Pinq024560.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Prosopocoilus inquinatus
Gene Symbol
topi
Assembly
GCA_036172665.1
Location
CM069876.1:50749463-50765209[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 47 0.13 8.1 8.1 0.0 1 23 110 132 110 132 0.97
2 47 0.0086 0.54 11.8 0.2 1 23 136 158 136 158 0.98
3 47 0.026 1.6 10.2 2.5 1 23 192 217 192 217 0.96
4 47 0.46 29 6.3 0.5 1 19 223 241 223 246 0.90
5 47 0.021 1.3 10.6 1.3 1 23 253 275 253 275 0.97
6 47 0.62 39 5.9 0.3 2 23 280 300 279 300 0.96
7 47 0.012 0.78 11.3 3.4 1 23 306 328 306 328 0.98
8 47 5.9e-06 0.00037 21.7 4.8 1 23 334 356 334 356 0.98
9 47 0.00077 0.048 15.1 1.4 1 22 362 383 362 383 0.95
10 47 0.079 4.9 8.7 0.0 1 23 482 504 482 504 0.97
11 47 0.0086 0.54 11.8 0.2 1 23 508 530 508 530 0.98
12 47 3.4 2.1e+02 3.6 0.5 1 23 536 558 536 558 0.97
13 47 0.026 1.6 10.2 2.5 1 23 564 589 564 589 0.96
14 47 0.11 6.9 8.3 0.5 1 19 595 613 595 618 0.90
15 47 0.00043 0.027 15.9 1.7 1 23 625 647 625 647 0.99
16 47 0.26 16 7.1 0.2 2 23 652 672 651 672 0.95
17 47 0.11 6.7 8.3 3.3 1 23 678 700 678 700 0.98
18 47 4e-05 0.0025 19.1 4.1 1 23 706 728 706 728 0.98
19 47 0.0022 0.14 13.6 0.6 1 20 734 753 734 755 0.93
20 47 0.079 4.9 8.7 0.0 1 23 854 876 854 876 0.97
21 47 0.0086 0.54 11.8 0.2 1 23 880 902 880 902 0.98
22 47 3.4 2.1e+02 3.6 0.5 1 23 908 930 908 930 0.97
23 47 0.026 1.6 10.2 2.5 1 23 936 961 936 961 0.96
24 47 0.11 6.9 8.3 0.5 1 19 967 985 967 990 0.90
25 47 0.00043 0.027 15.9 1.7 1 23 997 1019 997 1019 0.99
26 47 0.23 15 7.3 0.1 2 23 1024 1044 1023 1044 0.96
27 47 0.00088 0.055 14.9 4.9 1 23 1050 1072 1050 1072 0.99
28 47 5.9e-06 0.00037 21.7 4.8 1 23 1078 1100 1078 1100 0.98
29 47 0.4 25 6.5 0.8 1 13 1106 1118 1106 1119 0.91
30 47 0.022 1.3 10.5 0.2 1 23 1205 1227 1205 1227 0.96
31 47 0.002 0.12 13.8 0.6 1 23 1232 1254 1232 1254 0.99
32 47 2.2 1.4e+02 4.2 0.2 1 23 1260 1282 1260 1282 0.88
33 47 0.0021 0.13 13.7 0.5 1 23 1318 1341 1318 1341 0.94
34 47 0.00088 0.055 14.9 0.7 1 23 1349 1371 1349 1371 0.97
35 47 0.00033 0.02 16.2 0.2 2 23 1377 1398 1376 1398 0.93
36 47 2.8e-05 0.0017 19.6 4.3 1 23 1404 1426 1404 1426 0.98
37 47 8.1e-07 5.1e-05 24.4 2.9 1 23 1432 1454 1432 1454 0.98
38 47 0.15 9.1 7.9 0.0 1 23 1589 1611 1589 1611 0.94
39 47 0.0086 0.53 11.8 0.4 1 23 1615 1637 1615 1637 0.98
40 47 0.0063 0.39 12.2 0.5 1 23 1643 1665 1643 1665 0.98
41 47 0.0079 0.49 11.9 1.3 1 23 1671 1695 1671 1695 0.95
42 47 0.063 3.9 9.1 0.8 1 23 1701 1724 1701 1724 0.94
43 47 1.5 92 4.7 1.1 2 23 1731 1752 1730 1752 0.93
44 47 0.00046 0.029 15.8 0.3 2 23 1758 1779 1757 1779 0.95
45 47 0.00018 0.012 17.0 5.3 1 23 1785 1807 1785 1807 0.98
46 47 1.2e-06 7.5e-05 23.9 2.1 1 23 1813 1835 1813 1835 0.97
47 47 0.00039 0.024 16.0 1.8 1 21 1841 1861 1841 1862 0.95

Sequence Information

Coding Sequence
ATGAGgtGTCAGAATAAGTGGCACGGGAATACCCGAGACACACAGACGGTCAACAATCACACGTTGAGGGGAGGAAAGAATCGGGGGGCAAGCGGAGGACCAAATAATGTTATTGTGAAAGATCACGTGGTTTCTGTGGATGACTCCCCCTCGCACGGTAACAAAGTCAAGAAGCTGCTCCCCGACGAATCCGTGAAGCGTTTCCTGTGCGAATTGTGCAGCGATCCAGAATTAATGACGCTCGTAGAACTGAACCGTCATTATCTGACTCACGGCAAGGTGGGACTGAAGAAGTTCAGGAATCGCCGGTCCAAACCCGATCAGCTGTTCACTTGCGAGATCTGTGCGGAGAACGTGGGTTCCGCGGCGGACCTGGAGAGACACGTCGGCACCCACGAGGATCAATACTCTTGCGACGCGTGCAAAAGAGGTTTCAAGCGCATCATCGACTACATCATCCACATGAAGATCCACGGCGAGGATAACTTCTTTAGGTGCGCCCTCTGTGATTACCGGAACGAGAGCGCTTCGCGCATGCGCCGGCACGTCCTCTGCCACGACCGGTTTAAGAACTATCGCTGCGAAGTCGAAGGCTGCGACAGGACCTTCACGATTTCGACGCACTTCGAGGAGCACAAGAAGTATTTCCACGCGGGTGAAAAACCGTACGCCTGCGAGGTCTGCGGCCTAAAGTTCATGTACGAGCGAGTTCTGAATCGACACGGCGTCGAATGTCACAAAGTCGGTCCGAAGTTATTCAAGTGCAAGAAATGCGGCGAGATCTTCGCCACCTACAACATACGTCGCAACCACATGAAAGTCCACAAGGAGAGCATCGTGTGCGGTGTTTGCGGGAAAAAGGTGGGCGCCAGGCACTACAAGGTCCACGAGCGCATGCACACCGGCGAGAGGCCCTTCAAGTGCGAGCACTGCGGAAAGGCGTTCCCCTGCAAGGCGATACTCAAACAGCACGTGCGCACCCACACCGGATACAGACCGCACAAGTGCGACGTTTGCGGACAGTGTTTCACGCAGCGCTCGAGCTTGGTGAGGCACGTGCGAAGacacaccggcgaaaaaccCTACCCGTGCCACTTTTGCGGCAAAGGTTTCGTCTCCAAgtATCAGAATAAGTGGCACAGGAACACCCGAGACACACAGACGGTTAACAATCACACGTCGAGGGGAGAAAAGAATCGGGGGGCAAGCGGAGGGCCAAATAATGTTATTGTGAAAGATCACGTGGTTTCTGTGGATGACTCCCCCTCGCACGGTAACAAAGTCAAGAAGCTGCTCCCCGACGAATCCGTGAAGCGTTTCCTGTGCGAATTGTGCAGCGATCCTGAATTAATGACGCTCGTAGAACTGAACCGTCATTATCTGACTCACGGCAAGGCGGGACTGAAGAAGTTCAGGAATCGCCGGTCCAAACCCGATCAGCTGTTCACTTGCGAGATCTGCGCGGAGAACGTGGGTTCCTCGGCGGACCTGGAGAGACACGTCGGCACCCACGATGACCAATACTCTTGCGACGCGTGCAAAAGAGGTTTCAAGCGCATCATCGACTACATCATCCACATGAAGATCCACGGCGAGGATAACTTCTTTAGGTGCGCCCTCTGTGATTACCGGAACGAGAGCGCTTCGCGCATGCGCCGGCACGTCCTCTCCCACGACCGCTTTAAGAACTATCGGTGCGAGGTCGAAGGCTGCGACAGGACCTTCACTATTTCGACGCACTTCGAAGAGCACAAGAAGTATTTCCATGCGGGGGAAAAACCGTACGTCTGCGAGATCTGCGGCCTCAAGTTCATGTACGAGCGAGTTCTGAACCGACACGGCGTCGAATGTCACAAGGTCGGTCCGAAGTTATTCAAATGCAAGAAATGCGGCGAGATCTTCGCCACCTACAACATGCGTCGCAACCACATGAAAGTCCACAAGGAGCGCATCGTGTGCGGGGTTTGCGGGAAGAAGGTCAGCACGGATTACTTCAAGATTCACGAGCGCATGCACACCGGCGAGAGGCCCTTCAAGTGTGAGCACTGCCAGAAGGCGTTCCCCTGCAAGGCGATACTCGAACAGCACGTGCGAACTCACACCGGATACAGACCGCATAAGTGCGACGTTTGCGGACAGTGTTTCACGCAACGCTCGAGCATGGTGAGGCACTTGCGAggacacaccggcgagaagccctACCCGTGCCACTTTTGCGGCAAGGGTTTCGTTTCCAAgtATCAGAATAAGTGGCACGGGAATATCCGAGACACACAGACGGTCAACAATCACACGTTGAGGGGAGGAAAGAATCGGGGGGCAAGCGGAGGACCAAATAATGTTATTGTGAAAGATCACGTGGTTTCTGTGGATGACTCCCCCTCGCACGGTAACAAAGTCAAGAAGCTGCTCCCCGACGAATCCGTGAAGCGTTTCCTGTGCGAATTGTGCAGCGATCCTGAATTAATGACGCTCGTAGAACTGAACCGTCATTATCTGACTCACGGCAAGGCGGGACTGAAGAAGTTCAGGAATCGCCGGTCCAAACCCGATCAGCTGTTCACTTGCGAGATCTGCGCGGAGAACGTGGGTTCCTCGGCGGACCTGGAGAGGCACGTCGGCACCCACGAGGACCAATACTCTTGCGACGCTTGCAAAAGAGGTTTCAAGCGCATCATCGACTACATCATCCACATGAAGATCCACGGCGAGGATAACTTCTTTAGGTGCGCCCTCTGTGATTACCGGAACGAGAGCGCTTCGCGCATGCGCCGGCACGTCCTCTCCCACGACCGGTTTAAGAACTATCGGTGCGAGGTCGAAGGCTGCGACAGGACGTTCACGATTTCGACGCACTTCGAAGAGCACAAGAAGTATTTCCACGCGGGAGAAAAACCGTACGTCTGCGAGATCTGCGGCCTCAAGTTCATGTACGAGCGAGTTCTGAACCGACACGGCGTCGAATGTCACAAGGTCGGTCCGAAgttatttaaatgcaaaaaatgcGGCGAGATCTTCGCCACCTACAACATGCGTCGCAACCACATGAAAGTCCACAAGGAGAGCATCGTGTGCGGGGTTTGCGGGAAGAAGGTCAGCGCGAATTACTTCAAGATTCACGAGCGcatgcacaccggcgagaagcccttCAAGTGTAAGCACTGCGGAAAAGCGTTTTCCTGCAAGCCGAAACTCGAAGAGCACGTGCGCACCCACACCGGATACAGACCGCACAAGTGCGACGTTTGCGGACAGTGTTTCACGCAGCGCTCGAGCTTGGTGAGGCACGTGCGAAGacacaccggcgaaaaaccCTACCCGTGCCACTTTTGCGGCAAGGGTTTCGTCTCCAAGTTGGCACCGCCCCCGCCGCCGTTTGAAGTGGCGAAATTCGAGTTCCCGTCGTGGGGCTCCGGCGGTCCGGAAAAGGCGAAACCCAAAAGAATCCGCAAGAAGTGGAAGGAGGACACCGTCGTGAAGACGTACACCTGCGAGATATGCTCGATGACCGCGCAGCTGACCAAGACTGAATTGAACGCTCACTATAAAACCCACGGGAAGGCGCTGGGCTTGAAGAAGTACCGCCGGGGGCCCCCCAAACCCAACCAGATGTTCGCCTGCGAAATCTGCTCGGCGCACTTTTCCTCCGAGGAGGACCTAGACGAGCACCTGCTCAATCACGACGAGAACCAGTACAAGTGCGAGGTATGCGAGAGAGGTTTCAAGAAGATCATCGATTACACCATGCACATGCAGTCACACAACGGCGATAAGCTGTATAAATGCCCCCTGTGCGACTTCAACACCCCCAATGCCTACAAAATTAAGCCGCACGTGCTCTCGCACAATTTCGTTAAAAGATACGAGTGCCCCATCGAGGGGTGCAAGAAGGGCTTTTTAATCTCCACGCATTTCGAGGAACACAAGTATTACCACACCGGCGAAAAACCTTTCGTCTGCGAAACCTGCGGGTTGTCTTTCATGTACAGTCGCTACTTGACCGCGCATCGATTAGGCAAGCACAGCGTCCAAGCCACCAGGGAGTTCCAATGTGAGATTTGTTCGAAGGTATACTCGGGGCAGAGGAGTTACCGCTCGCATTTGCTCGAACACAAGCAGGCCGAGTGGGTTTGCGCGACCTGCGGCAAGACGTTCCGGAAACAAGACGGCCTGAAGACTCACGAGGCGCTGCACGCCGTCGATAAGCCGCATAAGTGCAAGTACTGCGACAAGGCGTTCAACCGGAAGCGCTACTTGGTGGAACACGAGCGCACCCACACCGGTTATAAGCCGTACGATTGCGAGCATTGCGGAAAGAAGTTCACGCAGAGGTCGAGCTTGGTGAGGCACTGGCGCAGTCACACGGGGGAGAAACCGTACACCTGCCGCTTCTGCAACAACGGGTCACGCCCCCTCTTCAAGCTTGAATCGTATCCGAAGATTTCAGCCGGCGCTTATCACTGGAGCCAACTCAACAGATATTTTAACCACGAGGCCCCAAAAAATATCAGCGATGCGAAAGCAGTAACCTACACGAAACGTGAGACCGTTGCGGGTGTCACTTCTTTCATAGATTCGAATGCGAGCCCGAAGAGGGTTCGCAAGAAATGGCCGAAAGACATCGAGGCTAGGATGTACACGTGCGAGATCTGTTTGATGACCGCGTTGTTAACCAGGCCTGAGCTGAACGCCCACTACGACACCCACGAGAACGCCCGGGGGTTGAAGAAGTTCCGGAAGCGCCCCCCGAAACCCGGCCAGCTCTTCGCGTGCGAAATCTGCTCGGCGAATTTCGCAACCGAGGAGGACCTAGACGACCACTTGGTGAACCACGACGACCATTACATCTGCGACGTCTGCCAGAAGGGGTTTAAGAAAATCATCGATTACACCATGCACCTGCAGTCGCATAGCGTCGATAAAATCTACAAGTGCCCCCTGTGCGACTTCAACACCCCCAACGCCTACCACGTCAAGGCGCACGTGCTCTCCCACCAGATCACCAAGAAGTACGAGTGCCCCGTCGAAGGGTGCAAGAAGGGCTTCACGCAGTTCAGCTACTTCCAAGAGCACAAGTATTACcacaccggcgaaaagccgTTCGCCTGCGAGACTTGCGGCGCAGCGTTCATGTACAGTCGCTACTTGTTCTCGCACAAAACAAGGATGCACAAACCGGCCAAGCAGATCATGTGCGAGATCTGCTCGAAGATCTGCGACGGCCGCAGAAACTACCGCCTGCACTCGTTATTGCACGAGAAACCGAAGTGGATTTGCAAGACCTGCGGCAAGACTTTCCGAAAGCAACCGGGCCTGAAGCTGCACGAGAGCATACACAACGGTTACAAGCCGCACAAGTGTAAGTTCTGCGACAAGGCCTTCACCCAGAAGGGCTGCCTGATCGAGCACGAGCGCACGCATACCGGTCAGAGGCCGTTCGATTGCGAGCACTGCGGAAAGAAGTTCACGCAGAGGTCCAGCTTGGCCAGGCACGTGCGCGgacataccggcgagaaaccgcaCGTCTGTCACTTTTGCAACAAGGGATTCACCTCGAAGGCCACCCTCACGTCCCACCTGAAGGCCTGCAAAGGACCttctgattaa
Protein Sequence
MRCQNKWHGNTRDTQTVNNHTLRGGKNRGASGGPNNVIVKDHVVSVDDSPSHGNKVKKLLPDESVKRFLCELCSDPELMTLVELNRHYLTHGKVGLKKFRNRRSKPDQLFTCEICAENVGSAADLERHVGTHEDQYSCDACKRGFKRIIDYIIHMKIHGEDNFFRCALCDYRNESASRMRRHVLCHDRFKNYRCEVEGCDRTFTISTHFEEHKKYFHAGEKPYACEVCGLKFMYERVLNRHGVECHKVGPKLFKCKKCGEIFATYNIRRNHMKVHKESIVCGVCGKKVGARHYKVHERMHTGERPFKCEHCGKAFPCKAILKQHVRTHTGYRPHKCDVCGQCFTQRSSLVRHVRRHTGEKPYPCHFCGKGFVSKYQNKWHRNTRDTQTVNNHTSRGEKNRGASGGPNNVIVKDHVVSVDDSPSHGNKVKKLLPDESVKRFLCELCSDPELMTLVELNRHYLTHGKAGLKKFRNRRSKPDQLFTCEICAENVGSSADLERHVGTHDDQYSCDACKRGFKRIIDYIIHMKIHGEDNFFRCALCDYRNESASRMRRHVLSHDRFKNYRCEVEGCDRTFTISTHFEEHKKYFHAGEKPYVCEICGLKFMYERVLNRHGVECHKVGPKLFKCKKCGEIFATYNMRRNHMKVHKERIVCGVCGKKVSTDYFKIHERMHTGERPFKCEHCQKAFPCKAILEQHVRTHTGYRPHKCDVCGQCFTQRSSMVRHLRGHTGEKPYPCHFCGKGFVSKYQNKWHGNIRDTQTVNNHTLRGGKNRGASGGPNNVIVKDHVVSVDDSPSHGNKVKKLLPDESVKRFLCELCSDPELMTLVELNRHYLTHGKAGLKKFRNRRSKPDQLFTCEICAENVGSSADLERHVGTHEDQYSCDACKRGFKRIIDYIIHMKIHGEDNFFRCALCDYRNESASRMRRHVLSHDRFKNYRCEVEGCDRTFTISTHFEEHKKYFHAGEKPYVCEICGLKFMYERVLNRHGVECHKVGPKLFKCKKCGEIFATYNMRRNHMKVHKESIVCGVCGKKVSANYFKIHERMHTGEKPFKCKHCGKAFSCKPKLEEHVRTHTGYRPHKCDVCGQCFTQRSSLVRHVRRHTGEKPYPCHFCGKGFVSKLAPPPPPFEVAKFEFPSWGSGGPEKAKPKRIRKKWKEDTVVKTYTCEICSMTAQLTKTELNAHYKTHGKALGLKKYRRGPPKPNQMFACEICSAHFSSEEDLDEHLLNHDENQYKCEVCERGFKKIIDYTMHMQSHNGDKLYKCPLCDFNTPNAYKIKPHVLSHNFVKRYECPIEGCKKGFLISTHFEEHKYYHTGEKPFVCETCGLSFMYSRYLTAHRLGKHSVQATREFQCEICSKVYSGQRSYRSHLLEHKQAEWVCATCGKTFRKQDGLKTHEALHAVDKPHKCKYCDKAFNRKRYLVEHERTHTGYKPYDCEHCGKKFTQRSSLVRHWRSHTGEKPYTCRFCNNGSRPLFKLESYPKISAGAYHWSQLNRYFNHEAPKNISDAKAVTYTKRETVAGVTSFIDSNASPKRVRKKWPKDIEARMYTCEICLMTALLTRPELNAHYDTHENARGLKKFRKRPPKPGQLFACEICSANFATEEDLDDHLVNHDDHYICDVCQKGFKKIIDYTMHLQSHSVDKIYKCPLCDFNTPNAYHVKAHVLSHQITKKYECPVEGCKKGFTQFSYFQEHKYYHTGEKPFACETCGAAFMYSRYLFSHKTRMHKPAKQIMCEICSKICDGRRNYRLHSLLHEKPKWICKTCGKTFRKQPGLKLHESIHNGYKPHKCKFCDKAFTQKGCLIEHERTHTGQRPFDCEHCGKKFTQRSSLARHVRGHTGEKPHVCHFCNKGFTSKATLTSHLKACKGPSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-