Basic Information

Gene Symbol
-
Assembly
GCA_958510855.1
Location
OY294042.1:27668341-27671604[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.00062 0.041 15.3 0.3 1 23 87 110 87 110 0.97
2 10 0.022 1.5 10.4 4.6 2 23 198 220 198 220 0.91
3 10 0.57 38 6.0 0.1 2 20 474 492 473 496 0.84
4 10 0.00033 0.022 16.2 0.9 2 23 561 583 561 583 0.95
5 10 0.18 12 7.5 0.1 2 23 608 630 607 630 0.93
6 10 0.016 1.1 10.8 3.6 2 23 676 698 675 698 0.96
7 10 0.24 16 7.2 3.7 3 23 713 734 711 734 0.92
8 10 0.0004 0.026 15.9 1.3 2 23 784 806 784 806 0.96
9 10 0.31 21 6.8 0.2 1 23 880 902 880 902 0.97
10 10 0.00024 0.016 16.6 3.1 2 23 915 936 914 937 0.95

Sequence Information

Coding Sequence
ATGACGACATCCGCCACTTTACCCTCCACAACGGGACCGGTACATGCTGGCGGCTTTTCTGCAATATCCGAAGACACCGTAGTTCACGAAGCCGCTTTCGAGATACCAAGAAATATAAAACGTTGCTTAATTGCCCCGCTCACCGACTCCTGCAAGAAGCGACGAAAACAAGCTACTCCTGTTCGCATTTCTGCTGCTGATTCAGAACTAATTTCTTCAGAAGGTAAGCTGCCCGTTGCATCTCCCGAGCCCGATGTTTTTCGGTGCCCTCTGTGCCAACTCGCCTTTAATAAAGCAGAGCGACTTCAAAATCATATTACGACTGAACATGTTAGTGTTGAATGTAAAAAAGAACCCGAGGATGCTTCTTCTAATAATTACGAGCGTTCTGAAACTGCGATCGAGTTGCCTGTTGCTTCCAGAAGTGATGTATCATGGAGAAGTGATTTGCAAAATAACGAATGGATTAACCCAAACTTACATGGAATGCCTTTTTCTCCAGCAACCCCATTATTTATGACGCTACCATCCTTCGCGCAGCCCGACAACATTCCCACAAGGCAACCTGTTAGAATATTCAATCCGGACGCGTACTGCGATTTGTGTAATAAAGAATTCTgcaataaatactttttaaaaactcataaaGCAAACAAACACGGTGTTTATACCGATCCACCTGTAACGGAAAATTCGGGAACGTCCGTAAACATTCCATCGTTTTCGACAAGTTTGAAAGTACCAACAACTCCCATTTCTATTAAAACCGAGAACTCGTCAAGCAAATCAGATCCTAATAAAACTCCAACAAATTCAATAAATCAATTCAGCGACATTTTTCCCAATAATCCTAACCTTTTCACCAACAAGCTATTTCCTAAAATTCATAAATCCAACATCCAAGGATTATTTGATTCGGACACATCGGAAAACGCAACCATACCAGATTTTAATGCAACGTCGGGATTAAGCAATGGACAAACAGACCGAAATAATATTTCCTTCGACGATACCACAACCGAAGACACATTAAGTCCCAAAGTAATTCAACACGATCCCATGCTGTTCaaaaacgaatttaattttgaagatgGTACGTTTTTCACATCTCCCGATAAAATGTCGCCAAATCAACAAATTAGAGAATTAGATGCACAACGTTTGAGAAGAATTGGCGTTATGAATCCCAAGGCGTTTTGCGAAATATGTTGCAAGGagtattgtaataaatattttttacgtaCGCACAAAATGAAACGGCACGGAATTTATATACCAGACGACGGCAAGGACAGTAAAGACGGAAGGATGGAATCGAACTGGACCCACAATATGCAAACGAGTCCGCTAAATCTGATAATGGCAGAACAAAATAATTCCAACGCGTCGGAACGAAAGACGTCTTCGCCTGCCGATATTAGTTGCGATTTGTgtggaattaaatttcaaaatgccAGTTTAGCTCAATTACATAACGTGAGTGTACATTCAAGAATCAATCCTGCCGGGCAAGATTTATCGGATGTTTGTAATGACGAGATTGTCGAAAACAATATTGCGGAAACGAATGGAAACggagaaaaaaatattaattcggccGATGCAATTAGTgaagatttacaaaaattacaaaccaTGATACTTCAATTAAACGATTTGGATGTTAGCAGAGCTGCAAATACTTGCACAGTTTGCAGTAAAGAATTTGAGAATCGTTATTACTTACATGCACATATGATGGCGGAACATAGTTTATTAGTTGACGAAGGTGCGGATATGGACAAAAGTGAGGATAATGAGGttggaataaataataacacGGTGTGCGATTTATGCAATAAAGAAGTTCAAAATATAGACGATATGAAAAAGCATATATTGGAATCGCATTCGAATCATCAGAACGCAAACGATATGCGGGATGACGGTTTCGGCAACGCCGAGAAAGCGTTAATTCGAGCTAATTCTTCGGGCGTTCAATTTTCGGAAAGGCGCAGCTCCATGAACCTGACACCTAGTAGCAGTTATTGCGAAATTTGCAATAAGGAGttgtgtaataaatattttatgaaaactcacATGCAACGAATGCACGGAATTGAAATAGAAAACGGCGCGCAAATAGGTGGAGTTATTTGTGACATTTGCAATAAAGAACTTTGCAGTAAATACTTTCTTCGAGTGCACAAACATAATACGCATGGAATAGTCGAATACGGTTCAAGTTTATTGCAACCTCGTAAAAGTGATATCGAACCACCGCCTTTGTTACCAGTCGAACCAGATACCGCACTAAAACCTAGCGATCTCGCCGATCTTAGTCATCGTTATTTCACACATTTTACAGAAGTTTGCACAATTTGCAGTCGTCGTTTTCGTAGTACAAAATGGTTAAAGACGCATTTGCTAACCGATCATGGGCAAGCAGGTGCGGAGAAATGGGCCGAGTTAGAACAACAGCTACAACAATCAATGAATCAAAATTCTAAATCATCCGTAAAAACGCCACAAAGTGAACGATCTAGTCCAACATTAAAGATTCCAAACGGTAACAATAATCACGAAATAACATCAAAAATTGGAATTCAAAACGTTTTATCGACTATATTTGGTGCCGACGAAAATACACCAAAAAGTTACAATTGTTCCTATTGTCCTTTTTCCACGCCCGTCCTTCCTTTCTTATTTATACACGAACGTTCTCACACGATACCAAGTAACGAAAGTGACAACGCATCATTAAAATGTCCAGTTTGCACACAAAGTTTTACACAAGGCGAACAACTTCAACATCACATTTTTACACACCACCCGTTTCTTCCATTACCTCCTCTTTTTAACGGTAATGGAGAACAACCAGAAGTGAACAATACATCCACTGATACGAACGCGGCTGCTGAAAATTCGGATGGTGCCGAAGAAGATTCAAGAACAGAAGAGTCTGCGTCATCTCCTCCTTCGGAAAGCAACAAACAACTAATGGGAATGCAAGTGAAAAAGATGAAGCGCAAAATAAATCGTTTCGAGCTGTCGTCTGAAGTGGGTCAGTCGTTGAAAGATGTAGCGAAAAGATCACAGCTTCCCGCATCTTATGCATTACCACAAAATGGCGAACAAGAAGTTACATCTGGGTATGTTATGCAAGCTTTTTTAGTTGACGAACCGGCAGTAGAACGAAAGTTTGTACCGTCCGTGGTATTTCTACCGGTTTTGCAAAAGCAATCGGCTCCTATTAACGTAACATTCACTCTTACCCCAGCTTAA
Protein Sequence
MTTSATLPSTTGPVHAGGFSAISEDTVVHEAAFEIPRNIKRCLIAPLTDSCKKRRKQATPVRISAADSELISSEGKLPVASPEPDVFRCPLCQLAFNKAERLQNHITTEHVSVECKKEPEDASSNNYERSETAIELPVASRSDVSWRSDLQNNEWINPNLHGMPFSPATPLFMTLPSFAQPDNIPTRQPVRIFNPDAYCDLCNKEFCNKYFLKTHKANKHGVYTDPPVTENSGTSVNIPSFSTSLKVPTTPISIKTENSSSKSDPNKTPTNSINQFSDIFPNNPNLFTNKLFPKIHKSNIQGLFDSDTSENATIPDFNATSGLSNGQTDRNNISFDDTTTEDTLSPKVIQHDPMLFKNEFNFEDGTFFTSPDKMSPNQQIRELDAQRLRRIGVMNPKAFCEICCKEYCNKYFLRTHKMKRHGIYIPDDGKDSKDGRMESNWTHNMQTSPLNLIMAEQNNSNASERKTSSPADISCDLCGIKFQNASLAQLHNVSVHSRINPAGQDLSDVCNDEIVENNIAETNGNGEKNINSADAISEDLQKLQTMILQLNDLDVSRAANTCTVCSKEFENRYYLHAHMMAEHSLLVDEGADMDKSEDNEVGINNNTVCDLCNKEVQNIDDMKKHILESHSNHQNANDMRDDGFGNAEKALIRANSSGVQFSERRSSMNLTPSSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVICDICNKELCSKYFLRVHKHNTHGIVEYGSSLLQPRKSDIEPPPLLPVEPDTALKPSDLADLSHRYFTHFTEVCTICSRRFRSTKWLKTHLLTDHGQAGAEKWAELEQQLQQSMNQNSKSSVKTPQSERSSPTLKIPNGNNNHEITSKIGIQNVLSTIFGADENTPKSYNCSYCPFSTPVLPFLFIHERSHTIPSNESDNASLKCPVCTQSFTQGEQLQHHIFTHHPFLPLPPLFNGNGEQPEVNNTSTDTNAAAENSDGAEEDSRTEESASSPPSESNKQLMGMQVKKMKRKINRFELSSEVGQSLKDVAKRSQLPASYALPQNGEQEVTSGYVMQAFLVDEPAVERKFVPSVVFLPVLQKQSAPINVTFTLTPA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00951343;
90% Identity
iTF_01292961;
80% Identity
-