Pvan002084.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Polypedilum vanderplanki
Gene Symbol
ZEB1
Assembly
GCA_018290095.1
Location
CM031380.1:28796648-28801698[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.01 0.48 11.0 0.1 2 23 100 121 99 121 0.97
2 16 8e-05 0.0036 17.6 3.5 2 23 126 147 125 147 0.97
3 16 0.00019 0.0085 16.5 1.1 1 23 151 173 151 173 0.97
4 16 0.00017 0.0079 16.6 1.2 1 23 199 222 199 222 0.96
5 16 0.00042 0.019 15.4 1.7 1 23 229 251 229 251 0.98
6 16 4.1 1.9e+02 2.8 0.3 3 23 259 282 257 282 0.89
7 16 5.4e-05 0.0025 18.2 2.8 1 21 289 309 289 310 0.96
8 16 0.17 7.7 7.2 6.9 1 23 498 521 498 521 0.95
9 16 0.00088 0.04 14.4 1.3 1 23 533 556 533 556 0.95
10 16 0.0023 0.11 13.0 4.4 1 23 562 585 562 585 0.94
11 16 0.00016 0.0074 16.7 6.2 1 23 591 613 591 613 0.98
12 16 1.8 83 3.9 0.4 2 10 618 626 617 637 0.72
13 16 0.0011 0.05 14.1 1.3 1 23 646 668 646 668 0.96
14 16 0.00069 0.032 14.7 0.7 3 23 681 702 680 702 0.94
15 16 0.006 0.27 11.7 4.3 2 23 709 732 708 732 0.95
16 16 0.00024 0.011 16.1 0.7 2 23 739 761 738 761 0.95

Sequence Information

Coding Sequence
ATGGCAGTCAGTAGtgaaaataatataatatataatgaagatatgaataatttaaaagaatcatGTACTatgtgtaaaaaaaattcagctAGTTTAGCAGAAAatcaaaatggaaataaaatttgtaaagaatgtAGGGCAAGTAATCTaaaaacaagagaaagaaaatgtcgAAGATGTAAAAAATACACAACtgtaaatattaaagaaaataatgcaTTTACTAGAAAATGTGATGATTGctttaagaaaaagagaacaaaagGTCCTAAACCAAAACCTGTGATAAATTTTGTCCAATGTGATCTTTGTGGGGTGAGTTTCGATAAAAAGATTCTCATTTATGCTCACATGGATAAGCATAGATCAGATACAACTTGTCGTGTGTGTCATGCTTCATTCTCACGTAGAAACACTCTTCGTATACATCTTCGCACtcattttgaaaactttatttgTGAGCAATGTGGATATTCTACAACTAATAAGATCACATTCAGAAATCACATAAAACTTCATAGCGTAGTTAACGTCAAtgataacaaaattcaaaaacaacaaGTGAAATATAGATATCCTGTTGTTAGAGGAAGCTTCCCATGTTCTCATTGTGgcttaattttttcaacaaaaacaaCATTAATTGGACATGAGAAGAGGCAACATGAGAGTGGAAATAAAGGATTCAAGTGCCAGAATTGTGGTTTAACTGTTTTCAGACAGAAAGAATTTCGTGAACATTTGATGACGCATTCCAATAAGCCACTTCTTTTTTGTCAATATCCAAATtgtgattattattataatactGTTAAACGTATGAATATGCATATTCGAGCTGTTCATGAaactaaaaatgataattatgaatgtcaaaattgcaaaaaaaccTTCAAGCATAGAATGTCACTCGAAAAGCATCAAATGAATAATAGATGCATACCATTGAGTAtcagaaaattgaattcagcaaagaaaaatatttcaaaaagcacaaaatatgtggaaaataaaacaaaagaagagtTAGAAAGAAACGCAAAATTAGCTAAAGAACAGTATTTAGAAATCAGAGgactaaataaaattattgaaaaagagaaagaagaggaTACTGATAATGATGTGTTTAAGCAAGTAAATGATTATTTAGATCAAGacacaaaaattaatgatgaccTGGAGAATATAAATGTTCAACCatttgttaaaattgaaataaagtcTGAGCCAATCGATAATGAGATGGTTTTAATAGAAAACAcatataatgaagaaaaaatatcaaatgcattgaataaaattatgccAATACATAATCGTTTTCCTATCGTCTACCTTCAAAGACTAGATGAAAACATGCTTAAAagcatttcaattattaaaaaagaagaaaaagatgattCAGGTGTTGCTTTGATTCAATctgagaaaaaatcaaataataaaaaggatCGAAAAAAAGCTAGACAGAGGAATAAAGATCGAGttttttgttgcaaattttgtactgaattttttgttaaaaaaaaatcattaaaagatcatgaaaaatatttccataagACTGAAATAGACAAGAATTTAACTCAAATTTATACATGCGATATGTGTGGAAAACAGTTTAATAAGCATGTGGCTATAAAAGTCCACATAAAATTTGTGCATCTGTCAACATCTAACTTTTCATGTTCTCATTGtcaattgaaatataaaacaaaaaatttcctcaagAGACACATTGAGGAGTCTCATCTTGGATTAAAAAGATTTAGCTGTCAATTTTGTGggaaagaatttaaaagaaaggAGCATTTACATGATCATGAAAATCGTCATGCAAATCCAGTAACATGTCATATTTGTGGTAAACTAGTAAAAAGTTTAGAACaacatgtaaaaaatattcataaagaaaaaaaggaagcTGAAACTTTTCCTTGTTCATTTTGCGGCAAGTTTTTCAACAAATATGTTCTCAAGACGCATATAAACAATGTTCATAACAAATTACATTATGCTCACACTATTGATAGACCTTGTCTTAAATGTGAACAAAAATTCACAAGACTGGAAGATTTGAaaagacACGAATTGATGAATCATTTTGAAGgtgtaataaaatattgtcatTATCAAGGCTGTAATAAAATGTTCAAAAGTGTAAAGTTACTTAATATGCATATGCATGTTCATGAAAGATCAGAGGAAGATACATGTAACAACtgtggaaaaatatttcaaacaatATCGGGTTTAAAGAAACATGCCCTAAAAAAGCATAATGTTTTATTGTGA
Protein Sequence
MAVSSENNIIYNEDMNNLKESCTMCKKNSASLAENQNGNKICKECRASNLKTRERKCRRCKKYTTVNIKENNAFTRKCDDCFKKKRTKGPKPKPVINFVQCDLCGVSFDKKILIYAHMDKHRSDTTCRVCHASFSRRNTLRIHLRTHFENFICEQCGYSTTNKITFRNHIKLHSVVNVNDNKIQKQQVKYRYPVVRGSFPCSHCGLIFSTKTTLIGHEKRQHESGNKGFKCQNCGLTVFRQKEFREHLMTHSNKPLLFCQYPNCDYYYNTVKRMNMHIRAVHETKNDNYECQNCKKTFKHRMSLEKHQMNNRCIPLSIRKLNSAKKNISKSTKYVENKTKEELERNAKLAKEQYLEIRGLNKIIEKEKEEDTDNDVFKQVNDYLDQDTKINDDLENINVQPFVKIEIKSEPIDNEMVLIENTYNEEKISNALNKIMPIHNRFPIVYLQRLDENMLKSISIIKKEEKDDSGVALIQSEKKSNNKKDRKKARQRNKDRVFCCKFCTEFFVKKKSLKDHEKYFHKTEIDKNLTQIYTCDMCGKQFNKHVAIKVHIKFVHLSTSNFSCSHCQLKYKTKNFLKRHIEESHLGLKRFSCQFCGKEFKRKEHLHDHENRHANPVTCHICGKLVKSLEQHVKNIHKEKKEAETFPCSFCGKFFNKYVLKTHINNVHNKLHYAHTIDRPCLKCEQKFTRLEDLKRHELMNHFEGVIKYCHYQGCNKMFKSVKLLNMHMHVHERSEEDTCNNCGKIFQTISGLKKHALKKHNVLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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