Basic Information

Insect: Pyrrhosoma nymphula
Gene Symbol: -
Assembly: GCA_963573305.1
Location: OY754334.1:70771607-70783891[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0052 4.4 10.9 0.0 1 23 520 543 520 543 0.92

2 9 0.052 44 7.8 3.5 1 21 557 577 557 579 0.94

3 9 1.4e-05 0.012 19.0 3.5 1 23 654 677 654 677 0.94

4 9 0.0012 1 13.0 0.4 1 23 776 799 776 799 0.94

5 9 1.1e-05 0.0097 19.3 2.7 2 23 834 855 833 855 0.97

6 9 1.1e-06 0.00095 22.5 0.5 1 23 861 883 861 883 0.98

7 9 6.8e-05 0.058 16.9 3.6 1 19 889 907 889 912 0.91

8 9 6.9e-08 5.9e-05 26.3 0.7 1 23 918 940 918 940 0.99

9 9 3e-06 0.0025 21.1 2.2 1 23 946 968 946 968 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0052	4.4	10.9	0.0	1	23	520	543	520	543	0.92
2	9	0.052	44	7.8	3.5	1	21	557	577	557	579	0.94
3	9	1.4e-05	0.012	19.0	3.5	1	23	654	677	654	677	0.94
4	9	0.0012	1	13.0	0.4	1	23	776	799	776	799	0.94
5	9	1.1e-05	0.0097	19.3	2.7	2	23	834	855	833	855	0.97
6	9	1.1e-06	0.00095	22.5	0.5	1	23	861	883	861	883	0.98
7	9	6.8e-05	0.058	16.9	3.6	1	19	889	907	889	912	0.91
8	9	6.9e-08	5.9e-05	26.3	0.7	1	23	918	940	918	940	0.99
9	9	3e-06	0.0025	21.1	2.2	1	23	946	968	946	968	0.99

Sequence Information

Coding Sequence: ATGGAAAACCCTGAGAGATCAGGCGAGCTAATGACGAATGTGCAACTTGTATCTCATCTTGATGAGGACGTAAAAATAGTCCACGATGGGGTTAAAGGTGGTCGAGATGAAGTTAGTCTCATCTCTTCAGATGATGTTAGTACTCAATATATGACCATACATTCAGAACAAACAATTTCAAAAGAGCCACAAGAGCATTTGGGTGATTGTGATTCGCAGTCTGACACTTTGACAGCATCTTCTCTGTCAGGAAATGGAGGACAAGGAGAAGAAATGCTTGCTCACGTTGTGCAGATGTCTTCAGGACAACATGCACTTGTTGTTGATATTATGGAAGCTGTTCCCACAAATGGGGGCAAACATCAGCCACATACTTCTTCGCAGCTCAAGGAAGGTGCTTATTATACCACAGTTCCTACCAGTGGAACTTCAGTCGGAAATCGCGTGACGCTTCTGAGTCCAGTTTCCGCCGGGAATACcgatcaccatcatcatcatatcCAACACCATTCCGTGCATCACAGTACAGAGTCCTTGCCTGTCGTTTCGCGGGCGTACATTCCAGACACAGATGGCATGGTTGTGACTACCAGTGGTCATTACAGCGAAACAGGAACAGCTGGGGTAGTAGAAGAAGATTTATTAACACATGACTTAACGGAAGAAGACCGGAGGTTGGCAGCTGCATTGGTTGCAGTTCAGTTAGTGCAGCAGCAAAAACACCAGCTTcatcagcagcagcagcaacagcaaATCCAACAGCATTTGCCAGTTTGTGTCTCTGATTCCACAAATGTCATAATGAATACCGCTGAGATTCAGGGGTTGATTGGAGTGGGCAAGGGTCTGCATCCAGAAGACACTCATGTAGTTGTAACCACCGATAAACCAGTGTCGTCTGCAATGGTGGTTGACTACATTCAGGCTGTTGAAGATGGTAGTGTTGTTAGTGGCAATCATGATAAAGCCGATGAAATGGTTGTGGCGTCGCCGCGTATTCGAACGAGGGATGTGGATGGTCCTTACGGTCAACCTCATCAGGATGACAACTCGTATGCAAAACTCCATGTCATTCTACCTCATCCGAAAAAGGCCATGATGGGTCAGGGTGCCGCAGTCCGTAATAGGCTGAAAAGGTTCCGGACTGAGATCGAAGAATCTTCCGTAGTGCACATGTTAGATACTACTTCTCCCGTAGTCGATGGTGTTCAGTATGTCACTGTGTCAAATTTAGGTACCACATTGAAAAATGAACATGGGGAGGTAATGGAAATGATGGTGGGCGAGGAGGCTGACGAATTGGGCGAGGGAATCGTGGAAGAGGCGGACGAGGAGGAGATATTGGAAGAGCTGGAAGACGAGGACGAAATGGAAGAGGTTTGCACAAGGGAGGAACTCGAGGCCTTGGATTACGAGACTGGTACCTCTGAGGGCCTCTTGGGACCTTCGGATCGAAGCTTGCCCCACAAGAAGAGAATCCCACCGAAGCTCAAAGGGAACACCTTGGTCATAGAGAGCGATGGGAAGAAGAAACTCACTCAGGTCCATGTGAAGTGTTACAAGTGCGAGGTGTGCGGCGAGGGACTTGCCTCGCAGGGTGACTACGAGGCCCACAAGGATCAGATGCACCCCCAGGAACAATCCATCGATGGTGTCAAGAAGAACCCCTTCACGTGCTTACTCTGCGGCCAGGCGTTCCCCAGCCAGTTCAAGTTCTTCGAGCACCTCAAGTGCCATTACGAACCTCTGCTCGAAAATGATCAAACCCAGAGGAAGGTCAAGGAGGAGGACACCGAGGTCAAGCATGAGGAGGAAACCTTGAATCAAGTCGAGGGCGTGGAGATGACCCTGGTTGATGAGAGCCAACACGTCATAACTCGAGCTCCAGAGGAGATGGCCCAAAAAGAGATACACATCATCCACCACCAGGAACAACCTCCGGGAGTTGAGCTGCCGGCCTTCCTTTGCACTCACTGCAACAAGACATTCCGACGGCAAAAGGCTTACGAGACCCACATGAACCTCGTCCACGGCccggaagacgaagaagaagaggaagaacatCAGCAACAGCACACCATAACCCACGAGACTGTCCTGGAGGAGACGGTTGTGGTCACAACCAAGAAGGACCAGCAGCAGACTGAGTGGATACCGACGTTCTTTGCGGAGGATGACGAcgacgatgatgatgacgaaGACGACTGGGGAGACAGCGACGTCCTGGACCGTCCAGTCCGGCGCCGGCAGCAGAACTCCGGTAGTGGTGTCGGAGACGTTGCAAACGATGGTACCACCGACGGACAAGGCATGGGAATCCATCACCATGTGTGCGAGGTGTGTGGTGGTGCCTTCCAGAGCCGGGCGCAGCTGAACCACCACGTCCAGGAGGAACACCCAGAGTCGGCGCACTCCGGGAACCAGAGGAAGAAGGCTAGGAAGGGTGGCGGAAGTGGTTCGGGTGGTGGCGGTGGGAGCGCCCGGAAGATAGAGCACATGACATGCACCACGTGCGGTCGAGTCTTCAACCACCGCAACTCCCTGGTATACCACATGCGCAGTCACACTGGGGAACGGCCCCATCAGTGCGAGGTGTGTGGGAAGAGCTTCTTCGCCGCAAGCGCCCTGAAGGTGCACATGCGTCTGCACTCTGGCGACAAGCCGTACAAGTGCGAGTACTGTGGCCGTCACTTTCGTCAGTGGGGAGACCTTAAGTATCACTGCATCTCCATACACTCTGATGAGAAACAGTACCAGTGCGAGTACTGCGGGAAGGACTTTGCTCGCAAGTACAGCCTGATAGTCCATCGAAGGATCCACACTGGGGAGAAgaattacaagtgtgatttttgTGAGAAGAGCTTCCGTGCCTCAAGCTATCTTCAAAACCATCGCCGCATCCACACtgAGATGGCCACCCGTGAGGGAGTGAAAAAAACTGCGAAATGGAGAGTAGATAAGAAGCGGTCGTTAATTTTGGTGCCCCATATTCTCGCGCTTGTGGGGACTGGGAAGGGGACAGAGAAGGACTATTGGTTCTACACCTTTGGTTCTTAG
Protein Sequence: MENPERSGELMTNVQLVSHLDEDVKIVHDGVKGGRDEVSLISSDDVSTQYMTIHSEQTISKEPQEHLGDCDSQSDTLTASSLSGNGGQGEEMLAHVVQMSSGQHALVVDIMEAVPTNGGKHQPHTSSQLKEGAYYTTVPTSGTSVGNRVTLLSPVSAGNTDHHHHHIQHHSVHHSTESLPVVSRAYIPDTDGMVVTTSGHYSETGTAGVVEEDLLTHDLTEEDRRLAAALVAVQLVQQQKHQLHQQQQQQQIQQHLPVCVSDSTNVIMNTAEIQGLIGVGKGLHPEDTHVVVTTDKPVSSAMVVDYIQAVEDGSVVSGNHDKADEMVVASPRIRTRDVDGPYGQPHQDDNSYAKLHVILPHPKKAMMGQGAAVRNRLKRFRTEIEESSVVHMLDTTSPVVDGVQYVTVSNLGTTLKNEHGEVMEMMVGEEADELGEGIVEEADEEEILEELEDEDEMEEVCTREELEALDYETGTSEGLLGPSDRSLPHKKRIPPKLKGNTLVIESDGKKKLTQVHVKCYKCEVCGEGLASQGDYEAHKDQMHPQEQSIDGVKKNPFTCLLCGQAFPSQFKFFEHLKCHYEPLLENDQTQRKVKEEDTEVKHEEETLNQVEGVEMTLVDESQHVITRAPEEMAQKEIHIIHHQEQPPGVELPAFLCTHCNKTFRRQKAYETHMNLVHGPEDEEEEEEHQQQHTITHETVLEETVVVTTKKDQQQTEWIPTFFAEDDDDDDDDEDDWGDSDVLDRPVRRRQQNSGSGVGDVANDGTTDGQGMGIHHHVCEVCGGAFQSRAQLNHHVQEEHPESAHSGNQRKKARKGGGSGSGGGGGSARKIEHMTCTTCGRVFNHRNSLVYHMRSHTGERPHQCEVCGKSFFAASALKVHMRLHSGDKPYKCEYCGRHFRQWGDLKYHCISIHSDEKQYQCEYCGKDFARKYSLIVHRRIHTGEKNYKCDFCEKSFRASSYLQNHRRIHTEMATREGVKKTAKWRVDKKRSLILVPHILALVGTGKGTEKDYWFYTFGS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00261382;
90% Identity: iTF_00261382;
80% Identity: -