Ppem006463.1
Basic Information
- Insect
- Polypedilum pembai
- Gene Symbol
- -
- Assembly
- GCA_014622435.1
- Location
- JACWBX010002158.1:15261-18034[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 1.4 67 4.2 0.5 2 11 17 26 16 30 0.89 2 11 0.001 0.047 14.1 3.3 1 23 191 214 191 214 0.94 3 11 4.7e-06 0.00022 21.5 1.1 2 23 222 245 221 245 0.95 4 11 0.00023 0.011 16.1 0.5 2 23 251 273 250 273 0.96 5 11 0.75 35 5.1 2.6 1 23 279 301 279 301 0.95 6 11 0.0035 0.16 12.4 1.2 1 23 310 333 310 333 0.97 7 11 0.00018 0.0084 16.5 1.5 5 23 343 362 341 362 0.96 8 11 3.4e-05 0.0016 18.8 2.3 1 23 368 393 368 393 0.96 9 11 2e-05 0.00091 19.5 0.7 2 23 400 421 399 421 0.96 10 11 5.8e-05 0.0027 18.0 0.2 1 23 426 450 426 450 0.96 11 11 0.0013 0.061 13.8 9.4 1 23 456 478 456 478 0.95
Sequence Information
- Coding Sequence
- ATGGAAGGAATAAAAGTCAATGAAATAAATTTTGATAATCATATCAATAAATGTCGAATTTGTTTTAAATCCTTCAGCATTGAGGAGCATCAAATTGAAATTACTAAAGCAATTGAAAAGAAGTTCAATGAGATAACACAAATCAATTTAAAACTTACGAAAGAAACATCAAAAATAATTTGTGTGATTTGCAGTTATCAATTATCAACAATTTCACAAGCCAAAAAGAATATGATTTTAGCTCAAAGAGCGCTTCAAAATTATTTGAAAAAATTAAAGCCAAAAGCTAGTTCAACTAAATCACAAGAATTGAATTTTCTTGAACTTAAAAATAATGAAATGTTTTTGAAAGATGATGAAGAAGTAATTGAAGAACATTTGATTGATGATGAACAATTTGTTAGTGGAATTGCTGAAGAAATTATCATCAAAGAAGAAGAAATTAGTAAAAATGAAGAAGAACAATTCTGTGATTTTGTAGAAGAAAAAAGTTTAAATTTAAAAAGTTCACAAGTTAGCAATATAAGTTTCGAAACTTCCATTGAAAACGACCAAAAAAATCATAAAAAATTCACATGCCATGACTGTGGAAAGACATTTTCCTGTGGAGGAAGTCTTTCAAATCATATTTCAATTTTTCACTCAGTTGCAGCATTTGAACTTCCTTGCTCAGTGATTGATTGTGAAAAGAAATTCAAAACTAAAAAACAATTGACGCAACATTTAAAAACCCACAATGAAGAAAAGCAAGTTTGTCCTGAATGTGGATTGCTAGTTGGCAATAAACACAATTTGACTAAACATATTAAAAGATTACATTTGAAAATATACAGCTTCTTCTGTGATTTGTGTGATTATAAAGGATTTTTTAAATTTAATATTGACCAACATATGAAAAAACATTTAGACAAAAGCGAACGTGAAAGATTTTACTGTGATGAATGTAATTTTGAATCAATATCGAAAATGTCATTGAGAACTCATAAAAGAATGGAACATTTGGGGCAGAAAAAAACTTACATTTGCCATTGTGGAAAAACTTTTACTCAAAGCAGTTCCTACTACACTCATGTTCGAGTTGTGCATCAGAAAATTAAAAATCATTCTTGCACTTATGCTGATTGCAATAAAAATTTTGCTGAAAAATCTCAATTAAAAAATCATATCAAATCTCAACATTTAAAAACACGTGATATTCCATGTCCACAATGTGAAAAATTATTCGCAACTCAGAAGCATTTGACAGCTCATTTAAAGTATCATCGACCGCCATCTTATATTTGTGAATATGGAAATTGTGGAAATGCTTTTTACACATCAAGTCAATTAACAGCTCACTATAAAGTACACAATAATCAAAGAGATCATGCATGTCATTTGTGTGATAAAAGATATTTCCATAGATCTCATTTAAAGAAACATTTGATGGCACATTCGAGTGGTGTTTTTCTTTTGAGATAA
- Protein Sequence
- MEGIKVNEINFDNHINKCRICFKSFSIEEHQIEITKAIEKKFNEITQINLKLTKETSKIICVICSYQLSTISQAKKNMILAQRALQNYLKKLKPKASSTKSQELNFLELKNNEMFLKDDEEVIEEHLIDDEQFVSGIAEEIIIKEEEISKNEEEQFCDFVEEKSLNLKSSQVSNISFETSIENDQKNHKKFTCHDCGKTFSCGGSLSNHISIFHSVAAFELPCSVIDCEKKFKTKKQLTQHLKTHNEEKQVCPECGLLVGNKHNLTKHIKRLHLKIYSFFCDLCDYKGFFKFNIDQHMKKHLDKSERERFYCDECNFESISKMSLRTHKRMEHLGQKKTYICHCGKTFTQSSSYYTHVRVVHQKIKNHSCTYADCNKNFAEKSQLKNHIKSQHLKTRDIPCPQCEKLFATQKHLTAHLKYHRPPSYICEYGNCGNAFYTSSQLTAHYKVHNNQRDHACHLCDKRYFHRSHLKKHLMAHSSGVFLLR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01250443;
- 90% Identity
- -
- 80% Identity
- -