Basic Information

Insect: Reticulitermes lucifugus
Gene Symbol: Zfhx4
Assembly: GCA_026260175.1
Location: JAKCWW010001457.1:2599-6348[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 8.6e-05 0.0086 17.2 2.5 1 23 417 439 417 439 0.99

2 4 0.00038 0.037 15.2 0.3 1 23 557 579 557 579 0.98

3 4 0.0081 0.8 11.0 0.2 2 23 737 759 736 759 0.96

4 4 0.31 31 6.0 3.4 2 23 1058 1081 1058 1081 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	8.6e-05	0.0086	17.2	2.5	1	23	417	439	417	439	0.99
2	4	0.00038	0.037	15.2	0.3	1	23	557	579	557	579	0.98
3	4	0.0081	0.8	11.0	0.2	2	23	737	759	736	759	0.96
4	4	0.31	31	6.0	3.4	2	23	1058	1081	1058	1081	0.89

Sequence Information

Coding Sequence: ATGGCCAGTCAGAGCGGATTGCCACCCAAAGTCATTAAGCACTGGTTCAGAAACACTTTATTTAAAGAGAGACAGCGGAACAAAGACTCGCCTTACAACTTCAACAACCCCCCGTCAACAACTCTTAATTTAGAAGAATACGAAAAGACGGGGGAGGCCAAAGTTTTGCCACTTAATAGCAGTGGCAGCGGGAACGAGGATCAGCACGCTGCGATCAAAGAGGCAACACCCACGAGACCACCTTCGGTAACAACGGCTTCGTCGTCAAGCAAGAGGAAGCAATCGCAGCCCCAGCCATTTCCGCCTCCACATGCATTTCCGCAACACGCAGAAATGATAAAGACGGAACCACGAGATATCTCACTCCATCACCTAGACAATCAGGACCACAAATTCAACAACCTGTTCATGGAGCCCGAGCATGGTAGCAACAACAAGAAAGAAGGAGACGGTGAAAGGTTCTTAGATCTCGCAGACGAGAAGCCTCCTCACGGCCTGTACCCACCGCCTAGCCCTGTGACAACGATGGCGAGTAACAGCAGTAAGAACATTAACAACAACGACAATTCAAGTTCTGTTCCTCCATCAAGCATTGTAAGAAGTTCCTCTCCGAGTAACCTTACTTTGACTTCAATTATAGCGTCGCAGTTAGGCTCAGACGCCATCACAACGACTCATCCAACAATGAACGCAACTAACGTAACAGTGACGTCATCCTCACATTCCAATAACGGCACCTCCAGCAACATGTTGCCTCCAAAATTGACACCTCCAAACTTTCCACCGCCTAATCAAGTTCCTACGTCGCCCGGAATACTACCGCCTCTCGCATCATCTGCCACTGCTGTCTCGAGAAGTGTCAGTCCCGGTCGATCATACAGCAGCAATTCTTCTGATGGCTTTGGACACACGTCGCTGTCTTCGGGAGGATGTGGCGCTGGTAGCGGTAATAGTAACGGAAGTAATTCTTCTGGAGGTTCTTCTGGTAAAAGAGCAAATCGGACACGATTTACTGATTATCAAATTAAAGTTTTGCAGGAATTTTTTGAAAACAATGCGTACCCAAAGGATGATGATTTGGAGTATTTATCAAAGCTCTTAAGTTTGAGTCCAAGGGTCATAGTTGTGTGGTTTCAAAATGCGCGCCAGAAAGCACGTAAAGTATATGAAAACCAGCCACCAGTTGAAGCACCCCCAGGCGTGGATGAAGGGGGCGCGAATAGATTTCAAAGAACACCTGGCTTAAACTATCAATGTAAGAAATGCCTGCTTGTGTTCCAACGCTACTATGAGCTTATACGACATCAGAAAACCCACTGCTTTAAGGAAGAAGACGCTAAGAGATCTGCTCAGGCCCAGGCTGCAGCAGCTCAAATAGCTGCCGTACTGTCGTCTGAGGATTCAaactccagtactatagcagaacctagtcagcaacaacagcaacaaccaccacaaccacaacaacagcaacaacaacaacaacaacaacaacaacaacattgtcttcagcagcaaccgtctatggtatcagtgacttcgtcaacatccagcaaccccgccactccttcagcagctgtaacacccacgccaccatcatcCTTGTTTCCACAGTCACCAGTCTCTGGAACACAAAGTAACACTGACAGCACTGTCAAGGAAGGAACTTTCCAGTGTGATAAGTGCAATTTAGTGTTCCCACGATTCGATCTCTGGAGAGAGCATCAACTTGTGCATATTATGAACCCAAATTTGTTTCCTACTTATCCGCCAGATAGCccattcggaattcttcaacagcatgcgcaaatacaacagcagcaacagcaacaacaacaacagcagcaacagcaactgagtggaatgggtgtagcagatttgtcggttaactCTACATCGGCTTCCCCTCATTCGCATCCTCTAGTAGCTGTTCTGTCTAACAGACGGAAATTTGACGATTTTGAAGACGCTTTAGACCGAGATTGTGATCAACCAAAAGATAAGAGACTGAGGACGACAATTCTGCCGGAGCAACTAGACTACTTGTATCAAAAATACCAACTGGAGAGTAACCCATCGCGCAAGATGTTGGAGAACATAGCGCGAGAGGTCGGACTGAAGAAGCGCGTCGTGCAGGTGTGGTTTCAAAATACACGGGCGCGTGAGCGTAAGGGGCAATTTCGAGCTCATGCCCAAGTAATTAACAAGCGATGCCCGTTTTGCCCAGCACTGTTCAAAGTGAAATCTGCCCTGGAGTCACACCTGGTAACTAAGCACGCTGATCAGTGCACACGCGGTGAGATTAACATCGACAGCCTGCCAGACGAGGAACTGAGCATGGAGTCTGCTCCTTCTTCTCACATGGGCGACAGTGGCAAAGTCGCCACGAACTTCGGTTCCGCGACTCAGACGCCTAATATGATGCCTCCACTTTTCCCAACTTTCCATTCAGACATGGAAAATTCTCTGAAGAAATATTATGAAGAATCTATGAAACGTTACATTAGCGAACTTCAAGCCCATCACGTCGCTCAGAATGGCGGTATCAATAAGGAGGGCTTACACATCCCTACAGATCTGAGCATGAAGATTAAACAAGAACCTTCAACTCCTGGTAGTGAAGCGAGTGGTAACGCAAGTGGAAATGGTGGCGGTGGAGTCGGTGACGGACCTCTTGATCTCAGCAAACCTGTGGACTTGAGCCGCCCCGTTAAAGTTTCATTAGATCATGACTCGCGGTCCATGATGGCCGAACCCGGGCCCCTCACAGATTTAAGTGAGCGCAGCTTGTGTTATGAAGACGATAGCATGTCAGAAACGACGGAGAACATGGACGGCGATGAAAGCAACCCGACGTCGCCGGCGTCCAGCACACAGAGCAGCCATCAGCGTCCTGTTCCGTCTGGTGGCGGGAAGAGGTTCCGTACACAGATGAGCAGCATTCAAGTAAAGGCGATGAAATCTTTATTCAACGACTATAAAACTCCGACTATGGCAGAATGTGAGATGTTAGGCCGTGAGATTGGTTTACCAAAAAGAGTGGTCCAAGTATGGTTTCAAAATGCCCGAGCTAAAGAGAAGAAAAATAAAATAGCGCTCCAGAAAGCATTGGGTGGTTCAGAAACGTCTCCTTCCGTGGTCACGACATCTGATTCATCTCGACCACCAGAAGAATGTAAGCTCTGTCAGTTCAGGTACTCACACAAGTACTCCATTCAAGATCATATCTTCACGAAAAAGCATATTGATAACGTGAAGGCTCACATCGAGAACGGGAAGGCAGATACTTCTGGAAACACGAGCGACGGGGGTGGTAGTGGCTCCGGAGCGGGGGAATTCACTGTGCCCCCGGTGCCTGGTTCATCTGGAGGTACCGGAGGGACTGACAACACATCGGTTCCTACTCAGTCATCTCCTCAGTTCCTGAACAACAGCGTAGCAGCCGCTGCGGCCCAACAACAGCAACTCGCACAGCTACAGATGCTGCAGATGGCCGCCGCTTCTGGTCTTGCGCTTCCAAACTCATTGTCAGCTCAAGCGCAGGCGATGGCGGCTGCAGCGGCAGCAGCAGCAGCTGTCAGCTCCACCAAGGATCAGCACGGAGGCTCCAAGTCACCAACTCCTAGCCCAGACGACATGGCACTGTTGCATCAGCTGTACGGCCTGGGGCTCGCCGGCTTCCCTGGCGCCATGCAGGCTGGCAATCTGTTCCTGCACCCAGCAATGTTCTCTGCTGCAGCCGGTGAGTAG
Protein Sequence: MASQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVLPLNSSGSGNEDQHAAIKEATPTRPPSVTTASSSSKRKQSQPQPFPPPHAFPQHAEMIKTEPRDISLHHLDNQDHKFNNLFMEPEHGSNNKKEGDGERFLDLADEKPPHGLYPPPSPVTTMASNSSKNINNNDNSSSVPPSSIVRSSSPSNLTLTSIIASQLGSDAITTTHPTMNATNVTVTSSSHSNNGTSSNMLPPKLTPPNFPPPNQVPTSPGILPPLASSATAVSRSVSPGRSYSSNSSDGFGHTSLSSGGCGAGSGNSNGSNSSGGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLSLSPRVIVVWFQNARQKARKVYENQPPVEAPPGVDEGGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTIAEPSQQQQQQPPQPQQQQQQQQQQQQQHCLQQQPSMVSVTSSTSSNPATPSAAVTPTPPSSLFPQSPVSGTQSNTDSTVKEGTFQCDKCNLVFPRFDLWREHQLVHIMNPNLFPTYPPDSPFGILQQHAQIQQQQQQQQQQQQQQLSGMGVADLSVNSTSASPHSHPLVAVLSNRRKFDDFEDALDRDCDQPKDKRLRTTILPEQLDYLYQKYQLESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLVTKHADQCTRGEINIDSLPDEELSMESAPSSHMGDSGKVATNFGSATQTPNMMPPLFPTFHSDMENSLKKYYEESMKRYISELQAHHVAQNGGINKEGLHIPTDLSMKIKQEPSTPGSEASGNASGNGGGGVGDGPLDLSKPVDLSRPVKVSLDHDSRSMMAEPGPLTDLSERSLCYEDDSMSETTENMDGDESNPTSPASSTQSSHQRPVPSGGGKRFRTQMSSIQVKAMKSLFNDYKTPTMAECEMLGREIGLPKRVVQVWFQNARAKEKKNKIALQKALGGSETSPSVVTTSDSSRPPEECKLCQFRYSHKYSIQDHIFTKKHIDNVKAHIENGKADTSGNTSDGGGSGSGAGEFTVPPVPGSSGGTGGTDNTSVPTQSSPQFLNNSVAAAAAQQQQLAQLQMLQMAAASGLALPNSLSAQAQAMAAAAAAAAAVSSTKDQHGGSKSPTPSPDDMALLHQLYGLGLAGFPGAMQAGNLFLHPAMFSAAAGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01288829;
90% Identity: iTF_01288829;
80% Identity: iTF_01288829;