Pser004456.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Polyplax serrata
Gene Symbol
topi
Assembly
GCA_037055365.1
Location
JAWJWE010000004.1:11104020-11107074[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.081 4.7 7.3 7.0 1 23 211 234 211 234 0.95
2 16 2.7 1.5e+02 2.6 0.8 1 20 245 264 245 267 0.92
3 16 0.079 4.6 7.4 2.1 2 23 317 339 317 339 0.95
4 16 3 1.8e+02 2.4 4.6 1 12 349 360 349 377 0.79
5 16 0.00026 0.015 15.1 1.8 1 23 430 452 430 452 0.96
6 16 9.8e-06 0.00057 19.7 1.2 3 23 466 486 465 486 0.97
7 16 3.1e-06 0.00018 21.2 1.5 3 23 505 525 503 525 0.96
8 16 5.1e-05 0.003 17.4 0.9 2 23 535 556 534 556 0.94
9 16 0.017 1 9.4 0.1 1 23 562 584 562 584 0.97
10 16 0.3 17 5.5 2.8 1 21 591 611 591 615 0.89
11 16 0.18 10 6.2 2.0 2 23 623 644 622 644 0.96
12 16 0.0014 0.083 12.9 0.4 2 23 651 672 651 672 0.96
13 16 0.00096 0.056 13.4 4.1 3 23 680 700 679 700 0.99
14 16 0.00028 0.016 15.1 0.8 1 23 706 730 706 730 0.94
15 16 7.9e-06 0.00046 19.9 3.0 1 23 736 758 736 758 0.98
16 16 0.024 1.4 9.0 6.1 1 23 764 787 764 787 0.95

Sequence Information

Coding Sequence
ATGTGTCAAACATTAGTGACAGTGAACGACTTCAACAACATTTGCAGACTTTGCTTGCAAATTCACGATGAAATGgttgatattttttcttctggaaTAGAAAATCAGTTCatggaaataacaaaattaaagGTCCAGTGTAATGACAAACTTCCACATTCAATCTGTCAAAATTGCAGACAAGAAATGGATTACATAGTTAAGTTTttagaaaaagcaaaaggatCGGATACCTACTTACGTTCAATATTATCCAAAgaagaaagtacaaaaacagATGTAAAAACAATGGGGCAACAACCTAgatcaaaaattgtttctagaaaagcaaaaaaaaaagtaaaagatatATCAGAAAACAACAAACTATATTTGATTGTTGTATCCAAAGGTGAAGCTaattcagaagaagaaaatggaatttgtGTTAAAGATTTAAATGTTGATAATGATGATTTTGAACTGGCCCATTATTGTAAAACAttggtgaaaaattatttttcagaccATACTTATCCTAAGGAATATAACAGTTGTAATGGTGTTGAAAATATGAATCAAAGTATTCCTTTAAATGGCAGCACTAATGAGTCTCATGTAAATTACATGcacaaagttaatttatttatttataaatgcaGAGAATGCAAAGAATGTTTTGATGAGTACTGTGATTTAACACACCATTACTTATTGGTTCATAATGGCGAGTCACCAGAAATAGACTTCTCTTTTATGTGTCCTTTGTGCAAATCTTCCATTGTTGccaaaagtagttttttggCTCATTTAGAATGTCACAAAAAAGATGTCAGTAGTTGTGGAGAACCTttggaatttaatgaaaatgaaaccttttttgtacCACATAAAGAAGCagttgatattattaatatcatgaATACTGACAGTCagtttgaaaaagttattaaagttaCTAACATAAATTCATGTCACATATGTGAATATTCCACAGAATCATTTGGTGCACTCTGCAGTCATTATGAAATGTACCATCCTAAGGATAAGGTACCTGAGGAGACATACATTTGTCCTGTGTGCACCAAAGATTTTAAGACTGATGATTCGAGTAAATCCAAACAAAACTTATACGagcatttgaaaattcataagAATTCAggtatacattttattgaaATTTGGTGTCCCTGTTTGGTTGTGCCTACGGAAATGAACGAGTTGTTGGAATCAGaagaatgtttaaataaaaaccagttCAATAAGAATTCCCAACAGGTGAAGGGAATCTCGCACAACAGTTTAAGTTACATTTGCGAAAAATGCGGTAAGAAATTCTCAAGTGTAATTGCATATAAGAAACATTTCACGAAGCATTCGCAGGGGTCCAACACGTCCTGTGGGAAACGGCCGATTTGCACGATTTGTAATAAGAATTTTGCTAATAAAACGTCACTCTACCGCCATGTAAGAAACCACATAAAAGAAGGAGTTGTAAGCGAGATGGAAACGTCTGAGTTACTGGGAATAATTTGCGAGAAATGTGGGAGAACATTTTCGAATCTCACGAGTCTgacgaaacacaaaaaaagtcaCAGAACCGGAAAAGAGAACACGGCACTTAAGTGCGATATCTGCGGCAGGGAATTCTACAGACAGTCTTCCTTCGACAGACACAAATCGGCTCATTTGAATCCGAAATATTTCGACTGTAACGTCTGCAAACTTCCTCTACCATCCGTCGTCAGCCTTCAGAAGCACTTGGAAATGCACAAAACCAGCAGCAACACTCACGACTGCAAAGCCTGCAAGACCAGTTTCCTTACGAAGGAGTCACTGACGGCCCATCAGACGCACACAGGCCACTACCTCGACCGGAAACCGATGGAATGCAACGTTTGTCACGAGAAGTTCTTCATCGGACGTAAATTCACGGAGCACATAAAAATGCATCCGAAATACAAGATGGGAGAGTGTACTTTGTGCGGAAAACGTTTGTCGACCGTTCAGTCGCTGATGCTTCACATGGGAAGACATTTTGAGTCCAACAGCATTCTGTGCCCCCACTGTGGGAAACAGTTTTTCGAGGAGAGGAACTACCACAGGCATTTACTGACACACGAGGGCATAAAGCCTTTTGCCTGCGACGTGGACGGCTGCGAGAAATCCTTCTACACTCTCTTCGAATTGAACAGACATAAAAAGTACCACAACAATACAAGAGACTTTGTGTGTCCCTACTGTTCAAAGAGTTTTCACGAGGCCAATCATTTGACCGTTCACGTTCGGACTCACACAGGCGAACGTCCCTACGTCTGTCCTCATTGTAACAAAGGCTTCATTACGAGAACGCGATGCAAACACCACATCAAACTGGTTCACCAGGGCATCGGATACGACCTCATACAAAGTAGTATTTCAAAAAAAGTGGCCGTTTTTGAGGCCATCGAAACGGCagtttaa
Protein Sequence
MCQTLVTVNDFNNICRLCLQIHDEMVDIFSSGIENQFMEITKLKVQCNDKLPHSICQNCRQEMDYIVKFLEKAKGSDTYLRSILSKEESTKTDVKTMGQQPRSKIVSRKAKKKVKDISENNKLYLIVVSKGEANSEEENGICVKDLNVDNDDFELAHYCKTLVKNYFSDHTYPKEYNSCNGVENMNQSIPLNGSTNESHVNYMHKVNLFIYKCRECKECFDEYCDLTHHYLLVHNGESPEIDFSFMCPLCKSSIVAKSSFLAHLECHKKDVSSCGEPLEFNENETFFVPHKEAVDIINIMNTDSQFEKVIKVTNINSCHICEYSTESFGALCSHYEMYHPKDKVPEETYICPVCTKDFKTDDSSKSKQNLYEHLKIHKNSGIHFIEIWCPCLVVPTEMNELLESEECLNKNQFNKNSQQVKGISHNSLSYICEKCGKKFSSVIAYKKHFTKHSQGSNTSCGKRPICTICNKNFANKTSLYRHVRNHIKEGVVSEMETSELLGIICEKCGRTFSNLTSLTKHKKSHRTGKENTALKCDICGREFYRQSSFDRHKSAHLNPKYFDCNVCKLPLPSVVSLQKHLEMHKTSSNTHDCKACKTSFLTKESLTAHQTHTGHYLDRKPMECNVCHEKFFIGRKFTEHIKMHPKYKMGECTLCGKRLSTVQSLMLHMGRHFESNSILCPHCGKQFFEERNYHRHLLTHEGIKPFACDVDGCEKSFYTLFELNRHKKYHNNTRDFVCPYCSKSFHEANHLTVHVRTHTGERPYVCPHCNKGFITRTRCKHHIKLVHQGIGYDLIQSSISKKVAVFEAIETAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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