Basic Information

Insect: Pseudoips prasinana
Gene Symbol: topi
Assembly: GCA_951640165.1
Location: OX621263.1:1481571-1483622[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.012 1.9 11.1 0.3 2 23 192 214 191 214 0.92

2 13 0.019 3 10.4 0.6 1 23 220 243 220 243 0.97

3 13 0.018 2.9 10.5 0.5 2 23 250 271 250 271 0.95

4 13 0.00023 0.037 16.4 1.3 1 20 276 295 276 297 0.93

5 13 4.4 7.1e+02 3.0 3.8 2 23 327 349 326 349 0.91

6 13 1.8 3e+02 4.2 2.8 3 23 386 406 385 406 0.94

7 13 0.00037 0.06 15.8 0.5 1 21 411 431 411 432 0.93

8 13 0.0038 0.62 12.6 0.5 2 20 454 472 453 475 0.93

9 13 1.7e-06 0.00028 23.1 0.1 2 23 483 504 482 504 0.97

10 13 9.1e-06 0.0015 20.9 1.8 1 23 510 532 510 532 0.98

11 13 0.0025 0.4 13.2 3.6 1 23 538 560 538 560 0.97

12 13 3.2e-07 5.2e-05 25.4 4.1 1 23 566 588 566 588 0.98

13 13 3.4e-05 0.0055 19.1 2.8 1 23 594 617 594 617 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.012	1.9	11.1	0.3	2	23	192	214	191	214	0.92
2	13	0.019	3	10.4	0.6	1	23	220	243	220	243	0.97
3	13	0.018	2.9	10.5	0.5	2	23	250	271	250	271	0.95
4	13	0.00023	0.037	16.4	1.3	1	20	276	295	276	297	0.93
5	13	4.4	7.1e+02	3.0	3.8	2	23	327	349	326	349	0.91
6	13	1.8	3e+02	4.2	2.8	3	23	386	406	385	406	0.94
7	13	0.00037	0.06	15.8	0.5	1	21	411	431	411	432	0.93
8	13	0.0038	0.62	12.6	0.5	2	20	454	472	453	475	0.93
9	13	1.7e-06	0.00028	23.1	0.1	2	23	483	504	482	504	0.97
10	13	9.1e-06	0.0015	20.9	1.8	1	23	510	532	510	532	0.98
11	13	0.0025	0.4	13.2	3.6	1	23	538	560	538	560	0.97
12	13	3.2e-07	5.2e-05	25.4	4.1	1	23	566	588	566	588	0.98
13	13	3.4e-05	0.0055	19.1	2.8	1	23	594	617	594	617	0.97

Sequence Information

Coding Sequence: ATGAACGACCTAGACCGCTCATGTCGTTTATGCGCACAATTGAAATCAAATAGTGACCTTGTGGACCTTCAAACTGATAAAGAACTGTGGCGAAATGTTTACAACAAATTATTGCGAATTAACGCTGAAATAGACTACGAAGATGATTCTTTACCTAAATTGATCTGTCTTATTTGTTTGAGATCATTGGATAATGCTTTCCAGTTTGTTACTGCTGTAGAAGATGCTCAGAAaagtttgcaaaatattttattgcaaagGTCCATGCCAGATACTAAAGAATTAATCAATAGGGGcattaaaattgaattagtaGATACAGATACAAGTGAAGACAAAACTACATCAGAACCAGAAGATGTGGCACTTACTACCAATGATCATATTATTGATCCCAAAAACATTGATTTTGATCAAAACCaagatactataaaatataaattggaaTTGGAAACTAGTAGTAGTGATGACAGTTTACCTATAAACAATACACCAAAAAAGCGCAGAAAATTCATTACCATAGCTAGTACTTCATCTGTAGATGTAGAATACACATGGAAAAGCATCAAATGGCAATGTTCTCTTTGCGATGCTATATTTCCAACTTGTGGTGAACTAGTCAAACATTCCATGCAGCTACACAAACGTTGCAACACATATTCATGCACTGATTGTGACAGTAAAAGGCGAAGTCTAGAATATTTCATTGCTCACATACAGAAGGAGCATAAGCCAATGTTGATGAACACTTGCTACATTTGCTTTAAGACTTTAACATCACCATATTTGTATAAGTTGCACATTACTGAGCATTATACAACAGAACATGTGTGTCCCGGATGCAATACATGTTTTTCTACTGTTGAAGAATTAAACAAACATAAAGATACATTTTACAGGTCAAACATTAAATCTACCTCACCAAAGGAACAGGAAGCAGCATCCCAGGCAGTGTTGACATGGGAGCAATATAGCTGGAAATGTTGTGTATGCAAATACCTTTGCCAAAATTCTGAAGAGTTGATTAAACATTCAATGgaatttcataatatttgtAATGCATTTGGTTGCATCGAGTGCAATAAGAGCAGGTTGCAAATCAATCACTACATTAAACATGTGCAGCAACAACACAGAAAATTATTGACACGGTCTTGCTACAAATGTTTTGAACAATTTGATTCattaaagaaaacaaacaaacatagaCAAATACACAATACTTCTGAATTCATATGTCCAGGATGTAACACATGTTTTGATAATATGGAGGAATTAACCAAACATACAGACACATactacaaaaatacaataaggTTACCTGTGCCAAAAGAATTTGAACAAATGTCTGATGGCTTAAGGTGTACCGTATGTAACAAAATTTCAAGCAACAGAAGActtttaaacaaacatttatggATACACACAGAGAGATTGAGAAACATTGTTTGTGACATTTGTGGTAAAGGGTTCTATGACAAGGGCACATTACAATCACACATGTATACACATCAAGACTTGAAGCCTTATAAATGTGAAATCTGCAATACTTCTTTCAAAAGACTTTCCAAACTACGGTACCATGTTGCAAGACATGAAAGGAAAGACTCATTCACATGTGATCTTTGCAATAAAAGTTTTAGTTGTAGAgattacttaaataatcataaaattatcCACTTAAATGAATTACCATATACCTGCGAGACATGTAATAAATCATTCAGACGAAAAGAATTCCTCACCCGCCACATGCGCCAGCACACGGGGATCAGGAACTATACTTGTCATGTCTGTTTAAGAGAGTTTGGCAACTggtctaattataataaacatatgaaactaaaacataaaatggATATGTCAAAGAAGAAACGCGATTCTGATGGCACATATGTTCAAAAAACAAcagaatttaatgaaaatattttgcaaTGGAAGGAGAGACTGTCTGTGCCCAAGAAGTTACGTGGAAGTATAAAGAAGTATCATAAAGGAGAGACAATAACAACGGCACCAAATAATAAGAACCACCAGAACATAGCACAATAG
Protein Sequence: MNDLDRSCRLCAQLKSNSDLVDLQTDKELWRNVYNKLLRINAEIDYEDDSLPKLICLICLRSLDNAFQFVTAVEDAQKSLQNILLQRSMPDTKELINRGIKIELVDTDTSEDKTTSEPEDVALTTNDHIIDPKNIDFDQNQDTIKYKLELETSSSDDSLPINNTPKKRRKFITIASTSSVDVEYTWKSIKWQCSLCDAIFPTCGELVKHSMQLHKRCNTYSCTDCDSKRRSLEYFIAHIQKEHKPMLMNTCYICFKTLTSPYLYKLHITEHYTTEHVCPGCNTCFSTVEELNKHKDTFYRSNIKSTSPKEQEAASQAVLTWEQYSWKCCVCKYLCQNSEELIKHSMEFHNICNAFGCIECNKSRLQINHYIKHVQQQHRKLLTRSCYKCFEQFDSLKKTNKHRQIHNTSEFICPGCNTCFDNMEELTKHTDTYYKNTIRLPVPKEFEQMSDGLRCTVCNKISSNRRLLNKHLWIHTERLRNIVCDICGKGFYDKGTLQSHMYTHQDLKPYKCEICNTSFKRLSKLRYHVARHERKDSFTCDLCNKSFSCRDYLNNHKIIHLNELPYTCETCNKSFRRKEFLTRHMRQHTGIRNYTCHVCLREFGNWSNYNKHMKLKHKMDMSKKKRDSDGTYVQKTTEFNENILQWKERLSVPKKLRGSIKKYHKGETITTAPNNKNHQNIAQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01265077; iTF_01265094;
90% Identity: iTF_01265077; iTF_01265094;
80% Identity: -