Basic Information

Gene Symbol
-
Assembly
GCA_958510855.1
Location
OY294038.1:17616225-17617622[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 3.6e-06 0.00024 22.3 1.9 1 23 42 64 42 64 0.98
2 13 1.5e-05 0.001 20.4 2.4 3 23 72 92 70 92 0.98
3 13 2.2e-08 1.5e-06 29.3 1.1 1 23 98 120 98 120 0.98
4 13 0.0004 0.026 15.9 0.2 1 23 126 148 126 148 0.98
5 13 3.2e-05 0.0021 19.4 0.7 1 23 154 176 154 176 0.98
6 13 8.2e-05 0.0055 18.1 1.6 3 23 229 249 227 249 0.96
7 13 3.7e-06 0.00025 22.3 2.1 1 23 255 277 255 277 0.98
8 13 6.4e-05 0.0043 18.4 4.4 1 23 283 305 283 305 0.98
9 13 0.0017 0.11 14.0 2.3 1 23 311 333 311 333 0.98
10 13 1.4e-05 0.00096 20.4 3.7 1 23 339 361 339 361 0.98
11 13 0.00023 0.015 16.7 1.0 1 23 367 389 367 389 0.98
12 13 0.00089 0.059 14.8 5.1 1 23 395 417 395 417 0.98
13 13 6.8e-06 0.00046 21.5 2.3 1 23 423 445 423 445 0.98

Sequence Information

Coding Sequence
ATGCCGAGCACCTCCCAAGAAGATTCTGTCGAAACTGCCATTGACTCTGATGACCCAAATGCTCTAATTGAAAAGATCAAAAAGTCGGTCAAGTATGAAGTTTCGGAATCGGGTGAGAAGAGTTACATTTGCACAATTTGTAATACAAAGTTTTCTAAGAAGAATACATTGGATAGACACATGAGAATACATACCGGCGAAAGGCCGTTTGGATGCGATATTTGTGGTAAAAAATTTCCCCGAAATTGTCAATTGTCGagtcatttaaaaacgcacaccggcgaaaaaccatttgtgtgtgaaatttgtggttgGAAGTTTTCACATAAATCTGGTTTGACAAACCACATAAGAACACACACGGGCGAGAAACCGTACGCATGCGAATTGTGTGGTGCTAAATTTCTAGAAAAGGGAACATTACAAAGGCACTTGAggactcacacaggagaaaagcCGTTTTCGTGCGAAATTTGCGGTTTGAAATTTTTACGGAAAGATTACCTACAAACGCATTTGCGAGTCCACGTGTCGAATACTTCGCAAACAGTAAATAAAGGTTGTGAAATAAAAATGGAAGTAACACCGGATGTGGGCTGCCAATTAGAAGAAaaagttggtaatttagaaAGAAATAGtgatttttacaaaatgaaaactaaaataGGAGGGAAGACGCATCTCTGTACGATTTGTAGCATAGAGTTTCCAAAGAAGAGTACCTTGGACCGACACATTCGAACgcatactggcgagaaaccatttCCATGCGAACAGTGCGGCATGCGATTCCCACGAAATTGCCAGCTCACGAGTCATTTGAGAACGCACACCGGCGAAAAATCGTTCGTCTGTGAGATATGCGGCGGAAAATTTTCACACAAGTGCACCTTGAACAACCACTTAAAAACGCATACGGGCGAAAAGCCGCACGTGTGCAAATCGTGCGGCTTGAAATTCTTGGAAAAGGGCACCTTACAAcgacatttaagaactcacacaggcgagaaaccttTCTCTTGCGAGCTGTGCGacaaaaagttttcacgaatttgTCAACTCAAGCGTCATTTAATAACGCATACGGGAAATAAACGCTTCGAGTGCAGCTTTTGTTCTCTGAAATTTGCGGAAAAGTCAAAGTTGGGAAATCACATTAGGAcccatacaggcgaaaaaccgtatCATTGTGATTTGTGCGATTATAAATGTTCAATTAAAGACAATTTGCGTAGTCACTTGAGAAGTCATACGGGAGAAAAGCCGTATGCTTGTGAAGTTTGTGATTACAAGTGTACATCTAAAGCTAATCTACGAAATCATTTGAAAACTCATCCCGGACAAAATCAACTCGCTGGTGAAGTGGTCGTTCGTAGAGTGAAAATTTACAAAGATTGA
Protein Sequence
MPSTSQEDSVETAIDSDDPNALIEKIKKSVKYEVSESGEKSYICTICNTKFSKKNTLDRHMRIHTGERPFGCDICGKKFPRNCQLSSHLKTHTGEKPFVCEICGWKFSHKSGLTNHIRTHTGEKPYACELCGAKFLEKGTLQRHLRTHTGEKPFSCEICGLKFLRKDYLQTHLRVHVSNTSQTVNKGCEIKMEVTPDVGCQLEEKVGNLERNSDFYKMKTKIGGKTHLCTICSIEFPKKSTLDRHIRTHTGEKPFPCEQCGMRFPRNCQLTSHLRTHTGEKSFVCEICGGKFSHKCTLNNHLKTHTGEKPHVCKSCGLKFLEKGTLQRHLRTHTGEKPFSCELCDKKFSRICQLKRHLITHTGNKRFECSFCSLKFAEKSKLGNHIRTHTGEKPYHCDLCDYKCSIKDNLRSHLRSHTGEKPYACEVCDYKCTSKANLRNHLKTHPGQNQLAGEVVVRRVKIYKD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-