Pumb028186.1
Basic Information
- Insect
- Pyrrhia umbra
- Gene Symbol
- THAP3_3
- Assembly
- GCA_963891755.1
- Location
- OY982946.1:4484540-4504219[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 3.6 3.2e+02 2.9 0.7 1 22 363 384 363 385 0.76 2 10 0.0023 0.2 13.0 1.2 1 23 392 415 392 415 0.93 3 10 0.33 29 6.2 0.2 1 23 419 441 419 441 0.92 4 10 0.047 4.1 8.9 1.0 1 23 446 469 446 469 0.98 5 10 0.0032 0.28 12.6 0.7 1 23 473 496 473 496 0.96 6 10 2.8 2.4e+02 3.3 0.1 2 15 509 522 509 529 0.77 7 10 0.0047 0.41 12.0 0.6 2 20 619 637 618 640 0.92 8 10 3.5e-05 0.0031 18.7 3.1 1 23 646 668 646 668 0.99 9 10 0.00027 0.024 15.9 2.8 1 23 675 697 675 697 0.98 10 10 0.0043 0.38 12.2 4.9 1 23 703 726 703 726 0.90
Sequence Information
- Coding Sequence
- ATGAGGTGCAGTGTACAGAACTGTTCTAATGATACTAAAAGAACTACTAAAAGCCATGGGATCACATTTCATATGTTCCCGAAGCAGCTAAGTCTCCGCTCTGCATGGGTGGAGGCTCTTGGCATGACGGACTGGGAGCCAAAAGACAGGAGCACGGTCTGCTCTGAACATTTCAGGAACGATGACTTCTATGAGACCAAGAGAGGGCTACGGAGAATAAAGTGTGGAGCAGTACCGGTTGTGATGCAAGACTCCGCTGATGATATGGATGCGCCGGCCGCTCTGAGGGTGTGCCGAATTTGTCTCGTAATGAACGCTAAAATGTACCACATAAGAGAGTTCAAACTGGACCAAATGTATGAGCAGATAACAGGATTGATGGCTGGTTCGGAAGAGAGACTGCCGCAGCGGGTTTGCTGGGAGTGTGGAGCGAGGCTGTCGGCAGCGTGTCGGTTCAGAAACAAAGCCCTTCGCAGCGATGCCTTGCTGCACGAACTACTACATCCGGACACATATATAAAAATTCGTGATATCAAATCAATTAATAGAGCACACCATGGCCTAACATcgaatttaatacataaaatttatgaaaatgccGACTATGATATCCATATAGATGTGAGtataaaaactgaagaaaacctCGATATAACTGAGGATACACAAACACCAGGACATACCGACATACCGAATGACAATATCGAAATTGAAGTCAAAAGTCTAGCACCGATAGTTGAAGTCGAAATCAAAGACGAAAGTAGTAAtggtatattttttgatgaGTATGATAACtttgatgacgatgacgataaGGTGCTTAGCGAAGTGTGCTCGGAGAAGAAAGGTAAAGATAAAGTTAAGAAAAGGAAGGAGAAGGTCTTGAAGAAGGTTAAGGAGAAGAAGACTGATGGAGAAGATGATCCGGATACTACTAGTGATagGTACAAGAAAACAGATGTAAAACGTCGCAGAACCAACGAAGCCTTAGACGAGGCGTTATTCACGATAAGCCCGTTGACTTACGATCAGCAGATTGAGGAGATATTAAAACGGCAGGAGAGCACTAATTACACCAGCGCGCCCTTCAAGTGCACGGTCTGCTACCGAGGGTTCCTCATCAAGGATAGGTATACCGCTCACGCTGTGCGGCATAGTGAGCAAAGTGGTGCATACGAGTGTTTTATATGTAAAACCAGGCTAAAAACGAGTCGCGCTTTACGAAAGCATTTGACGGCACAACATACCGAACAATACAGCTGTAAAGGATGTCCGTTTGTCACGagaaatagAGGTGTTGCGAGGGAGCATGAGAAATGGCACGCGGGCACCAAGTACCAGTGTCCACACTGTGCCAGTGAGTTCGATAAATTGACAACGTACATGGGCCATATAAGAATTAAGCATGTATCGGATTTCGTATGTGAATTATGTGGGTACACTTTTGTCAGCAAAAAGGGCATCGATGTACACAAGAAAAAGAAACATCGGCTAGCTGATAAAACTTTGACTCTGGAAGGGCCTTACTGTGATATATGCGACGTCAAGTTTGTGTCTGAAGAGGCACACGGCAGACATCTCAAACTGTCTTCCAGACACAGCAGCGATCATGATCCgAATAGGATCCGCAACGATTCTCAAAGTATGAACGCGGAACGCAACGGTCGAGTCATGCGGAGGATAGAGAGGCGGCCCGTCATCCATCCCCGGGGGCCCGCAGAGGGGGACCCCAACGAGCCTCACGCACCCCTTAGCTGTGAACAGCTACGTGACCTAAGGGTGTATGCACAGCACTTCAGACGAGCTCACCCGGACAAGAACCGAACCAAGTACCCCGCGATGAAGACCCCCTGCATGTGCGAACAGTGCGGGAAAATATTTCAGAGCATGGCGTTGCTAAAAGACCATATGTGGGTCCACACAGGGGAGAAGCGGTTCAAATGTGACCGCTGCACCAAAAGCTTTACTCAGAAGACGAACCTGGTGTTTCACATGCGAGTGCACAGCGCGACGCGGCCGAGCTACGAGTGTCCGTTGTGTGGAAAACATTTTGCCTTCTTCAATAATAGGAGGAGACACATGTTTATTCACACCGGTTTGAAACCGTTCAAATGTGATACATGTGGCAAGTGTTTCACGACGTCTGGCGAACACCGAGCACACGTGGAACATGTGCATTTAAAAAAGCCCTGGCCTAAGCGGGCTCGGCAGAGAGCGAGGGACTGGAAGTGTGATGACCCCAGCATTGAAGATTAG
- Protein Sequence
- MRCSVQNCSNDTKRTTKSHGITFHMFPKQLSLRSAWVEALGMTDWEPKDRSTVCSEHFRNDDFYETKRGLRRIKCGAVPVVMQDSADDMDAPAALRVCRICLVMNAKMYHIREFKLDQMYEQITGLMAGSEERLPQRVCWECGARLSAACRFRNKALRSDALLHELLHPDTYIKIRDIKSINRAHHGLTSNLIHKIYENADYDIHIDVSIKTEENLDITEDTQTPGHTDIPNDNIEIEVKSLAPIVEVEIKDESSNGIFFDEYDNFDDDDDKVLSEVCSEKKGKDKVKKRKEKVLKKVKEKKTDGEDDPDTTSDRYKKTDVKRRRTNEALDEALFTISPLTYDQQIEEILKRQESTNYTSAPFKCTVCYRGFLIKDRYTAHAVRHSEQSGAYECFICKTRLKTSRALRKHLTAQHTEQYSCKGCPFVTRNRGVAREHEKWHAGTKYQCPHCASEFDKLTTYMGHIRIKHVSDFVCELCGYTFVSKKGIDVHKKKKHRLADKTLTLEGPYCDICDVKFVSEEAHGRHLKLSSRHSSDHDPNRIRNDSQSMNAERNGRVMRRIERRPVIHPRGPAEGDPNEPHAPLSCEQLRDLRVYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGKIFQSMALLKDHMWVHTGEKRFKCDRCTKSFTQKTNLVFHMRVHSATRPSYECPLCGKHFAFFNNRRRHMFIHTGLKPFKCDTCGKCFTTSGEHRAHVEHVHLKKPWPKRARQRARDWKCDDPSIED
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01441464;
- 90% Identity
- iTF_01285611;
- 80% Identity
- iTF_01285611;