Basic Information

Gene Symbol
-
Assembly
GCA_018290095.1
Location
CM031382.1:13384017-13385018[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.0054 0.25 11.9 3.5 2 23 49 71 49 71 0.96
2 10 0.0003 0.014 15.8 2.3 1 23 80 103 80 103 0.97
3 10 0.11 4.9 7.8 0.5 7 23 117 134 111 134 0.89
4 10 3 1.4e+02 3.3 2.7 2 20 140 158 139 159 0.77
5 10 1.5e-05 0.00068 19.9 2.9 2 23 167 188 166 188 0.97
6 10 3.4e-06 0.00015 22.0 2.5 1 23 192 214 192 214 0.98
7 10 2.5e-06 0.00011 22.4 2.4 1 23 218 240 218 240 0.98
8 10 0.0011 0.048 14.1 8.4 1 23 248 270 248 270 0.98
9 10 0.00061 0.028 14.8 2.3 2 23 279 300 278 300 0.97
10 10 0.00028 0.013 15.9 0.7 2 23 308 330 307 330 0.96

Sequence Information

Coding Sequence
atgtcatcatcatcaagtaCAAATCAAGTGACATCAAGTGAAACCAAATCTGatttaaaaagtgattttctcttgttaataagtaatgaaaatcaaaatgataaaaaagcaaaatttgcagatcaaatgaataaaaatgtaaattccTGTAAAATttgcaagaaaaaattatattcaaaaaataaatttatgcagcatatgaaaaatcttcattcaaacgaaatttcatcaaaagtttatttttgtgatCATTGtcctaataaatttattcagaaaGTTTCATtgatttctcatttaaaatcaaaacatcaaaaaggaaaagaaatcaaatttgaatgcgattttgatggaaaaatttttggtacaaaaaagaaactttataaTCATATGACAACATGTCATCAAACCATCaaacaaaaatgcaaaatttgtaGTAAAAAggttaaatttttagattcaCATATGAAACATATTCATGCTAaggaagatgaaaaattgcaatgtcaaatttgtaataaaacatacaaaaatcaaacttatttaaatcaacattttaaatCACACAATAAACAGCATCAATGTCAAATTTGTGGACGAAAATTTGCAttgaaatatcaattaaaagaaCATCAAAAAGTTCACGATGGACAATTTAGAtgcaaaatttgtttcaaaaaattcactcaaataggaaatttaaaaactcatttgaaaattcatgacACAAATCGTCCAAAACCACACAAATGTCAACATTGTGAGTATTCAACTGATCAGAAACAACATTTGATAAAACATCTTAAGACTCATGacaaaaacagagaaaaaaacttaaaatgcAATCAATGTGATTATAAAACTGATGATAAAGGACATTTTAAGGAACATCTTCAAATTCACAATCCAAATCGTGTGAAAATTCCATGTTTGTACTGCAAATATGAAGCAACTCAAAGAAGCAATTTGAATACACACATCAAGCGTAAACATGATCCAAACTGA
Protein Sequence
MSSSSSTNQVTSSETKSDLKSDFLLLISNENQNDKKAKFADQMNKNVNSCKICKKKLYSKNKFMQHMKNLHSNEISSKVYFCDHCPNKFIQKVSLISHLKSKHQKGKEIKFECDFDGKIFGTKKKLYNHMTTCHQTIKQKCKICSKKVKFLDSHMKHIHAKEDEKLQCQICNKTYKNQTYLNQHFKSHNKQHQCQICGRKFALKYQLKEHQKVHDGQFRCKICFKKFTQIGNLKTHLKIHDTNRPKPHKCQHCEYSTDQKQHLIKHLKTHDKNREKNLKCNQCDYKTDDKGHFKEHLQIHNPNRVKIPCLYCKYEATQRSNLNTHIKRKHDPN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-