Basic Information

Insect: Polydrusus cervinus
Gene Symbol: ZFHX3
Assembly: GCA_935413225.1
Location: CAKXYS010000473.1:778890-797406[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.8 82 5.2 0.2 1 23 34 57 34 57 0.88

2 15 0.099 10 8.1 0.8 2 23 75 97 74 97 0.93

3 15 4.7 4.8e+02 2.8 2.4 2 21 176 195 176 199 0.87

4 15 0.084 8.6 8.3 1.3 1 23 212 237 212 237 0.92

5 15 0.0062 0.64 11.9 1.6 1 23 255 277 255 277 0.97

6 15 0.0014 0.14 14.0 0.7 2 23 284 306 283 306 0.94

7 15 0.00074 0.076 14.8 3.0 1 23 415 439 415 439 0.92

8 15 0.011 1.1 11.1 0.6 1 22 459 480 459 483 0.89

9 15 0.0021 0.22 13.3 0.2 1 23 532 556 532 556 0.93

10 15 0.0022 0.23 13.3 0.0 2 21 621 640 620 641 0.93

11 15 1.1 1.1e+02 4.8 1.4 2 19 775 792 774 797 0.90

12 15 0.00023 0.023 16.4 2.5 1 23 1372 1394 1372 1394 0.99

13 15 0.0012 0.12 14.2 0.3 1 23 1493 1515 1493 1515 0.98

14 15 0.012 1.3 10.9 0.4 2 23 1667 1689 1666 1689 0.96

15 15 3.8 3.9e+02 3.1 3.5 3 23 1951 1973 1950 1973 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.8	82	5.2	0.2	1	23	34	57	34	57	0.88
2	15	0.099	10	8.1	0.8	2	23	75	97	74	97	0.93
3	15	4.7	4.8e+02	2.8	2.4	2	21	176	195	176	199	0.87
4	15	0.084	8.6	8.3	1.3	1	23	212	237	212	237	0.92
5	15	0.0062	0.64	11.9	1.6	1	23	255	277	255	277	0.97
6	15	0.0014	0.14	14.0	0.7	2	23	284	306	283	306	0.94
7	15	0.00074	0.076	14.8	3.0	1	23	415	439	415	439	0.92
8	15	0.011	1.1	11.1	0.6	1	22	459	480	459	483	0.89
9	15	0.0021	0.22	13.3	0.2	1	23	532	556	532	556	0.93
10	15	0.0022	0.23	13.3	0.0	2	21	621	640	620	641	0.93
11	15	1.1	1.1e+02	4.8	1.4	2	19	775	792	774	797	0.90
12	15	0.00023	0.023	16.4	2.5	1	23	1372	1394	1372	1394	0.99
13	15	0.0012	0.12	14.2	0.3	1	23	1493	1515	1493	1515	0.98
14	15	0.012	1.3	10.9	0.4	2	23	1667	1689	1666	1689	0.96
15	15	3.8	3.9e+02	3.1	3.5	3	23	1951	1973	1950	1973	0.89

