Basic Information

Insect: Rhagonycha fulva
Gene Symbol: thap1
Assembly: GCA_905340355.1
Location: HG996557.1:32615784-32618842[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 1.1 32 6.1 1.7 2 23 254 275 253 275 0.95

2 11 0.0002 0.0056 17.9 1.9 1 23 279 301 279 301 0.98

3 11 0.0078 0.23 12.9 0.3 1 23 307 329 307 329 0.97

4 11 0.00067 0.019 16.2 4.9 1 23 335 357 335 357 0.98

5 11 0.0005 0.014 16.6 0.6 1 23 363 385 363 385 0.99

6 11 0.0023 0.065 14.6 3.4 1 23 391 413 391 413 0.97

7 11 5.6e-05 0.0016 19.6 0.5 1 23 419 441 419 441 0.98

8 11 0.0024 0.069 14.5 1.7 1 23 447 469 447 469 0.99

9 11 0.0026 0.074 14.4 0.7 1 23 475 497 475 497 0.97

10 11 0.034 0.99 10.8 6.5 1 23 503 525 503 525 0.98

11 11 1.2 35 5.9 0.4 1 23 630 651 630 652 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	1.1	32	6.1	1.7	2	23	254	275	253	275	0.95
2	11	0.0002	0.0056	17.9	1.9	1	23	279	301	279	301	0.98
3	11	0.0078	0.23	12.9	0.3	1	23	307	329	307	329	0.97
4	11	0.00067	0.019	16.2	4.9	1	23	335	357	335	357	0.98
5	11	0.0005	0.014	16.6	0.6	1	23	363	385	363	385	0.99
6	11	0.0023	0.065	14.6	3.4	1	23	391	413	391	413	0.97
7	11	5.6e-05	0.0016	19.6	0.5	1	23	419	441	419	441	0.98
8	11	0.0024	0.069	14.5	1.7	1	23	447	469	447	469	0.99
9	11	0.0026	0.074	14.4	0.7	1	23	475	497	475	497	0.97
10	11	0.034	0.99	10.8	6.5	1	23	503	525	503	525	0.98
11	11	1.2	35	5.9	0.4	1	23	630	651	630	652	0.95

Sequence Information

Coding Sequence: ATGGTGCAAACCTGTAGTGCTTATAACTGTAATGAACGACACAAACGTGGAACAGATGTATCATTTCATCTATTTCCACAAGATAAAACATTGCAAAACCAATGGATCTCGGCAATGCGTCGAGAAAAGTTCAAACCATCGAAACATACTAGAATTTGTTCCAAACATTTCACGCCAGATTCGTTTAGTACTAGCGCTTGGAGTTCGGTAAAAAAACTTAAAAATCATGCTGTACCAAGCGTTTTTGATTTTCCTGATCCTTTGGTGAAGAAAGTAAGAACTAGGAGACCTCGGGCATCAAAAAATCTTAATGTTGAAATACAAGATAACCTCAAAACAACAACAGATGATGAAAATAAGTCTGCCGATGAAATTAAAAATCAAGTTCAAGTTTTTATTAAGGAAGAACCTAACGAGGAAGAAAATTTTGTGAATTTGAACGCTGAAAATGAGATTGAAATTGTTAAAGAAGAGTTGCCAGATTTTGAGTACGAAGATGAAACAAATATGGAAATGGAACATAACGTAAAAAATGAAATAACGATTAAGGATGAACTGTTGGAGGGTATATCTGACGAGTTAGAAATTCCTGGGAGCACCTCCAACCATTGCATGACTACAATGGGAATGGAATGCTTGAATAACAATTTGGAGAATTTACCTCACTCAAACAATGTTACAGATAATACAACAGTAGAATATCCAGTTAATACTGAAAAGGAAAACGAACTTGATAGGATTAGCAAAGAATCAAATCTTTCCTGTGACATTTGCAATTTTACATGCCAAAATGAAACTTCATATTACTTGCACTTGAGTATTCATAAAAAGTCTTTTATCTGCCCTCTATGCGATTTTAAAACCACACATAAAAATGCACTAAAAGTCCACTTGAGAACTCACACCGGCGAGAAACCGTACGCCTGTAGGCTTTGTGATTTTAAAAGTGCCTATAACAGTGCTCTACAAATTCACCAGAAAATACACACCGGGGAAAAGCCACACGTCTGTGAATTCTGTGGTTTTAAGTGCATACAGAAGAGAAATCTGGAAAATCATCTACGGACTCACACCGGTGAAAGACCCTACGTCTGCGACGTTTGCGATTTTAAAAGCACACGTAACGACGTTTTACAAAATCACCTGAAAACTCATTCTACAGAAAGACCCTTTGCATGCCTAGTGTGCAATTTTAGGAGTTCACGCAAGCACTACCTACAAAAACACTTGCGGGTGCACACCGGTGAGAAGCCATATGCGTGTGAAATTTGTGACTACAAGAGCGGAACAAAAAGTAATTTACAAAGTCACCAAAAAATTCACACGACCGAGAAACCATACACCTGCAATTTATGCGAGTTCAGAAGCGCACACAAAAACGCATTACAAATTCACATCAAAACTCACTCCACCGAAAAGCCATTTGCATGCGAACTCTGCGATTTTAAAAGCACACGTAATGACGTTCTACAAAATCACTTGAAGACGCACACCGGTGAAAAACCCTTTTCATGCCACAGTTGCAGTTTTAAAACAGCACACAAATACCTCCTACAGAGGCATATAAAAATGCATTGCGGTAAAATTGTATACTCATGCAAATCTTGTGACTTTAAATCTGACAAGCGGAAAATTCACCAAGGCCACTTAAAAACCCACCTTTCAAAAAAACAATACTTCTGTGGAACATGTGATTTTGAAAGTGATCGTTTTGAAGTTTTTGAAATTCACTGGAAGAATCACTCGTCTAAATCTAAAAGTACTTTGGGTGATTTAAATGAACCCTACGTTTTAAAAAAGCGGTTTTTCTGCGATCTGTGCGAGTATGAAAGTGATCATCTCAAAGTTTTTGAAACTCACTGGAAAAAGCATGCAGTCGATAATACTTACTCTTGTGACACCTGTGATTTTAAAAGCGCTTTGGGTGATTTACAAAACCATTTAAAAAGTCACATGCATTCGTAA
Protein Sequence: MVQTCSAYNCNERHKRGTDVSFHLFPQDKTLQNQWISAMRREKFKPSKHTRICSKHFTPDSFSTSAWSSVKKLKNHAVPSVFDFPDPLVKKVRTRRPRASKNLNVEIQDNLKTTTDDENKSADEIKNQVQVFIKEEPNEEENFVNLNAENEIEIVKEELPDFEYEDETNMEMEHNVKNEITIKDELLEGISDELEIPGSTSNHCMTTMGMECLNNNLENLPHSNNVTDNTTVEYPVNTEKENELDRISKESNLSCDICNFTCQNETSYYLHLSIHKKSFICPLCDFKTTHKNALKVHLRTHTGEKPYACRLCDFKSAYNSALQIHQKIHTGEKPHVCEFCGFKCIQKRNLENHLRTHTGERPYVCDVCDFKSTRNDVLQNHLKTHSTERPFACLVCNFRSSRKHYLQKHLRVHTGEKPYACEICDYKSGTKSNLQSHQKIHTTEKPYTCNLCEFRSAHKNALQIHIKTHSTEKPFACELCDFKSTRNDVLQNHLKTHTGEKPFSCHSCSFKTAHKYLLQRHIKMHCGKIVYSCKSCDFKSDKRKIHQGHLKTHLSKKQYFCGTCDFESDRFEVFEIHWKNHSSKSKSTLGDLNEPYVLKKRFFCDLCEYESDHLKVFETHWKKHAVDNTYSCDTCDFKSALGDLQNHLKSHMHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01291629;
90% Identity: iTF_01291629;
80% Identity: iTF_01291629;