Basic Information

Insect: Polypedilum pembai
Gene Symbol: zfh1
Assembly: GCA_014622435.1
Location: JACWBX010000130.1:10969-24726[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.004 0.18 12.3 0.1 3 23 26 47 24 47 0.95

2 9 1.1 51 4.6 2.5 2 23 103 127 92 127 0.93

3 9 0.0015 0.069 13.6 4.4 3 23 136 156 134 156 0.95

4 9 3.8e-06 0.00018 21.8 6.1 1 23 165 187 165 187 0.99

5 9 0.00012 0.0055 17.0 1.6 1 21 193 213 193 214 0.95

6 9 0.046 2.1 8.9 0.5 2 15 429 442 428 448 0.85

7 9 7.4e-06 0.00034 20.8 0.8 1 23 732 754 732 754 0.95

8 9 0.00014 0.0063 16.9 7.2 1 23 760 782 760 782 0.98

9 9 0.0028 0.13 12.8 4.3 1 21 788 808 788 809 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.004	0.18	12.3	0.1	3	23	26	47	24	47	0.95
2	9	1.1	51	4.6	2.5	2	23	103	127	92	127	0.93
3	9	0.0015	0.069	13.6	4.4	3	23	136	156	134	156	0.95
4	9	3.8e-06	0.00018	21.8	6.1	1	23	165	187	165	187	0.99
5	9	0.00012	0.0055	17.0	1.6	1	21	193	213	193	214	0.95
6	9	0.046	2.1	8.9	0.5	2	15	429	442	428	448	0.85
7	9	7.4e-06	0.00034	20.8	0.8	1	23	732	754	732	754	0.95
8	9	0.00014	0.0063	16.9	7.2	1	23	760	782	760	782	0.98
9	9	0.0028	0.13	12.8	4.3	1	21	788	808	788	809	0.96

