Basic Information

Gene Symbol
-
Assembly
GCA_935413225.1
Location
CAKXYS010000333.1:345804-369205[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.017 1.7 10.5 0.1 3 21 515 532 513 533 0.89
2 13 0.00036 0.037 15.8 1.5 1 21 540 560 540 561 0.95
3 13 0.25 25 6.8 0.7 1 23 571 592 571 592 0.95
4 13 0.0037 0.38 12.6 3.3 1 23 595 617 595 618 0.93
5 13 8.5 8.7e+02 2.0 0.3 2 23 628 650 627 650 0.74
6 13 1.6e-05 0.0016 20.1 2.2 2 23 660 681 660 681 0.98
7 13 0.0043 0.44 12.4 0.1 1 23 686 709 686 709 0.94
8 13 0.0059 0.61 11.9 6.6 2 23 716 737 716 738 0.95
9 13 0.00075 0.076 14.8 1.5 1 21 1299 1319 1299 1320 0.95
10 13 0.19 20 7.2 3.0 2 23 1348 1369 1348 1370 0.94
11 13 0.098 10 8.1 1.7 1 23 1399 1421 1399 1421 0.97
12 13 0.19 20 7.2 1.8 3 23 1430 1451 1428 1451 0.96
13 13 0.00037 0.037 15.8 5.2 1 23 1459 1482 1459 1482 0.98

Sequence Information

Coding Sequence
ATGTCTGGGGAACGATGCCGACTGGGGTGTCTAGTAGATCGGTGTCCCAACAATcagaaaagaaaaaaacgaaACACAAAAGAAGTAAAATATTACCCATTTCCTGATGAGCTAATTACGAAGGAAATatggataaaaatattaagtttagtTGGTTACACCAAAGAGAATAATGCCAATATTTGCTCGATACATTTTCTAGAAAGTGATTTTGAAGTAAATGAAGTTGGAAAATTTGTATTGAAAATAAATGCGGTACCTTCAATAAATTTGGATCTGGTTCTTTTAGGCAATGAAGTAGTTATAAAAACCATTGCAAGTACAGAAGACACATTAAATGTTGGTGTTTTAAGGAATGAAACACATAGACTCGAAATCATTCATAAACACTCTGAAGATACAAATCTGTCTTATGACTTTCTGAATGcccttaaaaaatcattttccaATACTGAATATTGTAAAGACTATAGTTTGCAGCTAGTTTCTACATGTCTCGATGATAACTTGCTTGAAAATGTGATAACTGCTGCTAAGAAAAACCAGATAAGtactttaaaaaatctaaaaatttctacaaaagGAGaagaGACAGTGGCACTCGAGAGAGAGGAAGAATTAGAGAAAGGAGACAAAAATACACCTCAAAGTTGTCTTAATAATTCTTTCTTCAGTGATCTGGAAAATAACCATGAAGATTCTGCAATAATAGAACCCAACTTTAACGAAGCGCCATATTCACTCTTAAacaaatttgaagataattttgcAACGCATATGGATAGTAAAATTACGAACGAATGTTATGAAGCGAATGAAATAATGGATGATTTGAAAGACCAGCAAAAAGATGTTCTTAGTAAAGTTGTAAAGCTGCTGGTCCCAGTAAAATCTGCAAATGACTTAGTATGTTTAGAGGCTTCTAATGAaaatgataaagttatatcactTAGAACAGACGATTTTTCTGTAAGAAATAAATCCGATTTCGATTCAGCAAATGGAAAAGATTCGCATTTACGAAATATAGATTTCGTAAATATAAAGTCTGATGCAGAATTAACCATAAAATGTGAAGAAAGTAATGATATAACAGATAATGACCAATACGTTGAACCAATAGAATTAGTTCATGTCAGATACGAAGATTCCTGTACTCCAATTAATCATGTAAATTCTGAGGAGACATATGTAAATAACGATTTTATCATTAGCAATATTGATAAcgacgaaaaatattccttaccCATCAATTCTGCGGATAGTGGGGTGAATAGGAACCCATCTGTCACAGaattaattttaagaggtcaactTGATAAAACATCTTGCACGTATCCTAGCTTAACAGTGATTACTCCACCGATTTTAAATCCGGAAGATATAGCGGCcgatttttccgaaaatttgaAAGTTGTGTCTTTGGATTTTAATATGGCTATAGAAAAACGAATTATATTTCTGGGAGGAATGTATTGTGGTTATTGTATGAAGACCAAGGGAGCGTGTCGATGTTTTAAATTAAGTCAACGACCGGTAATATGCGAGAAATGCGGTAAAAAATTTACAGggtcTGCACTAAAGAAGCACGCACTCACATGTAATTCCGATTTATGTTTTACTTGTGAAAAATGCAACGCTACGTTTTCAACTCAAAGTAAATATGAAAGTCACTTAAAGAAAGTTGCCGATGCTCCTGTTTGTAACTACTTCAAatgtaaaatatgttttgttaaATTTAGCGAGGAAGGCTTCAAAGAACATATTATAGAGCACCCAAACTACCTCTGCCAAAATTGTGGTAAATCGTATATTAGTTATAAAAAGTTGTATAGTCACGTAAGAAATCACCATCCCGATCCTAACCAAGAAGCAACTGTGGTTTGTCAGTTTTGTGGAAAACTGGTTTCTACGAAAGGCCTTTCTTTAAAGCAACATTTAAAAGCTCATGATTTACATAAACAAGGGAAAAAAGaAACATGTGATATTTGCAATAAAAAGTTCTATACTAAATGGGATCTTCGGAAGCATAAACGGATCCATTCTGGGAATAAGTATTCATGTGATCTTTGCGATAAGAAATTCTCATCTCCGTTGGGTGTAAAGGTGCATTCtcaGGTCGTGCATATGAAAAAACCCCTTGCCACTTGTGAAATTTGCCACAAGGAGTTTACAAGGCGTGATTATTATCGGTTCCATATGCGCCGGCATCATGCCGGTAATGGTCCTCCAATGGCCACATCTACACGGGTACCTGGTGGACGAAAAGGGAAAACCAGAAAAAATCCTTCATCGAGACATAAATGTCGATTGTGCAATATGACTTTTCAATGTGCGAGTAATAGAGATAGACACGAAAAGCTCCATGAAAATCCTTATTACGAATTTAGATTTCCTGATGATCCAATTTGGAAGAAAAAATGGGTAGAAATATTATGTTTAGTTGGTTATAACAATAAGAAGAATGCCAATATTTGCTCTAtacattttctagaatatgatttcgAAGTAAATGAAGTTAGAAAATTTCTATTGAAAAGAACTGCCATACCTTCAGTGAATTTGGATTTGACTCTTTTAGGCAACAAAGTTGGTGTAGTTAACATTGCAACTACAGAGGACACATTAAGTGTCGGTGTTTCAACGAATAAAACATGTGAACTTGAAAATatgtgtaaaaactttgaatatGTAGATTTTTCCTATGACTTTCTAAATACCCTTAAGAAATCATTTTCCAATACTGAATATTGTAAAGACTATAGTTCTCAGCTTATTTCTACATGTAATGATGATAATTCACTTGAAAATATGATAACTGCTGCTAAGAAAAACcagataaacattttaaaagatcTTAAAATTTGTAACTTCAACTATAAACAACAgagATTGTATTTGTACAAGCAAGAGGAAAAGAATCAAACATATGCTAAAATAAAAACTCCTTGTTTTGGAAGATGCAGTGATATGGGAAATAACCGCGAAGTTTCCACACCAATAGAACCCATTTTTAATGAAGCTCCGCATTCTATCCCAAACAATTTTAAAGATACAGCAGACAGTATTGAAAGTCAAGCTACGAAAAAATGTGATgaagaaaatcaaataactAACATTTTGCATGACCAACAAAAAGAtattattagtaaaaatataaCTCTTCTAGCCCCAATAAAATCTGCTGATGATTTAGTTAGTTTGGGGGCTTCTAGTAATAGTGCCCtctataataataagtttaatgATATGATTGATTATAAACAAGTTTCTAGTTATCTTTTAGGCATCAATCACGGCAATGGTTTTAATGAACCACAGGAAAACCAACTAGATCAAATAAATACAGAGAGTGAAAGCGATGTCGTACCTTATAATTTTGGAACAGACGGTTTTGTAAGTTTTCCAGCAGATTTTTCAGAAAGACATGAATCCAATTTTGATTCATCAAATGGAAACGATTCACATTTAAAAGATTTaagttttataaacataaaatctGATGTAGAAGTAACTAATCTACTAGGAGCTATAAAATCTGAAGAAACCGATTTAATAGATATGGACCAATACATTAAACCAGATGATAATATGAAATGCAAAGATCTGTGTACTTTAAATAATGAGGTAAATTCTGGGAACTCATATGTTAATGATGATTTTATAATGAGTGATAATGATAAttctacagaaaaaaaatattccgttGGCTATGTCAGTTCCGCGCATAGCGGGGTGGATCTGAACATGTCCGTCACGGAATCAATTTTAAGAAGTGAATTTAATAACATATCTGGCTCGTTTCCTAGCTTAACAGTAATTACTCCGCCGATGTTAAATCTAGAAGgctgGTCATTAAGAAGGCACGCACTTATATGTCAACCTGGTTCAAGCTTTACATGTGAAAAATGCAACGCTACTTTTTCATCTAAAAGTAAATATGCAACTCACTTAAAGAAAATTGCAGATGCTCCTGTATGTAACTACTTCAAATGTAAAATATGTTTGGtaaaggTTGTGCATATAAAAAAGCCTATTGCCTCTTGCGAAATTTGCAAACTGGAGTTTGCTAGACATGATTATTATCGGTTTCATATACGTGTCCATCATGCTGGCAACGGTCCCCCAATGGCCACATCTACGCGGGTACCTGGTGGACcaaaaAGAAAAATCGGAGAAAATCATCCATCCAGACATAAATGTGGATTGTGCAATATGACTTTTCAAAATGTGGGTAATAGGGAAAGACATGAAAAGCTGCACGAAAATCCTTATTACCAATTTGGCTGCAAAATATGTCATGCCCGAAACAAGTCCGAAGAACAACTGCAGCGGCATATGGAAAAATCCCACTCGAAAATACCGAATAAAATTTATCAATGCTACCATTGTAACGAACAGTTTAATAAGAAGTATTTCTTACAAAATCATATGCGTAATGTGCATTCAAGAGTACAAACTGGGGGCGAGGATAGAGCAAAATCGGGAAATGAAAGAAACGAAACTGTTAACAAATCAGTAATTTga
Protein Sequence
MSGERCRLGCLVDRCPNNQKRKKRNTKEVKYYPFPDELITKEIWIKILSLVGYTKENNANICSIHFLESDFEVNEVGKFVLKINAVPSINLDLVLLGNEVVIKTIASTEDTLNVGVLRNETHRLEIIHKHSEDTNLSYDFLNALKKSFSNTEYCKDYSLQLVSTCLDDNLLENVITAAKKNQISTLKNLKISTKGEETVALEREEELEKGDKNTPQSCLNNSFFSDLENNHEDSAIIEPNFNEAPYSLLNKFEDNFATHMDSKITNECYEANEIMDDLKDQQKDVLSKVVKLLVPVKSANDLVCLEASNENDKVISLRTDDFSVRNKSDFDSANGKDSHLRNIDFVNIKSDAELTIKCEESNDITDNDQYVEPIELVHVRYEDSCTPINHVNSEETYVNNDFIISNIDNDEKYSLPINSADSGVNRNPSVTELILRGQLDKTSCTYPSLTVITPPILNPEDIAADFSENLKVVSLDFNMAIEKRIIFLGGMYCGYCMKTKGACRCFKLSQRPVICEKCGKKFTGSALKKHALTCNSDLCFTCEKCNATFSTQSKYESHLKKVADAPVCNYFKCKICFVKFSEEGFKEHIIEHPNYLCQNCGKSYISYKKLYSHVRNHHPDPNQEATVVCQFCGKLVSTKGLSLKQHLKAHDLHKQGKKETCDICNKKFYTKWDLRKHKRIHSGNKYSCDLCDKKFSSPLGVKVHSQVVHMKKPLATCEICHKEFTRRDYYRFHMRRHHAGNGPPMATSTRVPGGRKGKTRKNPSSRHKCRLCNMTFQCASNRDRHEKLHENPYYEFRFPDDPIWKKKWVEILCLVGYNNKKNANICSIHFLEYDFEVNEVRKFLLKRTAIPSVNLDLTLLGNKVGVVNIATTEDTLSVGVSTNKTCELENMCKNFEYVDFSYDFLNTLKKSFSNTEYCKDYSSQLISTCNDDNSLENMITAAKKNQINILKDLKICNFNYKQQRLYLYKQEEKNQTYAKIKTPCFGRCSDMGNNREVSTPIEPIFNEAPHSIPNNFKDTADSIESQATKKCDEENQITNILHDQQKDIISKNITLLAPIKSADDLVSLGASSNSALYNNKFNDMIDYKQVSSYLLGINHGNGFNEPQENQLDQINTESESDVVPYNFGTDGFVSFPADFSERHESNFDSSNGNDSHLKDLSFINIKSDVEVTNLLGAIKSEETDLIDMDQYIKPDDNMKCKDLCTLNNEVNSGNSYVNDDFIMSDNDNSTEKKYSVGYVSSAHSGVDLNMSVTESILRSEFNNISGSFPSLTVITPPMLNLEGWSLRRHALICQPGSSFTCEKCNATFSSKSKYATHLKKIADAPVCNYFKCKICLVKVVHIKKPIASCEICKLEFARHDYYRFHIRVHHAGNGPPMATSTRVPGGPKRKIGENHPSRHKCGLCNMTFQNVGNRERHEKLHENPYYQFGCKICHARNKSEEQLQRHMEKSHSKIPNKIYQCYHCNEQFNKKYFLQNHMRNVHSRVQTGGEDRAKSGNERNETVNKSVI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-