Basic Information

Gene Symbol
ZNF131
Assembly
GCA_963924575.1
Location
OZ004622.1:4225190-4228321[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.23 13 7.3 0.8 2 23 207 228 206 228 0.95
2 13 0.22 13 7.3 0.8 2 23 304 325 303 325 0.95
3 13 0.76 45 5.7 1.3 2 23 401 422 400 422 0.95
4 13 4.6 2.7e+02 3.2 1.0 2 23 600 621 599 621 0.94
5 13 0.089 5.2 8.6 7.6 1 23 667 689 667 689 0.98
6 13 1.6e-05 0.00094 20.4 2.0 1 23 698 720 698 720 0.97
7 13 0.0077 0.45 12.0 0.2 1 23 726 748 726 748 0.98
8 13 0.17 10 7.7 3.4 1 23 754 776 754 776 0.94
9 13 3.1e-05 0.0018 19.5 0.8 1 23 826 849 826 849 0.97
10 13 0.00022 0.013 16.8 1.5 1 23 853 875 853 875 0.96
11 13 0.0064 0.37 12.2 3.8 1 23 881 904 881 904 0.97
12 13 0.00013 0.0074 17.6 1.3 2 23 911 932 911 932 0.97
13 13 0.0014 0.082 14.3 1.7 1 23 938 961 938 961 0.98

Sequence Information

Coding Sequence
ATGTTGCGGAGTGAAATTATCTCAAACCTGTTTGAAGAATTCGACACAATTTGCAGGTTATGCTTGTGTCGAAGCAAAAAGTTGAAAAGCATCTTCGAGCTCCAGTATGATAAGATTCTGGTCGATGTGGCCAAAATTCAGGTGGAACCGGATGATCAACTTCCAAAGAAAATTTGCGTCCGTTGCAGCGACAAGATCAAGGATATTATTTCTTTTATAAGTCAATGCTCTACTTGTGAAGAAACTTTAAAGGAAATCGAAATGGAATACAGATGGAAACATGGTAATTTTCAAGATGAAATGGAAGATTTCGTGGTAAGTGAGGAGATCGATATAAAGGAATGCACGATTGTAAAAAGTGAAGAGATGTGTGAACCTTTTGAAATCAACACTGAAGCTGGCTCTTCGAATGATTTTGATAACACAATATCAACATCAAAAGAACTAGAAGGTTCAGTTGTAATTCCTGGAAGCCCTGATTCTTCTTATGTGCTTGATGATAAAATTACAAAAGAACCTGTAAAAGAGACTAGAATGGTTTGTGTTAATTGTGGTGAAATTATTAGCTGTTTAAAAGTTCACTATAAACTTGAACCCAAGTGTAAACCAAGAGTTTTGAAGTGTGACATATGTCAGTTTGAAACCAGCAAGAAGTTAGAACTGCAACTTCACAAGCAAGAACATTTGAAAACTGTAACTGATAAAGAAAAGAAACAGAAGGAGGATGGGCAATCTGATTTAGATGTAGATTTTATAGAATCAGTTGAATCAGTTCCTAACTTTGTCCCTGGTGAAATcatgaaaaaatatgtaaaaaagaCTGGAAAGATCTGTCAAAGCAGTAGTGAAATTTCTAACTTGTTAACAGTTCCCTATCAACCTGCACCCAAAAGTACGTCAAAAACCTTGAAGTGTGAAATATGTCAATTTGAAACCAGCAAGAAGCTGGAACTGCAACTTCACAAACAAGAACATTTGAAAGCTGTAACTGATAAAGAAAAGAAACAGAGGGAGGATAAGCAAGATTTTATAGAATCAGTTTGTATGACTGATGTTGAATCAGTTCCTAACTTTGTCCCTGATGAAATcatgaaaaaatatgtaaaaaagaCTGGAAATATCTGTCAAAGCAGTGGTGAAATTTCTAACTCATTAACAGTTCCCTATCAACCTGCACCCAAAAGTACGCCAAAAACCTTGAAGTGTGAAACATGTCAATTTGAAACCAGCAAGAAACTGGAACTGCAACTTCACAAACAAGAGCATTTGAAAACTGCAgcagatacagaaaaaaaacaGAAAGAGAATGAGGAATCTGATGTAGATGAAGATTTTATAGAATCGGATTATATTACTGACGTTGATTCGGTTCCTACTTCTGTGCCTCAtgaaattatggaaaaatctgtaaaaaagaCTGGAAAGACTTGTCAAAGTGGCGATGAAATTGTTAATTCTTTAGCAGTTCATTGTGAACCTGAACCcaaatgtaaaacaaaaaccTTAAAGTGTGAAATATGTCAATTTGAAACCAGCAAGATACTAGAAATGCAACTACACAAACACGAAGATTCCACAACTGTAACAgataaagaaaaacaaaaatctgaTGCAGATGAGGATTCTTTAGAATCAGTTAATATTCCTAGTAATGCTGATTCGGTTTCTCCTCCGCCTGATGAAACGAtgaaaaaatctgtaaaaaagtCTAGAAAAATTTGTCAAAGCTGTGGTGAAATTGTCAACTCTTTAACATTTCACTACCAACTGGAACCAAAATGTAAACCAAAACCTCTAAAATGTGAAGTGTGTCAATTTGAAACCAGCAAGAGACTAGAAATGAAACTCCACAAACAAGAACATCCTAAAACCTCAACCGACAAAGAACAGAAACAGAAGAAAAAGCCGAAACAAGGTAGGACATGCCCGTCCTGCAGTGAAACAGGTTTGATTCTAAGAGACCATTGGAAAGAGAACCCTTACTGCGTACCCAAAAAACACAAATGCCAACACTGCGAGTACAAGACGGCTTCTAGAAAGAAATTTAATACCCACCAGCGTGTTCACTTGGAAAAGGGTTCTTACGAGATGTTCATTTGTCACATTTGCTCCAAAGAGTTCAAATATGAAACCAATTTGAAACGACATCTAGCGGTTCATGAGAATCCTAAACGCTTCGTTTGTGAGTACTGCGGGATTGGCAAGTCGACCAATTTTGAACTGACTGAGCATATCAACAAACATTTTGACAAACGCGAGTTTCTGTGTGACCATTGTGGGGCGAGCTTCCACTCGAAACTCGTGCTAACTGTCCACAAAAGTAAGCACGAAATCAAGGAATGTGGTAAAAGAACGGCGGGAGGCAGCAAAATTTATAAAAGCTTCCAATGTAACTTGTGTGAAAGGTGGCTTTTGGGTAAACCGAGCCTAAAGTATCACATGAGTTTTCAGCATGGGGTGGAACAGAAGGACAAGTATACCTGCCACAAATGCCCAGAAGAATTCACAACTCTTGTCCAGTTGAAGGCACATGTCACTACAGTGCATTGGAAGAAACATTTCTGTAGTTTCTGCGGTAAGACGTTCCAGAATGCTACAGTTCTGGAAGTACATATTCGGAGTCATACTGGTGAGAGGCCGTTTTCCTGCGCTCAGTGCATGCAGAAGTTCCGTCAAAAAGAACATTTAAAAACTCACTTGAAATCTGTTCATAACGGCGGTGCAAAAGCCGAATGCCACATATGTAAAGGTATATTTACCACCAAATGGAATCTCTTGATACACATGAGACAGCATACTGGTGAAAGACCGTATGAATGTCATATCTGTACTAAGAGATTTTACGCTGCAAACAACAGGAAAGCGCATGTGAGGAGGGCTCATGGTGAGAAAGAAGTTAGTAAAATTACTCAGTTCCTTGGGCAGGGGCCTGTCCCTGATTATTCTTTGGATACTTAA
Protein Sequence
MLRSEIISNLFEEFDTICRLCLCRSKKLKSIFELQYDKILVDVAKIQVEPDDQLPKKICVRCSDKIKDIISFISQCSTCEETLKEIEMEYRWKHGNFQDEMEDFVVSEEIDIKECTIVKSEEMCEPFEINTEAGSSNDFDNTISTSKELEGSVVIPGSPDSSYVLDDKITKEPVKETRMVCVNCGEIISCLKVHYKLEPKCKPRVLKCDICQFETSKKLELQLHKQEHLKTVTDKEKKQKEDGQSDLDVDFIESVESVPNFVPGEIMKKYVKKTGKICQSSSEISNLLTVPYQPAPKSTSKTLKCEICQFETSKKLELQLHKQEHLKAVTDKEKKQREDKQDFIESVCMTDVESVPNFVPDEIMKKYVKKTGNICQSSGEISNSLTVPYQPAPKSTPKTLKCETCQFETSKKLELQLHKQEHLKTAADTEKKQKENEESDVDEDFIESDYITDVDSVPTSVPHEIMEKSVKKTGKTCQSGDEIVNSLAVHCEPEPKCKTKTLKCEICQFETSKILEMQLHKHEDSTTVTDKEKQKSDADEDSLESVNIPSNADSVSPPPDETMKKSVKKSRKICQSCGEIVNSLTFHYQLEPKCKPKPLKCEVCQFETSKRLEMKLHKQEHPKTSTDKEQKQKKKPKQGRTCPSCSETGLILRDHWKENPYCVPKKHKCQHCEYKTASRKKFNTHQRVHLEKGSYEMFICHICSKEFKYETNLKRHLAVHENPKRFVCEYCGIGKSTNFELTEHINKHFDKREFLCDHCGASFHSKLVLTVHKSKHEIKECGKRTAGGSKIYKSFQCNLCERWLLGKPSLKYHMSFQHGVEQKDKYTCHKCPEEFTTLVQLKAHVTTVHWKKHFCSFCGKTFQNATVLEVHIRSHTGERPFSCAQCMQKFRQKEHLKTHLKSVHNGGAKAECHICKGIFTTKWNLLIHMRQHTGERPYECHICTKRFYAANNRKAHVRRAHGEKEVSKITQFLGQGPVPDYSLDT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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