Sequence Information

Coding Sequence: ATGGCAACGGGAATGATTTCAACTAGAAATGAAGATGAATCATTGCAACAAGCAAATAGTGCTGAATTTATGAATTGTCCTCAATGTCAACTTGAATTTAATAGTCCACAAGCATTTAAAGAGCATATAATGCAAGTACATCAATTAGTTCCGCCAAGTATAATGCAACAACAATTAGCATCAACGTCATCGCACTTTTCATCACCACCACCGTCAATGATTTCACCTGGCAACAATAATAACAATTATTTTACAGGTGATGAAGGTGGGCGTTCATCGCATAGTCCAAGTCATACAAATACTCACGCATGCTCTCACAGTCAATGCTCCGCCTCATTTCCCACGATTGAGCTGCTTGAAAAGCACGAACTTATCAATCATTCATCAGGTGCAACGAATGTGTGCTGTCGATTGTGTCACAAAACATTCGCAAATGTTTATCGTCTGCAACGGCACATGATTTCACACGATGAATCAGCTTTGTTGAGAAAGTTTAAATGTTCTGAATGCGATAAGGCTTTTAAATTTAAACATCATTTAAAGGAACATTTACGCATTCATTCAGGCGAAAAACCATTCCAGTGCCTAAATTGCGGCAAGAGATTCAGTCATTCCGGCTCTTATTCCAGTCATATGACGTCAAAGAAATGTATTAGCATGGGCTTGAAAATGAACGGCGGTTTGAATGGTGGTGGCACGAGTACAGTAATGAATGGCAGTGGCAATGCGTCTCATATGAACGGTCATAATAAAATGAAATTAGAGAAGAAACAACAAGGGACAACACAACCATCATTGGGACAAAATTTCATGAGTCAATCGCTTGAAAGCTTCATAAAAGGCGGTGTGCTGCCGAATTCCAATTTATTTCTTCCAATGGTTCCAAATCTGCATGAAAATTATGGCGTTATGAATGCAGCATTTTTAGCTTCACTCTCAAATCCACTTTATCCAATAAATTTAAATCCATACCACATTCAAAATTTATTTAAACTCAGTGGCGTGCCGCACTTAAATCCAGCATCAATGGATGATGAATCACAATCGAAATCATTGGATGAGCCAAAAAGTCCAGCTGAAAATGATCGTCATTCAAATCCTGAAGATTTAATTGAAGAAGTGAACGAGCATGAAGATTCAAAGCTTGTTATGGACATTGATGATCGACAACAGCATAGTGAGAAGCATGAAAGTGATGATGATGAAAGGTCAATGAATGAAATGTCACCGAGAAATGATAAATCACCTTCACCAGCAAGTTCTATAAAGCAAGAAGATTCATTACGTTGTCGACATTGTGATAAAGTTTTTAATCATCCAGCTGAACATTTACAACATGAGACAGTTCTTTGTAGCTCATTGATGATGAAAAAACATGAAAATTTGATGATGCATATGGCTGACAATCTTTCAATGAGTATAAATGAAGAAGACATGGATGATCGTGAATCAAAAGTTTCAACAGAATCAGAACGTAAAGTTCGTGTAAGAACTGCAATTTCAGAAGAACAGCAAGCAATTTTGAAAGAATTTTATTCCATCAATCCTCGTCCAAATCGTGAAGATTTTCGTAACATTGCTCAACGACTTATGCTTGATGCTCGTGTCGTACAAGTTTGGTTTCAAAATAATCGATCGAGAGAGCGAAAACAAAATGGCTCTGGCATGAATTTCAAACAAGAAAGTGGTGAAGATCAACCACTTGATTTGTCAATGAAAAAAGATTCTGATACACCAACAAATTCACCTCGTTATGGTTTAGTTCCAAATGATGCTGGAGCAATTAATTTAAGTCGCAAAATGGCTTCATTTTCGCCTTTATTTCAACCAAATTTTAGTGCTGATTTTCTTTCAAGACAAATTCCATCACCAAATGAAGCTGTTTCACATTTACCAACTGCTGCTGCTGCTGCTCGTAATGGAATGGGTTATAATTTGCCTTTGGGATTGCCATTAGAACGTTTATTACAATTCACACCTGAAATGGCTCGAAATCCTTTGCTTATGATGAAAAATGATTTGCGAAGTCCAGCAAATAGTCTCAGTCCAGGCAGCTCTGAGAAACGTTCATGGAAAGATGACGAAAGTCGCTCATTAGATGAAAGTTTACATCACCATCAGCAGCCTTATCAACCACAACGACGTATGCCAAAAATGAAATCTGAAATTCCACCTGATTCAAGTGAATTTCAATACGTTTGTGACCTTTGCGATAAGGCATTCAGGAAACAAAGTTCATTGGCGCGTCATAAATACGAACATTCCGGTCAACGCCCATTTAAATGTGTTGAATGTCCGAAAGCATTTAAGCATCGTCATCATTTGACGGAGCATAAGCGCCTGCATTCGGGTGAAAAGCCGTTCCAGTGTTCAAAGTGCTTAAAGCGATTTTCTCATAGTGGCTCATATAGTCAGCATATGAATCATAGATACAGCTACTGCAAGCCATATAGAGATTAG
Protein Sequence: MATGMISTRNEDESLQQANSAEFMNCPQCQLEFNSPQAFKEHIMQVHQLVPPSIMQQQLASTSSHFSSPPPSMISPGNNNNNYFTGDEGGRSSHSPSHTNTHACSHSQCSASFPTIELLEKHELINHSSGATNVCCRLCHKTFANVYRLQRHMISHDESALLRKFKCSECDKAFKFKHHLKEHLRIHSGEKPFQCLNCGKRFSHSGSYSSHMTSKKCISMGLKMNGGLNGGGTSTVMNGSGNASHMNGHNKMKLEKKQQGTTQPSLGQNFMSQSLESFIKGGVLPNSNLFLPMVPNLHENYGVMNAAFLASLSNPLYPINLNPYHIQNLFKLSGVPHLNPASMDDESQSKSLDEPKSPAENDRHSNPEDLIEEVNEHEDSKLVMDIDDRQQHSEKHESDDDERSMNEMSPRNDKSPSPASSIKQEDSLRCRHCDKVFNHPAEHLQHETVLCSSLMMKKHENLMMHMADNLSMSINEEDMDDRESKVSTESERKVRVRTAISEEQQAILKEFYSINPRPNREDFRNIAQRLMLDARVVQVWFQNNRSRERKQNGSGMNFKQESGEDQPLDLSMKKDSDTPTNSPRYGLVPNDAGAINLSRKMASFSPLFQPNFSADFLSRQIPSPNEAVSHLPTAAAAARNGMGYNLPLGLPLERLLQFTPEMARNPLLMMKNDLRSPANSLSPGSSEKRSWKDDESRSLDESLHHHQQPYQPQRRMPKMKSEIPPDSSEFQYVCDLCDKAFRKQSSLARHKYEHSGQRPFKCVECPKAFKHRHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01249981;
90% Identity: iTF_01248996; iTF_01249981; iTF_01250498;
80% Identity: iTF_01248996;