Basic Information

Insect: Pyrrhia umbra
Gene Symbol: zfh1
Assembly: GCA_963891755.1
Location: OY982924.1:290053-293215[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.02 1.8 10.0 0.3 1 23 44 66 44 66 0.94

2 8 6.1e-06 0.00053 21.1 2.8 1 23 77 99 77 99 0.98

3 8 1.9e-06 0.00016 22.7 6.2 1 23 108 130 108 130 0.99

4 8 0.00013 0.011 16.9 1.0 1 21 136 156 136 157 0.95

5 8 0.00034 0.03 15.6 2.2 1 21 413 433 413 434 0.93

6 8 9.9e-06 0.00086 20.5 1.1 1 23 735 757 735 757 0.94

7 8 8.2e-05 0.0072 17.6 7.6 1 23 763 785 763 785 0.98

8 8 0.053 4.6 8.7 8.1 1 21 791 811 791 812 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.02	1.8	10.0	0.3	1	23	44	66	44	66	0.94
2	8	6.1e-06	0.00053	21.1	2.8	1	23	77	99	77	99	0.98
3	8	1.9e-06	0.00016	22.7	6.2	1	23	108	130	108	130	0.99
4	8	0.00013	0.011	16.9	1.0	1	21	136	156	136	157	0.95
5	8	0.00034	0.03	15.6	2.2	1	21	413	433	413	434	0.93
6	8	9.9e-06	0.00086	20.5	1.1	1	23	735	757	735	757	0.94
7	8	8.2e-05	0.0072	17.6	7.6	1	23	763	785	763	785	0.98
8	8	0.053	4.6	8.7	8.1	1	21	791	811	791	812	0.96

