Basic Information

Gene Symbol
-
Assembly
GCA_036326145.1
Location
JARFJA010000019.1:4686726-4690339[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 28 0.077 7.1 8.1 2.2 1 23 14 37 14 37 0.93
2 28 0.00062 0.058 14.7 1.4 1 23 43 65 43 65 0.97
3 28 0.026 2.5 9.6 3.1 1 19 71 89 71 94 0.92
4 28 0.0029 0.27 12.6 6.1 1 23 99 121 99 121 0.97
5 28 1.1 1e+02 4.5 4.7 1 23 130 151 130 151 0.92
6 28 3.6e-05 0.0033 18.6 0.1 1 23 158 180 158 180 0.98
7 28 0.00043 0.04 15.2 1.6 1 23 186 208 186 208 0.97
8 28 1.4e-05 0.0013 19.8 1.1 1 23 214 236 214 236 0.99
9 28 2.6e-05 0.0025 19.0 2.8 1 23 242 264 242 264 0.98
10 28 2.9e-07 2.7e-05 25.2 1.3 1 23 286 308 286 308 0.98
11 28 0.011 1 10.7 6.2 1 23 313 336 313 336 0.95
12 28 9.9e-05 0.0092 17.2 1.9 1 23 342 364 342 364 0.97
13 28 0.021 1.9 9.9 4.2 1 23 370 393 370 393 0.96
14 28 0.0013 0.12 13.7 8.5 1 23 398 420 398 420 0.98
15 28 0.00026 0.024 15.9 1.8 1 23 429 451 429 451 0.99
16 28 6.1e-06 0.00057 21.0 1.0 1 23 458 480 458 480 0.97
17 28 0.00046 0.043 15.1 4.0 1 23 486 508 486 508 0.96
18 28 3.4e-06 0.00032 21.8 2.9 1 23 514 536 514 536 0.99
19 28 0.00015 0.014 16.7 3.4 1 23 542 564 542 564 0.97
20 28 0.00078 0.073 14.3 3.2 1 23 611 634 611 634 0.90
21 28 0.021 1.9 9.9 2.7 1 23 640 662 640 662 0.96
22 28 5.5e-05 0.0051 18.0 1.7 1 23 668 691 668 691 0.93
23 28 0.2 19 6.7 0.2 1 23 696 718 696 718 0.97
24 28 0.017 1.6 10.2 0.8 1 23 727 749 727 749 0.97
25 28 9.3e-06 0.00087 20.4 1.1 1 23 756 778 756 778 0.97
26 28 7.6e-05 0.0071 17.5 1.7 3 23 786 806 785 806 0.99
27 28 0.019 1.8 10.0 2.4 1 23 812 834 812 834 0.97
28 28 1e-05 0.00097 20.3 1.0 1 23 840 862 840 862 0.98

Sequence Information

Coding Sequence
ATGAAACGTCACAGACGATACCAGCACACCGACAAAATACATCCGTGCGACAGCTGCGACCGAAAATTCAAATTCCCGCACGAGGTGGCGCTTCATAAAAACCAAGTGCACATCAAGGATTTTCGACACGAGTGCGATATCTGCAATAAACGCTTCGCGGTGAAAATAAAACTGGTTTATCATCGAAAAATCCACTTCAAGGATTATCCGTATAAGTGCGACGAGTGCAACAAGGGCTTCCCCTCTAAGACGGTCTATCGGCAGCATTGCGACGTCAAGCACCGAGGCGTACGTTTTTGCTGCCAGCACTGTAAAAAGATTTTCAGCAACGAGCCCTACTTTAGGCAGCACGTCCTAACCCATAATCCCGATTTCGtcaaaaaactgtttaaatgCGAGGTGTGCGACAAATTCATGCATCAGAGGAGTTACTTGCGCCACAAACAAATGCACAGCGGCAACGGTAGTCAGTACGTTTGCGACGTTTGCGGAAAATCGGTGACCACGCTGATGAGCTTGAACGACCACTTGAAGCTGCATTCCGGCGAGAAGTCGTTCGCGTGTAAATACTGCGGAAATAAATTCAGGAATCGTTCAATTTTAACGTTACACGAACGAACGCACACCAAAGAAAAACCGTACAGTTGCGACGTGTGTTCGAAGAAGTTTACCCAGAGGGGACCGTTGACCATCCATAAACGTACCCATACTGGCGAGAAGCCGTACGAGTGTCATATTTGCGTCAAGAAATTCATTTCGAAAACGTTGTTGACTAGCCATCTTAAATCGCACGGCACGGCTTTAACTAAGTGCCTCAAATGGACCATGCGAAGTAAAAGGAAATCAAGTAAATCCTTCGAATGCCTAGAGTGTGACAAAGTATTCAGGCAGTCCTCGTCGCTGAAACGTCACAAACAAATCCACCTGAACCAGATGCATCGGTGTGACGTTtgtaacaaacaattcaaaactCAATATCTGATGTCTGTACACAAAAAGCACCAGCACACTAAAAAACTGGAGCACGTCTGCGACGTGTGCGACAGGGCCTTCCCGTACAAGTACAAGTTGACCTATCATCGAAAAATTCACTTCGCCGCGAAAAGGTTTCAGTGCGACAAGTGCGACAGCTCGTTTCACTACTACAGCGGATACCAGAGGCACTACACGATTCAGCATCAAGGATTGCGCTTCAGTTGCGATCACtgtaaaaaatcgtttaaaaatcaatattctCACAAACAACACATGTTAACTCACGATCgttatttcgttaaaaaagaATACAAATGCGACGTGTGCGACAAAGTGCTGCAACACTCGAAAACTCTCGATCTTCACATGAAAATGCACAACAACGAAAGGGAACAGCACGTGTGCGACATTTGTGGAAAGTCGCTGACGTCGGCGCACAGCCTGAACGATCACATCAAAGTGCATTCCGGCGAAAGACCGCACCCGTGCGACAGCTGCGAGAAGAGGTTCAGGACGCGCAAGCACTTGAAGGTTCACGAGCTCGTGCACACCAAAGAGAAGCCGTACACGTGCAAGGTGTGTTCGAAGAGTTTCTCGCAGTGCGGAACGTTGGCTATTCACATGCGGTATCACACGGGAGAAAGGCCGCACGCGTGCCACATATGCGAGAAGAAATTCGTCACCGGGACGCTGTTGAAAAGTCACATTAAAACGCACGGCACCGTTCCCTTATCGCTCGTAGCACCCGCTCTTCTGACCTATCAAGTCTTTCAAGTGGTCTACAATCCTGTGTTACGAACAACTGGGATTGGGTTACCAATCATCCAGACGCCGCCAAAACCCATCGAATTAAACTATCGATGCAAGTATTGCGAGAAATGTTTCAGATACCAGAGTCAAGTTGATTCCCACGAAATACAAGCGCACACCAAGAATTACCAATACAATTGCGATATGTGCGATAAATCGTTTCCGTTCGAGTGTAGACTGGCGTATCATCGAACGATGCACTTGAAAGGATACCGATTCAAGTGCGAGAAATGCGACAAAAGTTTCCCGCGCAAAATACGACTACAGATACATCAATTCCTTCAACACGAAAACATCACGTATTTCTGTGGACTCTGTAATGATCCGTTCGAAAATGAAAAGAGTTTCGAAACGCATGCCGCGACTCACGGCCCCGATAAAGTCGCAGCGTCGTACAAATGCGACGTGTGCGGCAAAGTGTTGCCATGCCTAAAAACCTACGTTAAGCACATGGAAATTCACAGCAACGACAGGTATCTGCACGTGTGCTACGTTTGCGGCAAATCCGTGACCTCGTCTACGAGCTTAAGGGACCACATGAAGGTACATTCCGGAGAAAAGCCGCACGGGTGCAGTTTTTGCGACAAGAAATTCAGCAACCGTAAATTATTGTCCGTTCACGAACGAACGCACACCAAAGAAAAACCGTACGCTTGCGACCAGTGTCCGAGAAAATTCGCGCAGTGCACGGCACGGACCGTGCACAAGCGCTACCATTCAGGCGAAAGGCCGTTTCAGTGCAACATATGCGGCAAGGGGTTCATCACCAAAACCGTGTTAAAGTATCACCTTAAAAATCACACGGCTTTGGGAGAGTGA
Protein Sequence
MKRHRRYQHTDKIHPCDSCDRKFKFPHEVALHKNQVHIKDFRHECDICNKRFAVKIKLVYHRKIHFKDYPYKCDECNKGFPSKTVYRQHCDVKHRGVRFCCQHCKKIFSNEPYFRQHVLTHNPDFVKKLFKCEVCDKFMHQRSYLRHKQMHSGNGSQYVCDVCGKSVTTLMSLNDHLKLHSGEKSFACKYCGNKFRNRSILTLHERTHTKEKPYSCDVCSKKFTQRGPLTIHKRTHTGEKPYECHICVKKFISKTLLTSHLKSHGTALTKCLKWTMRSKRKSSKSFECLECDKVFRQSSSLKRHKQIHLNQMHRCDVCNKQFKTQYLMSVHKKHQHTKKLEHVCDVCDRAFPYKYKLTYHRKIHFAAKRFQCDKCDSSFHYYSGYQRHYTIQHQGLRFSCDHCKKSFKNQYSHKQHMLTHDRYFVKKEYKCDVCDKVLQHSKTLDLHMKMHNNEREQHVCDICGKSLTSAHSLNDHIKVHSGERPHPCDSCEKRFRTRKHLKVHELVHTKEKPYTCKVCSKSFSQCGTLAIHMRYHTGERPHACHICEKKFVTGTLLKSHIKTHGTVPLSLVAPALLTYQVFQVVYNPVLRTTGIGLPIIQTPPKPIELNYRCKYCEKCFRYQSQVDSHEIQAHTKNYQYNCDMCDKSFPFECRLAYHRTMHLKGYRFKCEKCDKSFPRKIRLQIHQFLQHENITYFCGLCNDPFENEKSFETHAATHGPDKVAASYKCDVCGKVLPCLKTYVKHMEIHSNDRYLHVCYVCGKSVTSSTSLRDHMKVHSGEKPHGCSFCDKKFSNRKLLSVHERTHTKEKPYACDQCPRKFAQCTARTVHKRYHSGERPFQCNICGKGFITKTVLKYHLKNHTALGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-