.99
7 10 0.0031 0.63 12.6 1.9 1 23 202 224 202 224 0.97
8 10 0.00019 0.039 16.4 1.5 1 23 233 255 233 255 0.98
9 10 0.011 2.4 10.8 3.5 1 23 264 286 264 286 0.92
10 10 0.12 25 7.6 1.2 1 23 295 317 295 317 0.94

Sequence Information

Coding Sequence
ATGAAACTCGAAGGAAACGAGGAGACAGCATTAATCCAACCGACATCACCTTCATTTACTTGTACGCAATGCTCGTACAAAACAAGTGTACTGCGTAGATTGAAGGCGCACTCTCTTAAACACAAGGATCGTTTGACCATGACCATGTTCAAATGTTACAACTGCTCGTTTGAGACGAAACGTAAAACGGCACTTAAAATGCACCTTCTAACCCACAGAGATCCCTCGGAAGTGAAGATGTTCAAGTGTCAGTTGTGTTCTTTTGAAACGATTTGGATAGACTCTCTGAAGAAACACCAGACGAGACATGAATCTTTAAATAAGGGAATTATGTACAAGTGCAAGTTCTGCAGTTATGAGACGAATAAAAAGCATTTACTCAAGTCGCATTTACTACGGCACAAAAGCCCATCGGAAATAACAATGTACAAGTGTGATTGGTGCCCGTACGAGACAAAAAGAAAGGGCAATCTTCGAGAGCATGTAGTGAAACATAAGGAACCTTCCGAGATAACTATGTATAAGTGCGGCATTTGCCCATACGCGACGAAATGGCAGAGCGGGATTAAGGCGCATCGAATGACACATAGAAAACATCCCAGTCACAAGTGTGATAAATGCGATTTTGAAGCAGACAAAAGAAGTGACCTGCTTCGGCACTTACAAAACCATCCAAAGGACGTTTCGTTGAAAATTTACTCCTGCGAACTGTGTGCGTACAGTACTCAATACAAGACGAATCTAAACAAGCATATGAACATGCACAAGGATTCTTCGGAGGCTCCAACGTTTCAATGTGACCAGTGCTCATATGTGACGAAGCATAGGACGGCTCTTAAGAACCATTCTTTTCTTCATATGGACAAGTCGAAGCTTACATTGTTCAAATGTGATTTATGTTCGTACGAGACTTTTAGAAGGAGCATCTTGTTGAAGCACGTCGAAAGGCATAATGTAGCTAAAGAAGAGCACTGA
Protein Sequence
MKLEGNEETALIQPTSPSFTCTQCSYKTSVLRRLKAHSLKHKDRLTMTMFKCYNCSFETKRKTALKMHLLTHRDPSEVKMFKCQLCSFETIWIDSLKKHQTRHESLNKGIMYKCKFCSYETNKKHLLKSHLLRHKSPSEITMYKCDWCPYETKRKGNLREHVVKHKEPSEITMYKCGICPYATKWQSGIKAHRMTHRKHPSHKCDKCDFEADKRSDLLRHLQNHPKDVSLKIYSCELCAYSTQYKTNLNKHMNMHKDSSEAPTFQCDQCSYVTKHRTALKNHSFLHMDKSKLTLFKCDLCSYETFRRSILLKHVERHNVAKEEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-