Sequence Information

Coding Sequence: ATGCCTGATAATTTTCAACGTCCCATTATGAAGAAATCTGTCCGTCCCCTGGCTGGCGGTGGGTCTGATGGCAAGCCATCTGAGGAAGAGGAGGAGCGCGGTGGCTCCCCACTCGGTCCCGGCGGGCCATTCTCCTGTAGCCAGTGCCGCGGAGCCTATCCTACGCGCGAGCAACTCGAGCGACACGAGACCCTGCACGCGCCCAACACACAGGTGGATACAGTCAAATATTCATGCAAGATCTGCCACAAAAGCTTCGCAAACGTATACAGATTGCAGCGGCACATGATCAGCCATGACGAGAGCGCATTACTTCGCAAGTTTAAATGCAATGATTGCGATAAAGCTTTTAAATTCAAGCATCACTTGAAAGAACACTTGCGTATACACAGCGGAGAAAAACCTTTTGAATGTGCTAACTGTGGCAAAAAGTTTTCCCATTCAGGCTCATACTCTAGTCACATGACCTCCAAAAAGTGTCTCGTCATGAATCTCAAGATGGGTCGGATAAAACCCAATAATCCTGCACTCAACCCCGAAAGAAGTCCATCACGAAAACGGACTAACGCCATGGTTGCCTctcagttaaataataatatatcgccAAACGGAAATTCTTTTCTTCCCATGCCTGCTGCTTTCTTTGCATCGATGTCGTCACAAGAAAATAGCTTCCATCGACCACCCTTAGGCCAACCTGGAATTCCCTTCTACATGCCTCCTGGCATGCCAATGAGTCCCGCGGGCGGGATAGCTCCTTACAGTATACCAGCCACGCTCAGCCAATTTTTAGAGCAGCTAGCTTCATCGCAATATCAACCAAGAAAATTAGAAAATCTTGCCAGTCCGAAGCCTACAACTCCTCCACCAGCAGATCCTGAAGACCTCATCGAAGAAGTTACGGAAGATGATGATAAACGATCAGAAGGAAGCGCTGAACTCGTAATGGACATTGAAGATGAGGAAGCTGTGTCGATAAAAAAGGAGCAGGAGGAACGAGGTAGCGATTTGCGGCCTCCATCTCGCGACTTCGATTCCGTCCCTTTAAATAACAACTGCCATAATGCTGAAAATCCAGGTTTCAATTCCATATTACAGTCTGTAAGCGCATCTGTGACGAAACATTTCTTTCGAGCAAACATGGAAAAGCTCTCGCCTATCTCGGGCAATGTTTGCCCAAATATAGattcaccgcccactcctcacATCACAGTAAAGGAGGAACCGGAAGATACACATAGATGTTCCAAATGTCACCTAACTTTCACTAGCAAGAGTGACTTATTAGATCATGAGAAAGTACTTTGCGGAAATATGTTTAGGAAACATGAAGGTTTGGCAGCTCAAGTAGCCGAAACGGTAGCTCTTAATAGATTAGAAGCCGAAATACATGCCTCCATACATAATGGAATTAGTGCAAGTGAAGACGAAGACTTTAATAGAGATGACAGAGATGATAAAGTATCGATTCACGACAATGATAGAAAAATAAGGGTTCGTACAGCATTAAGTGAAGAACAACAAATAGTTCTAAAGGAGCATTACGCGTTGAATCCACGGCCGAACCGTGAGGAGTTTAAAAGAATAGCTCAGCAGATCGGTCTCGACAACAGAGTGGTGCAGGTGTGGTTTCAAAACAACAGAGCTAGAGAACGACGTATGACGCAAACTATGACCACCTCTGACCAGCCATTAGATTTATCTACAAAGAAATCCAATCCGTCGGTTACGTCGAGCCCGTCACCATCGCCGCCGTGCAGCATTTCTGTGACACATTCCGACTCTGAAGAAGCAGTAAATCTAAGCCAGAAATCCTCTCGAAGTACAACTCCTCATCGTACCAATTATCTGAATACTTATCCACATTCCAATTGCTCTTCATCTTCCTTCACCGATTTCCGATTGTCTCCATCACCTGGAGAAAGTATTAATGGGCACAAACGATTGCTACCACAAAAATTACATGTCAACCCCTTAGTACCTATGGATAAACTACTTCAATACAATGACATTGCTAACGCGCGATCTCCTATCCTTAATATGCACCTGACATCTGATATGAATCGACAAGGTTCGAGTCCATCATACGAACGTCCACCTTGGGATGAAATGCAAGCACCAAACGAGATCGAAGACGAAGCGACAGTACTTAAGAAGAGCAAACTCAAGCAAGGGTCTGATATTAAAGAAAGCGAAGGCCAATTCGTATGTGATCAATGTGATAAGACCTTCGTCAAGCAAAGCTCCCTCGCGAGACACAAGTATGAACATTCAGGCCAACGCCCGTACAAGTGTCTGGAATGCCCGAAAGCATTCAAACACAAACACCACCTGACCGAACACAAGCGCCTGCACACCGGTGAGAAGCCCTTTCAGTGCTGCAAGTGCTTCAAGAAGTTCTCTCATTCGGGCTCCTATAGTCAGCATATGAACCACAGGTTCGCTATATGCAAGCCCTACAGGGACTAA
Protein Sequence: MPDNFQRPIMKKSVRPLAGGGSDGKPSEEEEERGGSPLGPGGPFSCSQCRGAYPTREQLERHETLHAPNTQVDTVKYSCKICHKSFANVYRLQRHMISHDESALLRKFKCNDCDKAFKFKHHLKEHLRIHSGEKPFECANCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIKPNNPALNPERSPSRKRTNAMVASQLNNNISPNGNSFLPMPAAFFASMSSQENSFHRPPLGQPGIPFYMPPGMPMSPAGGIAPYSIPATLSQFLEQLASSQYQPRKLENLASPKPTTPPPADPEDLIEEVTEDDDKRSEGSAELVMDIEDEEAVSIKKEQEERGSDLRPPSRDFDSVPLNNNCHNAENPGFNSILQSVSASVTKHFFRANMEKLSPISGNVCPNIDSPPTPHITVKEEPEDTHRCSKCHLTFTSKSDLLDHEKVLCGNMFRKHEGLAAQVAETVALNRLEAEIHASIHNGISASEDEDFNRDDRDDKVSIHDNDRKIRVRTALSEEQQIVLKEHYALNPRPNREEFKRIAQQIGLDNRVVQVWFQNNRARERRMTQTMTTSDQPLDLSTKKSNPSVTSSPSPSPPCSISVTHSDSEEAVNLSQKSSRSTTPHRTNYLNTYPHSNCSSSSFTDFRLSPSPGESINGHKRLLPQKLHVNPLVPMDKLLQYNDIANARSPILNMHLTSDMNRQGSSPSYERPPWDEMQAPNEIEDEATVLKKSKLKQGSDIKESEGQFVCDQCDKTFVKQSSLARHKYEHSGQRPYKCLECPKAFKHKHHLTEHKRLHTGEKPFQCCKCFKKFSHSGSYSQHMNHRFAICKPYRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00281695;
90% Identity: iTF_00171643;
80% Identity: iTF_01285433;