Basic Information

Gene Symbol
-
Assembly
GCA_963680705.1
Location
OY796658.1:84186352-84188766[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 2.2e-05 0.0025 20.0 3.6 1 23 158 180 158 180 0.99
2 11 6.1e-05 0.0069 18.6 5.0 1 23 186 208 186 208 0.99
3 11 0.016 1.9 10.9 4.0 1 23 216 238 216 238 0.96
4 11 0.0001 0.012 17.9 1.5 1 23 244 266 244 266 0.98
5 11 0.00014 0.016 17.5 1.5 1 23 275 297 275 297 0.97
6 11 2.1e-05 0.0024 20.0 1.0 1 23 303 325 303 325 0.96
7 11 1.7e-07 1.9e-05 26.6 1.2 1 23 331 353 331 353 0.98
8 11 6.7e-07 7.6e-05 24.7 1.9 1 23 359 381 359 381 0.99
9 11 0.00023 0.026 16.8 0.5 3 23 389 409 388 409 0.99
10 11 0.00016 0.018 17.3 1.0 1 23 415 437 415 437 0.98
11 11 6e-07 6.9e-05 24.9 0.3 1 23 443 465 443 465 0.97

Sequence Information

Coding Sequence
ATggaaacaaactacaacaaactTTGTCGAATATGTTTAAAGGAATCTGATAACATGGAAGAACTATATACATTTACATTATCTAAAGAAGATATCCGTGCAGTAGATTTCATAAGAAAAATCACAGATTTAAAGCTTGCACATTCAGCTACTTTACCAAAGAACTTGTGCAATAAATGTGTACAGAATACCACAGCAGCTTTTGACTTTGCTCAGTTATGTATTGCTTCAGATGCTTCGTTAAGAAACCAAGAAACACGTCGAATGTTAAGGAAAATTGAAGAGGAAGCGTTGGGTGAGGAAGAAATAGTTATAAAGTGTGAGGTACTCAATGAGAATGAAAACGTGGATATACCACAAAGTGATCAGTTTGATGTTGATGAAATATCTGATGACAATTCAAGTGAAAATGAGATAGCTCCACCTACAACTACAGATTTTAATGTACCAACCGTAAAATCTAAAGATAAATATAAATGTGACGTATGTTCTCTGTCATTCAACAATAAGACTAAATTTCAGAAGCATCAAAACACGCATGACGATACTAAACCTTTCAAATGCAAGGAATGTTCACAgtctttttccaaaaaactgCATTTAAATCTACATTTAAGGTCGCATATTAAGCAAGAAGATAAGAAATTTTCATGTAAAAAGTGTAGTCAACAATttacttttgaatatttattaaagcaacatgaatacaaacacACCGATGAAAAACCATTTCCGTGTACAAAATGTGataaagggTGTTTGACGGCTGAAAGTTTGAGAAGACATATGAGAATTCACGAAGAAACCTACACCAAAAAAACGCATACCTGTTTGATTTGCAAGAAAAACTTTCCATATCCTAGTTTTCTGGCTGAACATATGAAAAACCACACCGGAGAAAAACCATACTTATGTTCAATTTGTGGCAAAGGCTTCCGACAGACTGGAGCACTGCATTACCATCAAAGAATACATACTGGTTATAAACCATTTCCTTGTAAAATAtgtgacaaaaattttagaTCACAGAGTGTTTTGAGGGTTCATATGAGAAAACATACCAATGAAAGACCTTACGTGTGTGATATTTGTGGAATGTCGTTCCGACAGTTAACAGATTTAAAGTCTCATCACCGAACCCACACAGGTGAAAAGCCTGTACTATGTACAATATGTGGAAAGAAAATGTCTACTACGGGGCAATTAACTGTTCACATAAGATCCCACACAGGTGAAAAGCCGTATTCCTGTTCGGTTTGTTCCAGATCCTTTACCACTAAAACAGTATTGGGGAAACATGAGAGAATTCACACAGGAGAGAGACCCTATGTATGTGACATCTGTGGTAAAGCTTTCAATCAAAGCTCGACTCTAAGAACTCATTCGGCAACTCACAaagtaaatagtaataaaaaaaagaaaaaaatcaagaGTCTAGCGAAAAATGCAAGACGAGAGATACATCTAGAAAATAACGCAGTTGTGCTATATAAAAATGAGAATGGAGTTACCGAGGCTGTTAATGAGCAATATCTTGTAGATAACGTGGTGGAAATAAGTGATGAACAATGTGAAAATGTTAAAGCTGAGTTTACTGTTATTTTACCGGCTCCTATACCATTGTTACAAAACATGTAA
Protein Sequence
METNYNKLCRICLKESDNMEELYTFTLSKEDIRAVDFIRKITDLKLAHSATLPKNLCNKCVQNTTAAFDFAQLCIASDASLRNQETRRMLRKIEEEALGEEEIVIKCEVLNENENVDIPQSDQFDVDEISDDNSSENEIAPPTTTDFNVPTVKSKDKYKCDVCSLSFNNKTKFQKHQNTHDDTKPFKCKECSQSFSKKLHLNLHLRSHIKQEDKKFSCKKCSQQFTFEYLLKQHEYKHTDEKPFPCTKCDKGCLTAESLRRHMRIHEETYTKKTHTCLICKKNFPYPSFLAEHMKNHTGEKPYLCSICGKGFRQTGALHYHQRIHTGYKPFPCKICDKNFRSQSVLRVHMRKHTNERPYVCDICGMSFRQLTDLKSHHRTHTGEKPVLCTICGKKMSTTGQLTVHIRSHTGEKPYSCSVCSRSFTTKTVLGKHERIHTGERPYVCDICGKAFNQSSTLRTHSATHKVNSNKKKKKIKSLAKNARREIHLENNAVVLYKNENGVTEAVNEQYLVDNVVEISDEQCENVKAEFTVILPAPIPLLQNM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01296715;
90% Identity
iTF_00886717;
80% Identity
-