Basic Information

Insect: Pogonocherus hispidulus
Gene Symbol: ZEB2_1
Assembly: GCA_963924545.1
Location: OZ004692.1:115752655-115757379[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 29 0.038 3.9 9.7 4.2 2 23 2 24 1 24 0.93

2 29 0.019 1.9 10.7 6.9 1 23 31 53 31 53 0.97

3 29 4.3e-05 0.0043 19.0 1.1 2 23 60 82 59 82 0.95

4 29 0.00014 0.014 17.4 4.7 1 23 87 109 87 109 0.99

5 29 0.0004 0.041 15.9 0.7 1 23 118 140 118 140 0.95

6 29 8.2e-06 0.00083 21.3 0.2 1 23 145 167 145 167 0.98

7 29 3.6e-06 0.00037 22.4 0.9 1 23 173 195 173 195 0.98

8 29 1.5e-05 0.0016 20.4 2.9 1 23 201 223 201 223 0.97

9 29 7.9e-05 0.008 18.2 1.1 1 23 229 251 229 251 0.98

10 29 1.8e-06 0.00019 23.3 2.1 2 23 260 281 260 281 0.97

11 29 0.03 3.1 10.0 0.4 2 23 287 309 286 309 0.93

12 29 0.014 1.4 11.1 4.3 1 23 315 338 315 338 0.96

13 29 0.0006 0.061 15.4 0.9 1 23 344 367 344 367 0.97

14 29 0.00029 0.029 16.4 1.2 1 23 372 394 372 394 0.97

15 29 5.9e-05 0.006 18.6 1.0 1 23 403 425 403 425 0.98

16 29 4.7e-07 4.7e-05 25.2 1.8 1 23 432 454 432 454 0.97

17 29 9.8e-07 9.9e-05 24.2 0.4 1 23 460 482 460 482 0.98

18 29 6.4e-06 0.00065 21.6 0.6 1 23 488 510 488 510 0.98

19 29 0.12 12 8.2 0.4 1 19 516 534 516 536 0.95

20 29 6e-06 0.00061 21.7 1.0 2 23 541 562 540 562 0.96

21 29 0.0004 0.041 15.9 0.7 2 23 568 590 567 590 0.96

22 29 0.0012 0.12 14.4 0.4 2 23 597 619 596 619 0.96

23 29 0.0042 0.43 12.7 0.7 1 23 625 648 625 648 0.97

24 29 0.00031 0.032 16.3 0.7 1 23 653 675 653 675 0.97

25 29 0.0002 0.021 16.9 1.2 1 23 684 706 684 706 0.98

26 29 5.8e-08 5.9e-06 28.0 2.3 3 23 715 735 714 735 0.98

27 29 2.4e-06 0.00024 23.0 0.4 1 23 741 763 741 763 0.98

28 29 1.9e-06 0.0002 23.2 0.5 1 23 769 791 769 791 0.98

29 29 0.00036 0.036 16.1 2.2 1 21 797 817 797 818 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	29	0.038	3.9	9.7	4.2	2	23	2	24	1	24	0.93
2	29	0.019	1.9	10.7	6.9	1	23	31	53	31	53	0.97
3	29	4.3e-05	0.0043	19.0	1.1	2	23	60	82	59	82	0.95
4	29	0.00014	0.014	17.4	4.7	1	23	87	109	87	109	0.99
5	29	0.0004	0.041	15.9	0.7	1	23	118	140	118	140	0.95
6	29	8.2e-06	0.00083	21.3	0.2	1	23	145	167	145	167	0.98
7	29	3.6e-06	0.00037	22.4	0.9	1	23	173	195	173	195	0.98
8	29	1.5e-05	0.0016	20.4	2.9	1	23	201	223	201	223	0.97
9	29	7.9e-05	0.008	18.2	1.1	1	23	229	251	229	251	0.98
10	29	1.8e-06	0.00019	23.3	2.1	2	23	260	281	260	281	0.97
11	29	0.03	3.1	10.0	0.4	2	23	287	309	286	309	0.93
12	29	0.014	1.4	11.1	4.3	1	23	315	338	315	338	0.96
13	29	0.0006	0.061	15.4	0.9	1	23	344	367	344	367	0.97
14	29	0.00029	0.029	16.4	1.2	1	23	372	394	372	394	0.97
15	29	5.9e-05	0.006	18.6	1.0	1	23	403	425	403	425	0.98
16	29	4.7e-07	4.7e-05	25.2	1.8	1	23	432	454	432	454	0.97
17	29	9.8e-07	9.9e-05	24.2	0.4	1	23	460	482	460	482	0.98
18	29	6.4e-06	0.00065	21.6	0.6	1	23	488	510	488	510	0.98
19	29	0.12	12	8.2	0.4	1	19	516	534	516	536	0.95
20	29	6e-06	0.00061	21.7	1.0	2	23	541	562	540	562	0.96
21	29	0.0004	0.041	15.9	0.7	2	23	568	590	567	590	0.96
22	29	0.0012	0.12	14.4	0.4	2	23	597	619	596	619	0.96
23	29	0.0042	0.43	12.7	0.7	1	23	625	648	625	648	0.97
24	29	0.00031	0.032	16.3	0.7	1	23	653	675	653	675	0.97
25	29	0.0002	0.021	16.9	1.2	1	23	684	706	684	706	0.98
26	29	5.8e-08	5.9e-06	28.0	2.3	3	23	715	735	714	735	0.98
27	29	2.4e-06	0.00024	23.0	0.4	1	23	741	763	741	763	0.98
28	29	1.9e-06	0.0002	23.2	0.5	1	23	769	791	769	791	0.98
29	29	0.00036	0.036	16.1	2.2	1	21	797	817	797	818	0.94

Sequence Information

Coding Sequence: ATGAAATGCGACATCTGCCATAAAATCTGCATTACGAACAAGTCTCTGTCTCAACACAAATACATTTACCACTCTAAATCGAAGAAGGTATTCACCTGTAAGTCGTGTGGGAAGATATTCCACAGAAAACAACACTTTCAGTATCACGAGGCACGCCATCTGAAGAACTTCAAAATCAAGTGTCGCGAGTGTGGGAAAGGCTTTTACAGGAACTCTGACTTGAAACtccatttcgaaacaaaacacAAGAACATCAGATACACGTGTGAAAAATGTGGGAAGTTATATGTGGACTTGTATTGCTTCAAAAGACATCAGCGCACGCACGAGGTCGCTTACACTAGGAAAAATTATAAGTGCATTTCTTGTGAGAAGGTGTACACCACCAGGAGCGGTTTAAACAAGCATATTTTAAGCCATAAAAATGTCGCCTACGTCTGTGATCAATGTGGGATATCTCTGAAGTCTTCCAGCAGTCTTAATAATCACATGATGCTACACAGTGGGGAGAAACCTTTTGTCTGTGATACTTGTGGGAAGAGTTTCAACAAGAAGATGCTGCTCAATGTCCATGAAAGAACTCATACTAAAGAGAAGCCGTACATATGTCAATTTTGTGACAGGAGGTTTACGCAGAAGAGCTCGTTAAATACTCATGTTAAATACCATTCAGGGGAAAGGCCTTATTCCTGTAGGATATGTAAGAAAGGTTATGTTACAAAGACACTACTAAGAAGACATGCCAAAGTTCACGATATAGTaaattcCCGTCGTCCGTCGTGTAAAATATGTGGGAAGTCGTACAGAAACTCAAAAAAACTGAAAAGCCACATGCGAGCGCACAAAAAAAAGACCATCACTTGCGACGTGTGCGGAAAAATGTTTCTGTACAAAAACACAATGGAGAAACATAAGGAATCCGTGCATTTGGCGGGGTACACCCACGAATGCGACTTGTGCGAGAGTAAATTCAAAACGGAGCGCACTCTGAAACAGCACATGCAACACGTACATTTGAAAAATTACGCCTACACATGTGAGACATGTGGGAAGGGTTTTTTCTTCAAGAAGCTACTCGATGTGCACTACAAAGTAGTTCACGAAGAGGTTATGTTCACTTGCGACTCTTGCCACAAACCTTTCAAGACTCTACAAGGTCTGAACACTCATATTGTCATCCATGATCCTTCTTTTAAGAAGCGAGAGTATATTTGTAAAGTATGTTCCTCGGTATTCATCTCTAGGTCTTCCTACACCGTACACATGAGAAAACATAGAGTGGGGGAGGAATGCCACATCTGTGATATTTGTGGGAAGTCCGTTACCAAGAAGGACAGCTTGAAGAACCACATGCGCACGCATACCGGAGAGAAGCCATTTGTTTGCAATATCTGTGGCAGAGGATTCAACACAAATAATCTGTTACGGACTCATTTAAGGATTCATACCGATGAAAAACCCTACGTCTGCAAGATATGCACCAAAGGTTTCAGACAGCGGCCAGCTCTTAAAATCCACTTGAGATACCACACGGGCGAAAAGCCGTATTTCTGTAGGGTGTGCTCGAGAAGTTTCATAAGCGGAACACTGTTAAAGAATCACAGcgaTTTACTCAAAATCCCATGCGAAGTGTGCGGAAAGGTATGTAACGACAGAAAGAAATTGACAAGGCATATGCGAGCCCATAAAAGACGAGACATTTCTTGCGACGTCTgcggaaaattattttcttacaaAAACACCATGGAAAAACATAAACGGAGCGTACACCTAGCAGAAAAGACCCAGGAGTGCACCTTGTGCGGAACCCTGTTCAAAACAGAGCAAACTCTGAATGGACATATGAGGAACATACATCTGAAAAACTACACGTACACTTGCGACACGTGCGGCAAGGGATTTTTCGTAAAGCCTTTGCTTGACCTGCACCATAAAGTTGAGCACGAGGAGGTCAGGTTCAATTGCAACAGTTGCCAGAAGCCTTTCAAGACTCTGCAGGGTCTAAACAGCCATATCGTCACCCACGACCCGACTTTCGAGAGACGTCAGTACATGTGCGAGGAATGCTCGTCGACGTTCTCCTCTAGAACAGCTTACAGCGTGCACATGAGGAAGCACAGAGTGGGGGAAGAACACGAGATCTGTCACATTTGTGGGAAGTCGTTCGCGAGGAAAGGAACCTTGAAAAGTCACATGCGTACGCACACTGGGGAAAAACCGTACGTTTGCAACACTTGCGGGAGGGGTTTCAGCCAAAGCATCATGTTGAGAACGCATTTAAGGATTCACACGGACGAGAAGCCTTATATTTGCACAATTTGCAGTAAGGCGTTCAGACAGAGGCCTGCCCTTAAGATCCACATGAGGTACCATACGGGTGAGAAGCCCTACCGTTGTACAGTATGCCCTAGGAGTTTTGTTAGTCGGACTCTGCTGAAGAATCATAAGTGTTCAGGCCCTAGTAATACATAA
Protein Sequence: MKCDICHKICITNKSLSQHKYIYHSKSKKVFTCKSCGKIFHRKQHFQYHEARHLKNFKIKCRECGKGFYRNSDLKLHFETKHKNIRYTCEKCGKLYVDLYCFKRHQRTHEVAYTRKNYKCISCEKVYTTRSGLNKHILSHKNVAYVCDQCGISLKSSSSLNNHMMLHSGEKPFVCDTCGKSFNKKMLLNVHERTHTKEKPYICQFCDRRFTQKSSLNTHVKYHSGERPYSCRICKKGYVTKTLLRRHAKVHDIVNSRRPSCKICGKSYRNSKKLKSHMRAHKKKTITCDVCGKMFLYKNTMEKHKESVHLAGYTHECDLCESKFKTERTLKQHMQHVHLKNYAYTCETCGKGFFFKKLLDVHYKVVHEEVMFTCDSCHKPFKTLQGLNTHIVIHDPSFKKREYICKVCSSVFISRSSYTVHMRKHRVGEECHICDICGKSVTKKDSLKNHMRTHTGEKPFVCNICGRGFNTNNLLRTHLRIHTDEKPYVCKICTKGFRQRPALKIHLRYHTGEKPYFCRVCSRSFISGTLLKNHSDLLKIPCEVCGKVCNDRKKLTRHMRAHKRRDISCDVCGKLFSYKNTMEKHKRSVHLAEKTQECTLCGTLFKTEQTLNGHMRNIHLKNYTYTCDTCGKGFFVKPLLDLHHKVEHEEVRFNCNSCQKPFKTLQGLNSHIVTHDPTFERRQYMCEECSSTFSSRTAYSVHMRKHRVGEEHEICHICGKSFARKGTLKSHMRTHTGEKPYVCNTCGRGFSQSIMLRTHLRIHTDEKPYICTICSKAFRQRPALKIHMRYHTGEKPYRCTVCPRSFVSRTLLKNHKCSGPSNT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -