Basic Information

Gene Symbol
-
Assembly
GCA_963971405.1
Location
OZ020490.1:30895230-30909351[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 30 0.024 1.6 9.8 0.9 3 23 243 263 242 263 0.93
2 30 0.12 8.2 7.6 0.1 1 21 290 310 290 311 0.94
3 30 3 2e+02 3.3 0.1 3 12 316 325 315 327 0.90
4 30 1.2 78 4.5 1.2 1 23 378 401 378 401 0.97
5 30 0.14 9.4 7.4 0.5 3 23 406 427 404 427 0.94
6 30 3 2e+02 3.3 0.6 1 23 484 508 484 508 0.82
7 30 1.1 75 4.6 0.3 1 23 511 535 511 535 0.83
8 30 0.1 6.6 7.9 0.3 1 23 538 562 538 562 0.92
9 30 0.017 1.1 10.3 0.1 1 23 565 588 565 588 0.95
10 30 0.42 28 5.9 3.0 1 23 591 615 591 615 0.92
11 30 0.002 0.13 13.2 1.0 2 23 619 641 618 641 0.92
12 30 0.73 48 5.2 0.8 1 23 644 668 644 668 0.83
13 30 0.56 37 5.5 0.1 1 23 671 693 671 693 0.94
14 30 0.035 2.3 9.3 0.9 1 23 696 718 696 718 0.96
15 30 0.041 2.7 9.1 0.0 1 23 720 742 720 742 0.98
16 30 0.024 1.6 9.8 0.9 3 23 1004 1024 1003 1024 0.93
17 30 0.12 8.2 7.6 0.1 1 21 1051 1071 1051 1072 0.94
18 30 3 2e+02 3.3 0.1 3 12 1077 1086 1076 1088 0.90
19 30 1.2 78 4.5 1.2 1 23 1139 1162 1139 1162 0.97
20 30 0.14 9.4 7.4 0.5 3 23 1167 1188 1165 1188 0.94
21 30 3 2e+02 3.3 0.6 1 23 1245 1269 1245 1269 0.82
22 30 1.1 75 4.6 0.3 1 23 1272 1296 1272 1296 0.83
23 30 0.1 6.6 7.9 0.3 1 23 1299 1323 1299 1323 0.92
24 30 0.017 1.1 10.3 0.1 1 23 1326 1349 1326 1349 0.95
25 30 0.42 28 5.9 3.0 1 23 1352 1376 1352 1376 0.92
26 30 0.002 0.13 13.2 1.0 2 23 1380 1402 1379 1402 0.92
27 30 0.73 48 5.2 0.8 1 23 1405 1429 1405 1429 0.83
28 30 0.56 37 5.5 0.1 1 23 1432 1454 1432 1454 0.94
29 30 0.035 2.3 9.3 0.9 1 23 1457 1479 1457 1479 0.96
30 30 0.041 2.7 9.1 0.0 1 23 1481 1503 1481 1503 0.98

Sequence Information

Coding Sequence