Sequence Information

Coding Sequence: ATGAACTCCGACCTCTCCCAACTCGACAATCCCCATCAAGTCAAATCCGAACCCAACGACCTCGAAGAACCAAACCACCTGGACTCAAACCCAGGTCCACACATGTGTCCTTACTGCGACTATTCCAGTGATAGCGAAATGCGAATCCAAGCTCACATCCTAGCTCAGCACGGTTCCAATCATCCTGGTAACATCCAGCAACCTCAAGAACAGCAGGTGATCCATTGCCCGTTATGCCAGGACTTATTTAAAGACAGGAGTAAGCTGGAACGACATGTTATGCAGATCCATTCGGTGAACAGCGAGGGTTTACAAAGATTGTTAATGCTGGTGGATCAAAGTCATTGGTTGAATCAAGCGTCGAGGACGTCTACGCCGAATAACTCTTCTATGGCTGTACAAAATCAAGTTTCTCCGACCTCAGTGTCTTCCAAAGACTCGCAGAAGCTAGACAAATGTGAAAATGAAGATAATCCTGATCTTTTGTCGCCTATTAGCGATGATGCCGTCGAGAGTGAAAGTGAAAGATGTAGCACGTGCCTTAGAACCTTTCGAAACGTCGATGAACTTTGCTTTCATCAAAACGAGACTGGTCACCAGCTTGAAGTCAAGCAGACACCTAGTGGACCAGGGTATGTGTGCTGGAAGAAAGGCTGTAACCAGTTTTTTCCTACCGCTCATACGCTACAAATGCACTTTAAGGAAATACATGCAAAGAACTCCGTTGCTAATATGTCTGTTAGTGAAAAGCACGTCTACAAATACCGTTGCAATCAATGCTCTTTAGCGTTTAAGACTTTGGAGAAATTACAACTTCACTCGCAGTATCACATGATAAGAGATGCTACAAAATGCGTTTTGTGTGGACGCAGCTTCAGATCGCTAGTAGCTCTTCATAAACACGTTGAAAGCGTTCATTCGGAACTGACAGATGAAGAACTGAACGCTTACAAGCATAGCTTAATGAACAATCCTCTACTCTTAGCAGGATTACAAGGGCAAATTTTGGATAGTTCCACAAATGACTTATTGAAAAAGGAAAGCTTGCGAGGAGAAGAAAACGAGAGCACTGAGTGCGATGAAAGTAAGGACTTGAGTACAAGTCAATCACTCGACGATAGTAATCAAAATGACGGGGAGAATTCAGATGATAGCATTGTCTACAAAGACCAACAGTTCCTGGAAGACTACCTTAACAGCCAGGCCATGGCCGAAGATAGTTACAATGATCCCAATAGAAAGTACAAGTGTCATCGGTGTAGGGTTGCATTTACTCGACAAAGTTATCTTACAGCTCATAATAAGACGTTGCTGCATAGGAAAGGTGAAAAGCTCAGCTATCCCATGGAAAAGTACCTTGATCCTAATAGACCGTATAAATGTGACGTATGTAAAGAAAGCTTCACccagaaaaacattttgttggTCCACTACAATTCGGTCAGtcatttacataaattaaaaaggGCCATGCAAGAGCAGGCTAACAATAACAACAACCCTCCTGTCTCACCTATTATAGGTGCGACGCAGGCGCAAAACTTGTCCCTGACCCCGAAGAGCACGAGTAGCGAGGATGATGACAAGAAAAAATACCGGTGCAATATTTGTAAAGTCGCTTATACACAGGGCAGTACACTGGATATTCATATGAGGAGCGTCTTACATCAAACGAGAGCAAGTAAGCTGCAAGATCTCGCTCTAGCAGGGCAGATAGATCTGTCAAAGCCTTTAATAGAGCAGCCCGAAGTAGTGCAGTCGCCGAAACAACCCTCGCCGACGCCGAATGGAGGGGAGCTGGCCAAACAACCCTGCCCCACCCCGCCGTCTCCTTCAGGTACGTCAGGTATTCAAGGGATGAGTTGCGCGAAGTGTGGCGCGCCCTTTGCGAACCAAGATCAGTTGAACGCTCACCAGCTGTACTGTCTCTTCGCTGCGCCTATGGCCGTTTTGCAAGGTGCGAGCGATGACAGACAAGAGTGCGATCAAGACGTACAGTCTCGCGTAATGTCTGCGAAAAAAGGATCGCCGATTTATAAACATTTGCTTGAAGGTTACGGTTTCGATCTAGTAATGCAGTATAATGAGAGCCACCAGCGGAGACAACGACAGGCTGAAAAAGAAAAAGCTGAGGCAGAACTAAAGTTAAAGGAAGGTGCAAGTGGAAATCATAGTGTAGTTAGTGAGGAAAACATGCCTGATAACCACCAGGAAGTAAACGAAAGTGAGGAGATTAGAGAGGAAAGGGAGGAAGAACGAGAGAAACAAATTACCAACGATAAAGATGAAGACTTGGCGAGTCTGCCCGAAGTGAGTAAATCCACGTGCCAAACTTGCAACAAAGAGTTTTCGAGTGTGTGGGTGTTGAAGAGTCATTGTGAGGAAGTGCATAAAGACCTTGTACCGCTGGAATATCTCGAAAAATACGCGCAACAACTCAAAAatgaaatcgaaaaaaaaactgtcgtGGTTACCGCGGCTACGAGTTCGACAACGAGTGCTTTACCCCGTGTCACTACTCCTACGGGTGGAAACTCCAGTCCTGCGGCCGAAACTACACCTGATAAAGACCAAGAAGACAACAAGGATGCCCTTCACGTTAAGCTCAATCTCCAAACACCTCCTGAAGCGGCATCTACTGCTCCTAGCACGCCTACAAGCAGTAGTACCCCTGCTAGCTCTACTGATTCCTTACCAGCGAACATCCAAGCCATGCTTGCTCAGACTATGGCTCAGAATCCCATGGCTTTGGCTCAACAAATGTCGGAAATGCAAGCGGCGTTGAACGTGATGCAACTTCAACAGTTAAACTTTAACCCTGTGATGCAAATGATGGGGATGGGACTACCGTTGGGGCTTAATGCTTTGGCTGCTATGAATTTACAACCTCCTTTGGTGCCATTAATGATGCCCCCTCCTCCGTATGATCCGATGGGACAATTTGGACCGCAGGATCAGCAGGCTATGATGGCTAAGCAGCAGGCTGCTATGATGCAACAACAAGCGGTCGCAAATGCAGCAGCCAATCAAAAACGCGCACGAACTCGCATCACCGACGACCAGCTCAAGATCCTCAGAGCTCACTTCGATATCAACAATTCGCCCTCGGAGGATCAAATCCACGAGATGGCCAGTCAAAGCGGCCTTCCCCCCAAAGTGATTAAGCATTGGTTTCGAAACACCCTTTTTAAAGAAAGGCAACGGAACAAGGACAGTccgtataattttaataatcctCCGTCTACCACTTTAAATCTTGAGGAGTACGAGAAGACTGGCGAAGCTAAGGTTCAAACGTTGAATAGCTCTTCTGGCAGTAGCTGTGACGAAGctaataaaagtaaagattCCGCTTCGCCTCTACAAATTCCTGTTGTGCATCAGCTGGCAGAAGTAAAGCAGGAAATTAAAGAGGAGCCTACGGAAGACCACATGCTTCATCAGCCAAAATTTGACTTGAAGCCAAACGACTCTCTGGAAGAGAAAActcaaaatatgtttaatcTTCCCCCAAACTTGCAACCGCCCCAAAGCCCAGCAACATCAGTGGCTTCCATCGAGAGTATGAACGTTTCCTCACAACCCACCACTCCCACTAACCTCACGTTGAGTTCTATCATCGCATCACAACTCGGAGACACTCTAACTACCAGTACACCGACTCTAAACATGGCTGGGCTACAATCGCACCATGGTTTGACTAGTCCAATGTTACCGCCGCCAAAAATGAATCAGCAAAATTTTTCTAATCCAAATAACTTGCCTAGCTATCCATTGACTCCTAATAGGTGCTTAAGTCCCAGTCGGGAATACAGTAACCCTGGTAGCCACGGTTCTTGTGGATCATCTGGTAAGCGAGCGAACAGAACGAGGTTTACAGACTACCAAATTAAGGTTTTGCaagagttttttgaaaacaacGCTTATCCTAAAGATGACGATCTGGAGTACCTTTCCAAGCTTCTAAATCTTAGTCCTAGAGTAATTGTTGTTTGGTTTCAGAACGCCAGACAAAAGGCAAGAAAGGTTTATGAGAATCAGCCTGCTGCTGAACCAGCGCCTGGCATCGACGAATCTGGAGCGAACAGATTTCAAAGAACGCCCGGTTTAAACTATCAATGTAAGAAATGTCTTCTGGTGTTCCAAAGGTATTATGAGTTAATAAGACATCAAAAAACTCATTGTTTCAAAGAAGAAGATGCTAAGAGAAGCGCTCAAGCGCAAGCTGCAGCAGCTCAGATAGCTGCAGTGCTTAGCTCTGAAGACTCTAACTCTAGTACAACTGTAGAGCAAAATCAACAGCAACAAATGCAAACTCAACCTCAAAATTTAATGACAACTCAATCTAGTCAAGGATCTACTAACCAAACGATGAGTCCTGGACCGCCAAACCCTCCTACAACCCCAACTCCCAGTCAAGGAGGTGGAAATTTTCCCAGTTCGTCACCAACTCCTTCCGAAACTAAAGAAGGCACCTACCAGTGTGATAAATGCAACCTGGTATTCCCCAGGTTCGAGTTATGGAGGGAACATCAGTTAGTCCATCTTATGAATCCAAATTTATTTCCCGCCTATCCACCAGATAGTCCTTTTGGAATCTTACAACAACACGCTCAGTTGCAACAGTTAAATGCTAATTTGGGGGATGTTTCGAAGCAAAATAACCAAGCTGGACAATCTCCAAGCGTGCCAcaccctttaattaatatgtTGAATAATGTTACTGGGCAGAAACGTAAAATTGAGGAGTTTGGTGACGTGGAGAGTGATACCTCGGATCAACCGAAAGACAAAAGACTTAGAACTACTATTCTACCAGAACAGCTAGACTATTTATACCAAAAGTATCAAATTGAAAGTAATCCTTCTAGAAAGATGTTGGAAAGCATAGCACGAGAGGTAGGACTTAAGAAACGCGTAGTACAGGTTTGGTTTCAAAACACGAGAGCTAGAGAAAGGAAAGGGCAATTTAGAGCGCACGCGCAAGTAATCAACAAACGATGTCCTTTTTGTCCGGCGCTTTTTAAGGTTAAGAGTGCACTAGAGTCGCATTTAACTACAAAGCATGCCGACCAATGCGCTAGAGGAGACATCAACATTGATGCCCTACCCGACGAAGAAGTTAGTCTAGAAAGTGCTCCAAGTCTTTCTGGAGGAAGTGAAAACAAATTTCAGcagcaaaatcctaacttaatgcCTCCTTTATTTCCTAGTTTGCACCCTGATATGGAAAATTCGATCAAGAAATACTATGAAGAAAGCATGAAAAGATATATCAGCGAGCTTCAACAACATGCATCTTCCTCCAATGGCGACAAGAGTGAAATCAAGACCGAGAAAGGCGAAGGCGGAGAAATCCCTCTAGATCTCTCCAAACCCGTTGATCTTTCCAGGCCAATGAAGGTATCTATGGAGCACGGAAATCTTTGTGATCCAGGACCTTTAACCGACCTGAGTGAGCGATCACTTTGTGACGAACGTAGTGACTCTATGTCAGAGACAACCGAGTATTATGATGACGAAAGCAATCCTACCTCTCCAGCAAGTAGTACTCAAAGTGTTACTCAAAGACACCAATTAAATACTTCAGGAGGATCTCAGCATGGAGGGAACAAAAGATATCGTACCCAGATGAGTTCCGTACAAGTTAAAAtcatgaaatatttatttgctgACTATAAAACTCCTACCATGGCTGAATGTGAGAGTTTAGGAAGAGAAATCGGACTTCCCAAGAGGGTAGTGCAAGTGTGGTTTCAAAATGCACGAGCCAAAGAAAAGAAGGGGAAAATCGCTCTACAAAAGGTCCTGGGGCAACCTGAGAGCGACAATCCCCAACTGCCAGAAGACTGCAGGTTTTGTAACTTCAAGTACTCGCATAAATATTCTATTCAAGACCATATCTTTACCAAAAGCCACATTGGCAATATCCGCATGCATCTAGAGGCTCAAGGGAATAAAGAATGTCACGAGGGGAATGAGTTCCAAGTGCCTCAACTTCCTGGAGGCTCGGGGGGGATTAACGCTGACTCCACGACCAATAACCAAGCGGGAAATCAACAAATGCAACAGTCACCTAACAACCAAAACCAGTTGAACAACAACACGCACCTTCAACTTCTGCAAATGGCGGGGATTCCGATACAAGGCACCAAGACTCCCGAGCAGGAGGAAACTGCAGAGAGCCTGTTTCAACAATTGTACGCGTTGGGGAACAACTCTAATTTTGGGGTACAAAACCAGTACGTGCACCACGCTATGTTTGGAGCGAACGGTGAGTTctatgttgtatttttttag
Protein Sequence: MNSDLSQLDNPHQVKSEPNDLEEPNHLDSNPGPHMCPYCDYSSDSEMRIQAHILAQHGSNHPGNIQQPQEQQVIHCPLCQDLFKDRSKLERHVMQIHSVNSEGLQRLLMLVDQSHWLNQASRTSTPNNSSMAVQNQVSPTSVSSKDSQKLDKCENEDNPDLLSPISDDAVESESERCSTCLRTFRNVDELCFHQNETGHQLEVKQTPSGPGYVCWKKGCNQFFPTAHTLQMHFKEIHAKNSVANMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHMIRDATKCVLCGRSFRSLVALHKHVESVHSELTDEELNAYKHSLMNNPLLLAGLQGQILDSSTNDLLKKESLRGEENESTECDESKDLSTSQSLDDSNQNDGENSDDSIVYKDQQFLEDYLNSQAMAEDSYNDPNRKYKCHRCRVAFTRQSYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQANNNNNPPVSPIIGATQAQNLSLTPKSTSSEDDDKKKYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLALAGQIDLSKPLIEQPEVVQSPKQPSPTPNGGELAKQPCPTPPSPSGTSGIQGMSCAKCGAPFANQDQLNAHQLYCLFAAPMAVLQGASDDRQECDQDVQSRVMSAKKGSPIYKHLLEGYGFDLVMQYNESHQRRQRQAEKEKAEAELKLKEGASGNHSVVSEENMPDNHQEVNESEEIREEREEEREKQITNDKDEDLASLPEVSKSTCQTCNKEFSSVWVLKSHCEEVHKDLVPLEYLEKYAQQLKNEIEKKTVVVTAATSSTTSALPRVTTPTGGNSSPAAETTPDKDQEDNKDALHVKLNLQTPPEAASTAPSTPTSSSTPASSTDSLPANIQAMLAQTMAQNPMALAQQMSEMQAALNVMQLQQLNFNPVMQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPYDPMGQFGPQDQQAMMAKQQAAMMQQQAVANAAANQKRARTRITDDQLKILRAHFDINNSPSEDQIHEMASQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVQTLNSSSGSSCDEANKSKDSASPLQIPVVHQLAEVKQEIKEEPTEDHMLHQPKFDLKPNDSLEEKTQNMFNLPPNLQPPQSPATSVASIESMNVSSQPTTPTNLTLSSIIASQLGDTLTTSTPTLNMAGLQSHHGLTSPMLPPPKMNQQNFSNPNNLPSYPLTPNRCLSPSREYSNPGSHGSCGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLNLSPRVIVVWFQNARQKARKVYENQPAAEPAPGIDESGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTTVEQNQQQQMQTQPQNLMTTQSSQGSTNQTMSPGPPNPPTTPTPSQGGGNFPSSSPTPSETKEGTYQCDKCNLVFPRFELWREHQLVHLMNPNLFPAYPPDSPFGILQQHAQLQQLNANLGDVSKQNNQAGQSPSVPHPLINMLNNVTGQKRKIEEFGDVESDTSDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLESIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLTTKHADQCARGDINIDALPDEEVSLESAPSLSGGSENKFQQQNPNLMPPLFPSLHPDMENSIKKYYEESMKRYISELQQHASSSNGDKSEIKTEKGEGGEIPLDLSKPVDLSRPMKVSMEHGNLCDPGPLTDLSERSLCDERSDSMSETTEYYDDESNPTSPASSTQSVTQRHQLNTSGGSQHGGNKRYRTQMSSVQVKIMKYLFADYKTPTMAECESLGREIGLPKRVVQVWFQNARAKEKKGKIALQKVLGQPESDNPQLPEDCRFCNFKYSHKYSIQDHIFTKSHIGNIRMHLEAQGNKECHEGNEFQVPQLPGGSGGINADSTTNNQAGNQQMQQSPNNQNQLNNNTHLQLLQMAGIPIQGTKTPEQEETAESLFQQLYALGNNSNFGVQNQYVHHAMFGANGEFYVVFF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00196690;
90% Identity: iTF_00196690;
80% Identity: iTF_01238386;