Basic Information

Insect: Polydrusus cervinus
Gene Symbol: zfh1
Assembly: GCA_935413225.1
Location: CAKXYS010001080.1:59422-64086[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 24 0.44 45 6.1 2.2 1 23 4 27 4 27 0.95

2 24 6.1e-06 0.00063 21.3 0.4 1 23 72 95 72 95 0.93

3 24 0.063 6.5 8.7 0.1 2 23 105 127 104 127 0.94

4 24 0.34 35 6.4 0.5 1 23 146 169 146 169 0.93

5 24 0.49 51 5.9 0.2 1 23 187 210 187 210 0.93

6 24 0.0074 0.76 11.6 2.0 1 23 228 251 228 251 0.94

7 24 6.6e-05 0.0068 18.1 0.6 2 23 440 462 439 462 0.94

8 24 0.025 2.6 10.0 0.6 2 23 471 493 470 493 0.96

9 24 5 5.1e+02 2.7 0.1 2 11 501 510 500 519 0.87

10 24 0.16 17 7.4 3.0 3 23 529 550 528 550 0.93

11 24 0.35 36 6.4 0.5 1 23 558 583 558 583 0.94

12 24 0.0023 0.24 13.2 2.5 2 23 591 612 591 612 0.97

13 24 0.00039 0.04 15.7 1.7 1 23 621 643 621 643 0.96

14 24 0.031 3.1 9.7 1.6 1 23 649 671 649 671 0.92

15 24 0.0003 0.03 16.0 2.2 1 23 677 700 677 700 0.97

16 24 6.1e-05 0.0063 18.2 2.1 2 23 726 748 725 748 0.94

17 24 8.8e-06 0.00091 20.8 4.1 1 23 757 780 757 780 0.97

18 24 0.0011 0.11 14.2 0.6 1 23 787 810 787 810 0.94

19 24 0.0098 1 11.3 0.8 2 23 817 839 816 839 0.95

20 24 0.0066 0.67 11.8 0.1 2 22 847 869 846 871 0.87

21 24 5.8e-06 0.0006 21.4 2.7 2 23 879 900 878 900 0.96

22 24 1.6e-05 0.0016 20.1 0.2 1 23 907 929 907 929 0.98

23 24 0.0037 0.38 12.6 1.1 1 23 935 957 935 957 0.95

24 24 0.00019 0.02 16.6 1.5 3 23 965 986 963 986 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	24	0.44	45	6.1	2.2	1	23	4	27	4	27	0.95
2	24	6.1e-06	0.00063	21.3	0.4	1	23	72	95	72	95	0.93
3	24	0.063	6.5	8.7	0.1	2	23	105	127	104	127	0.94
4	24	0.34	35	6.4	0.5	1	23	146	169	146	169	0.93
5	24	0.49	51	5.9	0.2	1	23	187	210	187	210	0.93
6	24	0.0074	0.76	11.6	2.0	1	23	228	251	228	251	0.94
7	24	6.6e-05	0.0068	18.1	0.6	2	23	440	462	439	462	0.94
8	24	0.025	2.6	10.0	0.6	2	23	471	493	470	493	0.96
9	24	5	5.1e+02	2.7	0.1	2	11	501	510	500	519	0.87
10	24	0.16	17	7.4	3.0	3	23	529	550	528	550	0.93
11	24	0.35	36	6.4	0.5	1	23	558	583	558	583	0.94
12	24	0.0023	0.24	13.2	2.5	2	23	591	612	591	612	0.97
13	24	0.00039	0.04	15.7	1.7	1	23	621	643	621	643	0.96
14	24	0.031	3.1	9.7	1.6	1	23	649	671	649	671	0.92
15	24	0.0003	0.03	16.0	2.2	1	23	677	700	677	700	0.97
16	24	6.1e-05	0.0063	18.2	2.1	2	23	726	748	725	748	0.94
17	24	8.8e-06	0.00091	20.8	4.1	1	23	757	780	757	780	0.97
18	24	0.0011	0.11	14.2	0.6	1	23	787	810	787	810	0.94
19	24	0.0098	1	11.3	0.8	2	23	817	839	816	839	0.95
20	24	0.0066	0.67	11.8	0.1	2	22	847	869	846	871	0.87
21	24	5.8e-06	0.0006	21.4	2.7	2	23	879	900	878	900	0.96
22	24	1.6e-05	0.0016	20.1	0.2	1	23	907	929	907	929	0.98
23	24	0.0037	0.38	12.6	1.1	1	23	935	957	935	957	0.95
24	24	0.00019	0.02	16.6	1.5	3	23	965	986	963	986	0.95

Sequence Information

Coding Sequence: atgttacggTATAAATGCGACAAATGCTGTAGCAGCTTTCGTCGTAAGGGTCTGGTTGTTCAACATCTTGCCATTAAACACAACTATATTTCTGATAATAGCCAGAAGAAAAGTAAtgaacattataaaaaagttactctgaatttaaaaaacaatcatAACCTGATAAAAGACACCAATGTTTCCAGGACAAGCAAGGGAGTTGTCGTTAATTTTTCGTGCCCAAAATGTggaaaagatttcaaaaatatatctagCTTGAATAAACATGTTGCCAACGATCATGTGACCGTCGACCTAAACGAGTATGTTTCTTGCCTGGAATGCGGagcaatttttaatgaaaactacAGTCTTGATGAACATCTCACTAAAATTCATGGGTTTATTCACGCTCGACGGTTTAACCAACCAAAACCAATCTACGGGAAAAAGTTTCGTTGTCTAGAATGTAAACTTATATTTCTTACTAACCGTAGCCTTTCTAACCACGTAAGTTTAGTTCATAGACAAATGGATGAAGCAAGTTCTTCTGTTGCAAGTAAGGACAACACTACTTTCGATTGCTCGTTTTGCGGAGCACTTTTCACTAATAGTATTATCCTGAACGACCACGTTAGGGCCTTCCACAAAAGCATGGATGCAGGAAGTATTTCTGAAACCACAAAAAAGAGCGAGATTTTCTCTTGCTATAAATGCGAGtacatttttaatcataaaaacgaCCTTAGCGACCACTTACAAGATATTCATGGAGATGTTAATGCTGCAAATATTCCTGTACATGCAAATGATGTTTCGGAAGTTTTTAACGAAGAAAATTATAATAGTGGTAGCGACTATCCCAACGATGAAGCAAGTGTTTTTGAAAACACAATCCGTATTACGGAAATTGTTGCCGGTGTAGATTGCGAAAAACTGTTTAACGAAAATAGTACCATCAGCGATGATATCAGAATGGATCATGTAGATAAAGCAAGTTGTTTCACAGACACAAAttgtattatgaaaaatatttcttctttagATTACCAAAATATCTTTAACGAAAGAATAATCGATATTACCGATCACGTTAAACATACGAATAAATCTATAGAAGTTGCACGAATTCCTGACAATATTGAAGTCGCTAACGTTTGTTCCAACCATGTGGAAAAAACAAGTGTTATTGAAGATTCAAAtagaataaaaaagaaatttccttGTCCCTGTGATCATtgcgataataaaaaaaatagtcttgACGTCCATGTTAAGACTAATAATTTACGTATAGGAGATGTATCTATTTTAGATACAGATAAGGGCACTTTAAAATGCCCGGACTGTGAAAAAGTATTTGGTTCTAAGAACAAATATTTCAGACATATGGAATACGTtcacaataatttaaaagacGAAGAAATTACTTGTAAAGAATGTGATCAAATATTTATGACATACTTTACTTTTGATGAACACATTAACAAAATGCATAaagaaatgaaaaatgttaatcAATGTCCTGTTTGTGGGATGAACTACAAAGGTTCGATCGAAGACCACAATCACTTGTTACACCGGAAACCTTATAGTGTATTTTGTACGAGATGCTCTAAAGGATGTTATTCTCTGAAAGGGTTGAAAAGACACATGGTAAATGACCATAAAATGCGTGAGAACATCCGTTTTCCTTGCACCGAGAATAAGTGCGTCAAATTATTTACTAATAGAAACGCATTTTTGTATCATTTAGGTACAGTACATATAAAGGCAAAATTTAAGGCTTCTTGTGAAGAATGTGGAAAGGTACTGACGCATCCCAACAAATTTATAAACCATGTAAGACATCACAAAAAATACTATCGCCCGGGAACGCATCCATGTCATATCTgtgacaaaattttaagttcAAAAACCAGTTTACAAGATCACTTAGTCTCTCACAGCGGTCAAAGACCGTATATCTGTGAGAAGTGCGGAAAAGGATTTATTTGTTTAAAGCATCTGAAGGTGCACGGGGTGGTGCATACGAAAGAGAAGCCATATCCGTGTAAATATTGCGATAAAAGATATACTCAACGAGCTCCAGTTTCTCGGCATATACGCCTTTGTCATCCTGAGATGcgatgttctaaaaatatatcaactgAAAAAAAAGCGAACAAACAAGAATATGACATAGATGATTGTCCCTGTCCCCAGTGCGAAAAAGTGTTTTCCAAGAAGCGATACCTCACCAATCATCTGAACTACGTTCATAAACTAAAGCcacagaataaaatattttgttgcacGGAGTGCGACAAGAGCTTCACTAGaaactttactttaaaagaTCATATTAATAAAGTTCACAGGGGCCTTGTGGAATTCCATCAATGTGACATATGTGGAGAAAAATTCAAAGGaaaacaaaacattataaaccATAAAAACGcagtacatttaaaaaaattcaatattcacTGTGAGTTTTGTGGTAAAGGTTTTCTTTATGAGAGCGGTTTAAACCAACATATTAAAAGTACCCATGAAGAAAGAGTCAACATTATTCCATGCCCTGAAGACGGATGCGTAAAAACGTTTAAGACAAAAGAAGCCTTGAAATATCATAAAGACGCTGCACACGCCAAAGTAAAACTTAAGTTAGTTTGTGAACAATGTGGAAAAACATTCACGCATCCTTTCCTGTACACAAAACATATGAGATTCCACAGAAAGGGTCCGACTATGTATCCGTGTAGTGTCTGTGATAAAGTGGTGACTAGTTTAGGAAGTTTTAAGGATCACATGCGCAGTCACACCGGGGAAAGAccgtttatttgtgaacaatGCGGACAAGGATTTCATGCCAAGAAACATCTGAGGGCGCATGTGGTGGTGCATACCAAGGAAAGACCTTTTGGTTGTAAAATATGCGATAAAAGGTTTTCACAAAGGGGTACCTTGACGTTGCATAATCAAAAAAGCCATCCAGAGTTAAATGATAAACGCTaa
Protein Sequence: MLRYKCDKCCSSFRRKGLVVQHLAIKHNYISDNSQKKSNEHYKKVTLNLKNNHNLIKDTNVSRTSKGVVVNFSCPKCGKDFKNISSLNKHVANDHVTVDLNEYVSCLECGAIFNENYSLDEHLTKIHGFIHARRFNQPKPIYGKKFRCLECKLIFLTNRSLSNHVSLVHRQMDEASSSVASKDNTTFDCSFCGALFTNSIILNDHVRAFHKSMDAGSISETTKKSEIFSCYKCEYIFNHKNDLSDHLQDIHGDVNAANIPVHANDVSEVFNEENYNSGSDYPNDEASVFENTIRITEIVAGVDCEKLFNENSTISDDIRMDHVDKASCFTDTNCIMKNISSLDYQNIFNERIIDITDHVKHTNKSIEVARIPDNIEVANVCSNHVEKTSVIEDSNRIKKKFPCPCDHCDNKKNSLDVHVKTNNLRIGDVSILDTDKGTLKCPDCEKVFGSKNKYFRHMEYVHNNLKDEEITCKECDQIFMTYFTFDEHINKMHKEMKNVNQCPVCGMNYKGSIEDHNHLLHRKPYSVFCTRCSKGCYSLKGLKRHMVNDHKMRENIRFPCTENKCVKLFTNRNAFLYHLGTVHIKAKFKASCEECGKVLTHPNKFINHVRHHKKYYRPGTHPCHICDKILSSKTSLQDHLVSHSGQRPYICEKCGKGFICLKHLKVHGVVHTKEKPYPCKYCDKRYTQRAPVSRHIRLCHPEMRCSKNISTEKKANKQEYDIDDCPCPQCEKVFSKKRYLTNHLNYVHKLKPQNKIFCCTECDKSFTRNFTLKDHINKVHRGLVEFHQCDICGEKFKGKQNIINHKNAVHLKKFNIHCEFCGKGFLYESGLNQHIKSTHEERVNIIPCPEDGCVKTFKTKEALKYHKDAAHAKVKLKLVCEQCGKTFTHPFLYTKHMRFHRKGPTMYPCSVCDKVVTSLGSFKDHMRSHTGERPFICEQCGQGFHAKKHLRAHVVVHTKERPFGCKICDKRFSQRGTLTLHNQKSHPELNDKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -