Pneb058681.1
Basic Information
- Insect
- Polia nebulosa
- Gene Symbol
- -
- Assembly
- GCA_951329385.1
- Location
- OX589615.1:11033683-11035219[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 9.6e-05 0.016 17.4 0.6 1 23 121 144 121 144 0.95 2 10 0.46 79 5.8 0.0 2 23 171 193 170 193 0.87 3 10 0.014 2.5 10.6 0.5 2 23 216 237 215 237 0.97 4 10 5e-05 0.0085 18.3 0.4 1 23 241 263 241 263 0.98 5 10 1.8 3.1e+02 3.9 3.8 1 14 268 281 268 291 0.85 6 10 0.00017 0.03 16.6 2.0 2 23 299 321 298 321 0.95 7 10 4.3e-05 0.0074 18.5 1.2 2 23 329 351 328 351 0.95 8 10 0.022 3.7 10.0 5.2 1 23 357 379 357 379 0.97 9 10 1.2e-05 0.0021 20.2 2.7 1 23 385 407 385 407 0.98 10 10 0.0011 0.19 14.1 2.5 1 20 413 432 413 436 0.95
Sequence Information
- Coding Sequence
- ATGGTAGCCGAAAGTTGCACTCGGCGCACATTGCGAATAGATATTCGCAAGGAATTTGAAGGAAGATTCCTTCTAGGTCTCGGCTGCGATACAGACATTAAATTAGAACCAAGAGTAAGAGAAATAGTGAAAACACTCATAAAACCGAGATCTACAAAAGCAAAAGGCAAAAAGGTTGACTGGACGGTtacagttcttaaaaaaaatagcaaacaGAGGTTAACCCAAGCAATATTAAGGGTTCCACCTTATAAAGAAGCTGacaaaagagaaaaagaaatcgACAAACATTTGGAGAATATTCGAAACGTACTCTTGCATTCAAATGCTACTCCTATTTCAAGTCACACAGGGACTGGTTATGTGTGCGGGTTCTGTCCAGAGCACTTTACCACGCCGGGTGATCTCAAGATACATACACTTCAAAAACATGataaatcaagaaaaagtgattTCATGAGAGGCTGCATTTTATCTTCGTATATCGTAAAACTCGACATCACAGGTCTAAAGTGCGAAATATGCGGACGGGATATTGACGGATTAGAACCATTGATGAATCATTTACAATTTgaacacaataaaattatacacaCTGATATCAAAAATCATATTCTGCCTTTTAAATTTATAGACGACACGTTAAAGTGCGTGCTCTGCCCTGAAATCAGCGACCATTTCAAGTTACTACAAAACCACATGAATGTGCACTACGACAATTATAACTGTGGAATCTGTAACTCACCTTTCATTAATAAGAAGGCCCTTAAAAATCATATGGATAGGCACAAACAAGGAGAGTTTCCTTGTCAGTTTTGTTCAAAAGTATTTGACACAAACGACAAAAAATCTTGTCATGAAAAGTACGTACATATTAATggctataaaaaaaacaaatgtccaCATTGCGATGAGAAATTCACTTCTTATTCACAGAGGAATGAACATATGGTGAAAGTCCATGGTGTAGAGCCTCGTGTCCTCAAATGTATGGCTTGTGAAAAATCCTTTACTTCAAAAGAGGCATTGACTCGACACACTAAACGTGACCATTTACTTGAAAGAAAACATGAATGCGAACACTGCGACATGAAATTTTATGGAAAGAAAGAACTGAGATTTCACATGTTGAAACATACCGGCGAAAAGCAACATAAATGTGATGTATGTTTCAAAGCTTTCGGACGCAAATATACTTTAAAAGAGCACTTGAGAATACATGCGGGCGACAGGAGATTCAAATGTGAACAGTGTGATCAAGCGTTTGTGCAGAAATGCAGCTGGAAAAACCATATGTGGTCGCGACATCATGAGCGGGTTTAA
- Protein Sequence
- MVAESCTRRTLRIDIRKEFEGRFLLGLGCDTDIKLEPRVREIVKTLIKPRSTKAKGKKVDWTVTVLKKNSKQRLTQAILRVPPYKEADKREKEIDKHLENIRNVLLHSNATPISSHTGTGYVCGFCPEHFTTPGDLKIHTLQKHDKSRKSDFMRGCILSSYIVKLDITGLKCEICGRDIDGLEPLMNHLQFEHNKIIHTDIKNHILPFKFIDDTLKCVLCPEISDHFKLLQNHMNVHYDNYNCGICNSPFINKKALKNHMDRHKQGEFPCQFCSKVFDTNDKKSCHEKYVHINGYKKNKCPHCDEKFTSYSQRNEHMVKVHGVEPRVLKCMACEKSFTSKEALTRHTKRDHLLERKHECEHCDMKFYGKKELRFHMLKHTGEKQHKCDVCFKAFGRKYTLKEHLRIHAGDRRFKCEQCDQAFVQKCSWKNHMWSRHHERV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00300584;
- 90% Identity
- -
- 80% Identity
- -