Basic Information

Gene Symbol
-
Assembly
GCA_963924145.1
Location
OZ001672.1:9781670-9783383[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.00016 0.027 16.8 0.5 1 23 84 106 84 106 0.98
2 9 0.00093 0.16 14.3 0.0 3 23 133 154 131 154 0.92
3 9 0.69 1.2e+02 5.3 0.4 6 23 181 199 178 199 0.96
4 9 0.00049 0.083 15.2 0.9 3 23 207 228 206 228 0.98
5 9 3.4e-05 0.0057 18.9 1.1 3 23 235 256 234 256 0.96
6 9 0.043 7.2 9.1 3.2 1 23 262 285 262 285 0.97
7 9 0.00062 0.11 14.9 1.9 2 23 292 314 291 314 0.95
8 9 0.0017 0.3 13.5 0.9 1 23 320 342 320 342 0.95
9 9 0.00037 0.062 15.6 0.8 1 23 348 371 348 371 0.92

Sequence Information

Coding Sequence
ATGAGCATCCGCTGCTgtcactctaatgtgaaggcgcacttagtcaactGGAAACTTAGAGGTGGCCAGAAGGCTTCAAAAAACGCTACAACGTCCCAAAAGCGCAGTGAAGACGTTCTCTTCGGCAATCCACGAGCGGTGGCTAAACCAATCGTGACAgctaaggaaaaactaaaaataatgcgGCAGAATGTACTTGAGGTCCTTAGGAACTCAACTGTCATGCCATTTAGATGGCTTAAAAGTTCCTACAGATGTTTTTACTGTTACGAAATCTTCCAAGATGCGTCAGATTTAAAAGGACACCAGCAGATACATTTAGGAGACGAAATTAAGCAGCAAACTATGAATAACTATTGGGAGACGGTTGTCTACGTTGATATATCTAACTTAGCGTGCAAACTATGCCCGGAAAattttacaaatctttatgaaCTTATTGATCATTTGATCGCTCAACATGGGGTGATATACAACAAAGATGTTGGCTTATGCATGGTTGCTTTCAAGCTTGATAACTTAAGTGTCAGTTGCATAGCGTGTGGGGCGAGCTTTTATACATTTGGACCCTTATTGCATCATACGAATAAAGACCATAAAGGAACATCGGCAATTCTTTGTGATGTATGCGGGCAGCACTTTAAAGATGTGAACCTTCTTAAAGCCCATTTTAAGACTATCCATGAAAACACTGGTCTTCTCTGTCCAGAGTGCGGAGAAAAATTTGAGACTCGATCGAAATTGACTACACATAAAAAGAACCAACACGAGATTGACAAGGATTATAAATGTCTGGTCTGTTCTTTGACGTTTCAGAGTCATTATAAACGTTCAAGGCACATGGCATCGGAGCACAAGAATCGGCAGGAGATCAAATGCCTGCACTGTCCGAAGACCTTTGTTTTCAGAAGCATGATGATGACACATGTGCGCGACACACATCTGAAAGTGCGTAATTACGTGTGCAGCGTCTGTGGATGGAAAGCATTCAACAGAAATAGACTGAAGAACCACATGTATAAACACAGTGGCGAGAAAAATTTCAAATGTGACGGGTGTGATAAAGCGTTTACGACTAAGAAGATTATGAGAGCACATTTTCTTCGAATACACAAGAACACTCAGCCGCCTGTATTACCATATGATGCTATTAACCCTTATACAGGACATTAA
Protein Sequence
MSIRCCHSNVKAHLVNWKLRGGQKASKNATTSQKRSEDVLFGNPRAVAKPIVTAKEKLKIMRQNVLEVLRNSTVMPFRWLKSSYRCFYCYEIFQDASDLKGHQQIHLGDEIKQQTMNNYWETVVYVDISNLACKLCPENFTNLYELIDHLIAQHGVIYNKDVGLCMVAFKLDNLSVSCIACGASFYTFGPLLHHTNKDHKGTSAILCDVCGQHFKDVNLLKAHFKTIHENTGLLCPECGEKFETRSKLTTHKKNQHEIDKDYKCLVCSLTFQSHYKRSRHMASEHKNRQEIKCLHCPKTFVFRSMMMTHVRDTHLKVRNYVCSVCGWKAFNRNRLKNHMYKHSGEKNFKCDGCDKAFTTKKIMRAHFLRIHKNTQPPVLPYDAINPYTGH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00325871;
90% Identity
iTF_01279621;
80% Identity
-