Basic Information

Gene Symbol
-
Assembly
GCA_958510855.1
Location
OY294038.1:60353289-60354458[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 2e-05 0.0013 20.0 2.9 1 23 79 101 79 101 0.98
2 11 0.0016 0.1 14.0 1.7 1 23 107 129 107 129 0.98
3 11 2.4e-05 0.0016 19.7 0.8 1 23 135 157 135 157 0.98
4 11 0.39 26 6.5 5.5 1 23 163 184 163 184 0.88
5 11 0.0019 0.12 13.8 4.1 1 23 190 212 190 212 0.98
6 11 0.00028 0.018 16.4 1.5 1 23 218 240 218 240 0.97
7 11 9.9e-05 0.0066 17.8 0.5 1 23 246 268 246 268 0.98
8 11 0.0037 0.25 12.8 3.2 1 23 274 296 274 296 0.97
9 11 0.001 0.068 14.6 1.1 1 23 302 324 302 324 0.98
10 11 0.4 27 6.5 2.5 1 23 330 353 330 353 0.94
11 11 0.0043 0.29 12.7 2.2 1 23 359 381 359 381 0.97

Sequence Information

Coding Sequence
ATGGAAAAGGCGATACTGATAGGAGAATATTTGGAAGTAAAAGAAGAAACCGAGGAAGAGAAAAAGGTCAACTTGCAAGATTTGCACCATtccattgatattaaggaagacCAGCCTTCTGGATCGGAAGTACAAATATTCCATCCATTTAAATCCGATTTAtctaacctaaaatttactAGTCAAACACAAGACAGAAAATATACAAAAGATCAACCTGCTACTCCTAAAGTGTTTTCCTGTGAACTGTGCGATTATAAATGTTCAATGAAAGGAAATTTAACGACCCACATtagaactcataccggtgagaagcCATTTACGTGTTCAATTTGCGATTTTTGCAGTGCACGCAGCACAGTTTTAAGGGATCATTTAAAAGTCCACactggcgaaaaaccgtttcCTTGTGATgtttgtgactataaaggtTCAACCAAACTAAATCTAAAGCGTCACATGACAACTCATaatggtgagaaaccgttttcgtgtgatatttgtgactatacATGTTCcactaatattttaaaacagCACATGAGGATTCATACCGGAGAAACACTATTTTCCTGTGAATTTTGTGATTACAAGTGCGCAATGAAAGGTCATTTGGTTACGCACGTCagaactcatactggcgagaagCCGTTCAATTGCgcaatttgtgactttaaatgtgcaCGCAAAGCAAGTTTAAAGGATCACTTAAAAGTTCACTCGGGCGAAAAACCGTTTCCTTGTGGAATATGTGACTATAGAAGTTCAAACAGACTAACTTTGAAACGGCATATGGTGactcataccggcgagaaacctCATATGTGCACCATTTGTGACTTCAAAAGTGCACATAAAGTAAGTTTGAAAGATCACTTAAAAATtcataccggggaaaaaccgttttcGTGCGAAAAATGTGTCTATAAAAGTTCTAATAAATTAGCTTTGAAGCGGCATATGATTAGTCATTCTCATgaaaaaccgtttgcgtgtAGAAGTTGTGACTTTAAGTGCGCACGTAAGGTAAGTTTGAGAGGTCATTTTTTGAAAGTTCATACTGGTGACACAGAAtttgtttgtgaaatttgtTCTTTTAAATGTTTAACCAACGTAGGATTGAAACAGCATATGAGAACTCATCCAGAGTTTGGTTGTAAATTTTTCTGA
Protein Sequence
MEKAILIGEYLEVKEETEEEKKVNLQDLHHSIDIKEDQPSGSEVQIFHPFKSDLSNLKFTSQTQDRKYTKDQPATPKVFSCELCDYKCSMKGNLTTHIRTHTGEKPFTCSICDFCSARSTVLRDHLKVHTGEKPFPCDVCDYKGSTKLNLKRHMTTHNGEKPFSCDICDYTCSTNILKQHMRIHTGETLFSCEFCDYKCAMKGHLVTHVRTHTGEKPFNCAICDFKCARKASLKDHLKVHSGEKPFPCGICDYRSSNRLTLKRHMVTHTGEKPHMCTICDFKSAHKVSLKDHLKIHTGEKPFSCEKCVYKSSNKLALKRHMISHSHEKPFACRSCDFKCARKVSLRGHFLKVHTGDTEFVCEICSFKCLTNVGLKQHMRTHPEFGCKFF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01292617;
90% Identity
-
80% Identity
-