Basic Information

Insect: Pollenia labialis
Gene Symbol: wek
Assembly: GCA_949318255.1
Location: OX439141.1:29650642-29652859[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0038 0.53 12.3 2.8 1 23 354 377 354 377 0.94

2 8 1.3e-06 0.00017 23.3 1.6 2 23 393 414 393 414 0.97

3 8 0.00064 0.089 14.8 0.7 3 23 425 446 424 447 0.94

4 8 0.00031 0.043 15.8 0.2 1 23 452 474 452 474 0.97

5 8 5.8e-06 0.0008 21.2 3.5 1 23 480 502 480 502 0.98

6 8 0.00095 0.13 14.2 0.5 1 23 507 529 507 529 0.98

7 8 0.00011 0.015 17.2 0.9 1 23 535 557 535 557 0.97

8 8 0.0022 0.3 13.1 4.1 1 23 563 586 563 586 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0038	0.53	12.3	2.8	1	23	354	377	354	377	0.94
2	8	1.3e-06	0.00017	23.3	1.6	2	23	393	414	393	414	0.97
3	8	0.00064	0.089	14.8	0.7	3	23	425	446	424	447	0.94
4	8	0.00031	0.043	15.8	0.2	1	23	452	474	452	474	0.97
5	8	5.8e-06	0.0008	21.2	3.5	1	23	480	502	480	502	0.98
6	8	0.00095	0.13	14.2	0.5	1	23	507	529	507	529	0.98
7	8	0.00011	0.015	17.2	0.9	1	23	535	557	535	557	0.97
8	8	0.0022	0.3	13.1	4.1	1	23	563	586	563	586	0.97

Sequence Information

Coding Sequence: atgcgtgacaaacatttaacaaaaacaaaccacACAAATGATAATGACATACACACCCAGTGGTTACGCTGGTGTCGCTTGTGCGCCAAACGGGAACTGGATGAGCAAGAgagtttgtcaatttttgtacAATACGAATCTGGAAAACTGGATACTGATTTGGCTACATCTGTAGGAAAATATTTCTGGGTTAATATTAAAGCAGACGATGCGATTTCACAGTGCTTGTGCTTGAACTGTAAACAACTTGTCGAGGAGTTAGTTATATTTACCGAACGTGTTAACAAAGtacaaactttattttgtttattgcaaaatataaaaccaGAAACAGACGAACAGGCAGACAAATTACGTGCTCAATGTGGGCTTGTTGATATGAGCTGGCAACATATAATAAAACCCGAGTTCTTCGAATCACCAAAACCATTATCAATTGACCAAGAAATACAAACGGAAGAGATGACTTGCCCTCAAGATGAAAAACAACATACAGAATcacaaactttaaaagaaactgaggaaataattaatattttacaaaaacctgACAATAATGAGGGTTATGAATGCCAAACAGAGAACAACGTGCTCGTTGAGTATGTTGGACAGGAAGAAAACGAACTGGAATTTGTTGATAATGATTATATGGTGCCCTCCAATAGTATGAATATCGGTgttatcaaacaaaatatacagGAGCCCACTGAAGACGAAGAGGTTGTGCAGGACAGTGATCTTTTTAAAgagcttaaatataaaatagatGACGAGGAGGATGAAGAAATACAcccaaaaaaattcaagataacTTCTGAAGGGGAGGAAGTAGAGGTAGAGTATCACGATGCACACACTTTGGAGGAAGAGGGCGATGAAGTTATTGAACAATCTATTGAGATTCTAGAGGAGATGGAGGTGCAAGAAGGTGAGGAAGACTATGCTAATATAAGTGAtaatcaaaatgaaacaagaattgAGGCCTTTGCTTTGATGAAGGGCAAACGGGGGCGACCTATTGGCTCAAAGAATTCACCAACCGATGGCTCCACCGTTCATTTCGAGTGCATGGAGTGTAAACGTAGATATAAAAACCCCAAAGTCTTCCGTAAACACATGAGCTTTTCACATAATATAGTCGTAGACAATTTACCGGATTTCAAAGCGAAATCAAATACCTGTAAAATTTGTGGTAAAGTATATGTAACGCAAGGTAGCTTAAAATTACACATGAGACACCACTTGCCAGACgaggaaaaatataatatactcTGTCCATATTGCAATCGCAAATTTTCCCAATTGGGAGCCATGAGGCAGCATGTTAATGGTATACATCATCAAATGAAACCTTTTATATGTGATCAATGCGGTCGAGCTTGTAAAACAATGGCAGCTTTAACCGAGCACCTACTGGTACACAGCAATGAGTGTCCATTTGAATGTAAAGTGTGCCATAagggatttaaaaataaatctagacTTAAGACCCATATGGACATACATGACAAATGTGTATATAAATGCCCAGACTGTAGCCTTGAGTTGAATACAAAAAGAACCCTACTGCAACATCGTTTAGTGCATAGCGATGAAAAACGTTTTAAGTGTCAATTTTGTGAGGCGGCCTTTAAAAGATCAAAGGCTTTAAAAAATCACTTGATCTTACATACAGGTCTGAGACCCTACAAATGTAATTTCTGCAACAAAGCTTTTTCAAACGGCTCAAATTGTAGGGCTCACAAGAAACGCGCCCACCCCACAGAATTGGCTGAAGACGAGGCTAATGGCAAAGTATCTGAAATAACGCCTATACCAAAATTAGAAGAATTAAAGTCGgccaaggGTGTCTTAGTGCAACCACGTAAAGTTAAACGTAATACTGGTGGTTTACCCAATAAATTgcgtaaacttttaaaaacgtcTAAAAAACAAGCGCAAAACAATTCCACTGAGTATGAAGATGCTGCGGAAAACGGTGAATCCTTTTCCGATTTTCATTACGAGATTTGTAAATCTGAAATAGATGAAACGGAATCAATTGTTGATAATCCTAGTGAGGAATGTGAGGAAACTGTTATATATGAAATTATTGatgaaatataa
Protein Sequence: MRDKHLTKTNHTNDNDIHTQWLRWCRLCAKRELDEQESLSIFVQYESGKLDTDLATSVGKYFWVNIKADDAISQCLCLNCKQLVEELVIFTERVNKVQTLFCLLQNIKPETDEQADKLRAQCGLVDMSWQHIIKPEFFESPKPLSIDQEIQTEEMTCPQDEKQHTESQTLKETEEIINILQKPDNNEGYECQTENNVLVEYVGQEENELEFVDNDYMVPSNSMNIGVIKQNIQEPTEDEEVVQDSDLFKELKYKIDDEEDEEIHPKKFKITSEGEEVEVEYHDAHTLEEEGDEVIEQSIEILEEMEVQEGEEDYANISDNQNETRIEAFALMKGKRGRPIGSKNSPTDGSTVHFECMECKRRYKNPKVFRKHMSFSHNIVVDNLPDFKAKSNTCKICGKVYVTQGSLKLHMRHHLPDEEKYNILCPYCNRKFSQLGAMRQHVNGIHHQMKPFICDQCGRACKTMAALTEHLLVHSNECPFECKVCHKGFKNKSRLKTHMDIHDKCVYKCPDCSLELNTKRTLLQHRLVHSDEKRFKCQFCEAAFKRSKALKNHLILHTGLRPYKCNFCNKAFSNGSNCRAHKKRAHPTELAEDEANGKVSEITPIPKLEELKSAKGVLVQPRKVKRNTGGLPNKLRKLLKTSKKQAQNNSTEYEDAAENGESFSDFHYEICKSEIDETESIVDNPSEECEETVIYEIIDEI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01237072; iTF_01236053;
90% Identity: iTF_01237072;
80% Identity: -