Basic Information

Gene Symbol
-
Assembly
GCA_014622435.1
Location
JACWBX010002191.1:1374-4865[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 1.1 50 4.6 2.8 1 22 82 105 82 108 0.92
2 15 0.26 12 6.5 1.8 5 23 122 141 120 141 0.94
3 15 0.33 15 6.2 3.2 1 23 145 168 145 168 0.97
4 15 0.013 0.6 10.6 0.1 1 20 191 210 191 215 0.93
5 15 8.3 3.9e+02 1.8 0.1 1 22 605 625 605 628 0.77
6 15 0.00018 0.0081 16.5 2.6 2 23 669 690 668 690 0.97
7 15 0.054 2.5 8.7 0.8 2 23 698 720 697 720 0.96
8 15 0.054 2.5 8.7 4.4 1 19 727 745 727 747 0.97
9 15 0.087 4 8.0 4.2 1 19 774 792 774 797 0.92
10 15 0.004 0.18 12.3 0.1 3 23 819 840 817 840 0.93
11 15 7.1 3.3e+02 2.0 0.1 2 10 880 888 879 903 0.79
12 15 0.025 1.1 9.8 0.4 2 23 908 929 907 929 0.97
13 15 4.5e-06 0.00021 21.5 1.1 1 23 937 960 937 960 0.97
14 15 0.25 12 6.6 4.5 1 23 969 992 969 992 0.95
15 15 0.09 4.2 8.0 2.2 2 23 1002 1025 1001 1025 0.91

Sequence Information

Coding Sequence
ATGAAAAAGATAAATAAATCAATAATTCCTAAGTTTCACGAGATCAAACTTGAACATGATCCAATTGAAGTAAAAGAAGAAAATGAGAAAAATGTTGTTGAAATTGTTTTACAAGATCCTTTGGAAAAATTAGAAATTGATGTAAAAGAAGAATCGAAAAATACAGAAGAGCCAGAAAGTTTATCAGAAATTCAACAAACAGCAGAAACTGAAATTTCGTCAAAAGCTTCAACATTAAAAACTTTCAAATGTTCTCATGAAGGCTGCAATTTAGAATTTTTTACTAAAATCGAAAGATTTCACCATATGAAGCTTGCTGGACATCTTAATGAAATTGAAATTTCAAATCGTCAATATCACTGCTATTGTGGATTAATTTTTACCTCAAAACGTGAACAACTGAATCACATTCGATTGACTCATAATGCAAGATTCAAATGCAATTCATGCGGTCGAGTTGTATTTGATGAAAAAACTTGTCAAAGTCATATAAGAAAAACTCATGGTAGTGGATTTTTCACTGTTGGATTATTGACAAAAGGAATTAATGAAAACAATGGAAAAGAAGTTTTTAAATGTTCAATATGTGATTTAGATTTTGAAGATTTTCCAAATTATAAAATTCATTTGGATGGAATTGAACATTATGAAAATGGAACTCATTATTATGATGGTGGAAATGATGAAAGTAGACAAGATTTTAAACTTATTGAAGAAATTGGAAAGAAAAATAGGATGAAAGGTTTACAAAATCAACAACTGATGAAAAACCTAAATAATCAACAAAACAATTCAATTAGTTTACAATTTCATCAAGGATTGAAGCAAAACGATGAAATTTTACATGAAGTTGACATGCAAATTAAAGATAAAAAAAAATCTCTAAATTTAGAAAAGAATCAAAAATGTTTACAGAAAATTGCTATAACAACTGAAAATATTGATGATGTTAGTTCAAATTTATTTGAAAATGCAGAAAGTTCTTCAATAACAACAAAATGTTTGAAAAATTCAACAAAAATTAAAAATATTTCATCTAAATTTAAACAAACTTCAAAAGATCAAAATTTAAATAAAAATCCAGCAAAAATAAACTCTAAATTGTCAAGTGATGCTCCTGAAGACTCCGAATCTTATCTTAATAATTTAACTAACGAATATTTCAATAAATTTATCAATCCAAATTTTACAAATTCATCAATTGTTTCACCATCTTCAAATGTTAATCAGCATTCCTCAAAACAGTTTGGAAATTCACACACTTCGGTCAAAGTTGAAGAAAATTTAAATTTTTCAATCAAAGTTTTATCAGATTCATTAGAAACTTCTTCATTTTTTGATCCTTTAAAAATTGAGAAACCTGAAGAAATAACAATTATTCAAGAATTCAATCAAAAGAAATTAAACTTTATCACAAATGATGAGAAATTGATAAATTTTCATCCAGTGGTTGAACTAGAAAGAATAAAAATTGAAGAAAAGCGAATTAATTTAAAAGAATTTTTTGAATCAAAAAAACAAGTCAACATAATGTTCGATTCAAATTGTATAAAAGTTGAAGATGATCGAAGTCAATTAGTGATAATGAATGAAAATGTTGCAAGCAATGAAACAAATCAGCAAAATTCAACAATAATTGATCAAAATGTCACTTGTGAGACATGCAATAAAACAATGGCTTCATCTTTTTACCACAATTATCATCTCAATGCACCATTCCATAAATTTTTCCTTGAATTTCCACAATTTCGTCCACAAAAAACTAAAAGACAGCAAAAACTTTCTGAAAGAATTCAACTACAGAAGATGAAATTTCCATGTGATGTTTGCCAAAAAGGAATTGTTGCAGCTTATTATAAAATTCATTTAAAATCATCATCACATAAATTTTATCTTAGTAATTCTGATGCTGAAAGAAAAAAACGAAAACCAAGATCTAGAAATGAAGATTTTAGCAAAGATATTTTAATTGAAGAATATGATTCAAAGAAATCTTTAGCTTTGGTATGTGATTATTGTAGGAAAAAATTCTTCAAGAAATATCAATTGGAAAATCATGTGAAAAGACATTGTAGCAGCTTTTATGTTGTTCCTTGCACATTTTGTAATGAAAAATTTTTAAACCAATCAGCAATGAATATTCATAGAAAGAAAAATCATGCGAGCAATGATGGAAGCTATCATTGTGAAATTTGTAATAAAAGTTATGAAAGACATCGAGAATTTTTGAGACATTGTGCTAGTGTTGGTCATTTGAAAATTTTAAATGGTGGAAAAGCTTTAAAAGAGGAAAAACGATCATCACATATCAAAGAAAATTACACTTGTTTTATTTGTAATCAAAATTTTTCAAATGGCGATTCATATAAACGCCATTGTGGCACTTATCATGTAGATGGAAATGAATTTTGTACTCGTCGTTATAAAACAACAACACCATTTACTGATGTCAACTGCAAATTATGTTTTGAGAGTTTTGAAACACCGAATGACTTGCAAATTCACTACGTTATGGATCATGATAATTCAGAGTCTTTCAAGCACATGGGAAAAGCACTACTTACATGCCATTGTGGAAAAATGTTATCAAGAAATCTTTTTAAAATTCATGTTGATAAATTTCATCCAGCATCGACTGTTTGTGAAATTTGTGGCATAAATTTTGGTGAGAATAGAGCAGGCTTCAGGTATCATCGTCAATATGGTCACTTGCCTTTCTTAACTTGTGATATTTGTGGCTATGAAGTTCAATCAATGACAAGATTAAAAACGCATATTAAACGACACTTAAACATCATAAATCATTGTTTTGTCTGTGAAATTTGTGGAAAAAGTTATGGCAATCAAAATCATTTAGATCGGCATATTCAGAAAAATCATGAAGGTGAAAAAATTCCAAAAATTTATGAATGTGATCAATGTGAGAAAAAATACAAATGTCCGAAATCATTGAAGGAACACAAAATGTATAAGCATCAATCAGCAGAAAGAATTTTTAAACTTTCATGTGAAATTTGTGGATTAAAATTTGAAAAACTGTGCAAATATAAAAATCATGCAAAAACAGCAAAACACATTGAAAAAGCAAACGCTTTGGGAGTTCCAATTTATGATCCTAAAAATTTTTAA
Protein Sequence
MKKINKSIIPKFHEIKLEHDPIEVKEENEKNVVEIVLQDPLEKLEIDVKEESKNTEEPESLSEIQQTAETEISSKASTLKTFKCSHEGCNLEFFTKIERFHHMKLAGHLNEIEISNRQYHCYCGLIFTSKREQLNHIRLTHNARFKCNSCGRVVFDEKTCQSHIRKTHGSGFFTVGLLTKGINENNGKEVFKCSICDLDFEDFPNYKIHLDGIEHYENGTHYYDGGNDESRQDFKLIEEIGKKNRMKGLQNQQLMKNLNNQQNNSISLQFHQGLKQNDEILHEVDMQIKDKKKSLNLEKNQKCLQKIAITTENIDDVSSNLFENAESSSITTKCLKNSTKIKNISSKFKQTSKDQNLNKNPAKINSKLSSDAPEDSESYLNNLTNEYFNKFINPNFTNSSIVSPSSNVNQHSSKQFGNSHTSVKVEENLNFSIKVLSDSLETSSFFDPLKIEKPEEITIIQEFNQKKLNFITNDEKLINFHPVVELERIKIEEKRINLKEFFESKKQVNIMFDSNCIKVEDDRSQLVIMNENVASNETNQQNSTIIDQNVTCETCNKTMASSFYHNYHLNAPFHKFFLEFPQFRPQKTKRQQKLSERIQLQKMKFPCDVCQKGIVAAYYKIHLKSSSHKFYLSNSDAERKKRKPRSRNEDFSKDILIEEYDSKKSLALVCDYCRKKFFKKYQLENHVKRHCSSFYVVPCTFCNEKFLNQSAMNIHRKKNHASNDGSYHCEICNKSYERHREFLRHCASVGHLKILNGGKALKEEKRSSHIKENYTCFICNQNFSNGDSYKRHCGTYHVDGNEFCTRRYKTTTPFTDVNCKLCFESFETPNDLQIHYVMDHDNSESFKHMGKALLTCHCGKMLSRNLFKIHVDKFHPASTVCEICGINFGENRAGFRYHRQYGHLPFLTCDICGYEVQSMTRLKTHIKRHLNIINHCFVCEICGKSYGNQNHLDRHIQKNHEGEKIPKIYECDQCEKKYKCPKSLKEHKMYKHQSAERIFKLSCEICGLKFEKLCKYKNHAKTAKHIEKANALGVPIYDPKNF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-