Basic Information

Insect: Polylopha cassiicola
Gene Symbol: ZFX_1
Assembly: GCA_038024825.1
Location: CP149061.1:295594-301572[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.043 2.4 9.2 3.1 1 23 272 294 272 294 0.98

2 25 1.3 75 4.5 0.1 3 23 334 355 333 355 0.92

3 25 7.1e-06 0.00041 21.0 0.5 3 23 382 402 381 402 0.98

4 25 0.12 6.6 7.8 0.1 1 23 411 434 411 434 0.93

5 25 0.013 0.71 10.8 0.2 3 23 442 462 441 462 0.97

6 25 7.7e-05 0.0044 17.8 0.2 1 23 468 490 468 490 0.95

7 25 6.5e-05 0.0037 18.0 1.0 1 20 496 515 496 517 0.95

8 25 0.25 14 6.8 1.8 1 23 590 612 590 612 0.96

9 25 0.00093 0.053 14.4 2.2 2 23 619 641 618 641 0.92

10 25 8.7e-06 0.00049 20.8 3.7 1 23 647 669 647 669 0.96

11 25 8.5e-06 0.00048 20.8 0.9 1 23 675 697 675 697 0.98

12 25 0.00092 0.052 14.4 0.2 1 23 703 725 703 725 0.97

13 25 0.00051 0.029 15.2 0.3 1 23 749 772 749 772 0.97

14 25 9.5 5.4e+02 1.8 0.0 2 23 810 830 810 830 0.85

15 25 0.0011 0.065 14.1 0.0 1 23 836 859 836 859 0.95

16 25 0.00037 0.021 15.6 1.0 1 23 865 887 865 887 0.95

17 25 0.0017 0.098 13.5 0.0 1 23 893 915 893 915 0.98

18 25 0.0042 0.24 12.3 0.0 3 20 927 944 926 946 0.93

19 25 3.6 2.1e+02 3.1 1.8 1 23 994 1015 994 1015 0.91

20 25 0.0059 0.34 11.9 0.5 3 23 1198 1219 1197 1219 0.95

21 25 0.055 3.1 8.8 0.0 1 23 1227 1249 1227 1249 0.94

22 25 0.00019 0.011 16.6 0.4 2 23 1256 1277 1255 1277 0.96

23 25 0.044 2.5 9.1 0.2 2 23 1284 1305 1283 1305 0.95

24 25 0.0023 0.13 13.1 2.4 1 23 1311 1333 1311 1333 0.96

25 25 0.00045 0.026 15.4 0.1 3 23 1342 1363 1340 1363 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.043	2.4	9.2	3.1	1	23	272	294	272	294	0.98
2	25	1.3	75	4.5	0.1	3	23	334	355	333	355	0.92
3	25	7.1e-06	0.00041	21.0	0.5	3	23	382	402	381	402	0.98
4	25	0.12	6.6	7.8	0.1	1	23	411	434	411	434	0.93
5	25	0.013	0.71	10.8	0.2	3	23	442	462	441	462	0.97
6	25	7.7e-05	0.0044	17.8	0.2	1	23	468	490	468	490	0.95
7	25	6.5e-05	0.0037	18.0	1.0	1	20	496	515	496	517	0.95
8	25	0.25	14	6.8	1.8	1	23	590	612	590	612	0.96
9	25	0.00093	0.053	14.4	2.2	2	23	619	641	618	641	0.92
10	25	8.7e-06	0.00049	20.8	3.7	1	23	647	669	647	669	0.96
11	25	8.5e-06	0.00048	20.8	0.9	1	23	675	697	675	697	0.98
12	25	0.00092	0.052	14.4	0.2	1	23	703	725	703	725	0.97
13	25	0.00051	0.029	15.2	0.3	1	23	749	772	749	772	0.97
14	25	9.5	5.4e+02	1.8	0.0	2	23	810	830	810	830	0.85
15	25	0.0011	0.065	14.1	0.0	1	23	836	859	836	859	0.95
16	25	0.00037	0.021	15.6	1.0	1	23	865	887	865	887	0.95
17	25	0.0017	0.098	13.5	0.0	1	23	893	915	893	915	0.98
18	25	0.0042	0.24	12.3	0.0	3	20	927	944	926	946	0.93
19	25	3.6	2.1e+02	3.1	1.8	1	23	994	1015	994	1015	0.91
20	25	0.0059	0.34	11.9	0.5	3	23	1198	1219	1197	1219	0.95
21	25	0.055	3.1	8.8	0.0	1	23	1227	1249	1227	1249	0.94
22	25	0.00019	0.011	16.6	0.4	2	23	1256	1277	1255	1277	0.96
23	25	0.044	2.5	9.1	0.2	2	23	1284	1305	1283	1305	0.95
24	25	0.0023	0.13	13.1	2.4	1	23	1311	1333	1311	1333	0.96
25	25	0.00045	0.026	15.4	0.1	3	23	1342	1363	1340	1363	0.95

Sequence Information

Coding Sequence: atgggTAATGAGACTGAGCAAATATTTCTGTTGAATCCCGCTGGCGCTCAGTCGGGCTCAGGGCTTCTGCTGAAAGCCGGCGAAGCGCAATCTAGTGCAACTGTCAATCTTGAAAATGTGACTGACTTCTCCAACGTATGCCGCACTTGCGCCACCATCACCGAATTCGTCATCCCCATTTTTGAGGGCGAAGGTCTACAAAATAATCTGGCTGATAAGATACACAAGCACTTACCAatacagGTATCTCCACATGATTCCCTGCCCGTGGTGGTGTGCGTGCAGTGTGCGAGCACGCTGCTGGCGTGGCACGAGATGGTGGCGTGCTGCGAGCAAGCCGACGCCGCCCTCCGCACGCGCCACCACGTGCTGCACCGCACACACGCGCACGTACAGCCATCCACCAACCACAGGAAAGAAGCGGGAGCTCCAGCGGAGGAAGTAGAAAATAGGTCACAGACCTCggtacaattttatacgaTAGTAAAAAACGCGCTATCCGATCACTTGCACACGCTCAACGTCGACGAAGACGATCTCGATATCGAACTCGTCTGCCAGAAGTGTCCGCACCggcccgccgccgcctccgcccgCGCCCTCGCCGCGCACCTCGCCGCCGCGCACCGCCtcccgccgcgcgccgccgccgtcgCGCGCTTCCTCACGCGGCACCTCACCTTCGAGGAGACTCTCCGCGACACCGACTCCGACTCCGAACCCGCCCCACCCGCCGCACCCGCCCCACCGGCCCCACCGGCCCCACCGGCCCCactcgccgcgccgcccgccgagCCCCCGCCGCTGCCGCACCACCGCTGCCCCCTCTGCGAGAGCGTCTTCTCCTCCGGGACCCGTCTACGACACCATCTCAACTCGCACGCGGACCGGTCCGTCGCCTGCTGCGGCGCGCTCCACGCCGACCGCGCCGCGCTGCTGCGCCACCTGCGCGCCGACCACGCCCACCGCCCCGCGCACCCGCCGCCCGCCGGCGCCCTCTGTCGCTCCTGCGGACACCGAGCCGACGACGCGGCCAGCCTGCGCGCCCACATCGCCGAGGCGCATCGCGAGGACGCGGAGGCTCGCGCCCCCCCGGCCTCCGCGGCCCGTCGCTCCGCCGACCAGAAATACGTCCCGGCCGACTGCCCCGACTGCGGCGCGACCTTCTCGAACAAGTACAACATGTCGGTGCATCGACGGCGACACGCGTCGgacgcgccgccgccgcgccacGCGTGCGACTCGTGCGGCCGCACGTACGgcagccgcgccgccgccgcccgccacGCGCGCCTCGCGCACGCCGGCGCGCTGCCGGCGCTGTGCCCGCACTGCGGCGAGGCGTTCCCGACGCGCGGCGAACGCGACACGCACGCGCGGCTGCACACGGGCGCGCGCCCGCACGTGTGCCCGTACTGCGACAAGGCGTACCGCGCCGCCGACACGCTGCGCCGCCACCTCGACGCGCACCTCGACGTGCGCCGCCACCGCTGCCCGCGCTGCCCGAAGACCTTCCGCAAGAGCTCGCACCTCCGCGGCCACCTCGCCGCCGCCTGCGGACGCGACCGCCCCGCCCGCCCCGCCCGCCGCCGCCACTACCCGGACTTCACCGACTCGAGCGACGACTCGGAGccggcgggggcggcggcggccgagGCGGACGGGTTCGACGACCTCACCGGGCGCAACATGCGCGGCGACCGGCTGGACGAGAGCACGCGCCGCGAGCTCGGCGAGGCGCGCACGCGGATCGGAGGCCGCGCGTACTACTCGTGCCGCGAGTGCGGCAAGACGCTCGGCTCCGCGCACACGTTCGTGTTCCACCGGCGGATCCACACGGGCGAGCGGCCGTGCGTGTGCCACGTCTGCGGCAAGCAGTTCCGCGCGCCCAACGGCCTGCGCCGCCACCTCACCGAGACGCACGAGCGCGCACGCCGGCACGCCTGCCGCCACTGCCCCAAGAGCTTCGCCAACTCGCAGAACCTCAAGCAGCACCTGCGCATCCACACCGGCGAGCGGCCCTACGTGTGCGCGCTCTGCGGGAAGCGCTTCACGCAGAGCGGCTCGCTGCACGTGCACGCCAAGACGCACAGCGCGCTGCAGCCGCACCGCTGCGCCGACTGCGGCGCCGCCTTCCGCCTGCGCGCCGGCCTCGCGCGCCACCGCCTGCGCCACGCCGCCGGCGCGCCGCCCCCCACCGCGCTCCCCTCCGCCGCGCtccccgcccgcgccgcgccgcgcccgcACGTCTGCTCGCTCTGCGGCGCCGCCTTCGCCCAGCGCCGCGCGCTCCGCCTGCACGCGCGCCGCCTCcaccccgcgccgcccgccccgccCGACCCGCCCCTCTACCCCTCCGCCGCGCTCGGGGCGGCGCTCGCGCGACCCGTCGCCGTCACCGTCGACGGGgccgggcggcggcgcgccgAGTGCGGCGTGTGCGGCCGCCGCGTGGCGCCCGCGGGCTGGCGGCGGCACGCGCGCGCGCACCTGCCCGACCGGCCGCACCGCTGCGACGCCTGCGGGCTCGGCTTCGCGGACGCCGGCAACCTGGCGCGCCacgcccgcgccgcgcacGCCCGCGCGCGCCCGCACGCCTGCCGCCTCTGCGGCGCCGCCTTCTCGCGCCGCGCGCACCTGCAGGACCACGAGCGCGCGCACGGCTCCGCGCGCGAGTTCGTCTGCGACGAGTGCGGCGCCGCGTCCAAGTCGGCGGCGGCGCTGCGCATGCACCGGCGCGCGCACCGCGCCCCCGGCCCGCCCGCCGGCGCGCCGCCGTGCGTGCAGTGCGGCGCGCGCTTCCGCCGCGCCGGCGAGCTGCGCGCGCACCTGTCGGAGGAGGCGGCGGAGCCCCCGCCCCGGGAGCCGGCGGACCCGGAGCCGgcgagcggcgcggcgcggcgctgcgAGTTCTGCGCCGCGGAGCCGCCGGTCGCGCTCTACGCGGACCACCTGGTGGACGAGCACGCGCACCTCGTGTTCCACTGCGACGAGTGCGACCAGTACGTGCCGCGCCGCGAGCTCTTCCTCCACATGACGCGACACGCCGACCAGTACGTCGCCGCCGCCGAGCGACCGgccgcccccgcccccgcccccgcgCGACCGGCCGCCCTCGCCCCCCCCGAGCGACCGGCCGCCCTCGCCCCCGCCCCCGCGCGACCGGCCGCCCTCGCCCCCCCCGAGCGACCGGCCGCCCCCGCCCCCCCCGAGCGACCGGCCGCCCTCGCCCCCGCCCCCGCACCGGGCCCGCCCGCCGGTCGCGAGCGAGTCGAGGACGTCGACGAGATCGCCGAGGGAGGCGAGCGGGCGTCCCCGACGGCCGACGACGCCGAACCGCCGGAGCCCCCGGAGCCGGAGCCGGCGACCGCCGACCGAGGCGCGACGGGAGCGTCGCGCGACGAGTTCTCCGACCAGAGCGACGTCGAGGACGGTTTCGGCCCGCTGCCCGAGTCCGTGTTCGAGGCGATCGAGGACTCCCAGGACGGGCCGCCGGGCGAGACGCCCCCGGCGGTCGCGCCGACTCCGCCCGCGGTCGCGGCGGCCGGGGCGGGCggggcggcgccggcgcgcgAGCGGCGGGTGCGCGCGTGCCCGACGTGCGGCAAGACGTACACGGCGGCGTCGTCGTACTTCTACCACGTGAAGCACGGGCACGCGCCGGCGGCGCACCGGCAGCACGCGTGCGGCGTGTGCGCGCGGCGGTTCGGCACGCGCGGGGCGCTGGCGGCGCACGCGTCGGTGCACACGGGCGAGTGCACGCTGGAGTGCGCCAGCTGCGGCAAGCGGTTCCGGTCGAAGGCGAGCCTGTACATCCACGAGCAGACGCACTCGGGCGTGAAGACGTGGCGGTGCGGGCTGTGCTCGCGCTCGTTCCGCTGGCGCGCGCAGCTGCTGCGCCACGCGGCGCGGCACGCGGGCGAGCGCACGCACGCGTGCTCGTCGTGCCCGCGCGCGTTCTCGGTGCGCTGCGACCTGCTGCGGCACGCGCGCACGCACGCGCCGCGGCCGCACGAGCTGGCGTGCGAGGTGTGCGGCGCGCGGTTCGCGCAGCCGCGCTACCTGCGCGCGCACCGGCTCAAGAAGCACGCCGCCGCGCAGCCGCAGGTGATCCTCAAGCCGTGA
Protein Sequence: MGNETEQIFLLNPAGAQSGSGLLLKAGEAQSSATVNLENVTDFSNVCRTCATITEFVIPIFEGEGLQNNLADKIHKHLPIQVSPHDSLPVVVCVQCASTLLAWHEMVACCEQADAALRTRHHVLHRTHAHVQPSTNHRKEAGAPAEEVENRSQTSVQFYTIVKNALSDHLHTLNVDEDDLDIELVCQKCPHRPAAASARALAAHLAAAHRLPPRAAAVARFLTRHLTFEETLRDTDSDSEPAPPAAPAPPAPPAPPAPLAAPPAEPPPLPHHRCPLCESVFSSGTRLRHHLNSHADRSVACCGALHADRAALLRHLRADHAHRPAHPPPAGALCRSCGHRADDAASLRAHIAEAHREDAEARAPPASAARRSADQKYVPADCPDCGATFSNKYNMSVHRRRHASDAPPPRHACDSCGRTYGSRAAAARHARLAHAGALPALCPHCGEAFPTRGERDTHARLHTGARPHVCPYCDKAYRAADTLRRHLDAHLDVRRHRCPRCPKTFRKSSHLRGHLAAACGRDRPARPARRRHYPDFTDSSDDSEPAGAAAAEADGFDDLTGRNMRGDRLDESTRRELGEARTRIGGRAYYSCRECGKTLGSAHTFVFHRRIHTGERPCVCHVCGKQFRAPNGLRRHLTETHERARRHACRHCPKSFANSQNLKQHLRIHTGERPYVCALCGKRFTQSGSLHVHAKTHSALQPHRCADCGAAFRLRAGLARHRLRHAAGAPPPTALPSAALPARAAPRPHVCSLCGAAFAQRRALRLHARRLHPAPPAPPDPPLYPSAALGAALARPVAVTVDGAGRRRAECGVCGRRVAPAGWRRHARAHLPDRPHRCDACGLGFADAGNLARHARAAHARARPHACRLCGAAFSRRAHLQDHERAHGSAREFVCDECGAASKSAAALRMHRRAHRAPGPPAGAPPCVQCGARFRRAGELRAHLSEEAAEPPPREPADPEPASGAARRCEFCAAEPPVALYADHLVDEHAHLVFHCDECDQYVPRRELFLHMTRHADQYVAAAERPAAPAPAPARPAALAPPERPAALAPAPARPAALAPPERPAAPAPPERPAALAPAPAPGPPAGRERVEDVDEIAEGGERASPTADDAEPPEPPEPEPATADRGATGASRDEFSDQSDVEDGFGPLPESVFEAIEDSQDGPPGETPPAVAPTPPAVAAAGAGGAAPARERRVRACPTCGKTYTAASSYFYHVKHGHAPAAHRQHACGVCARRFGTRGALAAHASVHTGECTLECASCGKRFRSKASLYIHEQTHSGVKTWRCGLCSRSFRWRAQLLRHAARHAGERTHACSSCPRAFSVRCDLLRHARTHAPRPHELACEVCGARFAQPRYLRAHRLKKHAAAQPQVILKP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -