Basic Information

Insect: Pyrochroa serraticornis
Gene Symbol: ZFX
Assembly: GCA_905333025.1
Location: HG995158.1:17242960-17245431[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0021 0.15 12.9 7.2 2 23 212 233 211 233 0.97

2 11 4.7e-05 0.0033 18.1 3.1 1 23 239 261 239 261 0.98

3 11 1.5e-05 0.001 19.7 1.8 1 23 267 289 267 289 0.98

4 11 7.9e-05 0.0055 17.4 0.2 1 23 295 317 295 317 0.98

5 11 0.0032 0.22 12.4 1.1 1 23 324 346 324 346 0.99

6 11 0.0012 0.084 13.7 0.4 1 20 352 371 352 375 0.91

7 11 0.00013 0.0092 16.7 5.8 1 23 381 404 381 404 0.95

8 11 0.00027 0.019 15.7 0.1 2 23 414 435 414 435 0.97

9 11 4.2e-06 0.00029 21.4 0.5 1 23 441 463 441 463 0.98

10 11 6.9e-06 0.00048 20.7 1.1 1 23 469 491 469 491 0.95

11 11 1.4e-06 0.0001 22.9 0.5 1 23 497 519 497 519 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0021	0.15	12.9	7.2	2	23	212	233	211	233	0.97
2	11	4.7e-05	0.0033	18.1	3.1	1	23	239	261	239	261	0.98
3	11	1.5e-05	0.001	19.7	1.8	1	23	267	289	267	289	0.98
4	11	7.9e-05	0.0055	17.4	0.2	1	23	295	317	295	317	0.98
5	11	0.0032	0.22	12.4	1.1	1	23	324	346	324	346	0.99
6	11	0.0012	0.084	13.7	0.4	1	20	352	371	352	375	0.91
7	11	0.00013	0.0092	16.7	5.8	1	23	381	404	381	404	0.95
8	11	0.00027	0.019	15.7	0.1	2	23	414	435	414	435	0.97
9	11	4.2e-06	0.00029	21.4	0.5	1	23	441	463	441	463	0.98
10	11	6.9e-06	0.00048	20.7	1.1	1	23	469	491	469	491	0.95
11	11	1.4e-06	0.0001	22.9	0.5	1	23	497	519	497	519	0.98

Sequence Information

Coding Sequence: ATGGAATCGTACACAGAATACGAAGACATACAAATCGAGGAAGTTTGCAGGATTTGTCTTACAAAAAAGGATCAAATGAGCCTAATTTATGAGGCAGGACTAGCGGATATGCTGTTAGAATGTGCATCTGTACAGGTAACCCCAGAAAATGGTCTCTTCAATTTAGTTTGCAATCATTGTGAAAACGAAGTGAGTCGCTGGTACGTCTTTAAACAACAAGTGGTAAGATCTTTTGAAATTGGAAAATGGTTGTTGGATAGAAAACTAAAAATTTGCGAAACTGCAACGTTTAACTCTTCACATCAAAAAACTCAAGAAGAAACTTCTAAAATTTCAATACAATATCCAAATTCGATTGGTGAAAATGTAGAGAAGCTGAAATCTTTACTTGAAGAACATAAATCCACTTCCAAAGACCTACAAGTATTAGAGGATGATAAATTCGAAATATCGTTATGCAGAACTTTGGGTTCTCTTGAAAAAATCGCTGCATCCGACTCGAAGGACCTCCAAACTACAAGTGATTCTAACGTTAACGGCAACAACGACAAAAGCGGTATGGAGGAAATTCATCGAATTATTGACGATACTTCTCAAAATGAAGTGAAAAAGGAGAAAATTCCTGAAAACTTACATTGTAAAATTTGTAACAAACGGTGTACTTCCACAAATTCGTACAACCGTCATGTGAGGACTCACGACGATACTCGACCTTACGTTTGTTGTAAATGTGATAAACCTTTTAAAACTTCACAAGTGTTATCTGAACATATGAAAAGACACTACGATGATAGAAGACACAAGTGCGAGTTGTGCGGTCAAAAATTTTACGCTAAAGCAAGTTTAACGGATCATATGCGCAGTCATACAGGGGAAAAACCGTTCAAGTGCGATATTTGCGAAAGGTCCTTCGGAACGAAAGCAATTTTAAGGCAGCACATGGCGGTTCACACCATGCGAGAGAAGAAGTACCAATGCGAGATTTGCAGCAAATTTCTTCTAACTTCCGGCAGTTTGGAAACCCACAAACGTAAACACTCAGGGATCAAACCTTTTTCTTGTGCCGGCTGCGATAAACAATTTTTCACTAAAGAAGCTATGCAACGACATTTTGGTGCTATTCATGACATCGACAACAACTTTTTATGTAGCGTTTGTTCTAAAGTTTGTTCAACTAAAGTTCATTTGAACAACCATATGAAAAAAAAACATCTCGGATTGGGGCGACCCTCAAATGCAGTTTGTGTTGATTGCGGAAAACAATGCGGGTCAGCTGCAGAGTTGAAAGTACACGTAAGGGTGCACACTGGTGAAAGACCTTATGTGTGCGATATTTGCGATAAAAGATTCATTGCGAAAGGAAATTTAAACTCGCATAAACAACGGCATACGGGCAGAAGGCCGTTTCTTTGCAATCATTGCGGGAAGGCTTTCGGGGAGAAGTCTACGTTGAAAGTTCATGAAAGGATACATACTGGAGAACATCCGTACAAGTGCAACGTTTGCGCTAAAACGTACGTACAGAGTAGCGCGCTTAGAACTCACATGAAAGCGCATTGGAAACAAAATCCAAAGTATTGA
Protein Sequence: MESYTEYEDIQIEEVCRICLTKKDQMSLIYEAGLADMLLECASVQVTPENGLFNLVCNHCENEVSRWYVFKQQVVRSFEIGKWLLDRKLKICETATFNSSHQKTQEETSKISIQYPNSIGENVEKLKSLLEEHKSTSKDLQVLEDDKFEISLCRTLGSLEKIAASDSKDLQTTSDSNVNGNNDKSGMEEIHRIIDDTSQNEVKKEKIPENLHCKICNKRCTSTNSYNRHVRTHDDTRPYVCCKCDKPFKTSQVLSEHMKRHYDDRRHKCELCGQKFYAKASLTDHMRSHTGEKPFKCDICERSFGTKAILRQHMAVHTMREKKYQCEICSKFLLTSGSLETHKRKHSGIKPFSCAGCDKQFFTKEAMQRHFGAIHDIDNNFLCSVCSKVCSTKVHLNNHMKKKHLGLGRPSNAVCVDCGKQCGSAAELKVHVRVHTGERPYVCDICDKRFIAKGNLNSHKQRHTGRRPFLCNHCGKAFGEKSTLKVHERIHTGEHPYKCNVCAKTYVQSSALRTHMKAHWKQNPKY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01330016;
90% Identity: -
80% Identity: -