Basic Information

Gene Symbol
-
Assembly
GCA_935413225.1
Location
CAKXYS010000125.1:133813-167938[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.6 62 5.6 1.0 6 21 12 27 7 28 0.88
2 14 0.69 71 5.4 0.3 1 12 149 160 149 169 0.87
3 14 0.11 11 8.0 5.3 1 20 320 339 320 341 0.93
4 14 0.006 0.61 11.9 0.3 1 23 365 387 365 387 0.99
5 14 0.00051 0.053 15.3 2.5 1 23 406 428 406 428 0.97
6 14 0.048 4.9 9.1 1.0 1 23 447 468 447 468 0.74
7 14 0.008 0.82 11.5 0.1 2 23 475 496 474 496 0.96
8 14 0.0023 0.24 13.2 0.2 1 23 502 524 502 524 0.95
9 14 0.00017 0.018 16.8 1.6 1 23 530 552 530 552 0.98
10 14 2e-05 0.0021 19.7 3.7 1 23 558 580 558 580 0.98
11 14 9.7e-05 0.0099 17.6 9.6 1 23 586 608 586 608 0.99
12 14 0.00017 0.018 16.8 0.9 1 23 614 636 614 636 0.98
13 14 2.4e-05 0.0025 19.4 0.1 1 23 640 662 640 662 0.98
14 14 0.00043 0.044 15.5 0.1 1 23 670 693 670 693 0.95

Sequence Information

Coding Sequence
ATGGCGCCGTTATCTTTAGCGTGTCCTTTATGCTGTAACGAAACCTTTTCTTCACACATTTCCCTAAAATATCATCTTTTAAGTATGATAGATAACTTATTATGTCCTTCATGTAACGAAAGATGCGACGATTTAATGGATATGGCAGATCATTTGGGTAGAGAGTGCAAGAATTTGAAGAAATCGACTGGGGAGGAACAGTTAGAGAAACCTATTGTTTCCCTGGAAACTAAAACTGAAAAAAGTTTAGAAGAGACTAAAGTTCCTGGAACTAATCATCTCGAACCTCAAATAAAACTTGAAGTTCTAGATAATTCAACTGAAAATACTAAAACAGGCAGTAAAATTATAGATATTGATGAAAAAGGGAATGTAAATGAAGCTCTTAGtgaaaaaataagtgaagataaCCATGAAGAAACAGAGATGATCGAGGAGATGATGTATACTTGCCAGATGTGCGATGTTACCTTCAACTCTGTGCAAGAACATCTAGCAAAGTATCATGAAGGGGAGGAAGTCTTATTGGAAACAGAACATGATGAAAATGCCGACAGTCAAGGAGAAGAAGTATCCGTCTTAGAGTACCGTGTGGGAACGATTGACGACGATGCCGATGATAACGACGATCCATTTGGGGATGAAGGAAGTATCGTGGGGAATTCGGAAAGCGTTGCCAACGCAACAAAGAGaacagGTTCAAGCATAGGCCAAACGATTTCTGAACAAGAAATGGTTGATAAGACCGGAATGGGCTATACAAGAAAAGTGGTAAAAGTCGGTACTGATTGGATAACCGATAACCAAGAATCGGAATCAAATGCGAAGAATTGGCCGGAAGACAATGAAGAAACAGAACCTGatacaacaaaatatatagTTGAAGAAGGAAAAGTACGGAAATTATCGGCCGAAGAGGCGGACGCAATTACCGACAAGTCGTCGATAATCGAGGTGCACAGGTGTCCGAATTGTGAATTGCAGTTCCCAAATATGTCCCATTTTAAGAAACATAGTTGTAAGAACGCCAAACCTATGACCAATAAAAGAGCAAAGAGAACAGAACTACTCAAGcttaaaGAAGAGTTAAGATACCAGTGCACCTTTTGTTTGGCTATATATTCAACTTTAATTGGTTTGAACGATCATATGAAGTCTCATTTGATTGAGGATGAATCAGGTATGGTTCAAAGGAAAACAATAACAATGACTCTTCATATCTGTGACATCTGTAATACGAAATTTCCGACCTATAAACAGTTGAGGCTGCACAGTAGAATGCACGATCCAGTCAAAACCAAAGAAGTCGATCCACCAGTGAACTCGGAGAGCGAGTCATTTCAGTGTCCCATATGCGAGAAAACTTATGACAAGAAATACGAAGACGTCCATATGAAATCTCACGAGGAACAGGAGCACACTGTTTGCCTCGTTTGTAACAGAAAGTTTGATGCCATAGAGAATTTAGAAATGCATATGAAAGCTCACTCCAATACCAAAAAGTTTGCATGTTCCTATTGTAAAAAGCCGTTCAATAGCTATGCAGTTTTAGAAGATCATGTACTAAATCATTGTCAGAAGAGGCAGTATGAATGTCAGTATTGTGGTAGGAGATTCGGTAGACCACACGAAAAGgttaaacACGAGAGAATTCATACTGGAGAAAAGCCGCACGTGTGCCAGCTTTGCGGTAGAGCGTTTAGAGTTAGTTACTGTCTTACTTTGCACATGCGCACTCATACAAATACCAGGCCGTATACTTGTCAGCATTGCGGAAAACGgtttaagTCACACAGTGTATTTAATCATCACATGCAAACCCATTCCGATGAGAGGAACTACAAGTGCTCGTTTTGTCCTAAAGCCTTTAAAACTACGGTGCAATTGGCTGGGCACAAAAATAgTCATACCAAACCTTTCTCGTGTACTGATTGCAACCGACCCTTCGCCTCCCTCTACGCGGTGAGGGCACACATGGAGACGCACAAGAGGGACAACAATCTGAAATTCGACTGCTGGATGTGCGGAGCTAGTTACGCTAGGTCGTTCGCGCTCAGAGATCACATGACTAGTGCGCATGGTAAAGCACCGACAGAAAAAGGAGTGAACGATAACGGCATTGTTGAGTTCGAAAGTCCAATAAACGATGTGGCGGAGCATTTAGAAAATAGTACTGAAGAACGCCAAGGCGATGAAGAAAACCCAATATCAGTTGAAGAAGTGGATTATCATATGGCAgGCACTGATGGCGAAGTCTTAAGTACCCATAAAGACGAAACGACCCAGGGTTATGTAGTACATTTGCAAGAGGTTGAAAATAGTGAACACGAGGAAGGAAGTCAGATGGAAGTGGTTGAAGCCTAG
Protein Sequence
MAPLSLACPLCCNETFSSHISLKYHLLSMIDNLLCPSCNERCDDLMDMADHLGRECKNLKKSTGEEQLEKPIVSLETKTEKSLEETKVPGTNHLEPQIKLEVLDNSTENTKTGSKIIDIDEKGNVNEALSEKISEDNHEETEMIEEMMYTCQMCDVTFNSVQEHLAKYHEGEEVLLETEHDENADSQGEEVSVLEYRVGTIDDDADDNDDPFGDEGSIVGNSESVANATKRTGSSIGQTISEQEMVDKTGMGYTRKVVKVGTDWITDNQESESNAKNWPEDNEETEPDTTKYIVEEGKVRKLSAEEADAITDKSSIIEVHRCPNCELQFPNMSHFKKHSCKNAKPMTNKRAKRTELLKLKEELRYQCTFCLAIYSTLIGLNDHMKSHLIEDESGMVQRKTITMTLHICDICNTKFPTYKQLRLHSRMHDPVKTKEVDPPVNSESESFQCPICEKTYDKKYEDVHMKSHEEQEHTVCLVCNRKFDAIENLEMHMKAHSNTKKFACSYCKKPFNSYAVLEDHVLNHCQKRQYECQYCGRRFGRPHEKVKHERIHTGEKPHVCQLCGRAFRVSYCLTLHMRTHTNTRPYTCQHCGKRFKSHSVFNHHMQTHSDERNYKCSFCPKAFKTTVQLAGHKNSHTKPFSCTDCNRPFASLYAVRAHMETHKRDNNLKFDCWMCGASYARSFALRDHMTSAHGKAPTEKGVNDNGIVEFESPINDVAEHLENSTEERQGDEENPISVEEVDYHMAGTDGEVLSTHKDETTQGYVVHLQEVENSEHEEGSQMEVVEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-