Basic Information

Insect: Pycnomerus fuliginosus
Gene Symbol: topi
Assembly: GCA_963924575.1
Location: OZ004617.1:11627935-11630050[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.017 1 10.8 1.9 2 21 97 116 96 117 0.94

2 14 1.7e-07 1e-05 26.6 0.4 1 23 142 164 142 164 0.97

3 14 0.043 2.5 9.6 3.3 2 23 171 192 171 192 0.95

4 14 0.097 5.7 8.5 0.2 2 19 211 228 210 231 0.82

5 14 0.0029 0.17 13.3 1.2 2 23 270 291 269 291 0.97

6 14 0.3 18 6.9 0.1 1 19 297 315 297 318 0.83

7 14 0.88 51 5.5 3.0 2 21 334 353 333 357 0.83

8 14 0.01 0.59 11.6 0.1 1 23 474 497 474 497 0.97

9 14 0.082 4.8 8.7 0.2 1 23 501 523 501 523 0.96

10 14 1.5e-06 8.9e-05 23.6 2.4 1 23 529 551 529 551 0.98

11 14 0.042 2.5 9.6 0.2 1 23 557 582 557 582 0.96

12 14 0.09 5.3 8.6 2.7 1 23 588 610 588 610 0.86

13 14 3.9e-05 0.0023 19.2 0.5 3 23 618 638 616 638 0.97

14 14 0.00077 0.045 15.1 1.7 1 23 644 667 644 667 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.017	1	10.8	1.9	2	21	97	116	96	117	0.94
2	14	1.7e-07	1e-05	26.6	0.4	1	23	142	164	142	164	0.97
3	14	0.043	2.5	9.6	3.3	2	23	171	192	171	192	0.95
4	14	0.097	5.7	8.5	0.2	2	19	211	228	210	231	0.82
5	14	0.0029	0.17	13.3	1.2	2	23	270	291	269	291	0.97
6	14	0.3	18	6.9	0.1	1	19	297	315	297	318	0.83
7	14	0.88	51	5.5	3.0	2	21	334	353	333	357	0.83
8	14	0.01	0.59	11.6	0.1	1	23	474	497	474	497	0.97
9	14	0.082	4.8	8.7	0.2	1	23	501	523	501	523	0.96
10	14	1.5e-06	8.9e-05	23.6	2.4	1	23	529	551	529	551	0.98
11	14	0.042	2.5	9.6	0.2	1	23	557	582	557	582	0.96
12	14	0.09	5.3	8.6	2.7	1	23	588	610	588	610	0.86
13	14	3.9e-05	0.0023	19.2	0.5	3	23	618	638	616	638	0.97
14	14	0.00077	0.045	15.1	1.7	1	23	644	667	644	667	0.98

Sequence Information

Coding Sequence: ATGAACATATCTGATGATAAATTGAATTCTGTGATAAGTACCCATTTCATAAGCGACTCTGGTATAATTTCATCCACGAGGTACGAGGAAGATTTCATCAGTCATCAGCTAATATCGAAGACTCCAATTTTATGCGAAGAGGTGCGGCTTAGGGAATTCCTGAACTTCAGCCAGCATTCAATTTTTCGAGAACAGCGCGAAGATTACGTGAAGATATACAAATTCGAAAATCCGAAAGAATTAGAGCAGATAAAGCGCAAACCAAAGCTGAATATACCAAATATGATCAGGTGCCAGAATTGCGAAACCAACTATCCCACCAAATACCAGTACCAAAGACACCAGTGCGAGTTTAACGCCGAAAAAGTTGTGCTTAAACCCAACGCCGATATTTTGGATTTGGACAAGGGAAAGAAGGTAAAGTACGACTGTCCCATCTGCGGAAAGCAATTTGTAAGTAAAAATAACTTAGAAAGACACCAAAGTAGCCACGATAATACCAACGACAACACTTGCGAACACTGTAAAAAACAGTTTGTCAGCGAAAATCGACTTAGAATTCACAAAGAAAACCATTGCAAAAAGGCTGGAGACATTTCCAAATTTTATCGCAGCGATGTTACTGTTtggaaatgcaaaaaatgtcaAGAAGTCTTCTCTTCCAGTACCACCGCGGGGTATCACATTGAATCTTGTGACGAACTGATCGACTGTACAGACATTAAACAAGAAATAAATTCACCAACAGATGATCAAGCCAAAAATGATACAAAAACAATTCTAAAAATTTCTACTGAGATTTTGTTGCAGTGCGAATTTTGCAACCGCACTTACGCCGACAAACAGATCCTCCTCAAACACCAAAAAACTCATAAAACTGACAAAAATTATGAATGCGTAATTTGCAAGGAATCATTCAATTCCTACATAACCGCGTCCCAACACTGGCTCAGGAAATGCTCTGAGAAAGCCAATCTTTTCTACTTACCGAAACTTACATACTGCGAATTCTGTGACCGCACTTTTAAATCCCACGAAATCTTGTACACGCACAAGATAAAAAAGAAGCACTATTCCCCGAAAATGTTCATAAACATGGATTCGGAGATTAAAACCGCAAATGAAACTAAGAATATAAAAAGCGAAGACGTAATTGATAAATTAATTGAAGATGTTTTAATTGCTCTTGAAATACCTATTAATAAGCGcaagaaaaataatgaaatcgcCGAAGAGAATAAAGAAAATATTGATCCCAATGAAGTGGAGATAAAAACGGAGCCGTTAACTCAGACCAGTGAGAATGATGAGAGTAATAATGTGGTGGCGGAAAAAAAGAAAAGGGGAAGAAAGCGCAAGATGCCGAGACCGCAAGTAAAATCGAAAAAAAGCCACAGTTGTCTGGAAAATGGTTTCATGTACCAGTGTGAGAGATGTGTTGAAGTTTTTGAATCCGTTAATGAATTGGAGACTCACCGAGAGAAAGATCATGCTGCCAACTTTAATTGTGATGAATGTGGTCAGATTTTGCACAGCGCAAGGGCGCTTTTAATTCACAGCCGAGCTCATAAAAGTCTTAAACCCTATGTTTGTGATACCTGTGGAAGAAGTTATTCACAAACTTCGCATCTATGGCAACACATGAGATTTCACCAAGGGATAAAACCGTTCGCTTGCCCTCACGAAGGATGCGAAGCGCGGTACACAATCCGACCTGACCTCAAGGATCATATCAGGAAAGTACACACTAGAGAAAGACCCTTCAAATGCAGCGTTTGCGGAAAATGCTTCTTAACCGGCTCGGTTTATTACCAACACCGGTTAATACACACGGAAGACCGTCGTTATGGATGCGATATGTGCGACAAACGCTTTTTCAGAGCCGATGCCCTTAACAACCACAAAAGGATTCACACTAACGAGCGACCTTATCCCTGCTTTGTTTGCGGCAGGCTTTTTCGACAAAAAGGAGATCGAAACAAACATTTCCGAACTCAGCACCCCGACGCAATTTTTAGTTAA
Protein Sequence: MNISDDKLNSVISTHFISDSGIISSTRYEEDFISHQLISKTPILCEEVRLREFLNFSQHSIFREQREDYVKIYKFENPKELEQIKRKPKLNIPNMIRCQNCETNYPTKYQYQRHQCEFNAEKVVLKPNADILDLDKGKKVKYDCPICGKQFVSKNNLERHQSSHDNTNDNTCEHCKKQFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCKKCQEVFSSSTTAGYHIESCDELIDCTDIKQEINSPTDDQAKNDTKTILKISTEILLQCEFCNRTYADKQILLKHQKTHKTDKNYECVICKESFNSYITASQHWLRKCSEKANLFYLPKLTYCEFCDRTFKSHEILYTHKIKKKHYSPKMFINMDSEIKTANETKNIKSEDVIDKLIEDVLIALEIPINKRKKNNEIAEENKENIDPNEVEIKTEPLTQTSENDESNNVVAEKKKRGRKRKMPRPQVKSKKSHSCLENGFMYQCERCVEVFESVNELETHREKDHAANFNCDECGQILHSARALLIHSRAHKSLKPYVCDTCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCGKCFLTGSVYYQHRLIHTEDRRYGCDMCDKRFFRADALNNHKRIHTNERPYPCFVCGRLFRQKGDRNKHFRTQHPDAIFS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -