Basic Information

Gene Symbol
prdm10
Assembly
GCA_002278615.1
Location
CM008235.1:9068743-9071896[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 2.2e-06 0.00019 21.9 0.7 1 23 259 282 259 282 0.97
2 13 2.5e-05 0.0022 18.6 2.8 1 23 395 417 395 417 0.97
3 13 0.079 7 7.6 0.3 1 19 421 439 421 439 0.94
4 13 4.3e-05 0.0038 17.9 2.2 1 23 451 473 451 473 0.98
5 13 0.23 21 6.1 1.2 1 19 477 495 477 497 0.85
6 13 1.4e-06 0.00012 22.6 3.3 1 23 508 531 508 531 0.97
7 13 0.0038 0.33 11.7 0.1 3 23 544 564 542 564 0.96
8 13 0.00039 0.035 14.8 3.3 1 23 569 591 569 591 0.98
9 13 0.00027 0.023 15.4 2.8 1 23 596 618 596 618 0.98
10 13 4.1e-05 0.0036 17.9 0.4 1 23 624 647 624 647 0.96
11 13 0.00012 0.011 16.4 2.0 2 23 653 675 652 675 0.94
12 13 0.0011 0.098 13.4 2.9 1 23 682 705 682 705 0.96
13 13 1.1e-05 0.00097 19.7 4.6 1 23 710 733 710 733 0.97

Sequence Information

Coding Sequence
atggatATTTCATTACCACCGTGCTTTTCTCTTATAACAAAAGATGAAAGTGATAATaacttattagaaataaatacgggttGTTGTGTGTGCGGAGAAGAACATGAAACAgaaaaatgttcaattttcGATAATTTGATACATgttaaagataaaaaagttCCACCAAGAGCTTTGTTAACCATTCCGCCAAGTTTACGATTAGAAACTTTGGCGGATGGATCGAAAACAATTATTGCGGAAAAAGTGTTTTCAAAAGGAATTCAATTTGgGCCTTACGAGGCTAAACGTTTATATGCGATAAATCCGTTTgatatttttcctttaaaaattttcggtGATTCGGAAAATGTTTTGCCTTTACCTGATTGTTATCTTGATACCAAAAATGAGGAACATTGTAACTGGTTGTGCTATATAGCTGCTGCTAATAATTTAgaagaacaaaatttaatttgttatcaaCttaaaaacgatattttttattctgtaatCCGCGATATTCAACCTGGTGAACAATTAAAAGTCTGGTACTCATCATATTATGCTTCAAAACTTGGAGTTAAACTTCATTCTCCGAAAAAAATTACACATGAATTTTTAGacgatgCTGAAAAAATTCAGGAAATTGCTGAAAAATTACCTCCAAATAAATTAGGTGTTACTGAAGCAAAACAAAATTGGTGTTGCAAATTTTGTAGCCATATCGAATCAAATGTAGTTAAATTTGCGAAACATTtgcaaaaacattataaaaaaatgatagaaaatttttttaattgtgatATTTGCAATGCTGGGTTTagtacaaaaaatttattaaaaaaacatctaCGTACTGTTCATATTGTTTTCACTGGTATTGGAGTAAATGATAAACAAGATAATTATCCGTCTTATAAATCTGATTgttcaaaaatagatttaattgaaACTTGTATGCCTTTACcgatagataatttaattaatgagaCTTTAGCTGACTCAGATCCAAATTTACTTATGTTAGATCAATTAAACACTGGATTATATAATGATCTTAATGATGTAGACGCGTTGAGAGCTATTCTTTGTGATGATAACACAAAAGCTAGTAAAATTGCTCAAGAAAAAAGTATTGCAGATTTTAGTTTAGAATTAGTCGAAAGTAATGAAATACCAAAAATGCAAATGCAACCACCGTTTATTTgtgatatttgcaataaatcatttcaaaatttagattatttacatAGGCATTTAAGTAAACATACTGGCGAATTTACTTGTATTCAATGTTTAGagGTTTTTACGCGTAAAGAAAACTATATCCGCCACCCTTGTTTAATCGCAAAAAATTGCGATCAAAGATTTAATTGTcctttttgtcaaaaaatatttttacaaaataaatatttgcgccGGCATATGAGAATccatttagataaatatcttTGCAACGAATGCGgtaaagaatataattctttaacagaaaaaaatgaacataatTGTGCATCGATTCCCGACgacgaaaaaaatttatttaattgtacattATGCGAAAAACGTTTCACTAGAAAAgcatatttgcaaaaacataTCCGtcgatttcataaaaaaacgaataaagaagaaactaaacatataatatgtgaaatatgcgctgaaacatttaaaaatgttaaagtaTTAAAGTCGCATATTTTATCGCATTCTGAACCAAAATTTGAGTGCAATATTTGTAGTAAGAAGTTCCATAAACCATATGTTTATCAAAATCATATGATGTCTCACGGAACTGCAAAATATACTTGTGAATATTGtacgaaaaaatttaaaacgaaaaaggGACAATTAATGCATATGGTAACTCATAAGCAGATAAAACCGTTTTCATGCAATGAATgtggACAAAATTTCAGACAACGCGTAACTTTAGAATTACATGCTATGAAAGAGCATGATCAAGAAGCGCAAAAATGCACTCAATGCAATCAGAcgtttagtaataaatattcgtaTATAAACCATCTTAATTttgttcataataaaaatcaggGTGATTACAAATGTACCGTTTgtggtttaaagtttttaaaacaatttttattaaaacggcaCATGAACTTTAAGCACAGCAACAAAATATACGTATGTCAATATTGTAATCATTCTTTTAAACAACGTAGTTCAATGCGAaggcatttaaataaagtacatTTAGAAAACAAAGAAGAATGGAATGATCCTTCTGTGATATCATCATTTCTTGTTGATGCAAGTGTTGTGAACCCAttgaaaaatactaataatttagataataataatgaaacttcTAATACTGTTGttgttaaagataataatgcaGATTCAGTTAATACTGAGAATGTGAATGTAAATGAAAACGAAGTGTTATTATCGTTACCTGTTACTGAATATACTGAGATTACAGATCAGCAAATAACTTTAggaaaaaatgcatttatcttAGAAGATGGGACTATAGTGCAACCTCAACCTGAAGGAAATcttatgttttatgttattaatcaataa
Protein Sequence
MDISLPPCFSLITKDESDNNLLEINTGCCVCGEEHETEKCSIFDNLIHVKDKKVPPRALLTIPPSLRLETLADGSKTIIAEKVFSKGIQFGPYEAKRLYAINPFDIFPLKIFGDSENVLPLPDCYLDTKNEEHCNWLCYIAAANNLEEQNLICYQLKNDIFYSVIRDIQPGEQLKVWYSSYYASKLGVKLHSPKKITHEFLDDAEKIQEIAEKLPPNKLGVTEAKQNWCCKFCSHIESNVVKFAKHLQKHYKKMIENFFNCDICNAGFSTKNLLKKHLRTVHIVFTGIGVNDKQDNYPSYKSDCSKIDLIETCMPLPIDNLINETLADSDPNLLMLDQLNTGLYNDLNDVDALRAILCDDNTKASKIAQEKSIADFSLELVESNEIPKMQMQPPFICDICNKSFQNLDYLHRHLSKHTGEFTCIQCLEVFTRKENYIRHPCLIAKNCDQRFNCPFCQKIFLQNKYLRRHMRIHLDKYLCNECGKEYNSLTEKNEHNCASIPDDEKNLFNCTLCEKRFTRKAYLQKHIRRFHKKTNKEETKHIICEICAETFKNVKVLKSHILSHSEPKFECNICSKKFHKPYVYQNHMMSHGTAKYTCEYCTKKFKTKKGQLMHMVTHKQIKPFSCNECGQNFRQRVTLELHAMKEHDQEAQKCTQCNQTFSNKYSYINHLNFVHNKNQGDYKCTVCGLKFLKQFLLKRHMNFKHSNKIYVCQYCNHSFKQRSSMRRHLNKVHLENKEEWNDPSVISSFLVDASVVNPLKNTNNLDNNNETSNTVVVKDNNADSVNTENVNVNENEVLLSLPVTEYTEITDQQITLGKNAFILEDGTIVQPQPEGNLMFYVINQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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