Basic Information

Insect: Pyrochroa serraticornis
Gene Symbol: topi
Assembly: GCA_905333025.1
Location: HG995159.1:8567111-8568260[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0038 0.26 12.1 0.2 1 23 98 121 98 121 0.95

2 9 7.6e-08 5.3e-06 26.9 4.3 1 23 127 149 127 149 0.97

3 9 1e-05 0.00071 20.2 0.3 3 23 157 177 155 177 0.96

4 9 8.6e-05 0.006 17.3 2.7 1 23 183 206 183 206 0.96

5 9 1.3e-06 8.8e-05 23.1 0.8 1 23 214 236 214 236 0.98

6 9 0.00034 0.023 15.4 6.5 1 23 242 264 242 264 0.98

7 9 0.0088 0.61 11.0 0.1 1 23 270 293 270 293 0.95

8 9 0.00021 0.015 16.1 8.8 1 23 307 329 307 329 0.98

9 9 2.7e-06 0.00019 22.0 1.9 1 23 335 358 335 358 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0038	0.26	12.1	0.2	1	23	98	121	98	121	0.95
2	9	7.6e-08	5.3e-06	26.9	4.3	1	23	127	149	127	149	0.97
3	9	1e-05	0.00071	20.2	0.3	3	23	157	177	155	177	0.96
4	9	8.6e-05	0.006	17.3	2.7	1	23	183	206	183	206	0.96
5	9	1.3e-06	8.8e-05	23.1	0.8	1	23	214	236	214	236	0.98
6	9	0.00034	0.023	15.4	6.5	1	23	242	264	242	264	0.98
7	9	0.0088	0.61	11.0	0.1	1	23	270	293	270	293	0.95
8	9	0.00021	0.015	16.1	8.8	1	23	307	329	307	329	0.98
9	9	2.7e-06	0.00019	22.0	1.9	1	23	335	358	335	358	0.96

Sequence Information

Coding Sequence: ATGAATTTTCCTCAAAATTGTTGCGTTTGCTGGCAAAACGGCGTCGATTTCTCGAAAATTTCCTCAGGCAACGTCGAAAAGCCGGAAATCCTTTCAAAATTACGCCAATGCGTCCCGGAATTAGATTGGGACGAAAATTTCGTCATTTGCCCCACATGTAGTTCCGATTTAAACGTAATTCACTCTTTTCGTCTCAAGTGTTTGGAAACAGAAACAATTCGAAAACTACAATCGGAAATTTCAACGAATGAAATTTTGGATACCGACCCCCCTTGTGACGATAATTCCCGCTTTTCTTGTGATTATTGCAACAACAATTTCGTTAACGTCAAGGAATTAGTGTTACACGTTAAAGAAGAACATAAAGGGAATAAACCGTTTTGTTGTAAAATTTGTGGTAAAACTTTTGCTAGATCTTCGAATCTTAGACAACATTTAAAATATCACGACGGTAATAGGACACAAATTTGTACTTTTTGCGGTAAAAGTTATATAACTAAAAGCGATTTAATTATGCATGAAAAAATACATTTAAATAAACGAGAATACAATTGCGATATTTGTTTAAAAAGTTTCAATACTTGTCGTAATTTAAGATCGCATAAACTTGTTGTACATTCAGATCCGGCTACATGGAATTTTGTTTGTAGTGTTTGCGGTAAAAGATTTCCGATTAAATCAAATTACGATAGTCATATGAGACGGCATAATGACGATCGACGTTTTTCTTGTCATTTGTGTGAAAAGAAATTTATCGATAAATGCGTTTTGCAAAGACACTATCGATCACATTCTAATGTTAGATCGTTTTCGTGTAGTGTTTGCGGAACCGAATATAAAGATAGGGGAGTTATGGGGATTCATATGGCGAAAATTCATGGTATTGGAGATGTTAAAGTGCCACTGAAAGTCAAGAATTATTTTTGTCATATTTGTCCTAAATCGTTTTGTGCTAAGAATAAGTTAACGCGACATTTGTGTACTCATACCGGGGAAAAACCGTTCTTTTGTGTTGAATGCGATAAGAAATTTACTGATGTTTCTTACCTCAATCAACACATGAAGAAGACTCATAATGTTGTCGATAACGAAACAAATTAA
Protein Sequence: MNFPQNCCVCWQNGVDFSKISSGNVEKPEILSKLRQCVPELDWDENFVICPTCSSDLNVIHSFRLKCLETETIRKLQSEISTNEILDTDPPCDDNSRFSCDYCNNNFVNVKELVLHVKEEHKGNKPFCCKICGKTFARSSNLRQHLKYHDGNRTQICTFCGKSYITKSDLIMHEKIHLNKREYNCDICLKSFNTCRNLRSHKLVVHSDPATWNFVCSVCGKRFPIKSNYDSHMRRHNDDRRFSCHLCEKKFIDKCVLQRHYRSHSNVRSFSCSVCGTEYKDRGVMGIHMAKIHGIGDVKVPLKVKNYFCHICPKSFCAKNKLTRHLCTHTGEKPFFCVECDKKFTDVSYLNQHMKKTHNVVDNETN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -