Basic Information

Gene Symbol
-
Assembly
GCA_033439095.1
Location
JAVBJF010000100.1:233385-240003[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.0023 0.22 12.5 2.6 1 23 362 384 362 384 0.97
2 19 3.4e-05 0.0033 18.3 3.0 1 23 389 411 389 411 0.98
3 19 0.0032 0.31 12.0 1.0 2 21 422 441 421 442 0.93
4 19 0.005 0.48 11.5 0.5 1 23 447 470 447 470 0.98
5 19 0.26 25 6.0 0.0 2 16 509 522 508 529 0.71
6 19 4.5e-07 4.4e-05 24.2 0.9 1 21 535 555 535 556 0.95
7 19 0.00023 0.023 15.6 0.6 1 23 563 585 563 585 0.98
8 19 0.0002 0.019 15.9 0.2 1 23 595 618 595 618 0.97
9 19 0.0041 0.4 11.7 0.6 2 23 627 649 626 649 0.89
10 19 6.2e-05 0.006 17.4 0.7 1 23 657 680 657 680 0.98
11 19 0.026 2.5 9.2 0.1 2 23 712 733 711 733 0.96
12 19 0.0016 0.16 13.0 0.2 1 20 762 781 762 783 0.92
13 19 3.8e-07 3.7e-05 24.4 1.5 1 23 792 814 792 814 0.98
14 19 0.00025 0.024 15.5 0.2 1 20 823 842 823 844 0.96
15 19 1.8 1.7e+02 3.4 3.0 2 23 847 869 846 869 0.93
16 19 0.00032 0.031 15.2 1.2 1 19 911 929 911 931 0.96
17 19 0.00021 0.02 15.8 4.4 1 23 939 962 939 962 0.97
18 19 0.005 0.48 11.4 1.2 1 23 967 989 967 989 0.96
19 19 0.56 54 5.0 2.0 5 21 998 1014 996 1015 0.92

Sequence Information

Coding Sequence
ATGATTTCCGTTGATTCGATTTTATCAGATGAACACGATTTGACCCAATTGAACGATCTTTGTCGTTTGTGTGGAAGTTTGAAAGACACTTCCGCGCTCATTTTTGACGACGTACATCAGCAACATTACGACGACgttataaatatttatttcagaGACGAATTTAAAATTTGTCGAGACGATATTTTACCTCAAAGAATATGTAGAAATTGTTTAACTTCCGTCGAATCGTGGAACCAGTTCTACATTAATTGCGTCCACGTTAACGAGAAATTTCTACAGATAATCGAGAAATTCGATTTGACTAAAGAAGTTAAGAAAAAACCTAACGATATGAATACCGACAATATAAATAACGACATAGAAGTGATCGAAGTCGGCGTCGAAGGCGATaactacgattttttcaacgatcAAGTTGCCAACGAGTTAGATATTACCAACGTTAAGTTCACTGATTCGTTTCCCGATTCCGGTAATTTTCAAGAGTTCGATAATACGATAGAAGATATAAGTTATTCGAATGATCCTATCGAATCGAGCACCAGTAACCCGCTATCTCCTGATCAACCAGAGTATAACGATGGAAACGAAATCACCGCCGATATTGTAATCGGCGATGACGAGTACGAGGACAGTAAAATCGAAGACGACGATGCCGCCGATGGCGACGAAACCGGCATTGTCGACGCAGATTGCACTGAAAATAGTACGCTGCCTCCGACATCAGTTACCGCTCGCTTACTTGACGAATTACAAGCAGCCTCGAAAAATTCACCGTGTCCATTAATGGTCGAGGACCCCGACTGCACCGAGCTAGATACCGGTATGATTCTTAATTGCGCCATATGTTCAAATACCTCGTTTAGTGGTCAATTGATCGACAACCAATACGTTTGCGAGGCCTGTTGCAATAACATAAAGCTCGAATCGAAAGATGACGATCGATTTATCGACGAATCGGGGGGTTGCGATAGCGCCGACGATTCCACCGTTTGTGTATCCGATAAAATGACGCCGGTCGCAGCGTTGAGCGACGAGGATATCGATTTAACCGCCATGAAAACACTGCCCGACGAAAAATACCAGTGCGCGTTGTGCAACAAGGTGTATTGCAAGAAGAAAAGCATGATCAATCACGTTTTAAATCATAATAAGAAAATATTCACGTGCAGCGTTTGTCAAAGTACGTTTCGTACGCCGGAGCAGCTGAAAAAGCACAAGAAACGTCACATACGTAGAGTAACCAATAATACGCTTATTTATTGCGAAATATGTAAGAAATATTTCAAGACGAAGAAGGGCTTCGCGTACCATCAGCAGAAGATCTGCATTCAATACAAATGCTACATCTGTGACGAGAAATTCTTGGTACATTCGGTGCTCGAGGAACATATGCGTATCGTACACGACGAAGTGAAGAAATCCGCGTCCTTGTTGAACTCCGACCTCGGTCCAGGAGCAGATGACATCTCGAAAACCTCCAGCTCCATTCCAGCCAACGACAACGAAACCGTAATGAGCGTTTGTCCGATTTGCGACAAGGTCGTTACCCAGGCTGTGCTACCTCGCCATATGGTTCTGCATTCCGAAGACAAGCCGTTCACTTGCGACATGTGTGGTAAATCGTTCAAACGCAAGCATTCGCTCCAGGATCACATCATGATCGAGATGGGCATGAAAAACTACGTTTGCGACATCTGCGGAATGAAGTTCCTCAAACAAGGTTACCTCAACAAGCACGTACGATATCATCAACTGAACAACGGCGAATTCCAGGGCTTCCCTTGCGAAAAATGCGGCAAAAAGTTTCCGGAAAAATGGCGCCTAGGAGTTCATCAGCGATCCGTCCACAAAGGAGGTCGATTTTCGTCTTGTAAATGCGACATTTGCGGCAAAGATTTCGCCGAAAGGTGGATGGTGCGGAGGCACAAAGCCGAGGAACACAATGGCGAAGAATTCAAGGAATACAAATGCGACGTTTGCGGTAAAAAGTTCCAAGAGAAGTGGCTGATAAGGGCGCATCAAAGGAGTACCCATAAAGGCGGCGTCAGGAAGAGATACTGCAAGATATGCGGCCGCAGCGATCATCAGCAGGAAGATTGCACTCATCGGCACAACATTCAGAATGTCACCTGTGAACTATGCGGCGACCAGTTCGATTCCAATATCGCTCTCAAGGAGCATATTACCTCGCACGTCGGTTGTTTCGATCGAGTAGCCCAGACGATCAAAGTCGAGGATATGCTGCAGACCAAACCTCAAGGAACCAAGGACGTTCTCCATATTTGTTCCGGGTGCGGTAATCAGTTCTCCAGTAAGGCGCAACTTCGTGATCACGAAATCTCTGCCAACTGCCTTAGCGAGACGAAATACGAATGCGAAGATTGCGGCAAGGTATTCCATTCGAAATCCAGCCTAAGTAATCATTTGATGAGCCATCGCAAAATTGGCATATCGACTACCTTCAAATGCGATTTCTGCGACAGAGAGTTCCGCACCAGCGAAGGCCTCGACAGTCACATGTCCGCCGATAAATACTGCAAAATTTGCAAAGAAGTATACCCGTGCGATGATCACCTGCGAAATCACGTCTATAAAGAgcacgacgacgatgacgaagATGAGAACCAGCAGCCAGAAGTCAAACGATCGCGATTCCAGATTGACGAATCGTCTCCGGATGAAGCAGATGGTAAATCTGTGTCCGGCGCTAAAATCCAGAAATCGTTCGAGTGTAAAATTTGCAACAAAAGATTCGCCAGGAAACAGGCGATGAAGAATCATTTCTACGCCGAGCTGAATTTACGTAATCACGAGTGCGAGTTCTGCGACAAACGGTATAATTACTATTCGCATCTGAAAGAGCATATTATTACCAATCATGGCGAAAAAGAATACTCTTGCGTGTTCTGCGGTAAAGATTTCCCGACCAGGAAACGATTCAGAGATCACGTTTCGTTGCATTCGGAAGATAAACCGTTCCACTGCGAATGCGGACTTTCGTTTAAATTGAATAGATACCTGAGTAAAcataagaaaaaatgtaaatcgatagtgaaaaaagaaattaactAG
Protein Sequence
MISVDSILSDEHDLTQLNDLCRLCGSLKDTSALIFDDVHQQHYDDVINIYFRDEFKICRDDILPQRICRNCLTSVESWNQFYINCVHVNEKFLQIIEKFDLTKEVKKKPNDMNTDNINNDIEVIEVGVEGDNYDFFNDQVANELDITNVKFTDSFPDSGNFQEFDNTIEDISYSNDPIESSTSNPLSPDQPEYNDGNEITADIVIGDDEYEDSKIEDDDAADGDETGIVDADCTENSTLPPTSVTARLLDELQAASKNSPCPLMVEDPDCTELDTGMILNCAICSNTSFSGQLIDNQYVCEACCNNIKLESKDDDRFIDESGGCDSADDSTVCVSDKMTPVAALSDEDIDLTAMKTLPDEKYQCALCNKVYCKKKSMINHVLNHNKKIFTCSVCQSTFRTPEQLKKHKKRHIRRVTNNTLIYCEICKKYFKTKKGFAYHQQKICIQYKCYICDEKFLVHSVLEEHMRIVHDEVKKSASLLNSDLGPGADDISKTSSSIPANDNETVMSVCPICDKVVTQAVLPRHMVLHSEDKPFTCDMCGKSFKRKHSLQDHIMIEMGMKNYVCDICGMKFLKQGYLNKHVRYHQLNNGEFQGFPCEKCGKKFPEKWRLGVHQRSVHKGGRFSSCKCDICGKDFAERWMVRRHKAEEHNGEEFKEYKCDVCGKKFQEKWLIRAHQRSTHKGGVRKRYCKICGRSDHQQEDCTHRHNIQNVTCELCGDQFDSNIALKEHITSHVGCFDRVAQTIKVEDMLQTKPQGTKDVLHICSGCGNQFSSKAQLRDHEISANCLSETKYECEDCGKVFHSKSSLSNHLMSHRKIGISTTFKCDFCDREFRTSEGLDSHMSADKYCKICKEVYPCDDHLRNHVYKEHDDDDEDENQQPEVKRSRFQIDESSPDEADGKSVSGAKIQKSFECKICNKRFARKQAMKNHFYAELNLRNHECEFCDKRYNYYSHLKEHIITNHGEKEYSCVFCGKDFPTRKRFRDHVSLHSEDKPFHCECGLSFKLNRYLSKHKKKCKSIVKKEIN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-