Basic Information

Insect: Pterostichus niger
Gene Symbol: tfap2e
Assembly: GCA_947425015.1
Location: OX380336.1:26277149-26298007[-]

Transcription Factor Domain

TF Family: AP-2
Domain: TF_AP-2 domain
PFAM: PF03299
TF Group: Basic Domians group
Description: Activator protein-2 (AP-2) transcription factors constitute a family of closely related and evolutionarily conserved proteins that bind to the DNA consensus sequence GCCNNNGGC and stimulate target gene transcription [PMID: 2010091, PMID: 1998122]. Four different isoforms of AP-2 have been identified in mammals, termed AP-2 alpha, beta, gamma and delta. Each family member shares a common structure, possessing a proline/glutamine-rich domain in the N-terminal region, which is responsible for transcriptional activation [PMID: 2010091], and a helix-span-helix domain in the C-terminal region, which mediates dimerisation and site-specific DNA binding [PMID: 199812]. http://www.ebi.ac.uk/interpro/entry/IPR013854
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 6.5e-84 3.5e-79 266.8 0.0 1 196 232 425 232 426 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	6.5e-84	3.5e-79	266.8	0.0	1	196	232	425	232	426	0.98

Sequence Information

Coding Sequence: ATGGGAGCAGTTGGTGATTATGGATTGATTATTGATGGTGCGGTGTGTCGACATTTGAGAATTCCGATTGAAAAAGTTATGGAACGACTGACCGCGGGCCACGGCTCGATAACGCTGAGCAGCGGGTCGCCGGCGTACGGCGGTCACGGGCCGGGTGGACATGGCGGCGGCGGGCGCGGCGGCCAAGGCGCTGGCGGCGGACTCCACGGGTCTATGCAGCACCAGCTTCCGCAGCCCGACTTCCAGCCTCCCTACTTCCCACCACCCTTCCATCACGCACCGCCGCCCAGCCCGCCACCGCAGCAAACCGCGCACGGCGCCGGTCTCGAGTACCTTGCCGATCCCTACGGTGGCCTTGGCGGCCTCCACCACTACAACCAGCTTGGGCTTCGACCGAGGGAACCTGATCCCACCCACGGACATGTGAGCCAGTTAAGCCACGGCGCCAGCTTTCACTATGGTGGCGGTCCTGGAGGCGGCGGCCGACCTGGGGACTACACGCTTGGAGGTACGCCGCAGCGTTTACACGAAGATCCTCTGGCGCTTCATCAAGCGCTGGGCCAGGCTGTGGACGAAGCACAGCAGGCCGGCATGGACGATCAAACCGGCTTCATCACTGACCTGCCATTGCTCAAAAGTATGAAAGGTGGCAAAGACCACGGCGGTGGTGGTATCGCATCTCCCTCCGACGTCTTCTGCTCCGTCCCTGGCCGCCTGTCCTTGCTAAGCTCTACGAGTAAGTACAAAGTTACGGTGGGGGAAGTGCAACGCCGACTCTCCCCTCCGGAGTGCCTGAACGCGTCCTTGCTGGGCGGCGTGCTTCGGCGCGCTAAGAGCAAGAACGGTGGACGCCTGCTGCGCGAGAAGCTCGAGAAGATCGGACTGAATCTGCCAGCGGGTCGTAGGAAGGCCGCTAACGTCACGCTGCTCACCAGCCTGGTGGAGGGCGAGGCGATACACCTAGCTAGGGATTTTGGCTACGTTTGCGAGACAGAGTTCCCGGCGAGACAAGTGGCGGAGTATCTCAGTAGGCAGCATAGTGAGCCGCATGAGACGTATAGGCGGAAGGAACTGCTACAGGCGACAAAGCAGATCACCAAAGAGCTGATGGACCTACTGAACCAGGACCGGTCGCCGCTGTGTAACACACGGCCGCAAATTCTATTGGACCCATCAATTCAGCGCCACCTCACACACTTTTCGCTCATCAGCCATGGCTTCGGTAGCCCAGCTATTGTAGCCGCCCTTACCGCTATTCAGAACTTTCTCAGCGAGTCGCTCAAGCACCTGGATAAGGTGCAGATGGGCGCAGCAGCAGCCGGCTCACATCCGCAGCCCATGGTCGTCACATCGTCATCCGCGCTCGACAAGACCAAGCTCGAGGACAAGAAGTGA
Protein Sequence: MGAVGDYGLIIDGAVCRHLRIPIEKVMERLTAGHGSITLSSGSPAYGGHGPGGHGGGGRGGQGAGGGLHGSMQHQLPQPDFQPPYFPPPFHHAPPPSPPPQQTAHGAGLEYLADPYGGLGGLHHYNQLGLRPREPDPTHGHVSQLSHGASFHYGGGPGGGGRPGDYTLGGTPQRLHEDPLALHQALGQAVDEAQQAGMDDQTGFITDLPLLKSMKGGKDHGGGGIASPSDVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRLLREKLEKIGLNLPAGRRKAANVTLLTSLVEGEAIHLARDFGYVCETEFPARQVAEYLSRQHSEPHETYRRKELLQATKQITKELMDLLNQDRSPLCNTRPQILLDPSIQRHLTHFSLISHGFGSPAIVAALTAIQNFLSESLKHLDKVQMGAAAAGSHPQPMVVTSSSALDKTKLEDKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00902714;
90% Identity: iTF_00028387; iTF_01103954; iTF_00767790; iTF_00469302; iTF_01225340; iTF_00902714; iTF_01039805; iTF_01038910; iTF_01040531; iTF_00766079;
80% Identity: -