Basic Information

Insect: Rhagophthalmus giganteus
Gene Symbol: Zfx
Assembly: GCA_036326145.1
Location: JARFJA010000019.1:4722082-4729017[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 39 1.2e-05 0.0011 20.1 0.5 2 23 31 52 30 52 0.98

2 39 0.04 3.7 9.0 1.5 1 23 56 78 56 78 0.97

3 39 0.0028 0.26 12.6 2.6 1 23 113 135 113 135 0.97

4 39 0.17 16 7.0 3.2 1 20 141 160 141 164 0.94

5 39 0.0041 0.38 12.1 4.5 1 23 175 197 175 197 0.97

6 39 0.00052 0.048 14.9 0.6 2 23 203 224 203 224 0.97

7 39 0.00091 0.085 14.2 2.0 1 23 230 252 230 252 0.96

8 39 2.3e-06 0.00021 22.3 1.3 1 23 258 280 258 280 0.98

9 39 0.0021 0.2 13.0 0.2 1 22 286 307 286 307 0.94

10 39 0.085 7.9 8.0 1.7 1 20 355 374 355 378 0.90

11 39 6.5 6e+02 2.0 0.2 1 19 546 564 546 568 0.76

12 39 0.16 15 7.1 1.4 1 23 572 594 572 594 0.97

13 39 1.2 1.1e+02 4.3 0.5 1 23 600 623 600 623 0.90

14 39 0.26 25 6.4 4.9 1 23 629 651 629 651 0.93

15 39 0.011 1 10.8 0.9 1 22 657 678 657 680 0.90

16 39 4.8e-05 0.0045 18.2 3.1 2 23 688 709 687 709 0.97

17 39 2.4e-06 0.00022 22.3 0.5 2 23 715 736 714 736 0.97

18 39 5.3e-05 0.005 18.0 1.8 1 23 742 764 742 764 0.98

19 39 0.0015 0.14 13.5 0.2 3 23 772 792 770 792 0.96

20 39 0.067 6.3 8.3 0.2 1 21 798 818 798 819 0.93

21 39 0.02 1.8 9.9 1.6 2 23 846 867 845 867 0.96

22 39 0.031 2.9 9.3 0.2 1 23 887 909 887 909 0.97

23 39 0.88 82 4.8 1.5 1 23 941 964 941 964 0.95

24 39 0.0015 0.14 13.4 1.7 1 23 970 992 970 992 0.97

25 39 0.00016 0.015 16.5 0.4 1 23 998 1021 998 1021 0.96

26 39 2.9 2.7e+02 3.1 4.5 2 12 1035 1045 1034 1061 0.82

27 39 0.0014 0.13 13.5 1.8 1 23 1067 1089 1067 1089 0.97

28 39 0.0001 0.0096 17.1 0.3 1 23 1095 1117 1095 1117 0.97

29 39 1.4 1.3e+02 4.1 0.1 1 21 1123 1143 1123 1144 0.88

30 39 0.29 27 6.3 1.5 2 23 1283 1304 1282 1304 0.96

31 39 0.067 6.3 8.3 0.1 1 23 1324 1346 1324 1346 0.97

32 39 2.7 2.5e+02 3.2 4.7 1 23 1350 1372 1350 1372 0.91

33 39 0.046 4.3 8.8 1.6 1 23 1378 1401 1378 1401 0.98

34 39 0.0047 0.44 11.9 1.8 1 23 1407 1429 1407 1429 0.97

35 39 0.0012 0.11 13.8 0.6 1 23 1435 1458 1435 1458 0.95

36 39 0.22 21 6.6 3.9 2 14 1470 1482 1469 1496 0.83

37 39 0.00024 0.022 16.0 2.3 1 23 1502 1524 1502 1524 0.98

38 39 5.3e-05 0.0049 18.0 0.6 1 23 1530 1552 1530 1552 0.97

39 39 2.1 1.9e+02 3.6 0.1 1 21 1558 1578 1558 1579 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	39	1.2e-05	0.0011	20.1	0.5	2	23	31	52	30	52	0.98
2	39	0.04	3.7	9.0	1.5	1	23	56	78	56	78	0.97
3	39	0.0028	0.26	12.6	2.6	1	23	113	135	113	135	0.97
4	39	0.17	16	7.0	3.2	1	20	141	160	141	164	0.94
5	39	0.0041	0.38	12.1	4.5	1	23	175	197	175	197	0.97
6	39	0.00052	0.048	14.9	0.6	2	23	203	224	203	224	0.97
7	39	0.00091	0.085	14.2	2.0	1	23	230	252	230	252	0.96
8	39	2.3e-06	0.00021	22.3	1.3	1	23	258	280	258	280	0.98
9	39	0.0021	0.2	13.0	0.2	1	22	286	307	286	307	0.94
10	39	0.085	7.9	8.0	1.7	1	20	355	374	355	378	0.90
11	39	6.5	6e+02	2.0	0.2	1	19	546	564	546	568	0.76
12	39	0.16	15	7.1	1.4	1	23	572	594	572	594	0.97
13	39	1.2	1.1e+02	4.3	0.5	1	23	600	623	600	623	0.90
14	39	0.26	25	6.4	4.9	1	23	629	651	629	651	0.93
15	39	0.011	1	10.8	0.9	1	22	657	678	657	680	0.90
16	39	4.8e-05	0.0045	18.2	3.1	2	23	688	709	687	709	0.97
17	39	2.4e-06	0.00022	22.3	0.5	2	23	715	736	714	736	0.97
18	39	5.3e-05	0.005	18.0	1.8	1	23	742	764	742	764	0.98
19	39	0.0015	0.14	13.5	0.2	3	23	772	792	770	792	0.96
20	39	0.067	6.3	8.3	0.2	1	21	798	818	798	819	0.93
21	39	0.02	1.8	9.9	1.6	2	23	846	867	845	867	0.96
22	39	0.031	2.9	9.3	0.2	1	23	887	909	887	909	0.97
23	39	0.88	82	4.8	1.5	1	23	941	964	941	964	0.95
24	39	0.0015	0.14	13.4	1.7	1	23	970	992	970	992	0.97
25	39	0.00016	0.015	16.5	0.4	1	23	998	1021	998	1021	0.96
26	39	2.9	2.7e+02	3.1	4.5	2	12	1035	1045	1034	1061	0.82
27	39	0.0014	0.13	13.5	1.8	1	23	1067	1089	1067	1089	0.97
28	39	0.0001	0.0096	17.1	0.3	1	23	1095	1117	1095	1117	0.97
29	39	1.4	1.3e+02	4.1	0.1	1	21	1123	1143	1123	1144	0.88
30	39	0.29	27	6.3	1.5	2	23	1283	1304	1282	1304	0.96
31	39	0.067	6.3	8.3	0.1	1	23	1324	1346	1324	1346	0.97
32	39	2.7	2.5e+02	3.2	4.7	1	23	1350	1372	1350	1372	0.91
33	39	0.046	4.3	8.8	1.6	1	23	1378	1401	1378	1401	0.98
34	39	0.0047	0.44	11.9	1.8	1	23	1407	1429	1407	1429	0.97
35	39	0.0012	0.11	13.8	0.6	1	23	1435	1458	1435	1458	0.95
36	39	0.22	21	6.6	3.9	2	14	1470	1482	1469	1496	0.83
37	39	0.00024	0.022	16.0	2.3	1	23	1502	1524	1502	1524	0.98
38	39	5.3e-05	0.0049	18.0	0.6	1	23	1530	1552	1530	1552	0.97
39	39	2.1	1.9e+02	3.6	0.1	1	21	1558	1578	1558	1579	0.86

Sequence Information

Coding Sequence: ATGACCGAAAGCGAGCTGCGTCTACACTTCAGGGAAATCCACAAGGGCAAGCGATTGCGGAATCTGAAACTGCACGTCGAAAATTCCGTGCAGTGCGACATCTGTCCGAAATATTTCCGATCGTTGAAGAGCCTCAAGGAACACATGGAAACGCACAGCAACCAGTTCAACTGCGAGATTTGCAACGCCCACTTCAAGAAGATCCTGGATTACACGATCCACCTCCGGTTGCACTCGCAGGAGGACGTTTTCAAGTGCATCCTCTGCGAGTTCAAGAGCGACTCGATCTTGGACCTGACCGATCATTTGAACACCGCGCACGACGAGAACAACCAGCATAAGTGCAAGCAGTGCGGCAAGGGTTTCTACGTGTTGTCCTGGTTCAAGGAGCACGAGAACTACCACACGGGCGCGAGGCCGTTCGAGTGCGAGTACTGTCTTAAACAGTTTCCGTATTCGCGCTTCTTGACCGCCCACAAGAACTGCGTGCACAAGGAGGACATTCGGAGCGCGCGCAAAATTCACGAGTGCGTCATATGCAAGAAGCAGTATCAGCACAAAAACAGCCTGAAGCTTCACATGAATATTCACCTGGGGAACTTCGCCGTGTGCGATATATGCGGGAAAACTCTGTCGAGCAGGGAAAAGTTGAAGTTTCACATGCGCATCCATACCGGGTACAAGCCGTTCAGTTGCACGTATTGCGGGAAGTGTTTCACCAAGAAACCGATTCTGGTGGAACACGAACGCATCCACACCGGCGAGAAACCTTACACGTGCGAACATTGCTCGAAAGGTTTCTCGCAGCGCTCCAGCTTGGTGATCCACATACGCGGACACACCGGGGAGCGGCCGTACGTCTGTCACATCTGCAATAAGGGCTTCGTCGCGAGGGCCATGCTCAATATTCACTTTAAGACTTGCAAGGGGTTTGAACCGTCGTATCGAAATTCCCCAGAAAATTTGCCCGGCGTTACGAGAATAAAAGTCGAGTACGCGACAGGTTACGAGGACGACTCGCGCACAAAACACAAACGATCCGGCGAGGGAGCTAAAAAGCTATACAAGTGTAAGGTTTGCTTGCAGAAGTTCCACACGTTGCCCGAGCTCGAGAAACATTCCGACGAGAACCATCCGATCTTGGGGAAACGGGCGCGCACTACGAAAATCATCGATACGTCCGAGTGTTTCGACGAGGACGACGACCAGGACGGCGGGAGCTCCGACGACGATAGCGACGACGACGCGTTCGAGATCGAACTGGGAGACGCCAGCACGTTCAACATCGATAAGTTGAAGGAGATCTTCGCGACCAAAATACGCCCGGAGAAGAACTCCACGAAGATAGAATCCGTGTGCGTGATTTGCAACGACGGGAAAAAGTTGTCCAAGGAACTACTGATCGAGCACTACAAAAGTCACAAAAAGGAGGAGATTCCGCCCGAGGTGAATCTGGAAATTAAACGCGAAGAAGCTGCCAATTATTATTGTCACATGTGCAAGGACGacaaaaaaatgacgaaaaacAATTTGAGGGAGCATTATCAGTCCGTTCATAAAATGACCGTCAGCAATAAGAAGCAGTTTTTTAGGAAGGCGCGTTCCAAACGGCCCAGATCGCCCAGACCGGAAATATTCAGGTGCGAAATTTGCTCGATGGAGTTTTTGACTCAACTTCTTCTCGATGAACATTTTGACGGGCACGATTACCAATACTCCTGCGACTTTTGTAACACCGGTTTTAAGAAGTTGATAGATTACACTTTTCACATGCAGATTCACAGCGACGACAAATTGTACAAGTGTCCGTTGTGCCAGTTCGTCACCGACAAGGGTTACCTAGTGAAATCGCATTTGTATTCGGTACACGAGcagttcaaaaaatataaatgcgACAAGTGCAATAAGGGCTTCGCGATTTTCACGCACTTTCAGGAGCACAAATATTTCCACACGGGCGAGAAACCGTTCGAGTGCGACATTTGCGGTCAAAAGTTCATGTACACGCGCTACTTAAACTCCCACAAGGTTCAGATGCACAACTCCGCCCAAAAAGGGATCGAATGCAAAATCTGCAAGAAGATATATTCGCATAGGAACAGTTTAAATACTCATATGAAATCGCACACGGGAGTCGTGTCCGTTTGCGATGTTTGCGGCAAGACGTTCAGCAGTAACGAGAAGCTGCGTTTACACTACCGCATTCACACCGGCGAGAAACCGTATAAATGCGACTATTGCGAGAAAACTTTCAAGACGAGCTCCTATCGTGCCGAACACGAGCGAATTCATACCGGCGAGAAACCGTACGGGTGCCCTTTTTGCGGTAAGGGCTTTTCGCAACGCACCAGCATGGTGATTCACTCGCGCGGCCATACAGGCGAAAAGCCCTACCTATGTCACTTATGTAGTAAAGGTTTCGCGGCCAAGTCCATGGTTACCATTCATTTGAAAGTAAGCGACATGATAAAATTAGAGAAATCAATCGATTACGAAAACGTGGACGAGAAGATCGCGACAAAGAAACACCAGTGGAACTGCGGCAAGTGCAAAGCGGGTTTCGAAACGTCGAGGCTGCTGCACGAACATCGAAGGAGCCATCGTAAAAGAAAGGACGACGTCCAGTACAGTTATAAGTACGACGAGGACCGCGACCTCTTCATTTGTTTCAACTGCGACGTGAAGCTGTCCAGCAAAGAGGAGATGGAGAAGCACGTGTTGGTGCACGAAGACAAATTCATATGCATTATCTGCAACCAGAATTTCGCGAAACCGTACGAATACACGTGTCATCTCTTCAATCACGACAAGAGCAAGGGGTTTCGATGTCCCTTTTGCAAGTACGGTACGAGTACACGTACCATAATTAAGAACCACATAAACTCCTTCCATTTGCGGAAGTTCATCTATAGGTGTTCACTTTGCGGTAAGGGGTTCAACAATTGCTCCGTGTATAAAGAGCACGGAAACGTCCACGAAGGCATAAAGCCGTATCGGTGCGTGGTGTGCAACAAGGAGTTTGCGTTTTCGAGTTACCTAATTGCCCATCAAGTACGCAACCATAAGGTGACGATCGAAGGGATGATCGACACCAACCAAATCAAATGTCACATTTGCCCGAAGAGCTTCGCCCCCAAGAATAGAAACGGTCCCGAGAAGTTGCGTTTACATTACCGCATTCACAACGGCGAGAAACCGTTTAAATGCGACTACTGCGAGAAAACCTTCAAGAAGAGCTGGTATCGTGTCGAACACGAGCGAATTCATACCGGCGAGAAACCGTACGAGTGCCCTTTTTGCGGTAAGGGTTTTTCGCAACGCACCAGTATGGTGATTCACTCACGCGGTCATACGGGCGAGAAGCCCTACCTATGTTACTTGTGTAATAAAGGTTTTGCGGCCAAGTCCATGGTAGCTATTCATTTTAAGTCGTGTAGGGTTGCTGGTGTATGTGTTGAGCATAAAACGTCCGGTATATTAATAATCACTAGCTTAATAGTTTTTCGTACTCCCGTACTCGGCCACCAGAGTCCGATATGTGGCCCGCATTCTCTCCCTTCGCATACCGTGGACAGCCGAATCTGCTTCTCCCTATCTTCAACACTTATATTGGTATTGAAGGTAGGAGAGCAGGTTGGTCCCGGTTTTTGGTTGTCCAAGACATGTGGAGAGAGCGAATACGGGTCACATATCGGACTCCAGTGGCTGGAAAGATCTGACCGGTGTAGAGTACGGGAAAGCCAAAAGGGGCGAAGCACCTGGAGAGTGAGCGACGTGATAAAATTAGAGAAATCAATTGATTACGAAAACGTAGACGAGAAGATCGCGGCAAAGAAACCTCAGTGGAACTGCGGCAAGTGCAGAGCGGGTTTCGAAACGTTGAGGATGCTGCACGAACATCGAAAAAGCCATCGTAAAGAAAAGAACGATGGTCAGTACAGTTATAAGTACGACACGGATCGCGATCTCTTCGTTTGCTTCACCTGCGACGTAAATGTGCCCAACAAAGAAGAGATGGAGAAGCACGTGTTGGTGCACGAAGGCAAATTCATGTGCGAGGTCTGCCACCAGAATTTCGTGAAACCGTACGAATACACGTGTCATCTCTTCAATCACGATAAGAGCAAGGGGTTTCGATGTCCCTTTTGCAAGTACGGCACGAGTACGCGTACCGTAATTAAGAACCACATCAACACCTTCCATCTGCGGATGTTCATCTATAGGTGTTCGCTTTGCGGTAAGGGATTCAACAATTGTTTACTGTATAAGGAGCACGGAAACGTTCACGAAGGCATCAAGCCGTTTCGGTGCGTGGTGTGCAGCAAGGAGTTCCCGTTTTCGAGTTACCTAAGTGCCCATCAAGTACGCAACCATAGGGTGACGATCGAAGGGATGATCGGCACCATTCAATGTCACATTTGCCCGAAGAGCTTCGCCCGCAAGAATAGCAATGGTCCCGAGAAGTTGCGTTTACATTACCGCATTCACAACGGCGAGAAACCGTATAAATGCGATTACTGCGAGAAAACCTTCAAGAAGAGCTCGTATCGCGTCGAACACGAACGAGTTCATACCGGCGAGAAACCGTACGAGTGTCCATTTTGCGGTAAGAGATTTTCGCAACGCACCAGCATGGTGATTCACTCGCGTGGCCATACGGGCGAGAAGCCCTACCTATGTTACTTGTGTAATAAAGGTTTCGCGGCCAAGTCCATGATTGCCATTCATTTTAAGTCGTGTAGGGCCACCGAATCCGAGTGGACGGCTGAATGGCTGGATAGTCCAGATTACGAGAGAACTTAA
Protein Sequence: MTESELRLHFREIHKGKRLRNLKLHVENSVQCDICPKYFRSLKSLKEHMETHSNQFNCEICNAHFKKILDYTIHLRLHSQEDVFKCILCEFKSDSILDLTDHLNTAHDENNQHKCKQCGKGFYVLSWFKEHENYHTGARPFECEYCLKQFPYSRFLTAHKNCVHKEDIRSARKIHECVICKKQYQHKNSLKLHMNIHLGNFAVCDICGKTLSSREKLKFHMRIHTGYKPFSCTYCGKCFTKKPILVEHERIHTGEKPYTCEHCSKGFSQRSSLVIHIRGHTGERPYVCHICNKGFVARAMLNIHFKTCKGFEPSYRNSPENLPGVTRIKVEYATGYEDDSRTKHKRSGEGAKKLYKCKVCLQKFHTLPELEKHSDENHPILGKRARTTKIIDTSECFDEDDDQDGGSSDDDSDDDAFEIELGDASTFNIDKLKEIFATKIRPEKNSTKIESVCVICNDGKKLSKELLIEHYKSHKKEEIPPEVNLEIKREEAANYYCHMCKDDKKMTKNNLREHYQSVHKMTVSNKKQFFRKARSKRPRSPRPEIFRCEICSMEFLTQLLLDEHFDGHDYQYSCDFCNTGFKKLIDYTFHMQIHSDDKLYKCPLCQFVTDKGYLVKSHLYSVHEQFKKYKCDKCNKGFAIFTHFQEHKYFHTGEKPFECDICGQKFMYTRYLNSHKVQMHNSAQKGIECKICKKIYSHRNSLNTHMKSHTGVVSVCDVCGKTFSSNEKLRLHYRIHTGEKPYKCDYCEKTFKTSSYRAEHERIHTGEKPYGCPFCGKGFSQRTSMVIHSRGHTGEKPYLCHLCSKGFAAKSMVTIHLKVSDMIKLEKSIDYENVDEKIATKKHQWNCGKCKAGFETSRLLHEHRRSHRKRKDDVQYSYKYDEDRDLFICFNCDVKLSSKEEMEKHVLVHEDKFICIICNQNFAKPYEYTCHLFNHDKSKGFRCPFCKYGTSTRTIIKNHINSFHLRKFIYRCSLCGKGFNNCSVYKEHGNVHEGIKPYRCVVCNKEFAFSSYLIAHQVRNHKVTIEGMIDTNQIKCHICPKSFAPKNRNGPEKLRLHYRIHNGEKPFKCDYCEKTFKKSWYRVEHERIHTGEKPYECPFCGKGFSQRTSMVIHSRGHTGEKPYLCYLCNKGFAAKSMVAIHFKSCRVAGVCVEHKTSGILIITSLIVFRTPVLGHQSPICGPHSLPSHTVDSRICFSLSSTLILVLKVGEQVGPGFWLSKTCGESEYGSHIGLQWLERSDRCRVRESQKGRSTWRVSDVIKLEKSIDYENVDEKIAAKKPQWNCGKCRAGFETLRMLHEHRKSHRKEKNDGQYSYKYDTDRDLFVCFTCDVNVPNKEEMEKHVLVHEGKFMCEVCHQNFVKPYEYTCHLFNHDKSKGFRCPFCKYGTSTRTVIKNHINTFHLRMFIYRCSLCGKGFNNCLLYKEHGNVHEGIKPFRCVVCSKEFPFSSYLSAHQVRNHRVTIEGMIGTIQCHICPKSFARKNSNGPEKLRLHYRIHNGEKPYKCDYCEKTFKKSSYRVEHERVHTGEKPYECPFCGKRFSQRTSMVIHSRGHTGEKPYLCYLCNKGFAAKSMIAIHFKSCRATESEWTAEWLDSPDYERT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -