Pdom040181.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Polietes domitor
Gene Symbol
topi
Assembly
GCA_947397865.1
Location
OX377618.1:231509863-231514036[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 6e-05 0.011 17.9 2.6 1 23 359 381 359 381 0.97
2 10 0.54 1e+02 5.4 1.0 2 23 417 438 416 438 0.88
3 10 0.0025 0.46 12.8 0.3 2 19 507 524 506 526 0.95
4 10 0.41 76 5.8 1.9 1 22 575 596 575 599 0.90
5 10 1.4 2.6e+02 4.1 0.4 2 21 614 633 613 636 0.81
6 10 1.3e-06 0.00024 23.1 1.9 1 23 656 678 656 678 0.95
7 10 0.0044 0.81 12.0 1.1 1 23 684 709 684 709 0.95
8 10 1.5 2.8e+02 4.0 1.9 1 23 715 737 715 737 0.88
9 10 5.6e-08 1e-05 27.4 0.4 1 23 743 765 743 765 0.99
10 10 0.033 6.1 9.2 1.8 3 23 773 794 771 794 0.95

Sequence Information

Coding Sequence
ATGAACTCAAATGAGGAGGATTTTGCCGGTTCTGATGCTTGGCTCTCAGAACAATTCTTTACGCAACTGAAAGATTTCAATTCTGAATATAAAGAACGTTTTGCCAATAATGAATTTATGATGAATGATGTATTTCATACTTATCCTAATCCAGATATCGGTGGAGAACTTTCAACTTTGGATATGCATGCTTATGATTTATCGATGCCGCGTTTAGAAACATGTGAAACTAGTTTCAGGAGAAATCAAACGGCGGAGAATTATGATATTAAATCAGAAATTTTGGATCTAAGTTGTAGGAATGTAGAACAACCTTCGTTGCCCTTTGGGTCTGCTGTTGGCGGCGTGTCCTTCAATTTTCCCAGTAAAGCTATAGATCTAACAACTGCAGCACAAATGATTTCTGCGCCTCTTGCAAACAATGTAGGAGGAATGATGGGACAAGGCGTCGGTCACAATAATATTCCGCAATTTGATTCTGTAGAAGATGAACTGGAGTTGCTAAGATATTTGGAAGAGCAACCTAAAAACACAACTATAGATCCGTCAATCTACTTAGCTCCACAGCTGCAGCCGCCGCTGCCTTATGCAGTCTATGGTATCATTAAGTGTACTAATTGCAATAATTTGTTTGATGCAGTCGCATTTCAAAACCACGTATGCGGATATAATGAAGTGCAAAATGTTGTACAACAGCTTGAGTTAGCTCCTCCAGTATCTTGTATACCTATATTGCCACCACAAGTACCTACTCCACCTGTATTGTCTCCACCAGTGTCATCCCCACCGGAAGAGGACGAAAAACCTATCAAGGAAGAAGAACCTATATTGCCAGCTGAACCAGCTTGTATACGCCTTTTAAGAGAGAACCAAATACGTATAAGGCGTTTCCTCAAAGATGAACTAAAGTATGACATATATTCTGTAAGCAGTGCCAATTCCAATGCGAAGAATATGAACAATTCTACAAACATCAACAACAGTCCTACTGATTCTACTAATACCGATAATTTAAATGCGTCTTCAACTTCAACAGTGTCTACCACAGTTTGTTCCAAGAAACAGGAAGGTCCTCATGAATGTACTTTGTGTGAGAGAAAATTTGTTCATGCTTCAGGTCTACTACGTCACATGGAAAAACATGCTATGGATCTGATACCAACTTCTAATTCGACTACAGGTGGTAAAACCACAGCCTCACAAGGAAGTTCATCATTGCACAACATTAATGGTTTGAGAGTTGTCATTAAATGCACATTATGTGGCCGCATATTCTTTGAACAAAGCATAGCGTTCGCCCATTTATGCTCACATTTTCCCAGCTCGTGGATGGATGAAAAAGAGATAGACAATTGTGCCGATATACCATACGAATCGTACATGGATGATGCTTTAAACTTTCTAAGATTGGAAGCAACAAATGGTGGAGCATCATTCAATACCAATAATGCTCTAAACAATTATCAAGATCACAAGGCACCTGTGTACCTAAAAATGGTTATTTTGACATGTATTCTGCAGTGTGAATTTTGCGATTTCGTATTTTCGGATGTATCTCATTTATTTGCTCATTCTGCTTGCCACCTACCCGAACGGCGTTTTGAGTGTTTCTCCTGTGATATTTATATGAGAACTTCTAAAGAAATTTGCACACATTGGCAGGCCGAATGCGTCTTTATGCGGGAGAACACAAAAGTAAACAAGGCAATATCCCAGCGTTATTTCGTTTGCAACGTTTGCGAGAATAAGTTTCAGTCAATGGATCTACTGCATGAACATCGTTATACATCGTACCATTTCTTTCCGCGCCTAAATAAACGCTTGGGCATTCTACAATTACCCTGTGAATACTGCGAACTTGTGTTTGAGAACGCTCAAGATTGTGTGAATCACTATGAGGACAAACATTATAGAAAGTATCGTCGAGAAAAAGATGGCACAATCAATTCTATTAGAACACGACAATATCTATGTGATGTTTGTGGTAAATCCTATACACAATCTAGTCATTTGTGGCAACATTTAAGATTCCATCAGGGGGTTAAACCGTTTGCCTGTAAAGAACCTGGCTGTACTCGCAAGTTTACCATACGACCAGATTTAAATGATCACATACGCAAGTGTCATACTGGCGAAAGACCCTACCATTGCTTGGTTTGTGATAAACGTTTCCTAACGGGTTCCGTTTTCTATCAGCATCGCCTCATACATCGAGGCGAACGTCGTTATGAATGTGAAGAATGTGGTAAACGTTTCTATCGTGCTGATGCATTAAAAAATCATCAGCGAATACATACAGGCGAAAAACCTTTCGGTTGCCTCTTTTGTACTAAAAACTTTCGTCAGCGTGGTGACCGCGATAAACATATGAGGGCAAGACATTCTCATTTGGATGCTAATGCCCGACTCATGATGCAAATGCAGAAATTGCAGTTGGAAGCCGCCGCGGCTGTAGCAACCCAACAACATAATGTGGTCATTCCGAATAATACTGAATTGGCTTCGTTTAGTGGTATGCATACACCTCAGACAAACAAGGAGAATATCGCACCTTCATCATCGGTTTCGGGAGCTTTTTATGAGCCTTCTAGTGCCAACAGTAATGATAACGATATTGTTATGATCGGTAATGTTGCCTTTCCGAAGACCATGATTGAATCCTTAATATTGGACATTGACGAAGAATCAGTTTTAAAAGCTATGCAACAAAATGCCATGCAATTGTCATAA
Protein Sequence
MNSNEEDFAGSDAWLSEQFFTQLKDFNSEYKERFANNEFMMNDVFHTYPNPDIGGELSTLDMHAYDLSMPRLETCETSFRRNQTAENYDIKSEILDLSCRNVEQPSLPFGSAVGGVSFNFPSKAIDLTTAAQMISAPLANNVGGMMGQGVGHNNIPQFDSVEDELELLRYLEEQPKNTTIDPSIYLAPQLQPPLPYAVYGIIKCTNCNNLFDAVAFQNHVCGYNEVQNVVQQLELAPPVSCIPILPPQVPTPPVLSPPVSSPPEEDEKPIKEEEPILPAEPACIRLLRENQIRIRRFLKDELKYDIYSVSSANSNAKNMNNSTNINNSPTDSTNTDNLNASSTSTVSTTVCSKKQEGPHECTLCERKFVHASGLLRHMEKHAMDLIPTSNSTTGGKTTASQGSSSLHNINGLRVVIKCTLCGRIFFEQSIAFAHLCSHFPSSWMDEKEIDNCADIPYESYMDDALNFLRLEATNGGASFNTNNALNNYQDHKAPVYLKMVILTCILQCEFCDFVFSDVSHLFAHSACHLPERRFECFSCDIYMRTSKEICTHWQAECVFMRENTKVNKAISQRYFVCNVCENKFQSMDLLHEHRYTSYHFFPRLNKRLGILQLPCEYCELVFENAQDCVNHYEDKHYRKYRREKDGTINSIRTRQYLCDVCGKSYTQSSHLWQHLRFHQGVKPFACKEPGCTRKFTIRPDLNDHIRKCHTGERPYHCLVCDKRFLTGSVFYQHRLIHRGERRYECEECGKRFYRADALKNHQRIHTGEKPFGCLFCTKNFRQRGDRDKHMRARHSHLDANARLMMQMQKLQLEAAAAVATQQHNVVIPNNTELASFSGMHTPQTNKENIAPSSSVSGAFYEPSSANSNDNDIVMIGNVAFPKTMIESLILDIDEESVLKAMQQNAMQLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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