Basic Information

Insect: Rhagium mordax
Gene Symbol: ZEB2
Assembly: GCA_963680705.1
Location: OY796659.1:66724538-66730391[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00069 0.079 15.3 0.3 3 22 164 183 162 183 0.94

2 14 5.7e-05 0.0065 18.7 3.9 1 23 192 214 192 214 0.99

3 14 0.035 4 9.9 2.3 1 19 220 238 220 243 0.96

4 14 1.8e-05 0.002 20.3 0.6 1 23 249 271 249 271 0.98

5 14 0.00017 0.019 17.2 3.0 1 23 277 299 277 299 0.93

6 14 2.1e-05 0.0024 20.0 0.3 2 23 313 334 313 334 0.97

7 14 0.0021 0.23 13.8 1.1 1 23 340 362 340 362 0.96

8 14 0.013 1.5 11.2 2.2 1 23 394 416 394 416 0.95

9 14 6.9e-06 0.00079 21.5 1.0 2 23 429 450 428 450 0.97

10 14 9.2e-05 0.01 18.0 1.2 1 23 456 478 456 478 0.95

11 14 4e-06 0.00046 22.3 2.9 1 23 484 506 484 506 0.97

12 14 0.00037 0.042 16.1 5.6 1 23 512 534 512 534 0.98

13 14 2.2e-05 0.0025 20.0 2.9 1 23 540 562 540 562 0.99

14 14 0.00051 0.058 15.7 3.9 1 23 568 590 568 590 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00069	0.079	15.3	0.3	3	22	164	183	162	183	0.94
2	14	5.7e-05	0.0065	18.7	3.9	1	23	192	214	192	214	0.99
3	14	0.035	4	9.9	2.3	1	19	220	238	220	243	0.96
4	14	1.8e-05	0.002	20.3	0.6	1	23	249	271	249	271	0.98
5	14	0.00017	0.019	17.2	3.0	1	23	277	299	277	299	0.93
6	14	2.1e-05	0.0024	20.0	0.3	2	23	313	334	313	334	0.97
7	14	0.0021	0.23	13.8	1.1	1	23	340	362	340	362	0.96
8	14	0.013	1.5	11.2	2.2	1	23	394	416	394	416	0.95
9	14	6.9e-06	0.00079	21.5	1.0	2	23	429	450	428	450	0.97
10	14	9.2e-05	0.01	18.0	1.2	1	23	456	478	456	478	0.95
11	14	4e-06	0.00046	22.3	2.9	1	23	484	506	484	506	0.97
12	14	0.00037	0.042	16.1	5.6	1	23	512	534	512	534	0.98
13	14	2.2e-05	0.0025	20.0	2.9	1	23	540	562	540	562	0.99
14	14	0.00051	0.058	15.7	3.9	1	23	568	590	568	590	0.99

