Basic Information

Insect: Polydrusus pterygomalis
Gene Symbol: ZEB2
Assembly: GCA_963969555.1
Location: OZ018380.1:12427278-12432148[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 4.3e-05 0.008 18.7 2.2 1 23 53 75 53 75 0.98

2 26 4.8e-06 0.0009 21.7 1.6 1 23 81 103 81 103 0.98

3 26 0.0031 0.58 12.8 0.4 1 21 109 129 109 130 0.95

4 26 0.17 31 7.4 0.2 1 23 160 183 160 183 0.93

5 26 0.0008 0.15 14.7 0.3 1 23 189 212 189 212 0.97

6 26 7.4e-06 0.0014 21.1 1.4 1 23 217 239 217 239 0.98

7 26 0.00077 0.14 14.7 0.1 1 23 247 270 247 270 0.94

8 26 0.27 50 6.7 7.3 1 23 276 298 276 299 0.95

9 26 6.1e-06 0.0011 21.4 1.2 1 23 307 329 307 329 0.95

10 26 0.13 24 7.7 0.7 5 23 338 357 335 357 0.91

11 26 0.0095 1.8 11.3 2.1 2 20 363 381 362 384 0.93

12 26 8.1 1.5e+03 2.1 1.9 2 23 396 415 395 415 0.76

13 26 4.1e-05 0.0075 18.8 2.8 1 23 422 444 422 444 0.98

14 26 2.7e-06 0.0005 22.5 5.4 1 23 450 472 450 472 0.97

15 26 0.0057 1.1 12.0 2.4 3 23 509 530 508 530 0.96

16 26 0.0035 0.65 12.7 0.8 1 23 536 559 536 559 0.97

17 26 1.8e-05 0.0033 19.9 0.8 1 23 564 586 564 586 0.99

18 26 0.0028 0.52 13.0 0.1 1 23 593 616 593 616 0.93

19 26 0.0034 0.64 12.7 5.3 1 23 622 644 622 645 0.95

20 26 5.9e-05 0.011 18.2 1.2 2 23 654 675 653 675 0.93

21 26 0.00016 0.031 16.9 0.5 2 23 681 703 680 703 0.95

22 26 2.9e-05 0.0054 19.2 0.2 2 23 709 730 708 730 0.96

23 26 0.54 1e+02 5.8 0.3 5 23 742 761 741 761 0.71

24 26 7.2e-05 0.013 18.0 5.6 1 23 768 790 768 790 0.98

25 26 9.9e-07 0.00018 23.8 3.2 1 23 796 818 796 818 0.97

26 26 5.4e-06 0.001 21.5 1.4 1 21 824 844 824 845 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	4.3e-05	0.008	18.7	2.2	1	23	53	75	53	75	0.98
2	26	4.8e-06	0.0009	21.7	1.6	1	23	81	103	81	103	0.98
3	26	0.0031	0.58	12.8	0.4	1	21	109	129	109	130	0.95
4	26	0.17	31	7.4	0.2	1	23	160	183	160	183	0.93
5	26	0.0008	0.15	14.7	0.3	1	23	189	212	189	212	0.97
6	26	7.4e-06	0.0014	21.1	1.4	1	23	217	239	217	239	0.98
7	26	0.00077	0.14	14.7	0.1	1	23	247	270	247	270	0.94
8	26	0.27	50	6.7	7.3	1	23	276	298	276	299	0.95
9	26	6.1e-06	0.0011	21.4	1.2	1	23	307	329	307	329	0.95
10	26	0.13	24	7.7	0.7	5	23	338	357	335	357	0.91
11	26	0.0095	1.8	11.3	2.1	2	20	363	381	362	384	0.93
12	26	8.1	1.5e+03	2.1	1.9	2	23	396	415	395	415	0.76
13	26	4.1e-05	0.0075	18.8	2.8	1	23	422	444	422	444	0.98
14	26	2.7e-06	0.0005	22.5	5.4	1	23	450	472	450	472	0.97
15	26	0.0057	1.1	12.0	2.4	3	23	509	530	508	530	0.96
16	26	0.0035	0.65	12.7	0.8	1	23	536	559	536	559	0.97
17	26	1.8e-05	0.0033	19.9	0.8	1	23	564	586	564	586	0.99
18	26	0.0028	0.52	13.0	0.1	1	23	593	616	593	616	0.93
19	26	0.0034	0.64	12.7	5.3	1	23	622	644	622	645	0.95
20	26	5.9e-05	0.011	18.2	1.2	2	23	654	675	653	675	0.93
21	26	0.00016	0.031	16.9	0.5	2	23	681	703	680	703	0.95
22	26	2.9e-05	0.0054	19.2	0.2	2	23	709	730	708	730	0.96
23	26	0.54	1e+02	5.8	0.3	5	23	742	761	741	761	0.71
24	26	7.2e-05	0.013	18.0	5.6	1	23	768	790	768	790	0.98
25	26	9.9e-07	0.00018	23.8	3.2	1	23	796	818	796	818	0.97
26	26	5.4e-06	0.001	21.5	1.4	1	21	824	844	824	845	0.96

Sequence Information

Coding Sequence: ATGTTTCCTTCTTTAAAACTTATGCAGAAACATCAAATATGTCACACAGATAAAAGTAGAAAAGGCACcatattagaaaaatttccTTATTGCAGTAAGAAATACCTGCATGTAAAAGAACATATTAAAGATATCCATAAACGGGATAATAAAAACTTTGTTTGCGAACAGTGtggaaaacattttaaaagaaaaaatgaactTAAACCACATCTTATGATGCACCAAGAAATAAGACCACACCAATGCAATGAATGTGGCAAAAAAATTCGTACAAGTCAGAATTTAAAAGTACATATTCGTTGGCATACTGGGGAAAAGCCATTCGTGTGTGAAGTTTGTGGCGAAAGATTTGCTCACAGGCAGCCATTTAATAATCATAGGAAACTACAGGAGGAGTTTATCAAAATAGAATTTGACTATGGCGATTCAACTCAGCTTCTATTTGGCCCAAAAAAGGAACTTGCGTGCAAGACTTTCTTGTGTCCCTTTTGTAAAACAGGATTTGACGAGGACTACCAGTTGGCTGATCATTTGGCATCAAAACATTCTAAGGAGCCGCTGTATTCGTGTCAGTTTTGTCTAGAACCATTTAAGGCACAAGACAGCCTCAACAAACATATTGAAACTGACCATTATCGTACTGAAtttaaatgtacaatttgtgAACAAACTTTTACAGATAAGACGTCTTTGAAGCTGCATTTAGAAAGTCAtgatctaaataaaaaaaagacttATCCGTGTATAATTTGTAATCGTGAGTAtggtacaaaaaataatttgaatagaCACATTGCCACTATTCATCTGGATGAACGACCGTTTCACTGTGAAATTTGTGATAAGTGGTTCAAGACAAGCACTACTCTTGATCAGCATAAACACAGTCACCATCCTTTGGAAAGTACAATATTGTTTAAATGCGAAACTTGCGACAAAACATTCAAAAATGAAGCGAATTTAAAGGTGCACGAGACACAACATCTTAAAACCCCAAAGGTCTGTATAGTTTGCAATcaactatttaataataactctCGATTAAATTTGCACATGCAGCAAAGACATGCACCTCGTACGATTCCTTGTACCATTTGTGAGAAAATGTTTTCTACCGAGAAACTTATGCATAGACATCTAATATGTCACACAGATAAGAGTAACAAAGGCACCATATTAGAACAATGTCTTTATTGCAGTAAGAAATACCTGCATCTAAAAGAACACATTAGAGATATCCATCAACAGGGCAAGAAAAACTTTGTATGCGATCATTGTGGTAAATATTTCAGAAGAAGAAAGGAAATTAAGGAACATCTTATGATGCACGAAGAAATAAGACCACATGAATGCCACGAATGTGGCAAAAAATTTCGTACAAGACAGAATTTAAAAGTACACACTCGTTGGCACACTGGGGAAAAGCCATTCGTGGAGATTATCAAAATAGAATTTGACAATGGCGATTCCACTCAGCTTGTAATTGGTCAAAAAAAGGAACTTGTGCGTAAGATTCTGTTGTGTCCCTTTTGCAAAAGAAGATTTAACGAGAGCCACCAGTTAACTGATCATTTGGCATCAAAACATTCTAAGGAACCGCTGtatttttgtcaattttgttTAGAACCATTTAAGGCACAGGACACTCTTAACAAGCATATTGAAACTTTCCACTATCTTTCCGAATTTAAATGTAACATTTGCGACCGAATCTATAACGATACGACTTCATTGAAGCTGCATTTAAGAATCCATGATCCAAATAGAAAGACTTATCCGTGTATAATTTGTAATCGTGAGTATGGCACAAGAAATAATTTGAATAGACACATTGCATCTATTCATCTTGATGAACGACCGTTTCACTGTAAAATTTGTGATAAATGGTTCAATACAAACAGTGCTCTTAATCAGCATACTTACCGGCACCATCCTTCGGAAAATACAACTGTGTTGAAATGCGAAACTTGCGAAAAAACATTCAGAAATCAGCAAAATCTAAAATTGCACGAAGCACAACATCTCAAGTCCCCGAAGGTATGTCCAATCTGCGGacaactatttaataataactctCGATTAAATTTGCATATGCAGCAAAGACATGCACCTCGTACTattccttgtactctttgtgaTAAAATGTTTCCTAATTTGAAACTTCTGGAAAGACATCAAATTAGTCACACGGATAAGAGTAACAAAGGTACCATATTAGAAGAATGTCCTTATTGCAGTAAAAAATACCTGCAACTCAAAGAACACATTAGAGATATCCATCAACAGGGCAAGGATAATTTTGTGTGCCATCACTGTGGTAAatattttagaagaaaaaaggaaattaaGGAACATCTTATGATGCATCTAGAAATAAGACCACATGAATGCAACGAATGTGGCAAGAAATTTCGTACAAGACAGAATTTAAAAGTACACACTCGTTGGCATACTGGGGAAAAGCCATTCGTGTGCGAAGTTTGTGGCAAAAGATTTGCTCACAAGCAGCAATTTAATAAGCATATGAAACTGAAACAATGTCGCGCATGA
Protein Sequence: MFPSLKLMQKHQICHTDKSRKGTILEKFPYCSKKYLHVKEHIKDIHKRDNKNFVCEQCGKHFKRKNELKPHLMMHQEIRPHQCNECGKKIRTSQNLKVHIRWHTGEKPFVCEVCGERFAHRQPFNNHRKLQEEFIKIEFDYGDSTQLLFGPKKELACKTFLCPFCKTGFDEDYQLADHLASKHSKEPLYSCQFCLEPFKAQDSLNKHIETDHYRTEFKCTICEQTFTDKTSLKLHLESHDLNKKKTYPCIICNREYGTKNNLNRHIATIHLDERPFHCEICDKWFKTSTTLDQHKHSHHPLESTILFKCETCDKTFKNEANLKVHETQHLKTPKVCIVCNQLFNNNSRLNLHMQQRHAPRTIPCTICEKMFSTEKLMHRHLICHTDKSNKGTILEQCLYCSKKYLHLKEHIRDIHQQGKKNFVCDHCGKYFRRRKEIKEHLMMHEEIRPHECHECGKKFRTRQNLKVHTRWHTGEKPFVEIIKIEFDNGDSTQLVIGQKKELVRKILLCPFCKRRFNESHQLTDHLASKHSKEPLYFCQFCLEPFKAQDTLNKHIETFHYLSEFKCNICDRIYNDTTSLKLHLRIHDPNRKTYPCIICNREYGTRNNLNRHIASIHLDERPFHCKICDKWFNTNSALNQHTYRHHPSENTTVLKCETCEKTFRNQQNLKLHEAQHLKSPKVCPICGQLFNNNSRLNLHMQQRHAPRTIPCTLCDKMFPNLKLLERHQISHTDKSNKGTILEECPYCSKKYLQLKEHIRDIHQQGKDNFVCHHCGKYFRRKKEIKEHLMMHLEIRPHECNECGKKFRTRQNLKVHTRWHTGEKPFVCEVCGKRFAHKQQFNKHMKLKQCRA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -