Basic Information

Gene Symbol
-
Assembly
GCA_963971405.1
Location
OZ020490.1:28892578-28913039[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 1.9e-07 1.2e-05 25.9 2.0 1 23 69 91 69 91 0.98
2 22 0.0013 0.088 13.8 0.1 1 16 97 112 97 114 0.94
3 22 3.6e-06 0.00024 21.9 1.4 1 23 168 190 168 190 0.99
4 22 0.0016 0.11 13.5 5.6 1 23 196 218 196 218 0.99
5 22 2.4e-06 0.00016 22.4 0.2 1 23 224 246 224 246 0.98
6 22 1.1e-05 0.00076 20.3 2.4 1 23 252 274 252 274 0.98
7 22 6.2e-07 4.1e-05 24.3 1.2 1 23 280 302 280 302 0.98
8 22 2e-05 0.0013 19.5 3.5 1 23 308 330 308 330 0.98
9 22 0.00087 0.058 14.4 11.5 1 23 336 358 336 358 0.99
10 22 7.4e-06 0.00049 20.9 0.3 1 23 364 386 364 386 0.99
11 22 2.3e-05 0.0015 19.4 0.9 1 23 392 414 392 414 0.98
12 22 0.00019 0.012 16.5 3.8 1 23 420 442 420 442 0.99
13 22 1.4e-05 0.00095 20.0 6.9 1 23 511 533 511 533 0.99
14 22 8.3e-06 0.00055 20.7 2.0 1 23 539 561 539 561 0.98
15 22 1.2e-06 7.8e-05 23.4 0.5 1 23 567 589 567 589 0.99
16 22 5.3e-05 0.0035 18.2 3.6 1 23 595 617 595 617 0.98
17 22 1.9e-06 0.00013 22.8 2.5 1 23 623 645 623 645 0.98
18 22 6e-08 4e-06 27.5 0.7 1 23 651 673 651 673 0.99
19 22 1.2e-05 0.00078 20.2 2.4 1 23 679 701 679 701 0.99
20 22 0.00021 0.014 16.3 4.1 1 23 707 729 707 729 0.97
21 22 2.3e-06 0.00016 22.5 1.9 1 23 735 757 735 757 0.99
22 22 1.7e-05 0.0011 19.8 6.9 1 23 763 786 763 786 0.98

Sequence Information

Coding Sequence
ATGGGAGATTCATTTTGTACTGTGGATGTCAGTATGGCTAACTGCGTTAGTGATGgtattaTAGACGATACAATAGTCAAGTGTGAATTGCTATCTGAAGATGAAGTGGAATCAGGGGGCCATGACTATGATAACGGCGCGGGCGAGGAAGAGCCGTACCACCAATGCCCCACACATACGAAAATCCATACGGGAGAGAAACCTTACCCGTGTGAAATATGCCAGAAATGTTTCAAGACTAACAGCGAATTGAAACTGCATATAAAAGTGCATACAGGCGAGAAACTTTACCAATGTCAAATTTGTTCTAAAAGTTTCATTACGAAAGATGAATTGGTCGATTCTGTGGACGCCTCGACCATTGATAGTACTAAAGATTGCTGTGTTGAAGaTGTTAAAGACGCGACCATTGTCAAATGCGAAGTCATATCCGAGGACGAAGAGGAGCCGTTCCAGGTGGAGAAAATTAGTACACGTAGAGAAACAAAGAAGACAACTAGATATAAATGTGATATTTGCTCCAAATCAttcagaaaaaatgaaaaattggtgATTCACGTAAGAAAACATCGAGGAGAGAAACCCTACCAGTGTCAATACTGCTCGAAATACTTCAGTACAAGCAGTTCCCATGCGAGACATACCCGCATGCATACAGGGCAGAAACTATATCCGTGCAATGTGTGTTCCAAAGCTTTCTTCGACAACAGCGGCCTACAGCAGCATCTTCGAATACACACCGGGGAGAAGCCTTTCCAGTGTTCGTACTGCGAGAAACGTTTCAAAACTAACGGCGAATTTCAGTCGCATGTAAAGTTACACACGGGAGATACCCCATACAAGTGTGAAGTGTGCTCGAAGAATTTTAGTTCTAAAAGTAACTTGGTCGTACATACACGGTTACATACGGGAGAGAAGCCTTTCCAGTGTGAGGTGTGCTCGAAGTGTTTTACACGTAATTTGGATTTTCAAAGGCATATTACGATACATACGGGGGAAAAGGCGTATCAGTGTCAATTCTGTACAAAATGTTTCGCTCGCAGATGCCATTTGCAGAGACATACAAAAATGCACACAGGTGAGAAACCGTTCCAGTGTCCGGTGTGTTTGAAAGGCTTCTTTGATAATTCCGCGCTGCAGCAACATGCTCGAACTCATACGGGGGAGAAGCCTTACCCTTGTGAAATATGCGCCAAATGTTTCACGACGAAAGGCGATGTGCTGAGACATGCAAAAACGCACACAGGCGAGAGGCCTTATGAGTGCGACGTGTGTTTGAAACATTTTGTGACCAAATGTAACCTAGTTGCGCATACGAAAACACATACTGGGGAGAAGCCTTTCCAGTTTGAAGACGATCCCCCTCCCTCACCTGACTTAGGCCGCTCTAATACTGAATTTGAAAAGGAAACAATAATTACATGTGAAGTTAAATCAGAAGACGAAACATCACCTGAACAAGACTTGATGCTTCAGGATAGCATCGATACAGCGGACACCAACACCCAAGACAACGTAACGCTCAAACCGTTCCAATGCCCAATTTGTTTCAAATGTTCAACCACCAACACCCACTTGAAGCGACACATGAGTACACATACACaagagaaaccttaccagtgtgaAATCTGCTCCAAATGTTTCGCCACTAGCGGCTATTTAAAAAGCCATAAAATAATACATGCTACAGAAAAGCCCTACGAGTGTAACATTTGCTCGAAATCTTTCGCAAAAAATAGCATGTTAATGTCACATGTAAGAATTCACACTGGGGAGAAGCCGTTCCAGTGTAAAGAGTGTTCCGAGTGTTTCGCGCGAAGTGACAAGTTAAGGTTACACAAGTTAACTCATACAGGCGAGATACTGCATCAGTGTCAAATTTGTTCGAAAGGTTTCGATACCAGTAGTCATCTACAGGCGCATGTGAGAGTCCACACGGGAGAGAGACCTTACCAGTGCCAGGACTGTCCGAAGTCGTTTACTAATGTTAGTAATCTGGTGGCGCATAAACGAACACACAGCGGTGAGAAACCTTACAAGTGTGAACAGTGCTTGAAGTGTTTTACTGTAAGTAGTGCGTTGAAGTCGCATGTGAGAGTCCACactggggagaaaccttaccagtgtatAGTGTGTTTGAAGTGTTTCAGTAATAATGGGCATTTAAGTAGTCATATAAGGACACATACAGGGGAAAAACCATACCAGTGTCAGATTTGCTCCAAGAGTTTTGTTAATTGCGGGCAGTTACAGGAGCATGCGAGAACGCATAGTGGAGATAAGCCTTACAAGTGTGGTGTGTGTAAGAAATGTTTTAGTCATAAGGGCAGTTTAAGGAGGCATTCGAGAAAGGAGCATGCCAGCCTTTAG
Protein Sequence
MGDSFCTVDVSMANCVSDGIIDDTIVKCELLSEDEVESGGHDYDNGAGEEEPYHQCPTHTKIHTGEKPYPCEICQKCFKTNSELKLHIKVHTGEKLYQCQICSKSFITKDELVDSVDASTIDSTKDCCVEDVKDATIVKCEVISEDEEEPFQVEKISTRRETKKTTRYKCDICSKSFRKNEKLVIHVRKHRGEKPYQCQYCSKYFSTSSSHARHTRMHTGQKLYPCNVCSKAFFDNSGLQQHLRIHTGEKPFQCSYCEKRFKTNGEFQSHVKLHTGDTPYKCEVCSKNFSSKSNLVVHTRLHTGEKPFQCEVCSKCFTRNLDFQRHITIHTGEKAYQCQFCTKCFARRCHLQRHTKMHTGEKPFQCPVCLKGFFDNSALQQHARTHTGEKPYPCEICAKCFTTKGDVLRHAKTHTGERPYECDVCLKHFVTKCNLVAHTKTHTGEKPFQFEDDPPPSPDLGRSNTEFEKETIITCEVKSEDETSPEQDLMLQDSIDTADTNTQDNVTLKPFQCPICFKCSTTNTHLKRHMSTHTQEKPYQCEICSKCFATSGYLKSHKIIHATEKPYECNICSKSFAKNSMLMSHVRIHTGEKPFQCKECSECFARSDKLRLHKLTHTGEILHQCQICSKGFDTSSHLQAHVRVHTGERPYQCQDCPKSFTNVSNLVAHKRTHSGEKPYKCEQCLKCFTVSSALKSHVRVHTGEKPYQCIVCLKCFSNNGHLSSHIRTHTGEKPYQCQICSKSFVNCGQLQEHARTHSGDKPYKCGVCKKCFSHKGSLRRHSRKEHASL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-