Sequence Information

Coding Sequence: ATGGATTACAAAGATGTGAATATTAACATAATTTATGAAGACTTTCCAGATATTTGTCGTATATGTCTAGAGAAAGAGAAATCTTTAAAACCTTTTGGGCAGTTAGGTTTATTGGAtacattcaaaaatataactaacATTGAGATTGAATTGGATGAcaatttaccaaaaaatatatgtattaggTGCAGTAACAAATTGGAAGATATATcctcttttattaatttatgtaaaagTAGTCATGCAAATCTCAAAGATATTGTTCAGAAAACAAAAACTGAGTCATATTTGGAAGATATTATCTCTGAGTTTGTAGTAGACGATTCAATTGAGCATTCATGTGATATTAAAGAGGAAGGTGTAAACATTTTACACAGTGATTATACTGCAGGCCTTAGAGAAGTAGAAACATTTGATGTTCCAACTTCGGTTGACACGGAGGATGCTAAGAAGTTATTAAGACATTCCACCAAGAGACAACCTTCAAATTGTGATATATGTGgtgaaaattttataacaaaacgTAAACTGATTGAGCACCAAAAAAAGAACGATAATTGTAGAACTAGACGATATAAATGTACGAATTGTGAAAAGGCTTTCTTTACAAAATTCAGACTAAAATTGCATATGAGGTCACATACTAAAGAAACACCATACGAATGTAAAGTTTGTTGtaaaaaatttagatttgcTCCAAACTTGAAAAGACACGATGATGTTGTTCATAAAGGTCTGAAACCATTCAAGTGTGATATATGTGGAAAAGAATTTTCAAGATTAGATAGAAAAACTGTACATATGAATATACATACTGGAGAACATCCACACATTTGTGATTATTGTGGAAAAGCCTTTATACACAGATCTACTTACCGCAACCATGTAACTGATCATAAAATAGCAAATGGAGAAATTCAAGATCTCTCGgaaagaaaatgtgaaatttgtgCTAAAGTATTTTCTTCCAAGCAATCTCTTCAATCACATATAGAAATTCATATAGGGGAGAAAAGATTTTTATGCCCAATATGTGGAAAagattttttatacaaatgttATTTAGACAATCATATAAGGGTTCATACTGGAGAAAAGCCATTTGACTGTAAAGTTTGTGaaTTTGCAAGACATACCAATTTAGTAGAACATGAAAGAGATCATTCCGGGGAAATTCCATTTATTTGTAACTATTGTGGGTTGTCATTTAAGAAGACAGGTCCATACCATTATCATTTAAATCTACATAGGGCCTCAAATTCAGAAAGTAATAGTGAGGACTTAACCTGCAATGTCTGTGGCAAAATATTTGGTTCAAAAACGACACTTAAAAAGCACAGAATTACTCATACTAAAGAAAACAGCTTTTTATGTGATATATGTGGCAAACATTTTAGCACAAAACAGATTTTAGAAAACCACATTAAGGTACATTTGGGAGTGAGGCCCTTTAAGTgtgaattttgtgaaaaaagtTTCTCTAGGAAATCCACATTACAAGTTCATACCCTATATCACACTAAAGAAAAACCTTTTAAATGCAAAACCTGCTTGAAAACTTTTGCACAACATGTTCATTTAAGAAACCATGAACGTATCCATAATGGTGAAAAACCATATAAGTGCGCATACTGTAATAGGACGTTTTCTGTTAAATGTAATTTAGTAATTCATACACGAATACATACGAATGATACTACATATAAATGCACTGTTTGTGAAAAACTATGTTATGAATCAAGgagtttaaaaaaacatatgaGAGTACATCAAGACTCATCGCTAATTGTACTAACTAATGAAGATATTACCACATTattatcataa
Protein Sequence: MDYKDVNINIIYEDFPDICRICLEKEKSLKPFGQLGLLDTFKNITNIEIELDDNLPKNICIRCSNKLEDISSFINLCKSSHANLKDIVQKTKTESYLEDIISEFVVDDSIEHSCDIKEEGVNILHSDYTAGLREVETFDVPTSVDTEDAKKLLRHSTKRQPSNCDICGENFITKRKLIEHQKKNDNCRTRRYKCTNCEKAFFTKFRLKLHMRSHTKETPYECKVCCKKFRFAPNLKRHDDVVHKGLKPFKCDICGKEFSRLDRKTVHMNIHTGEHPHICDYCGKAFIHRSTYRNHVTDHKIANGEIQDLSERKCEICAKVFSSKQSLQSHIEIHIGEKRFLCPICGKDFLYKCYLDNHIRVHTGEKPFDCKVCEFARHTNLVEHERDHSGEIPFICNYCGLSFKKTGPYHYHLNLHRASNSESNSEDLTCNVCGKIFGSKTTLKKHRITHTKENSFLCDICGKHFSTKQILENHIKVHLGVRPFKCEFCEKSFSRKSTLQVHTLYHTKEKPFKCKTCLKTFAQHVHLRNHERIHNGEKPYKCAYCNRTFSVKCNLVIHTRIHTNDTTYKCTVCEKLCYESRSLKKHMRVHQDSSLIVLTNEDITTLLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -