Basic Information

Gene Symbol
-
Assembly
GCA_037055365.1
Location
JAWJWE010000036.1:14343303-14349516[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.14 8.1 6.6 0.8 2 23 103 123 102 123 0.95
2 26 0.0092 0.54 10.3 0.1 6 23 134 151 134 151 0.99
3 26 0.071 4.1 7.5 5.3 1 23 154 177 154 177 0.96
4 26 9.2e-05 0.0054 16.6 4.6 1 23 187 209 187 209 0.98
5 26 0.027 1.6 8.8 3.5 1 23 215 237 215 237 0.97
6 26 0.00066 0.039 13.9 1.2 1 23 243 266 243 266 0.95
7 26 1e-06 5.8e-05 22.8 0.6 1 23 273 295 273 295 0.98
8 26 0.0007 0.041 13.8 3.9 1 23 305 327 305 327 0.97
9 26 0.41 24 5.1 4.9 2 23 334 354 332 354 0.92
10 26 5e-06 0.00029 20.6 2.7 1 23 360 382 360 382 0.96
11 26 4.7e-07 2.7e-05 23.8 0.6 1 23 391 413 391 413 0.98
12 26 1e-06 5.9e-05 22.8 0.5 1 23 421 443 421 443 0.98
13 26 7e-06 0.00041 20.1 2.0 3 23 448 469 446 469 0.95
14 26 0.0012 0.071 13.1 1.9 3 23 597 617 595 617 0.96
15 26 1.2e-05 0.0007 19.4 1.0 1 23 623 646 623 646 0.97
16 26 3.7e-05 0.0021 17.9 1.2 1 23 653 675 653 675 0.99
17 26 0.021 1.2 9.1 3.4 1 23 679 703 679 703 0.88
18 26 6.7e-05 0.0039 17.0 0.1 1 21 709 729 709 732 0.91
19 26 5.9e-07 3.4e-05 23.5 2.5 1 23 742 764 742 764 0.98
20 26 0.00029 0.017 15.0 3.0 1 23 770 792 770 792 0.97
21 26 4.7e-05 0.0028 17.5 1.4 1 23 798 820 798 820 0.98
22 26 0.06 3.5 7.7 0.8 1 23 826 848 826 848 0.96
23 26 0.00084 0.049 13.6 0.3 2 23 855 876 854 876 0.97
24 26 2.3e-06 0.00014 21.6 0.2 1 23 882 905 882 905 0.98
25 26 0.0039 0.23 11.5 3.4 2 23 916 937 915 937 0.97
26 26 1.6e-05 0.00094 19.0 0.6 2 23 944 965 943 965 0.97