ATGGCGACGCCTGGAAAACTACCACCGGTAACCCTGGGACGTTTGCTTCCCAAGGATCCTCCAGAGTATATGACTCTTCCAAACTTTGATTATGGAGTCGGGCAAAATGTTAAAttggaaatcgaagtaaaacaAGAAGAACCAATTCAAATGACACTTGACGAATTTGACATGAAGGTATTTACGTTACCTGTGCAGGGAACCCTACTTAGTGATGTTCCCAGTGAACTTGTTTCTAACGTTCCATCATACCTCACGAGAAATGTGAAACTGGAAGCTGAAGTCAAGCAAGAAGGTGATCTCGAAGCCGAACATGTAGATGAAGCTGATAGGACGATTGACTCTTCTCGAGTTTCATCTTACCTTGCATGCAACATTAAAGTTGAATATGATGtcaaagaagaagatgatgaactGTCAATTGATGAACTTGAATTATATTCATCCGTCATACCTGTAGCCGAAGGTACGGTTATTTCCAATGAACTGGTAAATACTTCCAGATCTTCCATAAATCCCGATGATCAAGTAAATTTACAACAAGAAGTCGAAATTCTAAATCAACAAGGAGAAGAAATATATCATGAACTCGATCTTAACACTTCCAGTATATTTCCGCAGCATGCGCAGAGTATTAATGTTTGTAACGAACTAGCGAATCCTTCGCAATCTTGCACTATTCCCGGAAGTCTTAGTGAAATTGGGGATATTCATCCACAAATTCTCTGTACTCTATGTCAGAAACTCTTCTCTAATAGGAGAGATTTAACAATTCACAGTTTGGATCATAACAAATTTTCATGCAAAGTGTGTCATGGTTTCCTAAAAATACCATTTTATGGTACCAGTATAATTCGCAAACTTTTGTATGACTGTGAAGCTTGCGGCAAGAATGGTGTGCAGAAGGAGCACTTAGTTTCACACGTTAAAGATGGATCAAATATCTGCAAGGGTTGTCAACGTTCGTTTGCGAGAGATGCCCTGGCACCGAGATCTCCGAGAATTTTCCCGGTTAAAAACCGGCTAGAACGTATGCGAGTTGTACACAAGAAATTTTCCTATGAATCATGTTCTCACCGATTTTTCACAGAGAAAGACCGGTTGGTACATATGAAATCTGCAAAAAAACCATTTCCCTGCAAATGGTGTTGTCAGGGATTTTTCACGGCAACAGACAAGTTGAAACATATAAGGGTTGCACACAAATCACTTGCGTGCAAATCGTGTTCTCAGCAATTTTTCTTGGCCAAAGACCTGTTGAAACATATGAAAGATGTACACAAACTATTTCCTTGCAAATCGTGTTCTCACCATAGGTTTTTCTCGACAATTGACCTGTTGGAACATATGAAAAATGAACATAAAATATTTCCCTGTAAATTGTGTTCTCCCCATCAATTTTTCATAGCTGAATATCTGTTGGTACATATGCAAGATGTACACGAGCTATTTCCTTGCAAATCGTGTTCTCAGAATAAATTTTTCACGGCTAAAGACCTGATGGAACATATAAAAGATGTACACAAACTATTTCCCTGCAAATCGTGTTCTCAGAATAAATTTTTCACGGCTGTAGAACTGATGGCACATATGAAAGATGTGCACGAACTATTTCCCTGCAAAATTTGTTCTCAGAATACATTTTTCACGGCTGAAGAATTGATGACACATATGAAAGATGTACACCAACTATTTGCCTGCAAATTATGTCCTCTACGGTTTTTCACTGTTGTCGACTTGTTAGAACATATGAAAGATGAACATAAAATATTTCCCTGTAAATTGTGTTCTCAACGTAGATTTTTCAGAGCTGAACATCTGTTCAAACATACGCAAGATGTACACAAACTATTTCTCTGCATGTCGTGTTCCCAGAAGTTTTCCACCGCTAAAGACCTGATGAAACATATGAAAGATGTGCACGAACTATTTCCCTGCAAATCGTGTTCTCAGAATAAATTTTTCACGGCTGAACAACTGATGACACATATGAAAGATGTACACCAACTATTTGCTTGCAAATTATGTCCTCTACGGTTCCTTACAAAAAATGACTTAGTCGGGCATTTAGAAGCACACAAGTCATTTCATTGCAGGTTGTGTCCTAAACGATTTTCTATTGAAGATGAGTTTTTAAGCCACTTGGTAGTACACTTGTTTCCCTGTAAATTGTGCCCTGCACAGTTTGTTGCAGAAAATGACTTGGTTGATCATATGGAAAGACATAAGACTAATAAGGGATTAATCACACAGAAGGGAATTCGTAGCCTTATCCATCTAAACATGGCGACGCCTGGAAAACTACCACCGGTAACCCTGGGACGTTTGCTTCCCAAGGATCCTCCAGAGTATATGACTCTTCCAAACTTTGATTATGGAGTCGGGCAAAATGTTAAAttggaaatcgaagtaaaacaAGAAGAACCAATTCAAATGACACTTGACGAATTTGACATGAAGGTATTTACGTTACCTGTGCAGGGAACCCTACTTAGTGATGTTCCCAGTGAACTTGTTTCTAACGTTCCATCATACCTCACGAGAAATGTGAAACTGGAAGCTGAAGTCAAGCAAGAAGGTGATCTCGAAGCCGAACATGTAGATGAAGCTGATAGGACGATTGACTCTTCTCGAGTTTCATCTTACCTTGCATGCAACATTAAAGTTGAATATGATGtcaaagaagaagatgatgaactGTCAATTGATGAACTTGAATTATATTCATCCGTCATACCTGTAGCCGAAGGTACGGTTATTTCCAATGAACTGGTAAATACTTCCAGATCTTCCATAAATCCCGATGATCAAGTAAATTTACAACAAGAAGTCGAAATTCTAAATCAACAAGGAGAAGAAATATATCATGAACTCGATCTTAACACTTCCAGTATATTTCCGCAGCATGCGCAGAGTATTAATGTTTGTAACGAACTAGCGAATCCTTCGCAATCTTGCACTATTCCCGGAAGTCTTAGTGAAATTGGGGATATTCATCCACAAATTCTCTGTACTCTATGTCAGAAACTCTTCTCTAATAGGAGAGATTTAACAATTCACAGTTTGGATCATAACAAATTTTCATGCAAAGTGTGTCATGGTTTCCTAAAAATACCATTTTATGGTACCAGTATAATTCGCAAACTTTTGTATGACTGTGAAGCTTGCGGCAAGAATGGTGTGCAGAAGGAGCACTTAGTTTCACACGTTAAAGATGGATCAAATATCTGCAAGGGTTGTCAACGTTCGTTTGCGAGAGATGCCCTGGCACCGAGATCTCCGAGAATTTTCCCGGTTAAAAACCGGCTAGAACGTATGCGAGTTGTACACAAGAAATTTTCCTATGAATCATGTTCTCACCGATTTTTCACAGAGAAAGACCGGTTGGTACATATGAAATCTGCAAAAAAACCATTTCCCTGCAAATGGTGTTGTCAGGGATTTTTCACGGCAACAGACAAGTTGAAACATATAAGGGTTGCACACAAATCACTTGCGTGCAAATCGTGTTCTCAGCAATTTTTCTTGGCCAAAGACCTGTTGAAACATATGAAAGATGTACACAAACTATTTCCTTGCAAATCGTGTTCTCACCATAGGTTTTTCTCGACAATTGACCTGTTGGAACATATGAAAAATGAACATAAAATATTTCCCTGTAAATTGTGTTCTCCCCATCAATTTTTCATAGCTGAATATCTGTTGGTACATATGCAAGATGTACACGAGCTATTTCCTTGCAAATCGTGTTCTCAGAATAAATTTTTCACGGCTAAAGACCTGATGGAACATATAAAAGATGTACACAAACTATTTCCCTGCAAATCGTGTTCTCAGAATAAATTTTTCACGGCTGTAGAACTGATGGCACATATGAAAGATGTGCACGAACTATTTCCCTGCAAAATTTGTTCTCAGAATACATTTTTCACGGCTGAAGAATTGATGACACATATGAAAGATGTACACCAACTATTTGCCTGCAAATTATGTCCTCTACGGTTTTTCACTGTTGTCGACTTGTTAGAACATATGAAAGATGAACATAAAATATTTCCCTGTAAATTGTGTTCTCAACGTAGATTTTTCAGAGCTGAACATCTGTTCAAACATACGCAAGATGTACACAAACTATTTCTCTGCATGTCGTGTTCCCAGAAGTTTTCCACCGCTAAAGACCTGATGAAACATATGAAAGATGTGCACGAACTATTTCCCTGCAAATCGTGTTCTCAGAATAAATTTTTCACGGCTGAACAACTGATGACACATATGAAAGATGTACACCAACTATTTGCTTGCAAATTATGTCCTCTACGGTTCCTTACAAAAAATGACTTAGTCGGGCATTTAGAAGCACACAAGTCATTTCATTGCAGGTTGTGTCCTAAACGATTTTCTATTGAAGATGAGTTTTTAAGCCACTTGGTAGTACACTTGTTTCCCTGTAAATTGTGCCCTGCACAGTTTGTTGCAGAAAATGACTTGGTTGATCATATGGAAAGACATAAGGCTTACCAGGCAGAGACCATACTTCTGAATTTAATAATTGCTTTCACTGCTCTTTCTGTACTGCACGCTTTCAAACGCTAA
Protein Sequence
MATPGKLPPVTLGRLLPKDPPEYMTLPNFDYGVGQNVKLEIEVKQEEPIQMTLDEFDMKVFTLPVQGTLLSDVPSELVSNVPSYLTRNVKLEAEVKQEGDLEAEHVDEADRTIDSSRVSSYLACNIKVEYDVKEEDDELSIDELELYSSVIPVAEGTVISNELVNTSRSSINPDDQVNLQQEVEILNQQGEEIYHELDLNTSSIFPQHAQSINVCNELANPSQSCTIPGSLSEIGDIHPQILCTLCQKLFSNRRDLTIHSLDHNKFSCKVCHGFLKIPFYGTSIIRKLLYDCEACGKNGVQKEHLVSHVKDGSNICKGCQRSFARDALAPRSPRIFPVKNRLERMRVVHKKFSYESCSHRFFTEKDRLVHMKSAKKPFPCKWCCQGFFTATDKLKHIRVAHKSLACKSCSQQFFLAKDLLKHMKDVHKLFPCKSCSHHRFFSTIDLLEHMKNEHKIFPCKLCSPHQFFIAEYLLVHMQDVHELFPCKSCSQNKFFTAKDLMEHIKDVHKLFPCKSCSQNKFFTAVELMAHMKDVHELFPCKICSQNTFFTAEELMTHMKDVHQLFACKLCPLRFFTVVDLLEHMKDEHKIFPCKLCSQRRFFRAEHLFKHTQDVHKLFLCMSCSQKFSTAKDLMKHMKDVHELFPCKSCSQNKFFTAEQLMTHMKDVHQLFACKLCPLRFLTKNDLVGHLEAHKSFHCRLCPKRFSIEDEFLSHLVVHLFPCKLCPAQFVAENDLVDHMERHKTNKGLITQKGIRSLIHLNMATPGKLPPVTLGRLLPKDPPEYMTLPNFDYGVGQNVKLEIEVKQEEPIQMTLDEFDMKVFTLPVQGTLLSDVPSELVSNVPSYLTRNVKLEAEVKQEGDLEAEHVDEADRTIDSSRVSSYLACNIKVEYDVKEEDDELSIDELELYSSVIPVAEGTVISNELVNTSRSSINPDDQVNLQQEVEILNQQGEEIYHELDLNTSSIFPQHAQSINVCNELANPSQSCTIPGSLSEIGDIHPQILCTLCQKLFSNRRDLTIHSLDHNKFSCKVCHGFLKIPFYGTSIIRKLLYDCEACGKNGVQKEHLVSHVKDGSNICKGCQRSFARDALAPRSPRIFPVKNRLERMRVVHKKFSYESCSHRFFTEKDRLVHMKSAKKPFPCKWCCQGFFTATDKLKHIRVAHKSLACKSCSQQFFLAKDLLKHMKDVHKLFPCKSCSHHRFFSTIDLLEHMKNEHKIFPCKLCSPHQFFIAEYLLVHMQDVHELFPCKSCSQNKFFTAKDLMEHIKDVHKLFPCKSCSQNKFFTAVELMAHMKDVHELFPCKICSQNTFFTAEELMTHMKDVHQLFACKLCPLRFFTVVDLLEHMKDEHKIFPCKLCSQRRFFRAEHLFKHTQDVHKLFLCMSCSQKFSTAKDLMKHMKDVHELFPCKSCSQNKFFTAEQLMTHMKDVHQLFACKLCPLRFLTKNDLVGHLEAHKSFHCRLCPKRFSIEDEFLSHLVVHLFPCKLCPAQFVAENDLVDHMERHKAYQAETILLNLIIAFTALSVLHAFKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-