Basic Information

Insect: Quadriops clusia
Gene Symbol: topi
Assembly: GCA_033557875.1
Location: JAWQRP010000238.1:22293-25163[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00082 0.068 14.5 1.4 2 21 129 148 128 149 0.94

2 14 7.3e-07 6e-05 24.1 0.7 1 23 174 196 174 196 0.97

3 14 0.068 5.6 8.5 3.9 2 23 203 224 203 224 0.95

4 14 0.95 78 4.9 0.3 2 14 243 255 242 260 0.88

5 14 4.1e-05 0.0034 18.6 1.5 2 23 329 350 328 350 0.97

6 14 2.4 2e+02 3.6 0.2 1 21 356 376 356 377 0.88

7 14 0.13 10 7.6 2.7 2 21 393 412 392 416 0.83

8 14 0.12 9.7 7.7 0.4 1 23 548 571 548 571 0.97

9 14 0.0079 0.65 11.4 0.2 1 23 575 597 575 597 0.97

10 14 1.6e-05 0.0014 19.9 5.4 1 23 603 625 603 625 0.98

11 14 0.033 2.7 9.5 0.2 1 23 631 656 631 656 0.96

12 14 0.17 14 7.3 2.9 1 23 662 684 662 684 0.86

13 14 2.2e-05 0.0018 19.5 0.5 3 23 692 712 690 712 0.98

14 14 5.5e-06 0.00045 21.4 0.7 1 23 718 741 718 741 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00082	0.068	14.5	1.4	2	21	129	148	128	149	0.94
2	14	7.3e-07	6e-05	24.1	0.7	1	23	174	196	174	196	0.97
3	14	0.068	5.6	8.5	3.9	2	23	203	224	203	224	0.95
4	14	0.95	78	4.9	0.3	2	14	243	255	242	260	0.88
5	14	4.1e-05	0.0034	18.6	1.5	2	23	329	350	328	350	0.97
6	14	2.4	2e+02	3.6	0.2	1	21	356	376	356	377	0.88
7	14	0.13	10	7.6	2.7	2	21	393	412	392	416	0.83
8	14	0.12	9.7	7.7	0.4	1	23	548	571	548	571	0.97
9	14	0.0079	0.65	11.4	0.2	1	23	575	597	575	597	0.97
10	14	1.6e-05	0.0014	19.9	5.4	1	23	603	625	603	625	0.98
11	14	0.033	2.7	9.5	0.2	1	23	631	656	631	656	0.96
12	14	0.17	14	7.3	2.9	1	23	662	684	662	684	0.86
13	14	2.2e-05	0.0018	19.5	0.5	3	23	692	712	690	712	0.98
14	14	5.5e-06	0.00045	21.4	0.7	1	23	718	741	718	741	0.98

Sequence Information

Coding Sequence: ATGAATAATCTAGATATAGGAACCCTGAAATTGCATAGAGTGGATGCAATAGATGGAAGTGTAAGTTCAATTCAATACGATATTGATAACATCACGAATCAACTTATATCAACTTATCCAATAAATTCTGATCCTTCCTCATTTGGAACTGCTTTAGATCTATCTTTAAATGGTGGAGATAAAATCAGTTTCACATATAGCTATCTAGATTTGGATGATTCTTCTTTGAGAGTTATTAAATTAGGTGGAGTAGATGATATGAATGGTATGAATTTTTCAACTGAATTAACTTCACTCTTGAATGACTCTGGTGAATGTAAATCTATTGGACCTGCAACACATATCAAAAGGGAATCAAAAGTGCCCAATATACCCACCATGATTGTATGTCAGAATTGCGATACAAACTTTCccacaaaatatcaatatcaaCGCCACCAGTGCGAATTTAACGCCGAAAAAGTAGTTTTGAAACCAAATGCCGATATCAAAGACATCGACAAAGGCCTTCGAATGAAATTCGACTGTCCCACTTGCGGAAAGCAATTTGTTAGTCAAAATAACTTGGAAAGGCATCAGACAAGTCATGACGAAACAAATGTGAATGTTTGCGAGCATTGCAGTAAACATTTTGTCAGTGAAAACCGTTTGAGGATACACAAAGAGAATCACTGCAAGAAAGCCGGTGATATTTCCAAATTCTACAGAAGCGACGTTGCCGTATGGAAATGCTTAAAATGCAATCAAGTTTTTGCCACACCGGCATCAGCAAACTGTCATGCTGAAGTTTGTCCAGAGCCTCTAGAAactaaatttgaaaacaaatccAATCTAGAGAACTCTCAAGAAACTGACGAATTACACCTTTTAAAtgaggaaattaaaaatttatcgcATGTTGCACCAGAAATAGTGAACAACGAAGCGAATTTGAACAACATTTCCATCAAAAATGTCGAAAAAGTGTTAACAGAACTTTTACTTCAATGTGAATATTGTAATCGCACTTACgctgataaaaaatatctccTCCTCCATCAGAAGAAACATACCACTGAAATCAATTATGAATGCATCACTTGCAAGGAAACGTTCGATTCTTATACCCTTGCCACAAAGCACTGGTTAACAAAGTGCTCCGATGAagcaaatttgttttatttacccAAAATGACCTATTGCGAATACTGCGATCGTACTTTCAAATCtcatgaaattttgtacactcacaaaattaaaaagaagcaTTACACTCCAAAAACCTTCGTTTGCTCTGACGAACCTGTGGTCCCAGATGAGAAAGACACTAACGAAAAAGGAAACGAAAGCAAAGACTCTATAGTTAAATTAATCGAGTACGTCTtgtcagaaataaaaattccggataaccaattaaaagaaaaaaccgACTTTAATGGGGACAATTCGGAAGAAAAAGGGATTGAGAAAGTTGCAGACGAAAATGCTGTTGCAATTTCTGATATAAAAATGGAAGTGATGAGCGAGACAAGTAGCAAATCAGATCTAAACTCGCAAGAACTAGCCGAAACAGAGAAGAAAAAGAGGGGTCGGAAGAGAAAGTGGCCTAAGCAAACAACAAAAGCCAAACGTTTGGCTGCTACTGTTGAGCGAGGATTCAAGTATCAGTGCGAAcgttgcaataaaatatgggACAGTGTTGTTGACTTAGAACATCACCGGGAAACTGAGCATCCTGCCAACTTTAAATGTGAAGAATGTGATCaaGTTGTTCATAGTGCTAAAGCTTTATTAATCCATAGTAGAGCTCATCAAAGCTTAAAACCATATGtttgtgaaatttgtaaaCGGTGTTACTCACAAACATCTCATCTGTGGCAGCACATGAGGTTCCATCAAGGAATTAAACCTTTTGCATGTCCTCATGAGGGGTGTGAAGCTCGATATACTATACGCCCAGACTTGAAGGATCATATTAGAAAAGTTCATACTCGTGAAAGACCATTCAAGTGTTCCGTATGCGACAAGTGTTTCCTGACAGGCTCCGTATACTACCAGCATCGATTAATTCACACAAATGATCGTCGTTATGGATGTGACATTTGTCAAAAAAGATTTTTCCGAGCTGATGCCTTGAATAATCACCGTAGAATTCACACCGACGAAAGACCTTATCCCTGTGACATTTGTGGGCGCCAGTTTAGGCAAAAAGGCGACCGAAACAAACACGTCCGAACCCAGCATCCTTCCTAA
Protein Sequence: MNNLDIGTLKLHRVDAIDGSVSSIQYDIDNITNQLISTYPINSDPSSFGTALDLSLNGGDKISFTYSYLDLDDSSLRVIKLGGVDDMNGMNFSTELTSLLNDSGECKSIGPATHIKRESKVPNIPTMIVCQNCDTNFPTKYQYQRHQCEFNAEKVVLKPNADIKDIDKGLRMKFDCPTCGKQFVSQNNLERHQTSHDETNVNVCEHCSKHFVSENRLRIHKENHCKKAGDISKFYRSDVAVWKCLKCNQVFATPASANCHAEVCPEPLETKFENKSNLENSQETDELHLLNEEIKNLSHVAPEIVNNEANLNNISIKNVEKVLTELLLQCEYCNRTYADKKYLLLHQKKHTTEINYECITCKETFDSYTLATKHWLTKCSDEANLFYLPKMTYCEYCDRTFKSHEILYTHKIKKKHYTPKTFVCSDEPVVPDEKDTNEKGNESKDSIVKLIEYVLSEIKIPDNQLKEKTDFNGDNSEEKGIEKVADENAVAISDIKMEVMSETSSKSDLNSQELAETEKKKRGRKRKWPKQTTKAKRLAATVERGFKYQCERCNKIWDSVVDLEHHRETEHPANFKCEECDQVVHSAKALLIHSRAHQSLKPYVCEICKRCYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCDKCFLTGSVYYQHRLIHTNDRRYGCDICQKRFFRADALNNHRRIHTDERPYPCDICGRQFRQKGDRNKHVRTQHPS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -