Basic Information

Insect: Pyrrhia umbra
Gene Symbol: Znf296
Assembly: GCA_963891755.1
Location: OY982916.1:7745180-7751789[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.13 11 7.5 0.2 1 21 17 37 17 38 0.92

2 12 0.0007 0.061 14.6 0.7 3 20 52 69 51 73 0.96

3 12 0.12 11 7.6 2.0 2 23 113 134 112 134 0.96

4 12 0.0081 0.71 11.3 0.3 1 20 238 257 238 259 0.92

5 12 4.4e-05 0.0039 18.4 0.8 1 23 267 290 267 290 0.98

6 12 2.1e-05 0.0018 19.4 2.2 1 23 311 333 311 333 0.98

7 12 4.4e-06 0.00038 21.6 4.2 1 23 340 362 340 362 0.98

8 12 1e-07 8.9e-06 26.7 2.3 3 23 376 396 374 396 0.96

9 12 2.4e-05 0.0021 19.3 3.2 1 23 402 424 402 424 0.99

10 12 1.3e-06 0.00011 23.3 2.5 2 23 431 452 430 452 0.96

11 12 1.2e-07 1.1e-05 26.5 1.4 1 23 458 480 458 480 0.99

12 12 0.0029 0.25 12.7 0.1 1 23 486 508 486 508 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.13	11	7.5	0.2	1	21	17	37	17	38	0.92
2	12	0.0007	0.061	14.6	0.7	3	20	52	69	51	73	0.96
3	12	0.12	11	7.6	2.0	2	23	113	134	112	134	0.96
4	12	0.0081	0.71	11.3	0.3	1	20	238	257	238	259	0.92
5	12	4.4e-05	0.0039	18.4	0.8	1	23	267	290	267	290	0.98
6	12	2.1e-05	0.0018	19.4	2.2	1	23	311	333	311	333	0.98
7	12	4.4e-06	0.00038	21.6	4.2	1	23	340	362	340	362	0.98
8	12	1e-07	8.9e-06	26.7	2.3	3	23	376	396	374	396	0.96
9	12	2.4e-05	0.0021	19.3	3.2	1	23	402	424	402	424	0.99
10	12	1.3e-06	0.00011	23.3	2.5	2	23	431	452	430	452	0.96
11	12	1.2e-07	1.1e-05	26.5	1.4	1	23	458	480	458	480	0.99
12	12	0.0029	0.25	12.7	0.1	1	23	486	508	486	508	0.97

Sequence Information

Coding Sequence: ATGGaagcCGTCAAATCTGAACATGAGAGTCTAGAACGTAAGTCATGCTTTTTATGCAAAAGCTGCTTAGTCGTTTTCGATACACGCGATAAATTATTAGATCACCAGAAGATATGCATAAAAGttgAATGTGATGAAACCAACCGTAGCTTCTGCCCACTTTGCGGAACATGTTACAATGGCGCTGAAAATTTAACAAAGCATATGTGGGAAAGTCATGCAGATCTTATGGGACCAAAAAAGAGAGGCAGGCCTAAAAAAATGTTGACAAGTACCATTCTTAACAAGTTATCAGAAAATGGGTTTTGTATAACTTCAATGCCAGCTAAAAAGATTGAGTGTGCATTTTGCAAGCATCATTTCCAAACCAAAGAAGAATTAGGATCACACGCCATTACTCATAAAGaTACGAAGGTGATACGTTGTCTTGTTTGCAAGAGAATATATCTCGACACACAGAAGTTTCATCATCATAACTGTGTTGAAGATAAAGCTGATCTAAATAATGTCGAAAATGATTCGGCGAAAACAGAACCCAATAAAAAAAAGCAGCAGCATTTGTCGTCAGAAATCACACTGCGAGAATTTATAGACCCCAACATAGATATGGAGATTATCAACTTGCTTCAAGTATGTACTGCTTGTAGCTGCATATTGCAATCAGAAGCGGATCTAATTAACCATCGCGATGCTGAACATCCCGAACTGTCCCATCGGTGTAACCTCTGTACCAAGgtATTTGCTTCTTTGCGTTCAGCGGCACGCCATAGGAGCATCTGTAAGcaaattgaaagaaaatataaatgtagCACATGTGGATTGAAGTTCGCATATGAAATATCATTGAATAAGCATATTTTAAGATATCACGAGGGTCAAAGCGTGTCAGTCAAATTTATTGATTCAAAAACCAAACGAGAAGAGAGACAATTTCAGTGTGATACTTGTAATAGAAGTTTCTACAAGCGAGACTTACTTGTTAAGCATACTAAAATACACATGCCAATTGAAAACTTCTTCGAATGTGACATTTGTAAAAAGAAGTTTCATAGAAGTGATAACTTACGTTCTCACAAACGAGTTCATGATCTGCAGCGCGAGAAGGGTTCGACTAATAATTGCTTGTGCCTCTACTGTGGCCGCAGTTTCTCTAACTCGTCTAACTTAATAGTGCATATGCGGCGCCACACCGGAGAGAAGCCCTACAAATGTGATTTTTGTGGCAAAGGTTTTCCGAGGTCTTCAGATCTGCAGTGTCACAGACGGTCTCACACCGGAGAGAAACCTTGCGTCTGCCGTGTTTGTGGTAAAGGGTTTTCTCGCAGCAATAAGTTGTCCCGTCACATGCGAGTCCATACTGGCCAGCGGCCGTACAAGTGTACGTACTGTGAGAAGGCGTTCTCGCAGAGCAACGATCTCAACCTGCATATACGTCGACATACTGGCGACCGGCCCTACATCTGTGAAGTATGCGGCGACCGATTTATccagGGTACAGCATTGCAGAATCACAGAAGAGCCCATGGTCACTTTCCTGCTCCTCCCGCAGCAGAGACACCTTCTGAGGCACAAACACTCACTTATACAGTCCAGAATATAAATCATAGTAATTAG
Protein Sequence: MEAVKSEHESLERKSCFLCKSCLVVFDTRDKLLDHQKICIKVECDETNRSFCPLCGTCYNGAENLTKHMWESHADLMGPKKRGRPKKMLTSTILNKLSENGFCITSMPAKKIECAFCKHHFQTKEELGSHAITHKDTKVIRCLVCKRIYLDTQKFHHHNCVEDKADLNNVENDSAKTEPNKKKQQHLSSEITLREFIDPNIDMEIINLLQVCTACSCILQSEADLINHRDAEHPELSHRCNLCTKVFASLRSAARHRSICKQIERKYKCSTCGLKFAYEISLNKHILRYHEGQSVSVKFIDSKTKREERQFQCDTCNRSFYKRDLLVKHTKIHMPIENFFECDICKKKFHRSDNLRSHKRVHDLQREKGSTNNCLCLYCGRSFSNSSNLIVHMRRHTGEKPYKCDFCGKGFPRSSDLQCHRRSHTGEKPCVCRVCGKGFSRSNKLSRHMRVHTGQRPYKCTYCEKAFSQSNDLNLHIRRHTGDRPYICEVCGDRFIQGTALQNHRRAHGHFPAPPAAETPSEAQTLTYTVQNINHSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01526338;
90% Identity: -
80% Identity: -