Sequence Information

Coding Sequence
ATGATCGCGAGGCGTTCAGCCTGCGACAGAACCTACACGTTACAGGTCAACCTTGAGAAGCTTATGAAAATACCAAGAGTATGGAAaatcCATATATGGAATGGAAAAGACGACTTGGAAACTGACAATTGGATGAGTCTGGGTAAGACGGATGACGAAGATTTAGcgaatgaaaacaattctaAATTAAACGGAGCAACTGTAACCAGCGAAGGAGAGTGCAAAAGTAGACAGAATGTGAAAAGGAGGAAGGGCaacaaaactggaaaaaagaTAAACCGTCCGACCGAGTACAATTACCCGCAGAAGTGTGAATTCTGCGGGCAGGTCTTCCTAGAAAAGGAAATGGTTCGACACAAAAAAGTTCACCCGGAGTCTTTTACCCTGGATTGCATTCCATGTGGGAAGTCATTTAACACAAAAGCCGCTTACGACACTCattataatattcataaaatctACCACTGCTCCGCATGCAAGAAAGACTTTAACGCACGTAAGCACTACCGCAGTCACATGGAACGAATTCACAAGTCAGAGGGAGAAAGGCCCCGGATTCACGAGTGTGACATTTGTAAGAAAACCTTTAAAGACAAATTCGTTTTGAACACGcataaaaaaactcatttcaaCATAAAAGCGCACAAGTGTCCCATGTGCGAGTATGCATGCAACAACCTCACTTACATGCGACAGCACGTTATGAACCACACAAATCAACTTCAGTTCAAGTGCCATATTTGTTACCGGGGATTCATGACCGATTCAGAGCTTCAGGTTCATGTGGACAAGCTGCATGCGAATGAGCCTCAGGTATACAGCTGTAACGTCTGCGGAAAGATCTCGACGAGCAAGGGAAACTTGAGACAACACCAGAAAATACACAACCCGGACCACAACCAGAAAAAAGACCACCAATGTGCCGAATGTGGTAAAACCTTTGCTCTCAAGTGCCGGCTGAAGAAACACGTCCTCTCCCACAAGGGGCAGGACAAGTGTCATTGTAGCATATGTGGAAAGCTCTTGTCGAAAGATTCGTACAAAAAACACCTGAAAGCGCACAGCGGAGAGAGACCCTTTCTCTGCGACTATTGTGGGGAGTCTTTCACTACAAACAGCTGCTTGATGGGACACAGGCGGACTCATACAGGGGAGAAACCCTTGAAACCTTACATTTGTGATCAGTGCGGGAAGAGTTTTGTGCAAAGTTCCACCATGGAAGCTCACAGAAAGACTCATGCGAACGGAACCACAAAGAGCTACTCCTGTGACGAGTGCGGAAGATTGTTCTCTCAAGCCTCTCAACTGACTTCCCACAGAAAGGTTCATGAGACTTTATTTTGTGACATTTGTGGGAAAACATTCACTGATCACTCACTTCTATTCAGCCACACGAATATGTACCATGTACCTGAGAGACCTTACAATTTTATAGGCTTCAACAGTCAGTCCGGACTGTCAGACGGGAAAGATGCCAAAATATTCGGAGAGTGgttggGGAATTCcagtaaaaaaaagacgaaTGCTGTAGTATTAACTGGCACGAGGAACAGTCTAAGGAAAAGAGTTAGAAATCCAAAGTACGCAAACTATAATAATGTATACGAAGTTAATCACAGGAGAAGTTCTTCGTCGCAAGGAAAGAAAGTGGTTTCGTCTGAAACCGAACCAAGAAATTCGGGTGATAATTTTGCAGGAGGTAGGAGTGATGGTACTTATCCATCCAACGTTTCTTCCAGTTTGCCAGAATGCAATAAAAAGAGTCCGGACTCACAGGATGACACTATATGTCACGTGTGTGGGAAGGCAGAGAAGAGTAAGAAACTTTTGAGACGGCATATGGTGAAGCATTCGGACGAGAGACCCTTCTCCTGCAGTCAATGTCCTAAACGGTTCAAAAGGTCCTATGAAGTGAAGGCTCACGTCAAAGTCATGCACGAGACGCAGCAAAAGGACTACAAGTGCGAGGTGTGCGGTCACCAATATGCGATTCGTTCTAAGTTGGAAATTCACATGAGAAGACACAGAAAAGAATACAAGTGTACGTGCCTTGAATGCGGGAAAGGGTTCTATTCAGACTTCAAACTGAAAGAACACTTTTACATACACACGGGAGAGAAACCTTATCAGTGCGAGGTGTGCGGAAGATCGTATGCGTACAAAACCGACCTGATCGCGCACAAAGTGGCTCAGCATCCGGAAACCTGCGACCCCTCTCGCGTCCACAAATGCGAAAAATGCGGAAAAACCTTCTCGACGGCAAAGGCACTCCAGACGCATgagaacacacacacaggggAGAATCTCTTCCCATGCACATTGTGCAGCAAAGTGTGTTCCACgaagaaacttttgaaaagcCACTTGGTCAGGCACACGTCACTCCGTCCATACCCCTGCGACGTGTGTCACAAGACCTTCAAGAGACCTTTCGAAGTGgcaattcataaaaaatcGCATGAAACGGACAAGAAGCACATTTGTGAACTGTGTGGTTACTCGGCCCTTAGAAAGACTTCACTAGATCTGCACATTCGCAGACacaagaaagaatttaaagtaaCGTGCGAGACCTGTGGGAAAGGTTTCTACTCGGACTTCAAACTTCGAGAGCACGTCAACATCCATACGGGTGCGAAGCCTTTCCAGTGTGACATTTGCGGAAAGGGCTACCCGTACAAGTGGAACCTGACCTCCCATAAGCGGATCGCCCACCCCGAAACTTGCGACGCGGACAAAACGCAAAAGTGCGACGTTTGCTGGAAAACGTTTGCCTGTAAGAGAACACTGAAGGAACATATGAAGTTGCACTCAGAGCAAAGTAACAGTACCTGCGACATCTGTGGTAAAACCTTTGCCAAAAGCTCTAAACTGGATCTTCATAGAGAGACTCATGCGTCCGAGGGCCTGACAACGCTTGTTGAACCTGAACAGGAGACAGATCTCATAGaaacaatgaatatttattacttttaa
Protein Sequence
MIARRSACDRTYTLQVNLEKLMKIPRVWKIHIWNGKDDLETDNWMSLGKTDDEDLANENNSKLNGATVTSEGECKSRQNVKRRKGNKTGKKINRPTEYNYPQKCEFCGQVFLEKEMVRHKKVHPESFTLDCIPCGKSFNTKAAYDTHYNIHKIYHCSACKKDFNARKHYRSHMERIHKSEGERPRIHECDICKKTFKDKFVLNTHKKTHFNIKAHKCPMCEYACNNLTYMRQHVMNHTNQLQFKCHICYRGFMTDSELQVHVDKLHANEPQVYSCNVCGKISTSKGNLRQHQKIHNPDHNQKKDHQCAECGKTFALKCRLKKHVLSHKGQDKCHCSICGKLLSKDSYKKHLKAHSGERPFLCDYCGESFTTNSCLMGHRRTHTGEKPLKPYICDQCGKSFVQSSTMEAHRKTHANGTTKSYSCDECGRLFSQASQLTSHRKVHETLFCDICGKTFTDHSLLFSHTNMYHVPERPYNFIGFNSQSGLSDGKDAKIFGEWLGNSSKKKTNAVVLTGTRNSLRKRVRNPKYANYNNVYEVNHRRSSSSQGKKVVSSETEPRNSGDNFAGGRSDGTYPSNVSSSLPECNKKSPDSQDDTICHVCGKAEKSKKLLRRHMVKHSDERPFSCSQCPKRFKRSYEVKAHVKVMHETQQKDYKCEVCGHQYAIRSKLEIHMRRHRKEYKCTCLECGKGFYSDFKLKEHFYIHTGEKPYQCEVCGRSYAYKTDLIAHKVAQHPETCDPSRVHKCEKCGKTFSTAKALQTHENTHTGENLFPCTLCSKVCSTKKLLKSHLVRHTSLRPYPCDVCHKTFKRPFEVAIHKKSHETDKKHICELCGYSALRKTSLDLHIRRHKKEFKVTCETCGKGFYSDFKLREHVNIHTGAKPFQCDICGKGYPYKWNLTSHKRIAHPETCDADKTQKCDVCWKTFACKRTLKEHMKLHSEQSNSTCDICGKTFAKSSKLDLHRETHASEGLTTLVEPEQETDLIETMNIYYF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-