Basic Information

Gene Symbol
-
Assembly
GCA_935413225.1
Location
CAKXYS010000076.1:6115-16440[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 4.2 4.3e+02 3.0 0.4 2 23 43 65 42 65 0.85
2 17 2.8 2.9e+02 3.5 1.6 3 23 105 122 104 122 0.70
3 17 0.014 1.4 10.8 1.2 1 17 128 144 128 145 0.93
4 17 0.015 1.5 10.7 0.4 2 20 151 169 150 171 0.93
5 17 0.51 53 5.8 0.1 3 21 234 252 232 253 0.94
6 17 0.086 8.8 8.3 4.0 1 23 333 356 333 356 0.95
7 17 0.00011 0.011 17.4 4.1 1 23 419 441 419 441 0.98
8 17 1.2e-07 1.2e-05 26.7 3.0 1 23 447 469 447 469 0.98
9 17 0.00024 0.025 16.3 2.1 1 23 475 497 475 497 0.98
10 17 0.0011 0.11 14.3 1.1 1 23 516 538 516 538 0.94
11 17 0.021 2.1 10.2 0.2 1 23 547 570 547 570 0.97
12 17 0.0021 0.22 13.3 3.4 1 23 576 599 576 599 0.96
13 17 0.0057 0.59 12.0 2.0 3 23 609 631 607 631 0.92
14 17 0.00038 0.039 15.7 7.0 1 23 636 658 636 659 0.96
15 17 0.00046 0.047 15.4 1.5 1 23 667 689 667 689 0.99
16 17 4.1e-05 0.0042 18.7 0.7 1 23 695 717 695 717 0.95
17 17 2.2e-05 0.0022 19.6 0.9 3 23 725 746 723 746 0.97

Sequence Information

Coding Sequence
ATGGAATTAGACAGTGAAGAGCAACTAAACTCCCATGTTACAGGGCAACATAAGAGAACTGCGAAATTCGACTTATCCGACAGAAAGATCAAGCAAATTGTAAAATATCAGGCTGGCCAGGAAAttccatgtagattttgtaattTATCCTTTTACTCAAATATTCGAAAAGCAGCTCACGAGAACAAAATGCATTGTGAAGAACTAGTTAAGTGTCCTTCTTGTAACAATCAAATCCCCTTAAAAAGACTGAGAAGTCACAAAATGGCACATAAAATGAAAGAAATATATAAAAGCCTAGTTCTCGAAGTCTGTCCTGTTTGTGGGATCACAACTAAGCGTCTGAAAAAACACATGGTTCGCCACGAGGAACAACGAAAGTACTCTTGTGACTTTTGTGACAAGACTTTTAAATACGACTCGCAGTTAAACGTGCTTCTTTTAGAACTCCAATGTTCCTACTGTAAGGAAGAATTTACCTCCGTGCAAGCCTTACATCAGCATTTAGAAAATTTACGTGCCTTTGCATCTATTTTTTGTACAAGCTGCAAAGAATTTTCTCGATTAGAGGAACCGCTACACCATCACAACTATCAGTACTACTGTAAGATTTGTCGCTTACCTCTTCTTACCTATTTGGATCACAAGTGCTTTCACACAAAATCTTCACAAGGCAAAGCTAGTAAGAGCAAAGTTATTTGTGATAAATgcaaagtgatatttttttccaaaagagtCCTATTAGATCACTTACGAGAGTGTCAGAACCCAAAAATTGTAGTATGCAAATGctgtaaaaagaaatttttaaataaagacgaACTTGAGTTTCATATCAGTTCCATAGGAAATGTAAAAACCGTCGACTTATTAACTTGTTTCCGTTGTGAGTTGTCCTTtgataatatgaatattttaaaagatcacATTGCAAGTTGCGACGTTCACTGCTTTAAACCGAGATCTAATAAAATGAGTAATTCAAAACATAAAGAATACGAATGCAGGTTTTGTCATATAGAGTTTAAGTATAAAAATGATATGACATCACATGAAAAACAAACCCATTCTTCTGATGTAGTGACGTGTTCCATCTGTCAAAAGGAACTGCCGTTTAGAAGACTAGGACCGCATAGTCGATGGCATCGTACTAGAGAGAAATACAAAACAAAGCCAAAAAAGGTGTGTGATATTTGTGGTATTTCCTCGAAATTTATTGATAGGCATATGAAAGTACACAAGGAAGAACGGAGGTATAAGTGTAATGTTtgcaataaaagttttaaacttaGCTCTTGTCTTTCAAATCATAAATTGGTGCATAGCGATGTTGCTAGACACAAATGTAATGTATGTGATAAAGCTTTTAAGAGCAATTTTAACTTGCAAGTGCATATGCGCTCTCACGAGGTAGTAAAACCGTTTTCATGTGTGGTGTGTGATAAAACCTTTACTACGAAGCAATCTAGAGATAACCATTTAAAAACTCACGATCGgaagGAGGAACTATCAAGCAGACTTATTGGAAAGAAGAATCAGGAGACCTATCTTTGTAACGAATGTGGCAAAGAATTTACCAAAAAGAAGTCATGGGGTGCACATAAGACTAGGCACGAAAGACTTAAACACGGAATACGGTTTCCATGTGAAGTGTGCGGCATTATCTTCCTGGACAAGAAAACTGTCGAAAATCACAAAAGAAAAGTTCACCTTCACGATTTTCAATATTGTTGCGAACAATGTGGTCGAGCATTCGTTTGTAAAGGCCAGTTAAACCGCCATGTTAAAATTACTCATGAAGAGCAAGagataactttatttttgtgTGATTTTAACCAGTGTAAAGAGACGTTTACGAATAAGGCAACCTTTCAataCCATCTTCTAAAACACGAAGAAAAAATTTACACCTGTGATTTTTGTCGTAAAACTTTCAAGCACCCATATAGACTTAAAATACACATTAAGAATCACCATGGAAATCGACCGAAAAAACTATATCAGTGTAAATTTTGTGACTTAGAAGTTACAACTAAGTTGAGCTTGAGAGACCATACGAGAACTCACACGGGAGAGAAgccgtttatttgtgaacaatGCGGGCAAAATTTTACTACGAATCAACAGCTTAAAACGCACACCGTAGTTCACTCAAAAGAAAAACCTTTTGGGTGTAAAACTTGTGATAAAAAGTTTACACAAAGGGGGACCTTAAGTGCTCATATTAAAATTTctcatttacaaaattaa
Protein Sequence
MELDSEEQLNSHVTGQHKRTAKFDLSDRKIKQIVKYQAGQEIPCRFCNLSFYSNIRKAAHENKMHCEELVKCPSCNNQIPLKRLRSHKMAHKMKEIYKSLVLEVCPVCGITTKRLKKHMVRHEEQRKYSCDFCDKTFKYDSQLNVLLLELQCSYCKEEFTSVQALHQHLENLRAFASIFCTSCKEFSRLEEPLHHHNYQYYCKICRLPLLTYLDHKCFHTKSSQGKASKSKVICDKCKVIFFSKRVLLDHLRECQNPKIVVCKCCKKKFLNKDELEFHISSIGNVKTVDLLTCFRCELSFDNMNILKDHIASCDVHCFKPRSNKMSNSKHKEYECRFCHIEFKYKNDMTSHEKQTHSSDVVTCSICQKELPFRRLGPHSRWHRTREKYKTKPKKVCDICGISSKFIDRHMKVHKEERRYKCNVCNKSFKLSSCLSNHKLVHSDVARHKCNVCDKAFKSNFNLQVHMRSHEVVKPFSCVVCDKTFTTKQSRDNHLKTHDRKEELSSRLIGKKNQETYLCNECGKEFTKKKSWGAHKTRHERLKHGIRFPCEVCGIIFLDKKTVENHKRKVHLHDFQYCCEQCGRAFVCKGQLNRHVKITHEEQEITLFLCDFNQCKETFTNKATFQYHLLKHEEKIYTCDFCRKTFKHPYRLKIHIKNHHGNRPKKLYQCKFCDLEVTTKLSLRDHTRTHTGEKPFICEQCGQNFTTNQQLKTHTVVHSKEKPFGCKTCDKKFTQRGTLSAHIKISHLQN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-