Basic Information

Insect: Pyrochroa serraticornis
Gene Symbol: zfh1
Assembly: GCA_905333025.1
Location: HG995152.1:30468064-30477296[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0035 0.25 12.2 1.6 2 23 32 54 31 54 0.97

2 9 0.00028 0.019 15.7 0.5 3 23 87 107 85 107 0.95

3 9 8.7e-06 0.00061 20.4 0.6 2 23 114 135 113 135 0.97

4 9 5.6e-06 0.00039 21.0 5.9 1 23 144 166 144 166 0.99

5 9 1.3e-05 0.00093 19.8 0.9 1 21 172 192 172 193 0.95

6 9 0.032 2.2 9.2 1.0 1 20 431 450 431 452 0.95

7 9 6e-06 0.00041 20.9 2.0 1 23 792 814 792 814 0.94

8 9 0.00016 0.011 16.4 9.4 1 23 820 842 820 842 0.98

9 9 0.0076 0.53 11.2 4.0 1 21 848 868 848 869 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0035	0.25	12.2	1.6	2	23	32	54	31	54	0.97
2	9	0.00028	0.019	15.7	0.5	3	23	87	107	85	107	0.95
3	9	8.7e-06	0.00061	20.4	0.6	2	23	114	135	113	135	0.97
4	9	5.6e-06	0.00039	21.0	5.9	1	23	144	166	144	166	0.99
5	9	1.3e-05	0.00093	19.8	0.9	1	21	172	192	172	193	0.95
6	9	0.032	2.2	9.2	1.0	1	20	431	450	431	452	0.95
7	9	6e-06	0.00041	20.9	2.0	1	23	792	814	792	814	0.94
8	9	0.00016	0.011	16.4	9.4	1	23	820	842	820	842	0.98
9	9	0.0076	0.53	11.2	4.0	1	21	848	868	848	869	0.96

Sequence Information

Coding Sequence: ATGGCGGCCTCTCCCCTCGAAATTTCCCCCTTGACGAACGGTGTCGTCAGTAAGGACGGCGACGATCCGGCAACTGCCAGCGACTACTACATAAAATGTCCACAATGTCAAAAGGGCTGCCAAACGTTTCAGGCGTTGAAAGAGCACATGGAAACATCGCACGCGGAACTGACGGCGGCGTCGGAAGCCGCGTTGTCGACGTCGAACGCCGCGTCACCGACGCCGAGTATGGCGGGTACGCCAGGAGGACCGTACGGATGTTCCCAGTGCACCACCAGCTTCGCCAACAAAGACCAGCTGGAAAAGCACGAGCTCCTACATTCGCCCAACGCTCAAGTGTCCTGCAAAATTTGCAACAAAACGTTTGCCAACGTCTACCGCCTCCAACGACACATGATCAGTCACGACGAGAGCGCGGTGCTCAGAAAATTTAAATGCACAGAGTGCGAAAAGGCATTCAAGTTCAAACACCATCTTAAGGAGCACATCAGAATTCACAGCGGTGAGAAACCGTTCGAATGTCCCAACTGCGGCAAGAGATTTTCACACTCAGGGTCCTATTCTAGTCACATGACGTCCAAAAAATGCTTAGTGATGAACCTGAAATTAGGCCGTGCCCGCGCCCCTTCCAGCAGTTCCCTCTTGGAGAAATCTTCCCAACAGAACCGTAACCTCAAAAGATCCAACATAAGTCCAATCAACAACAACATCACAACGAGTCCAAACCACAACTCCTATCTGCCCATTCTGCCAAAATACTCAGAAGCAGCTGCGGCCTTCCTCCAATCTTCATTAGCGAGTAACTCTCCGATGTCGCCCTTCTACCTCGCCCCACCCGGTCTCTTAAATTCCGGCCATTCAATAACCCCCTATTCCATTCCTCATTTGGGCCACATCTTCGAGCAATTACAACAGAGCGCGTCGCCGTTACGGCCTCCAATATTAGACAGTTCCGACAACAACCCGGAAGATTACAAATCTCGAGAAACCAACGCAATTTCTCCCAAAACTGAAGACGTTCCTAAAAGCAACTCGTCGAGTTGTGGAGAATTGGTTATGGACGAGGACGTCGAGGAGAACCAAGACAATCACGAAAATGTCGTGGTGAAAAGTGAACATCCCACCCCAGAAGCCGGGACCAGCAACGACGACGATTTGGAAGCGGTAAAACGCATTTTGGAAACTGTAAACGCAACTGTTACCAAACAGTTCTTGCAGGCTAACATGCAGAAGTTTTCGTCCGAATCATCGAGCGATTGCCACAGCTTCGCCTCACATTCCCCCAAAGTTTACACTTGCTCCAATTGCAAGATCAATTACGAGACTTCGACGCAGTTGGAAGATCATGAGTGCGACATCAAAAGTGAAGGTTTAGCAGCGAAACTCGAAGATGCGCTAACGACGAAGTCTGAAGACGTCCAGAACGGCGGCAGCGTTAGCGGAAATGAAGATAAGAATGAAGATGAGTTAGATTGCGAATCTGTGACCACCACTGATCACGTTTCCGAAGATGGAAGAAAAGTTAGAGTGAGATCTTTGATTTCCGACGAACAATTGAAGGTGTTAAAAGACAATTACAAATTAAACCCACGACCCAAAAGAGAAGATTTGGAGAAAATTGCGGAAACTATAGGGTTTCCAGTTAGAGTGGTTCAAGTTTGGTTCCAAAACACACGCGCTAGAGACAGAAGGGAAGGACGTCTTATCCAAGTACCCTATAATCCAGCCCCGACGATACCATTGCGTTATCCGTTGATGCCTTCGACTACTACCCCTCAACTCAGCCACAAGATAATTCCGTCATTGAGCATCTCCCCCAGTTATTCAGAACAACCTCTCGACCTTTCAACAAAAAGAGGACAAACTTCAGCTGAATCATCGCCGACTAGCTCGCCGAGAAGACCAACGTCCGTCAATCATTACCAAGAGAGCAACGATGAAGTCGTCAATTTAAGCAGAAAATCTTCTAGAAGTCCAACTCCTTACATCTACCCCAACCACTATCAAAATTCAAATTCTTCGGAACCTCGCCAAAGTCCATCTCCTGTTGATTTCAACACCAACAGTCGCTTGGCGCAAATTCTGGCTCAACCCGCCCATAAGTTGCCGCTTCCCGGAATGGGTTTGGTACCTATGGAACAGTTGATGCAATTGGGCACAGATTTGCCCGGTTTATCCCAGTTTATCACCAGCAAACTCAGTAGTATGAGTCCAAATGCAAGAAAGAGGTTATGGAGCGAGAATGGTGACATCTTGAGCGATTCGTTTCAAGACGATGATCTTGCCGCCAAGAGAAGCAAGGTCTCGCAGTACGTATTGAAGAGTCTGGGGAGTCCGGTTTTGGGAAATCAAGAACCTGAAATCGAGGGACAGTTCAGTTGTGACCAATGTGATAAATCGTTTTCCAAGCAGAGCTCACTGGCGAGGCACAAATACGAACACTCAGGTCAGAGACCTCACAAATGTGACGAATGTCCGAAGGCCTTCAAGCACAAGCACCATCTTACGGAGCACAAGCGTTTACACAGCGGCGAAAAACCCTTCCAGTGCCTCAAATGCCTGAAGAGGTTTTCCCATTCGGGTTCCTACAGCCAGCACATGAATCACCGCTATTCCTACTGCAAACCCTACAGAGAGTAA
Protein Sequence: MAASPLEISPLTNGVVSKDGDDPATASDYYIKCPQCQKGCQTFQALKEHMETSHAELTAASEAALSTSNAASPTPSMAGTPGGPYGCSQCTTSFANKDQLEKHELLHSPNAQVSCKICNKTFANVYRLQRHMISHDESAVLRKFKCTECEKAFKFKHHLKEHIRIHSGEKPFECPNCGKRFSHSGSYSSHMTSKKCLVMNLKLGRARAPSSSSLLEKSSQQNRNLKRSNISPINNNITTSPNHNSYLPILPKYSEAAAAFLQSSLASNSPMSPFYLAPPGLLNSGHSITPYSIPHLGHIFEQLQQSASPLRPPILDSSDNNPEDYKSRETNAISPKTEDVPKSNSSSCGELVMDEDVEENQDNHENVVVKSEHPTPEAGTSNDDDLEAVKRILETVNATVTKQFLQANMQKFSSESSSDCHSFASHSPKVYTCSNCKINYETSTQLEDHECDIKSEGLAAKLEDALTTKSEDVQNGGSVSGNEDKNEDELDCESVTTTDHVSEDGRKVRVRSLISDEQLKVLKDNYKLNPRPKREDLEKIAETIGFPVRVVQVWFQNTRARDRREGRLIQVPYNPAPTIPLRYPLMPSTTTPQLSHKIIPSLSISPSYSEQPLDLSTKRGQTSAESSPTSSPRRPTSVNHYQESNDEVVNLSRKSSRSPTPYIYPNHYQNSNSSEPRQSPSPVDFNTNSRLAQILAQPAHKLPLPGMGLVPMEQLMQLGTDLPGLSQFITSKLSSMSPNARKRLWSENGDILSDSFQDDDLAAKRSKVSQYVLKSLGSPVLGNQEPEIEGQFSCDQCDKSFSKQSSLARHKYEHSGQRPHKCDECPKAFKHKHHLTEHKRLHSGEKPFQCLKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01329687;
90% Identity: iTF_01329687;
80% Identity: iTF_01283271;