Basic Information

Insect: Polia nebulosa
Gene Symbol: -
Assembly: GCA_951329385.1
Location: OX589610.1:20232131-20233228[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 7.2 1.2e+03 2.1 0.4 2 23 178 198 177 198 0.81

2 6 1.1e-05 0.0019 20.4 4.9 1 23 205 227 205 227 0.98

3 6 4.9e-06 0.00084 21.5 1.7 1 23 233 255 233 255 0.99

4 6 0.00045 0.077 15.3 0.7 1 23 261 283 261 283 0.97

5 6 0.24 41 6.7 2.4 1 22 288 309 288 311 0.89

6 6 0.00016 0.027 16.7 0.5 1 23 317 340 317 340 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	7.2	1.2e+03	2.1	0.4	2	23	178	198	177	198	0.81
2	6	1.1e-05	0.0019	20.4	4.9	1	23	205	227	205	227	0.98
3	6	4.9e-06	0.00084	21.5	1.7	1	23	233	255	233	255	0.99
4	6	0.00045	0.077	15.3	0.7	1	23	261	283	261	283	0.97
5	6	0.24	41	6.7	2.4	1	22	288	309	288	311	0.89
6	6	0.00016	0.027	16.7	0.5	1	23	317	340	317	340	0.92

Sequence Information

Coding Sequence: ATGGTATCAACATATCACATAGTAAAGTTGTTCCAAAAGGCGACGTACGAAAGATATCACAGTAGCCTAAAAGACGACAGTGAAGGGTCCGCCACTAACACTAAGTCTCAACAAGATACAACCGAGGACAAAATATGCCGAATTTGTCTCAAAAAAGGTACACTGCCCATTTTTAAAGACCAGGGACCTGATATTTCCGAAGATATTTGCACTTTCGGCGATATCATAATAAGTGAAGACGATGAACATCCTAAGTTCTTATGTGATTGTTGTCTCAAATTACTAGATGCTGCAATATTGTTCAGAAAAACGGCGAAAATATCTGATCAGGTTCTTAGAAGTGCTTCAGCTAAAAGCAATAAACATTCTAGCAAGCCTCGAGACCTAGACAATGAAGAAACTATAAAAGAAAATGCAGAAAATACTTCAGCATCAGTGTTAGAAAACTTCTTCTCGGCCGTGGAAAGCGACAATGACGTGTGTTGTGATAAATCTAAGCCAGTGAGATGCAGGAAGAAGATACCAAAAGTGCAGTGTAGGATATGCTTCAAAATCATCACCAAAGCCTACTACAAGGAGCATTTTGCTCTCCACGACGAAACTGTGGCTAAGTATGTTTGTGATATTTGTGGCAAATCATTTCGCCAAAGATGTTCTTACAGAAACCATTACTTTACACACAGTTCAGAATTTCCTTATAAGTGCACAATATGCCCATACAGAGGACGCCATTCGGGCCTCCTGAAAATTCATATGCGTACTCATACAGGAGATTATAGATACATGTGTACAGAATGTCCTGGCAGGTTTTTAACTAAGAGTAATTTGAACAAGCATGCACTAAAACACAAGGAACCAATGTTCAAATGTGATGCTTGCCATAGAGGATTCCATTCTAAACTTGTTTTAGAAAGACATTTTGAAGCAGATCATTTAGGAATAAAGAATCATATTTGTAATGTTTGTGGAAAAGCATTTGGATACAGAAAGGCAATGATGAGGCATCAACTTGATGTTCATAAAagagaaaagaaattaaatggaAGAACACCGGCTTACATAGAGGCTGAAATAAACCAATTGGAAGATAATTTATAA
Protein Sequence: MVSTYHIVKLFQKATYERYHSSLKDDSEGSATNTKSQQDTTEDKICRICLKKGTLPIFKDQGPDISEDICTFGDIIISEDDEHPKFLCDCCLKLLDAAILFRKTAKISDQVLRSASAKSNKHSSKPRDLDNEETIKENAENTSASVLENFFSAVESDNDVCCDKSKPVRCRKKIPKVQCRICFKIITKAYYKEHFALHDETVAKYVCDICGKSFRQRCSYRNHYFTHSSEFPYKCTICPYRGRHSGLLKIHMRTHTGDYRYMCTECPGRFLTKSNLNKHALKHKEPMFKCDACHRGFHSKLVLERHFEADHLGIKNHICNVCGKAFGYRKAMMRHQLDVHKREKKLNGRTPAYIEAEINQLEDNL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00375841;
90% Identity: iTF_01231120;
80% Identity: iTF_01231120;