Basic Information

Insect: Pyrrhosoma nymphula
Gene Symbol: znf423
Assembly: GCA_963573305.1
Location: OY754327.1:182969042-182978533[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.2 1.7e+02 6.0 5.9 1 23 3 25 3 25 0.98

2 18 3.5e-06 0.003 20.9 3.1 1 23 31 53 31 53 0.99

3 18 9.3e-06 0.0079 19.6 0.2 1 23 59 81 59 81 0.99

4 18 0.0083 7.1 10.3 2.2 1 23 133 155 133 156 0.94

5 18 0.093 79 7.0 0.4 1 23 294 317 294 317 0.91

6 18 0.041 35 8.1 0.2 3 23 513 533 512 533 0.99

7 18 0.11 89 6.8 0.0 2 20 608 626 607 630 0.89

8 18 0.00023 0.2 15.2 0.2 3 23 644 665 642 665 0.94

9 18 0.036 30 8.3 0.3 1 23 670 693 670 693 0.93

10 18 4.5 3.8e+03 1.7 0.0 1 23 700 725 700 725 0.84

11 18 0.43 3.6e+02 4.9 2.3 1 23 762 784 762 784 0.96

12 18 0.06 51 7.6 0.2 1 23 788 811 788 811 0.94

13 18 0.00043 0.36 14.4 1.9 2 23 893 915 892 915 0.95

14 18 0.013 11 9.7 0.4 1 23 943 966 943 966 0.92

15 18 7 5.9e+03 1.1 0.1 2 23 1031 1052 1030 1052 0.94

16 18 0.12 1e+02 6.6 0.1 1 23 1149 1172 1149 1172 0.95

17 18 0.0091 7.7 10.2 0.0 1 20 1265 1284 1265 1287 0.95

18 18 0.0041 3.5 11.3 2.3 1 23 1294 1316 1294 1316 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.2	1.7e+02	6.0	5.9	1	23	3	25	3	25	0.98
2	18	3.5e-06	0.003	20.9	3.1	1	23	31	53	31	53	0.99
3	18	9.3e-06	0.0079	19.6	0.2	1	23	59	81	59	81	0.99
4	18	0.0083	7.1	10.3	2.2	1	23	133	155	133	156	0.94
5	18	0.093	79	7.0	0.4	1	23	294	317	294	317	0.91
6	18	0.041	35	8.1	0.2	3	23	513	533	512	533	0.99
7	18	0.11	89	6.8	0.0	2	20	608	626	607	630	0.89
8	18	0.00023	0.2	15.2	0.2	3	23	644	665	642	665	0.94
9	18	0.036	30	8.3	0.3	1	23	670	693	670	693	0.93
10	18	4.5	3.8e+03	1.7	0.0	1	23	700	725	700	725	0.84
11	18	0.43	3.6e+02	4.9	2.3	1	23	762	784	762	784	0.96
12	18	0.06	51	7.6	0.2	1	23	788	811	788	811	0.94
13	18	0.00043	0.36	14.4	1.9	2	23	893	915	892	915	0.95
14	18	0.013	11	9.7	0.4	1	23	943	966	943	966	0.92
15	18	7	5.9e+03	1.1	0.1	2	23	1031	1052	1030	1052	0.94
16	18	0.12	1e+02	6.6	0.1	1	23	1149	1172	1149	1172	0.95
17	18	0.0091	7.7	10.2	0.0	1	20	1265	1284	1265	1287	0.95
18	18	0.0041	3.5	11.3	2.3	1	23	1294	1316	1294	1316	0.97

Sequence Information

Coding Sequence: ATGCCATTCCGATGCGAGTTCTGCAGCCGGCTCTTCAAACACAAGCGCAGCCGAGACCGACACATCAAGCTGCACACGGGAGACCGGAAGTATAGGTGCACGCAGTGCGAGTCGGCATTCTCACGCAGCGACCACCTTAAGATTCACATGAAGACGCACGACAACCAAAAGCCGTTCCAGTGCACGGTGTGCAACCGCGGCTACAACACGGCCGCCGCGCTCACATCTCACATGCAGTCGCACAAGAGGGGCGGTGGGAGAAACGGCGGGGGCGGGAGCACGCCCAGCCCGGGCCCCACGGCCCTGCCCACCTCCCCGGCCCCCAAAGCAGCCTCCACGCCCACCTTGGAGGCGGCCACTGGGCGGAGCAGCTCCGGAAGTCGAGGACCCAGTCCCCACCGCTGCCTTCACTGCACCGCGGGCTTCCGAAAGGCGGAGGAACTGCAGGCCCACGTGGCGCTGCATCACTCATCTGGCGTCCAGGCGCCGTCTCCGGTGCACGCGGAGACGCCGAGGCCCCGGGGCCGGCCCCCGTCCTCGTCCTTTCTGCCCCCGCGCAGCTGCTCCGCCTCCATCCCGTCACCCGTGGCCGTGGCGCCCAAACTGGCGTGCATCTACTGCACCAAGGACAGCTTCACCACCATGGAGGGACTGCAGCTCCACGTACAGGCGATGCACGGATCGATCCTCAACGGTGACCTGAGAGAGTTGGCGGCGGCTGTGGGAGTGGTTGGGGCTCTGCCGCACCTCGGCCCCACGCCGATCCCGCCCCCATCCAACCTCAGCCCCCGCCTGCCCTCGCCCACCACTTCGTCCTCCTCCACCATGCCCCCATCCTCCacatcctcctcctcgtcctcctccctccacctcatGCCTTTCTCCTGCGAGTTCTGCACCATGCGATTCGACGCGCCCACGGCTCTGCACAAGCACGCCCTGGCCGTCCACGCCATGCCCGCCGTGCTCGGCTCCCCTGCGGCCGCGCTCTCCGGCCCGCCCATGCACCCGCTCCACTCCGCCCACCACCTGCGGCACCCCTTCCCCTTCGTCGCCTCCTCGGCTCCGCCACCGTCGCTGCCCCCACCGCCCCCGCCCGCACCCCtgcctcctccaccctccctccccccggaGCAGATCAGGCCCACGGACCTGAGCAAAAAATCCACCGAGTCCAGATCCGAGGGTCCCGAGCCTCCCCGCGCGCACGAGAAATCTCAGGACTACCTGTCCCGATCGAAGCAGGATTACCACAGCATCAAAAACCACGTGGAGAGCAAGATGAAAGTCCAGGACTACAGCCTCCCCAATTACCCCAGCCACCGGCTGCTCCAACAGCAAGCCCACCATTTCCTCCACGCTGCGGCCAAGTCCCCGCCGGACTTTCTCTCCTTCGCCAAGAGCCTGAGGGACCTACAGGCGTCCGTTGCCAAGGCAGACTTCGGTTCACCGAGGAAGGTGCCCTCGGCAGCGGAGCCCAAGAGGCAGAGGACGCCCACGGAGGGCGAGCCCTCTTCGCTGGCCGGAACGCTGCTGTGCAACCAGTGTGACGCGGCCCTGCCGGACTTCGAGTCCTTCCGCTCGCACCTAAAGACACACCTGGAGGACGAAGAGGCGGCGGCGAGGGCTGCAGCATCTGGGGGCGCACCCGCGTCAGCCCCCGGAGCGCCCGGGGGCTTCACCCGACGCCGCTCGCGCAAGAGCAACCCGCACCCGAGGAGCGGTGGCGTCATTGGCGGAAGCGGTTCCCCTGGGATGACGGCGGGTTCGGCAACGGGGCCTTCGCCCCCCGCCGCCTCGCCACCGCCCAACCGTCGGACGAGGTGCCCCGAGTGCGAGGCGGAGTTCTCAACTGAGGCGGAGGCGGAGAGGCATGCGGTGGCAGCCCACTTTCAGCTCTCTCCCAACGGTGGGGCGTCCGAGTTCGGCTGCCAGTCGTGCGGCCGGAGGTTCCCTAAACCGGACGAATTGCAGAAGCACCTGATGGACCTGCACGCCCACCATCTCTACAGATGTGCCCTGTGCAAGGAGATGTTCGACTCGAAGGTCTCCATTCAGGTTCACTTCGCAGTGAAGCATAGCAACGAGTGCAAGCTGTATCGTTGTGCCGTTTGCGCCGACTTGGCGCCGTTCCGTTCGGAGCCAGAGTTCGTCTCCCACGTGCGCACCGTGCACCTCCTTCCGGCGTGGTCCGGACAAAGGCGACACCATTCCCTCCAGCGGCAGCCTTCCATTGCACCCGAAGCACAACAAGCTTGCCCACCGACAAACGGAGTCGCCCAGTTCCGGTGTCTGTTCTGCCACCTCAGTTTTCCAAGCGAACTTGAGCTCCAGTTCCACCTGACCACTCACCGTAAGGAGTTCAAGTGTGTCCTCTGCGACGAGGCCTTCCACGTGGAGTTCCTCCTGGATAGGCACGTCATGGAAGCCCACCGAGGTCACATGACTAACGGGATGACCACCTCAGCTGCACCCCCACCTCAGAGGCAAGAGAAGTCTTCAACCAGGACCACCCCCAAGAAGGCCTCTGCTCCCTCGACGCCCACCTCCCCTCAGCCAGCACCCTCCGCTCTGCCCAACGGGAGACCGGCCTCCAAGGAAGAGGAGGCTGCGTCGCGTGGCAACCAGACCATCGGCAACCCCCACCCCGCTCACCAAGTGGCGGTAGTGAGCCTCCAGTGTGCTTACTGCAACGAGCGCTGCAAGTCCCGCTCCGAACTGGAGACCCACACGAGGGCCATGCACTCTGCGGCCGTCAGCGCAAGCTCTAGCGGGGCCGTCGGTGGTGTTGGGGTCACAGGGACCGCCTCCGGCACAGGCGGAAAACACAAGTGCGTCATCTGCGACGAGGTGTGCGCCACCGCCGTGTCCTTGGCGGAGCACAAGCTGGCTCGTCACTGCAAGGTCCCGGAGGGCAGCGGTTGCTGTGTCTGCAAGGCTCCAATCGGCGGCGAGGACGAGTTCCACGCTCACGTTCGGAGACACGCCACACCTGGGGGCAACCGCGGGGGCAACGGGGCGGCGGCTAACCCCtcgtcttcctcctcatcctcgtcTGCGTCTTCCTCCCCGCCACCCCCTCTGCCCACGCCGTGCGTCGTGTGCAGGCAGACCCTTGTGTCCGAGGTGGAGGTGAGGATGCATGCAAGGTTCCACCTGAGACGGAGGGGTTCGGAGCAGCAGGCCCAGCAGTCGCAGTCCGCCCCTCAAGAATCCCAAGCCGCACCAACTACCCAGCAGGTGGACTCACAGCAAGCGGTGGGGCGGGAGAGGAGGAGCTGCTGCGTCTGCCTTCGCCCGCTCTCCGACGAGGAGGTTGTCGACAGCGGTGTGGAGGAGGGCTTCCCGGCGGTCTGCACCGAGTGCCGGGTCCTCTGCGGAGCTGCGGCCGGGGGCGGGGCGTCCGCTGGGAGGGGAATCCCGGGTGAGGACGACTCTGGTCCCTACCAGTGCATCAAGTGCCAGCGTGGTTTCCCCACCGAGAGAGAGATACGTGCCCACGTCCTGTCCGCGCATCTCCTCGACGTCGGCAGTCATTCTGTAAGTTGCGGTGCCGCGGTCCCGGGAGGGGCTGGGACCGGCAAAGGCGGAAGTACTGGCCTCGTTGCTCCTCCCGCCTCTTCCGACTTGGCCTGTCACCTGTGCTCCCCACCCTCCGAGTGGGACTCGCCCCTGAGACTGCAGGCCCACTTGATTGAGCACTCCTTCGGTGCCGCCTCCGTTGTCGGCGGCGGCAGGGACGCTTCTTCCGGTGGAGGGGCTGCTAGTGCCGTAGTATCCGGGGGCTCCAACTTCTCCTGCTATCTCTGCGGCTCCGTCTTTACCGCGGCGGCTGGGCTGCAGAGGCACATGCCCGGGCACGGACTGGCGCAGAGGCCGTACGACTGCTCCCGATGCAGCCTCCGCTTCTTCTTCAGGTCCGAGCTGGAGAACCACATGTTCTCCCATCGGGACGAGGAGGACGAGAGACAGAAGCGCGAGTTGGAGGAAGTGGCGGAAGAGCAGTCTGCGATGGACCTCGGGGCCAAGTCCCGAGCGGTGCCGAAAGTCGAAGTCAAGgaggaggtggagacggaggaaGGTGAAGCGGACGCATGTCTCGTGGAAGCGATGGATGTCGAGATGTCACTGAAACGTGAAGGAGACGAAGTTGAGCAGGATGGGTCCGAAGCCGCGACCGCGTTCGACCGCGACAGCGAAGCGGCTGCTTCGGCAAGGGACACTGAGGACGCCCCTCTGGATGGCGTCGAGACCAGTGCGCCCCGGAAACGGTCGAGGGCGCTAGACGCGGCAGAAGAGACTTCTCCGGTGATCAAGAAACGCCCTGAGTCTCCGCTGGACGTTGAGTGTGAATCATTTGCCGAAAAATGCGCCAGTTACTCATAG
Protein Sequence: MPFRCEFCSRLFKHKRSRDRHIKLHTGDRKYRCTQCESAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQSHKRGGGRNGGGGSTPSPGPTALPTSPAPKAASTPTLEAATGRSSSGSRGPSPHRCLHCTAGFRKAEELQAHVALHHSSGVQAPSPVHAETPRPRGRPPSSSFLPPRSCSASIPSPVAVAPKLACIYCTKDSFTTMEGLQLHVQAMHGSILNGDLRELAAAVGVVGALPHLGPTPIPPPSNLSPRLPSPTTSSSSTMPPSSTSSSSSSSLHLMPFSCEFCTMRFDAPTALHKHALAVHAMPAVLGSPAAALSGPPMHPLHSAHHLRHPFPFVASSAPPPSLPPPPPPAPLPPPPSLPPEQIRPTDLSKKSTESRSEGPEPPRAHEKSQDYLSRSKQDYHSIKNHVESKMKVQDYSLPNYPSHRLLQQQAHHFLHAAAKSPPDFLSFAKSLRDLQASVAKADFGSPRKVPSAAEPKRQRTPTEGEPSSLAGTLLCNQCDAALPDFESFRSHLKTHLEDEEAAARAAASGGAPASAPGAPGGFTRRRSRKSNPHPRSGGVIGGSGSPGMTAGSATGPSPPAASPPPNRRTRCPECEAEFSTEAEAERHAVAAHFQLSPNGGASEFGCQSCGRRFPKPDELQKHLMDLHAHHLYRCALCKEMFDSKVSIQVHFAVKHSNECKLYRCAVCADLAPFRSEPEFVSHVRTVHLLPAWSGQRRHHSLQRQPSIAPEAQQACPPTNGVAQFRCLFCHLSFPSELELQFHLTTHRKEFKCVLCDEAFHVEFLLDRHVMEAHRGHMTNGMTTSAAPPPQRQEKSSTRTTPKKASAPSTPTSPQPAPSALPNGRPASKEEEAASRGNQTIGNPHPAHQVAVVSLQCAYCNERCKSRSELETHTRAMHSAAVSASSSGAVGGVGVTGTASGTGGKHKCVICDEVCATAVSLAEHKLARHCKVPEGSGCCVCKAPIGGEDEFHAHVRRHATPGGNRGGNGAAANPSSSSSSSSASSSPPPPLPTPCVVCRQTLVSEVEVRMHARFHLRRRGSEQQAQQSQSAPQESQAAPTTQQVDSQQAVGRERRSCCVCLRPLSDEEVVDSGVEEGFPAVCTECRVLCGAAAGGGASAGRGIPGEDDSGPYQCIKCQRGFPTEREIRAHVLSAHLLDVGSHSVSCGAAVPGGAGTGKGGSTGLVAPPASSDLACHLCSPPSEWDSPLRLQAHLIEHSFGAASVVGGGRDASSGGGAASAVVSGGSNFSCYLCGSVFTAAAGLQRHMPGHGLAQRPYDCSRCSLRFFFRSELENHMFSHRDEEDERQKRELEEVAEEQSAMDLGAKSRAVPKVEVKEEVETEEGEADACLVEAMDVEMSLKREGDEVEQDGSEAATAFDRDSEAAASARDTEDAPLDGVETSAPRKRSRALDAAEETSPVIKKRPESPLDVECESFAEKCASYS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01212863;
90% Identity: iTF_00307115;
80% Identity: -