Basic Information

Insect: Pollenia griseotomentosa
Gene Symbol: topi_1
Assembly: GCA_963931875.1
Location: OZ007563.1:10062250-10088329[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 0.35 58 6.2 3.5 1 23 241 264 241 264 0.94

2 22 0.0051 0.84 12.0 0.9 2 23 324 345 323 345 0.96

3 22 0.043 7.1 9.1 4.2 1 23 461 484 461 484 0.93

4 22 0.024 3.9 9.9 2.7 2 23 545 566 544 566 0.97

5 22 0.0024 0.4 13.0 1.5 1 23 643 666 643 666 0.96

6 22 3.8 6.2e+02 2.9 0.8 2 22 674 694 673 694 0.92

7 22 0.0034 0.56 12.5 0.4 2 23 772 793 771 793 0.97

8 22 0.022 3.7 10.0 1.3 1 23 874 897 874 897 0.95

9 22 0.0009 0.15 14.3 1.9 1 21 904 924 904 925 0.95

10 22 1.7 2.7e+02 4.1 0.1 2 23 937 959 936 959 0.90

11 22 0.05 8.3 8.8 1.1 3 23 1020 1040 1019 1040 0.94

12 22 0.065 11 8.5 0.1 2 19 1067 1084 1066 1087 0.93

13 22 8.7e-05 0.014 17.5 5.1 1 23 1137 1160 1137 1160 0.97

14 22 0.033 5.5 9.4 0.6 1 23 1197 1220 1197 1220 0.96

15 22 2.6e-06 0.00042 22.3 1.2 1 23 1263 1286 1263 1286 0.97

16 22 0.56 92 5.6 1.7 1 20 1292 1311 1292 1311 0.96

17 22 0.05 8.2 8.9 0.2 5 23 1313 1331 1312 1331 0.94

18 22 0.00064 0.11 14.8 2.0 1 23 1337 1360 1337 1360 0.96

19 22 8.1e-06 0.0013 20.8 0.8 2 23 1386 1407 1386 1407 0.98

20 22 0.0002 0.033 16.4 1.8 1 23 1413 1435 1413 1435 0.99

21 22 0.0014 0.24 13.7 5.3 1 23 1441 1463 1441 1463 0.99

22 22 0.00016 0.027 16.7 5.1 1 23 1469 1491 1469 1491 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	0.35	58	6.2	3.5	1	23	241	264	241	264	0.94
2	22	0.0051	0.84	12.0	0.9	2	23	324	345	323	345	0.96
3	22	0.043	7.1	9.1	4.2	1	23	461	484	461	484	0.93
4	22	0.024	3.9	9.9	2.7	2	23	545	566	544	566	0.97
5	22	0.0024	0.4	13.0	1.5	1	23	643	666	643	666	0.96
6	22	3.8	6.2e+02	2.9	0.8	2	22	674	694	673	694	0.92
7	22	0.0034	0.56	12.5	0.4	2	23	772	793	771	793	0.97
8	22	0.022	3.7	10.0	1.3	1	23	874	897	874	897	0.95
9	22	0.0009	0.15	14.3	1.9	1	21	904	924	904	925	0.95
10	22	1.7	2.7e+02	4.1	0.1	2	23	937	959	936	959	0.90
11	22	0.05	8.3	8.8	1.1	3	23	1020	1040	1019	1040	0.94
12	22	0.065	11	8.5	0.1	2	19	1067	1084	1066	1087	0.93
13	22	8.7e-05	0.014	17.5	5.1	1	23	1137	1160	1137	1160	0.97
14	22	0.033	5.5	9.4	0.6	1	23	1197	1220	1197	1220	0.96
15	22	2.6e-06	0.00042	22.3	1.2	1	23	1263	1286	1263	1286	0.97
16	22	0.56	92	5.6	1.7	1	20	1292	1311	1292	1311	0.96
17	22	0.05	8.2	8.9	0.2	5	23	1313	1331	1312	1331	0.94
18	22	0.00064	0.11	14.8	2.0	1	23	1337	1360	1337	1360	0.96
19	22	8.1e-06	0.0013	20.8	0.8	2	23	1386	1407	1386	1407	0.98
20	22	0.0002	0.033	16.4	1.8	1	23	1413	1435	1413	1435	0.99
21	22	0.0014	0.24	13.7	5.3	1	23	1441	1463	1441	1463	0.99
22	22	0.00016	0.027	16.7	5.1	1	23	1469	1491	1469	1491	0.98

Sequence Information

Coding Sequence: atggacacgagcattaaaaatatatgttttataaaTGGAGTTCAGTATAAATGTCGAACATGCTTTGATCCGGGAAGTGAAGTATTCTCACTTGCAGAAGCTTGCAAAAGCACACAGACCTGGCGTGATTTGTTAAATGAAGTTGGTCAATTGAAGACAAACGAAAACGAGTTACTTCCAAAGACTATTTGCTGCAAATGCTTAACTACACTTATTAGTTACTACGATTTTATACTTCAGATTCAAAATGTGAATAAGAAATATTTCGAGTTACTTGCAAAAGATAATGTTGAACTACAGAGTGGAGCCGACAGTTTTACAGATTCCTTGGCAGGATCTGCTACTGAGTTGCCAATGCAACAGGATGTGACGGAATTAAAATTTGAAGATGAGATGGTTGTCCCATATGATATTGTTTTAAGTAATAGCAGTGAAATGCAACGAGTTCATGGATATAATCTGGAAAATAAAGATGATCATGATCCTTTCAGTGAATACATCAAATTATCTGCAGAGGAGCTGGAAGAAAACAAACGtGAACAAATAGATTGGGAAAAATATATAAGTGCTCAAATCGAAAAAGTCAACCATGGCAACCCATCTTGTAGAAAGGCATACtgctcCTCATCATCCAGTGAAAGTGACGACGAACTGCCTACTGCCAGccaATGGATCCCCGTTAATATGCCgaaatataaaatagaaaaagtgggtaATCGTTTTCTTTGTCCGGTATGTATGAAAACatttactttaaaaagaaattgtcGTCGCCACATCTTTACGATACATGCCAAACAGAATACATTTGCTTGTGCATTTTGTGGACATCATTCTACCTGTATGGAATATTTAAGTACGCACCTTAGCCGCACGCATCCTGGTCAATCGTTACATACGAATGCTAACAAGTTAGCTTTGTTATTTGGAGACCGTTTGTACAGCAAACCTGTCGTTTGGCGTTTTGTGAAATGTATGTTGTGTGACACAATATTTTCAACGACAAAAAAACTGCGTCAACATTTAGCAAATCACAGTGATATTAACACCCTTCATAGTTTGGAATTGAGTAGTAGCATTGTCGAGCATTGGTTTCCAAAcgttattgatttaaatcatgtCAAGGAAATAATTTGTAAAGATATTCTGGAGAAAGATTGGTTTAAATACTACGTAGTTTTAAACGAATATTCTTACGAAGTGTCTGTTAGTGATACAGAAGTAGAAGACTTAGAAGATGAATCTGTAGAGCGTGCGAGCAAATATAATTGCGAAATctccTCATCTTCCAGTGAAAGTGACGGTGAACTGCCCACTACCAGccaaTCGATCGTTAATAAACCTCAAGATgaatatgaaatcaaaaaagttGGTAATGGTTTTCTTTGTCCGGTATGTAAGGAAACATttacttttagaaaaaattgtcGTCGCCACATCACGTCGCAACATAGTAAACACAACAAAACATTTGCTTGTGGATTTTGTGGGCATCATTCTACATGTAAGGAGTTTTTGAGAAGGCATCTTAAGCGCGCGCACCCAGGTGAATCGATGCATACAAATGCTAAGCAGTTAGTTTTGTTATTTGGAGACCGTTTATACAGCGTGCCTACCGCTTGGCGCCTTGTGAAATGTATGTTGTGTCACGCAATATTTTCATCGACAAAAAAACTGCGTCAACATATATCAAAACACAGCGATCCATTAACCCTTCATAGTTTGGAAATAAAGAGTAGCATTGTCAAGCATTGGTTTCCTAATATGATTGATATAATTCaagtcaagaaaaaaatttgtgcagATATTCGTGAGAAAGATTGGTTTAAATACTACATAGTATTAAATGAATACTCGTACGAAGTGTCTATTAGTGATACAGAGGTAGAAGACTTGGAAGATAAAACTGTAGAGCGTGCGAGCAAATACAATTGTGAACTGTGTAATGAAAAGTTTTCTTACAAATATCAAGTTTTTTCCCATTTAAAAGAAGATCATAACGAAAACGACATTCTAATAAGCTGCAGCCGATGCAAATTGGAATTTATATCAATCAAAATGTATGAACATCACAAACAAACTTATTGCGAAAATAAATACAAAGACTTGTCCTGTACACATTGCCCAGGAAAATTTATTTGGCCTGAAAATATGAATAATCATCATTGTCCCCCAAAAACAACGGTATATGATGCCACTAAAGGTCATGCAATATTCACAAGTGTTCCTGAGGTtggaaaaaataatatgtatcaAAAAGATGATTTAGAAACTAATGACGATACCAGAATTGTACTACCAAAAAATGTTATACGCTGTGGTCTTTGTGAGTTAAGTTTTGAAAAGTTGCAATATTTACGGCAACACATGTCTATGCATGCTGACGGTAAAAGTGGCATTGACTTTGAAAGCTGTATTTATGTAAAACAATTAAGACGTTCATCAGTAATTAATTACGCATTTCTGAAGCAGCAGATCAAAACTGCCTTTATTAAACGTCAAATAAGTTGTTTTTACCAAGCCATCGACAAGTTCGGCAATGAGATGGATATTTCAGATTCAGATTCTGATTCTGATAGTAATATAGAGGATAGTGACGGTGAAAATGTTCAGAAAGCTTATGCATGCGATGTTTGCAAAGATatgtttaaaaaacgaaaacttcTACTAAAACATCAACAAGAACGTCACAATGCCGAAACATTGCCCTTTACTTGCAAGGACTGCCAAAAACAGTTTGTAAGTATTCATTTGTTGCAACAACATTTAAAGAAAGAATGCTGGAACGAACACCGACGTATAGCACAACCATGTGATATTTGTAATATACGTTTTATATGGCCAAATAATATGTTCGTACACAAGGAAATTCAGCATTATAAAATGGAACAAAATTCTACTGGATTTTCTAAGAACTTTAAATATACCCTACGAGACAAAAAAGAACTTGATCGGCCTAACAATGACAACTCAGCAACAGCTGAAAGTGCTACATCTTTCTACCCTACAACTGCAATACTTATAAAATCTTCTTCTGCTGATATACAACTTCGTTATTGTTTTCTGTGCCCAAAAACATTCTTTGGCATTGAACATCTCAATGCCCATTTAAGTTTTCATAGTTTGATACCATCTGATGTTAAGATATTTGAAACTATAATACATTCTACCTGGTGGCCAAATGGCAAAAAAGTAATCAAGTGTAAATTGTGTGGTCTAATATTTGTGACTATGGCCAAACTAAGAGAACACTTCTCACTCAAAAACAAGCAGACAATTTGTGCTATTGAAAATCATTCACTTAAAACTTACTCTATTGCTAATCAATATGGATTCGAGTTGCACTTGGAACTAGATTCTGAAACCGAAGTTGAAGACAATGAAGAAAACACAAAGTCTTTAAATTCCTACAACTGTTGCATCTGCAACAAAAGCTTTAAGCgaaaatatgaaataactcaACATCAAAGATCAATGCACAACTACGAATTGTTGGAACTTAAATGCGAACGTTGCATTTTCAAAACAGTCTCACAgAAAGTTTTGGATTACCATAAAGCAACACAGTGttttaatgttgaaaaaaattataaatgtgatcagtgtaattttaaattcatgtGGCAGGAGAATCTGGACAAGCATATTGCAATATATCACACCtctaaagatttttcaaaaacatcGGGCGACATTAACGTGTCAATTTGTGAAGAGTCCACAAAAActgcaaataaaaacaataataattaccaGTTAACATCTGACACTAccactttaaaacattttaaatgtaaCCTTTGCGGAATGTCTTTTCCACGAAATGCCGATTTGCAGAAGCATCGTCAGCGTAAACACACTGGTGAGTGCCACTATAATTGTACCACTTgcgaaaaattattttgcctGCCAATGAAATTACGTCAGCACTTACCACGTTGCCAGAAATCGTTTAATAAAGCTGCCTATTTAAGCCTACATACTCGAGGCCACAACGGAGATAAACCATATGTTTGTGACATTTGCGGTAAAAGATTTGTATGTGCTTCACATCTGAACAGCCATAAAGTGACAGGTCACAACGAATTATGTTCAACGCCAGACAACGAATCCAACTTAAATGTTTCCAATGAACCCGCACCAAGAGAAAAAGCTAAATGTCCAATTTGTGGCTTATTTTTCACCAGTAAGGAAAGACTTAAGTATCACATGAGAATCCACACGGGTGAAAAACTTTACAAATGTGATATTTGCGAAAAAGTCTGTTTACGAAAATCAGATTTAACCGCCCATCGACTTACGCACTTACCAGGTGGCCCATTTAAATGTACAATGTGCTCGCAATCCTTTAAAAAACTATGCCTTTTAAAATTGCATATGCAAAGTCACACTCGTGAAAAATTCTATCACTGCAAGATTTGTTCGAAACAATTTAccacatatacatatttagaaCTTCATATGCGTTATCATACAGGCGAAAAGCCCTTAACGTGA
Protein Sequence: MDTSIKNICFINGVQYKCRTCFDPGSEVFSLAEACKSTQTWRDLLNEVGQLKTNENELLPKTICCKCLTTLISYYDFILQIQNVNKKYFELLAKDNVELQSGADSFTDSLAGSATELPMQQDVTELKFEDEMVVPYDIVLSNSSEMQRVHGYNLENKDDHDPFSEYIKLSAEELEENKREQIDWEKYISAQIEKVNHGNPSCRKAYCSSSSSESDDELPTASQWIPVNMPKYKIEKVGNRFLCPVCMKTFTLKRNCRRHIFTIHAKQNTFACAFCGHHSTCMEYLSTHLSRTHPGQSLHTNANKLALLFGDRLYSKPVVWRFVKCMLCDTIFSTTKKLRQHLANHSDINTLHSLELSSSIVEHWFPNVIDLNHVKEIICKDILEKDWFKYYVVLNEYSYEVSVSDTEVEDLEDESVERASKYNCEISSSSSESDGELPTTSQSIVNKPQDEYEIKKVGNGFLCPVCKETFTFRKNCRRHITSQHSKHNKTFACGFCGHHSTCKEFLRRHLKRAHPGESMHTNAKQLVLLFGDRLYSVPTAWRLVKCMLCHAIFSSTKKLRQHISKHSDPLTLHSLEIKSSIVKHWFPNMIDIIQVKKKICADIREKDWFKYYIVLNEYSYEVSISDTEVEDLEDKTVERASKYNCELCNEKFSYKYQVFSHLKEDHNENDILISCSRCKLEFISIKMYEHHKQTYCENKYKDLSCTHCPGKFIWPENMNNHHCPPKTTVYDATKGHAIFTSVPEVGKNNMYQKDDLETNDDTRIVLPKNVIRCGLCELSFEKLQYLRQHMSMHADGKSGIDFESCIYVKQLRRSSVINYAFLKQQIKTAFIKRQISCFYQAIDKFGNEMDISDSDSDSDSNIEDSDGENVQKAYACDVCKDMFKKRKLLLKHQQERHNAETLPFTCKDCQKQFVSIHLLQQHLKKECWNEHRRIAQPCDICNIRFIWPNNMFVHKEIQHYKMEQNSTGFSKNFKYTLRDKKELDRPNNDNSATAESATSFYPTTAILIKSSSADIQLRYCFLCPKTFFGIEHLNAHLSFHSLIPSDVKIFETIIHSTWWPNGKKVIKCKLCGLIFVTMAKLREHFSLKNKQTICAIENHSLKTYSIANQYGFELHLELDSETEVEDNEENTKSLNSYNCCICNKSFKRKYEITQHQRSMHNYELLELKCERCIFKTVSQKVLDYHKATQCFNVEKNYKCDQCNFKFMWQENLDKHIAIYHTSKDFSKTSGDINVSICEESTKTANKNNNNYQLTSDTTTLKHFKCNLCGMSFPRNADLQKHRQRKHTGECHYNCTTCEKLFCLPMKLRQHLPRCQKSFNKAAYLSLHTRGHNGDKPYVCDICGKRFVCASHLNSHKVTGHNELCSTPDNESNLNVSNEPAPREKAKCPICGLFFTSKERLKYHMRIHTGEKLYKCDICEKVCLRKSDLTAHRLTHLPGGPFKCTMCSQSFKKLCLLKLHMQSHTREKFYHCKICSKQFTTYTYLELHMRYHTGEKPLT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -